Reactome | twz [nucleoplasm]

twz [nucleoplasm]

Stable Identifier

R-DME-8864339

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

KCTD1, D5SHR0

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Drosophila melanogaster)
      - Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Drosophila melanogaster)
        
        KCTD1 binds TFAP2 homo- and heterodimers (Drosophila melanogaster)
        
        TFAP2 homo- and heterodimers:KCTD1 [nucleoplasm] (Drosophila melanogaster)
        
        twz [nucleoplasm] (Drosophila melanogaster)
        
        twz [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:D5SHR0

Gene Names

twz

Reference Genes

BioGPS Gene:37456 twz

ENSEMBL:FBgn0034636

Flybase:FBgn0034636

KEGG Gene (Drosophila melanogaster):Dmel_CG10440 twz

Monarch:37456 twz

NCBI Gene:37456 twz

UCSC:D5SHR0 twz

Reference Transcript

Other Identifiers

147626_at

1626470_at

37456

GO:0002121

GO:0005515

GO:0008049

GO:0008343

GO:0008344

GO:0022414

GO:0023052

GO:0051260

GO:0065003

GO:2000130

Participates

as an input of

KCTD1 binds TFAP2 homo- and heterodimers (Drosophila melanogaster)

as a component of

TFAP2 homo- and heterodimers:KCTD1 [nucleoplasm] (Drosophila melanogaster)

Inferred From

KCTD1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001246449.1, NP_611588.1

Flybase

FBgn0034636

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7KNM2	6	lwr [nucleoplasm] (R-DME-912481) lwr [nucleoplasm] (R-DME-3730619) lwr [cytosol] (R-DME-4655342) lwr [nucleoplasm] (R-DME-3730629) lwr [cytosol] (R-DME-4656944) lwr [nuclear envelope] (R-DME-4655408)	0.621	3
UniProt:Q9VVT4 Q9VVT4			0.488	2
UniProt:Q8SY07 Q8SY07			0.488	2
UniProt:A1Z866 A1Z866			0.488	2

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