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PRKCA [cytosol]
Stable Identifier
R-DME-58196
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P05130
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Drosophila melanogaster)
Non-integrin membrane-ECM interactions (Drosophila melanogaster)
Syndecan interactions (Drosophila melanogaster)
Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG (Drosophila melanogaster)
Protein Kinase C, alpha type: DAG [plasma membrane] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Syndecan-4:PI(4,5)P2:Protein kinase C, alpha type:DAG [plasma membrane] (Drosophila melanogaster)
Protein Kinase C, alpha type: DAG [plasma membrane] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
Activation of conventional Protein Kinase C (Drosophila melanogaster)
Protein Kinase C, conventional [cytosol] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Acetylcholine regulates insulin secretion (Drosophila melanogaster)
Diacylgycerol activates Protein kinase C, alpha type (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Protein Kinase C, alpha type: DAG [plasma membrane] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
DAG and IP3 signaling (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
GRK2 binds CALM1:4Ca2+ (Drosophila melanogaster)
active PKC (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
Protein kinase C (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
PKC phosphorylates GRK2 (Drosophila melanogaster)
active PKC (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
Protein kinase C (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (i) signalling events (Drosophila melanogaster)
Opioid Signalling (Drosophila melanogaster)
G-protein mediated events (Drosophila melanogaster)
PLC beta mediated events (Drosophila melanogaster)
Ca-dependent events (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
GRK2 binds CALM1:4Ca2+ (Drosophila melanogaster)
active PKC (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
Protein kinase C (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
PKC phosphorylates GRK2 (Drosophila melanogaster)
active PKC (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
Protein kinase C (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
Gastrin-CREB signalling pathway via PKC and MAPK (Drosophila melanogaster)
EGFR Transactivation by Gastrin (Drosophila melanogaster)
Activated PKC-alpha activate MMP3 (Drosophila melanogaster)
Protein Kinase C, alpha type: DAG [plasma membrane] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Diacylgycerol activates Protein kinase C, alpha type (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Protein Kinase C, alpha type: DAG [plasma membrane] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by SCF-KIT (Drosophila melanogaster)
Regulation of KIT signaling (Drosophila melanogaster)
PKC alpha interacts with and phosphorylates KIT (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
p-KIT (S741,746):PKC alpha [plasma membrane] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated cell proliferation (Drosophila melanogaster)
PDK1 phosphorylates PKC (Drosophila melanogaster)
PKCA,PKCB,PKCD,PKCZ [cytosol] (Drosophila melanogaster)
PRKCA [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P05130
Reference Genes
BioGPS Gene:48311
CTD Gene:48311
ENSEMBL:FBgn0003091
Flybase:FBgn0003091
KEGG Gene (Drosophila melanogaster):Dmel_CG6622
Monarch:48311
NCBI Gene:48311
Reference Transcript
RefSeq:NM_057334.3
RefSeq:NM_166201.3
RefSeq:NM_001274106.1
Other Identifiers
151905_at
1632478_a_at
48311
GO:0000166
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004697
GO:0004698
GO:0005524
GO:0005886
GO:0006468
GO:0008270
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0023052
GO:0035206
GO:0035556
GO:0036211
GO:0046872
GO:0106310
GO:0140096
GO:2000370
Participates
as a member of
Protein Kinase C, conventional [cytosol] (Drosophila melanogaster)
PKCA,PKCB,PKCD,PKCZ [cytosol] (Drosophila melanogaster)
Protein kinase C (alpha, gamma, delta) [cytosol] (Drosophila melanogaster)
as an input of
PKC alpha interacts with and phosphorylates KIT (Drosophila melanogaster)
Diacylgycerol activates Protein kinase C, alpha type (Drosophila melanogaster)
as a component of
Protein Kinase C, alpha type: DAG [plasma membrane] (Drosophila melanogaster)
p-KIT (S741,746):PKC alpha [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
PRKCA [nucleoplasm]
phospho-p-T497,T638,S657-PRKCA [nucleoplasm]
phospho-p-T500,T642,S661-PRKCB [nucleoplasm]
phospho-p-T500,T642,S661-PRKCB [cytosol]
phospho-p-T500-PRKCB [cytosol]
phospho-p-T497-PRKCA [cytosol]
PRKCB [cytosol]
PRKCB [plasma membrane]
PRKCA [plasma membrane]
PRKCG [cytosol]
phospho-p-T497,T638,S657-PRKCA [cytosol]
phospho-pT497,T638,S657-PRKCA [plasma membrane]
Inferred From
PRKCA [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001261035.1
,
NP_725626.1
,
NP_476682.1
Flybase
FBgn0003091
PRO
P05130
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VX75 Q9VX75
0.488
2
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