Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
phospho-p-S311,Y602 KSR1 [cytosol]
Stable Identifier
R-DME-5672656
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q24171
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
Dual mechanism MAPK inhibitors bind MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
PEBP1 binds activated RAF1 (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates RAF1 (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
PP5 dephosphorylates RAF1 S338 (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
RAF activation (Drosophila melanogaster)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
Phosphorylation of RAF (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
Raf dimer inhibitors bind RAF heterodimers (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
'activator' RAFs [cytosol] (Drosophila melanogaster)
phospho-p-S311,Y602 KSR1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q24171
Reference Genes
BioGPS Gene:40660
CTD Gene:40660
ENSEMBL:FBgn0015402
Flybase:FBgn0015402
KEGG Gene (Drosophila melanogaster):Dmel_CG2899
Monarch:40660
NCBI Gene:40660
UCSC:Q24171
Reference Transcript
RefSeq:NM_001300248.1
RefSeq:NM_079512.3
RefSeq:NM_001300250.1
RefSeq:NM_001300249.1
Other Identifiers
143807_at
1625295_at
40660
GO:0000003
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004713
GO:0005078
GO:0005515
GO:0005524
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0007165
GO:0007173
GO:0007265
GO:0007426
GO:0007427
GO:0007465
GO:0007476
GO:0008293
GO:0008543
GO:0008595
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019900
GO:0023052
GO:0030154
GO:0030295
GO:0036211
GO:0038127
GO:0043410
GO:0045500
GO:0045793
GO:0046579
GO:0046872
GO:0048010
GO:0048856
GO:0048870
GO:0051607
GO:0060090
GO:0070374
GO:0098542
GO:0098590
GO:0098772
GO:0140096
Participates
as a candidate of
'activator' RAFs [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-S311,S406 KSR1 [cytosol]
KSR1 [cytosol]
phospho-p-S311 KSR1 [cytosol]
KSR2 [cytosol]
phospho-p-S311,Y602 KSR1 [plasma membrane]
Inferred From
p-S311,Y602 KSR1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 311 (in Homo sapiens)
Coordinate
311
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 602 (in Homo sapiens)
Coordinate
602
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_001287178.1
,
NP_001287177.1
,
NP_524236.2
,
NP_001287179.1
Flybase
FBgn0015402
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text