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Mer [plasma membrane]
Stable Identifier
R-DME-5669168
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
NF2, Q24564
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Regulation of actin dynamics for phagocytic cup formation (Drosophila melanogaster)
RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)
Mer [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PAKs (Drosophila melanogaster)
NF2 binds PAK1 (Drosophila melanogaster)
Mer [plasma membrane] (Drosophila melanogaster)
PAK1:NF2 [plasma membrane] (Drosophila melanogaster)
Mer [plasma membrane] (Drosophila melanogaster)
RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)
Mer [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q24564
Gene Names
Mer
Reference Genes
BioGPS Gene:32979 Mer
CTD Gene:32979 Mer
ENSEMBL:FBgn0086384
Flybase:FBgn0086384
KEGG Gene (Drosophila melanogaster):Dmel_CG14228 Mer
Monarch:32979 Mer
NCBI Gene:32979 Mer
Reference Transcript
RefSeq:NM_078689.4 Mer
RefSeq:NM_001298529.1 Mer
Other Identifiers
151784_at
1623379_at
32979
GO:0000910
GO:0001558
GO:0001745
GO:0001751
GO:0001934
GO:0003779
GO:0005178
GO:0005515
GO:0005737
GO:0005856
GO:0005886
GO:0005911
GO:0005912
GO:0005938
GO:0006897
GO:0007059
GO:0007112
GO:0007155
GO:0007267
GO:0007283
GO:0007291
GO:0008092
GO:0008285
GO:0008360
GO:0009798
GO:0009887
GO:0009966
GO:0010669
GO:0012501
GO:0014013
GO:0016006
GO:0016020
GO:0016192
GO:0016324
GO:0019094
GO:0022409
GO:0022414
GO:0023052
GO:0030154
GO:0030175
GO:0030182
GO:0032456
GO:0035329
GO:0035330
GO:0035332
GO:0036211
GO:0036375
GO:0042127
GO:0042802
GO:0043065
GO:0043226
GO:0045177
GO:0045463
GO:0045464
GO:0045595
GO:0046621
GO:0046669
GO:0048856
GO:0051307
GO:0060253
GO:0070161
GO:0071944
GO:0072659
GO:0098592
GO:0106037
GO:0120219
GO:0140013
GO:1902115
GO:1902966
GO:2000643
Participates
as an input of
NF2 binds PAK1 (Drosophila melanogaster)
as a component of
PAK1:NF2 [plasma membrane] (Drosophila melanogaster)
This entity regulates
Negatively
RAC1 and CDC42 activate PAK1
(Drosophila melanogaster)
Inferred From
NF2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001285458.1
,
NP_523413.1
Flybase
FBgn0086384
PRO
Q24564
PDB
7EDR
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q24564
1
Mer [plasma membrane]
(R-DME-5669168)
0.692
8
UniProt:P37276
3
DYNC1H1 [extracellular region]
(R-DME-6806223)
DYNC1H1 [azurophil granule lumen]
(R-DME-6799155)
DYNC1H1 [cytosol]
(R-DME-380285)
0.656
4
UniProt:Q9VA38 wts
7
WTS [cytosol]
(R-DME-390037)
Phospho WTS [cytosol]
(R-DME-390056)
Phospho (2 sites) WTS [cytosol]
(R-DME-390013)
phospho-p-S872,T1041-LATS2 [cytosol]
(R-DME-2028565)
phospho-p-S909,T1079-LATS1 [cytosol]
(R-DME-2028551)
LATS1 [cytosol]
(R-DME-2028562)
LATS2 [cytosol]
(R-DME-2028580)
0.556
8
UniProt:P17210
2
KIF5A [cytosol]
(R-DME-983190)
KIF5B [cytosol]
(R-DME-265181)
0.532
3
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