Reactome | Ptip [nucleoplasm]

Ptip [nucleoplasm]

Stable Identifier

R-DME-4570473

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

polySUMO2,3-K1840-MDC1, Q9VUB7

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - SUMOylation (Drosophila melanogaster)
    - SUMO E3 ligases SUMOylate target proteins (Drosophila melanogaster)
      - SUMOylation of DNA damage response and repair proteins (Drosophila melanogaster)
        
        SUMOylation of MDC1 with SUMO2,3 (Drosophila melanogaster)
        
        Ptip [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VUB7

Gene Names

Ptip

Reference Genes

BioGPS Gene:39552 Ptip

ENSEMBL:FBgn0052133

Flybase:FBgn0052133

KEGG Gene (Drosophila melanogaster):Dmel_CG32133 Ptip

Monarch:39552 Ptip

NCBI Gene:39552 Ptip

UCSC:Q9VUB7 Ptip

Reference Transcript

RefSeq:NM_168571.3 Ptip

Other Identifiers

142630_at

148738_at

1626376_at

39552

GO:0002376

GO:0005634

GO:0005654

GO:0006963

GO:0007448

GO:0009880

GO:0036211

GO:0043226

GO:0044666

GO:0048856

GO:0051568

GO:0098542

Participates

as an output of

SUMOylation of MDC1 with SUMO2,3 (Drosophila melanogaster)

Other forms of this molecule

Ptip [nucleoplasm]

phospho-Ptip [nucleoplasm]

Ptip [nucleoplasm]

Inferred From

polySUMO2,3-K1840-MDC1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 1840 (in Homo sapiens)

Coordinate

1840

Modification

polySUMO2,3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_729947.2

Flybase

FBgn0052133

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