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usp [nucleoplasm]
Stable Identifier
R-DME-381319
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
RXRA, P20153
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
Cytoprotection by HMOX1 (Drosophila melanogaster)
Fatty acid ligands activate PPARA (Drosophila melanogaster)
PPARA:RXRA Coactivator complex [nucleoplasm] (Drosophila melanogaster)
Activated PPARA:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA:Corepressors [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Developmental Biology (Drosophila melanogaster)
Adipogenesis (Drosophila melanogaster)
Transcriptional regulation of white adipocyte differentiation (Drosophila melanogaster)
Formation of PPARG:RXRA heterodimer (ARF6 complex) (Drosophila melanogaster)
PPARG:RXRA Heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARG binds PPARG agonists (Drosophila melanogaster)
PPARG:PPARG agonists [cytosol] (Drosophila melanogaster)
PPARG:RXRA:Corepressor Complex [nucleoplasm] (Drosophila melanogaster)
PPARG:RXRA Heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARG:RXRA:Corepressor Complex [nucleoplasm] (Drosophila melanogaster)
PPARG:RXRA Heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Transcriptional regulation of granulopoiesis (Drosophila melanogaster)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Drosophila melanogaster)
CEBPE gene:RARA:RXRA [nucleoplasm] (Drosophila melanogaster)
RARA:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Drosophila melanogaster)
atRA:RARA:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Nuclear Receptor transcription pathway (Drosophila melanogaster)
Formation of NR-MED1 Coactivator Complex (Drosophila melanogaster)
NR [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR-MED1 Coactivator Complex [nucleoplasm] (Drosophila melanogaster)
NR [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Formation of NR-NCOR Corepressor Complex (Drosophila melanogaster)
NR [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR-NCOR CoRepressor Complex [nucleoplasm] (Drosophila melanogaster)
NR [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Carnitine metabolism (Drosophila melanogaster)
CPT1A,B transfers PALM to CAR (Drosophila melanogaster)
RXRA:PPARD:atRA [nucleoplasm] (Drosophila melanogaster)
RXRA:PPARD [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Bile acid and bile salt metabolism (Drosophila melanogaster)
Recycling of bile acids and salts (Drosophila melanogaster)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Drosophila melanogaster)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Drosophila melanogaster)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Regulation of lipid metabolism by PPARalpha (Drosophila melanogaster)
Fatty acid ligands activate PPARA (Drosophila melanogaster)
PPARA:RXRA Coactivator complex [nucleoplasm] (Drosophila melanogaster)
Activated PPARA:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA:Corepressors [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARA binds RXRA (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARA binds fibrates (Drosophila melanogaster)
PPARA:RXRA:Corepressors [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA:fibrates [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA binds Corepressors of PPARA (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA:Corepressors [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
NR1H2 and NR1H3-mediated signaling (Drosophila melanogaster)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Drosophila melanogaster)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NCOR [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Drosophila melanogaster)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NCOA1 recruits EP300 to the ABCA1 promoter (Drosophila melanogaster)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Drosophila melanogaster)
NR1H2,3:RXR [nucleoplasm] (Drosophila melanogaster)
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
CPT1A,B transfers PALM to CAR (Drosophila melanogaster)
RXRA:PPARD:atRA [nucleoplasm] (Drosophila melanogaster)
RXRA:PPARD [nucleoplasm] (Drosophila melanogaster)
usp [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P20153
Gene Names
usp
Reference Genes
BioGPS Gene:31165 usp
CTD Gene:31165 usp
ENSEMBL:FBgn0003964
Flybase:FBgn0003964
KEGG Gene (Drosophila melanogaster):Dmel_CG4380 usp
Monarch:31165 usp
NCBI Gene:31165 usp
Reference Transcript
RefSeq:NM_001272239.2 usp
RefSeq:NM_057433.4 usp
Other Identifiers
153675_at
1622981_at
31165
GO:0000976
GO:0000978
GO:0001046
GO:0001228
GO:0003677
GO:0003700
GO:0003707
GO:0004879
GO:0005102
GO:0005515
GO:0005634
GO:0005694
GO:0005700
GO:0006351
GO:0006355
GO:0006357
GO:0006629
GO:0006697
GO:0007281
GO:0007298
GO:0007552
GO:0008230
GO:0008232
GO:0008270
GO:0008289
GO:0016319
GO:0016322
GO:0022414
GO:0023052
GO:0030154
GO:0030425
GO:0030522
GO:0035073
GO:0035075
GO:0035100
GO:0040034
GO:0042562
GO:0042594
GO:0043226
GO:0043401
GO:0043565
GO:0045596
GO:0045892
GO:0045893
GO:0045944
GO:0046620
GO:0046872
GO:0046982
GO:0048813
GO:0048856
GO:0048870
GO:0060089
GO:0071390
GO:0090575
GO:0140110
Participates
as a component of
NR1H2:RXRA [nucleoplasm] (Drosophila melanogaster)
NR1H3:RXRA [nucleoplasm] (Drosophila melanogaster)
PPARG:RXRA Heterodimer [nucleoplasm] (Drosophila melanogaster)
RARA:RXRA [nucleoplasm] (Drosophila melanogaster)
atRA:RARA:RXRA [nucleoplasm] (Drosophila melanogaster)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Drosophila melanogaster)
RXRA:PPARD [nucleoplasm] (Drosophila melanogaster)
PPARA:RXRA heterodimer [nucleoplasm] (Drosophila melanogaster)
Activated PPARA:RXRA [nucleoplasm] (Drosophila melanogaster)
as an input of
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Drosophila melanogaster)
Formation of PPARG:RXRA heterodimer (ARF6 complex) (Drosophila melanogaster)
PPARA binds RXRA (Drosophila melanogaster)
as a member of
NR [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
usp [cytosol]
phospho-usp [nucleoplasm]
usp [nucleoplasm]
usp [nucleoplasm]
Inferred From
RXRA [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001259168.1
,
NP_476781.1
Flybase
FBgn0003964
PRO
P20153
PDB
1HG4
,
2HAN
,
1R0O
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