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wrd [cytosol]
Stable Identifier
R-DME-3008950
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
PPP2R5D, Q8IN89
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Costimulation by the CD28 family (Drosophila melanogaster)
CTLA4 inhibitory signaling (Drosophila melanogaster)
Dephosphorylation of AKT by PP2A (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-Y307-PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
PP2A dephosphorylates RAF1 (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
RAF activation (Drosophila melanogaster)
PP2A dephosphorylates KSR1 (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates inactive RAFs (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
Degradation of beta-catenin by the destruction complex (Drosophila melanogaster)
AXIN is phosphorylated in the destruction complex (Drosophila melanogaster)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Association of beta-catenin with the destruction complex (Drosophila melanogaster)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Beta-catenin phosphorylation cascade (Drosophila melanogaster)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Drosophila melanogaster)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Drosophila melanogaster)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Drosophila melanogaster)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Drosophila melanogaster)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Degradation of ubiquitinated beta catenin by the proteasome (Drosophila melanogaster)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
Phosphorylation of APC component of the destruction complex (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
PP2A [cytosol] (Drosophila melanogaster)
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
wrd [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8IN89
Gene Names
wrd
Reference Genes
BioGPS Gene:42169 wrd
CTD Gene:42169 wrd
ENSEMBL:FBgn0042693
Flybase:FBgn0042693
Monarch:42169 wrd
NCBI Gene:42169 wrd
UCSC:Q8IN89 wrd
Reference Transcript
RefSeq:NM_169789.2 wrd
Other Identifiers
154512_at
1628476_at
1640602_s_at
42169
GO:0000159
GO:0005634
GO:0005829
GO:0006470
GO:0006914
GO:0007165
GO:0007274
GO:0007528
GO:0012501
GO:0019888
GO:0023052
GO:0034330
GO:0035331
GO:0036211
GO:0043066
GO:0043226
GO:0045202
GO:0046627
GO:0070194
GO:0070328
GO:0072542
GO:0097479
GO:0098772
GO:1904262
Participates
as a candidate of
PP2A regulatory subunit B56 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
wrd [nucleoplasm]
wrd [nucleoplasm]
wrd [cytosol]
Inferred From
PPP2R5D [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_732295.1
Flybase
FBgn0042693
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