Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex

Stable Identifier
R-DME-209129
Type
Reaction [omitted]
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
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Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex
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The free ubiquitinated and phosphorylated Armadillo (ARM) is now targeted by the 26S proteasome which binds and then degrades it. The cytoplasmic concentration of Armadillo is now reduced.
Participants
Input
Output
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as an event of
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Physical Entity
26S proteasome [cytosol] (Drosophila melanogaster)
Activity
endopeptidase activity (GO:0004175)
Authored
Williams, MG  (2006-07-26)
Reviewed
Nusse, R  (2008-01-19)
Created
Williams, MG  (2006-06-28)
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