Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
DREDD [cytosol]
Stable Identifier
R-DME-205876
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Imd pathway (Drosophila melanogaster)
Catalytic processing of the nuclear factor, REL (Drosophila melanogaster)
Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:Phospho REL [plasma membrane] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:REL [plasma membrane] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Activated Phospho IRD5:KEY dimer phosphorylates REL in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:Phospho REL [cytosol] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:REL [cytosol] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Phosphorylated REL is cleaved by and dissociates from DREDD (Drosophila melanogaster)
Phosphorylated REL is cleaved by and dissociates from DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:Phospho REL [plasma membrane] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Phosphorylated REL is cleaved by and dissociates from DREDD in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:Phospho REL [cytosol] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Formation of the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
Assembly of the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Assembly of the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
REL binds to DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:REL [plasma membrane] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
REL binds to monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:REL [cytosol] (Drosophila melanogaster)
DREDD [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8IRY7 Dredd
Gene Names
Dredd, DCP2, CG7486
Chain
propeptide:1-242, chain:243-400, propeptide:401-410, chain:411-494
Reference Genes
BioGPS Gene:31011 Dredd
CTD Gene:31011 Dredd
KEGG Gene (Drosophila melanogaster):Dmel_CG7486 Dredd
Monarch:31011 Dredd
NCBI Gene:31011 Dredd
Reference Transcript
RefSeq:NM_057902.4 Dredd
RefSeq:NM_057903.4 Dredd
RefSeq:NM_057901.4 Dredd
Other Identifiers
152345_at
1639071_a_at
31011
GO:0002230
GO:0002376
GO:0003824
GO:0004175
GO:0004197
GO:0005515
GO:0005737
GO:0005829
GO:0006508
GO:0006915
GO:0006952
GO:0006955
GO:0006963
GO:0006964
GO:0007291
GO:0008233
GO:0008234
GO:0008656
GO:0012501
GO:0016485
GO:0016787
GO:0022414
GO:0023052
GO:0030154
GO:0043069
GO:0045087
GO:0045089
GO:0048856
GO:0048935
GO:0050829
GO:0051604
GO:0061057
GO:0097153
GO:0097194
GO:0097200
GO:0098542
GO:0098772
GO:0140096
Participates
as an input of
Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
Assembly of the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
as a component of
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:REL [plasma membrane] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:Phospho REL [plasma membrane] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:REL [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:Phospho REL [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Dredd [cytosol]
Dredd [cytosol]
Dredd [cytosol]
phospho-Dredd [cytosol]
phospho-Dredd [cytosol]
Dredd [cytosol]
Dredd [cytosol]
Dredd [cytosol]
Dredd [cytosol]
Dredd [cytosol]
Cross References
RefSeq
NP_477251.3
,
NP_477250.3
,
NP_477249.3
Flybase
FBgn0020381
IntEnz
3.4.22.61
PRO
Q8IRY7
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9V3B4 Fadd
2
BG4 [cytosol]
(R-DME-205887)
Fadd [cytosol]
(R-DME-54639)
0.502
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text