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Cul5 [cytosol]
Stable Identifier
R-DME-180528
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
CUL5, Q9VAQ0
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Neddylation (Drosophila melanogaster)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Drosophila melanogaster)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Drosophila melanogaster)
CRL E3 ubiquitin ligases [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
CRL E3 ubiquitin ligases [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Drosophila melanogaster)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
Downregulation of ERBB2 signaling (Drosophila melanogaster)
CUL5 mediates ubiquitination of ERBB2 (Drosophila melanogaster)
Cul5 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VAQ0
Gene Names
Cul5
Reference Genes
BioGPS Gene:43434 Cul5
ENSEMBL:FBgn0039632
Flybase:FBgn0039632
KEGG Gene (Drosophila melanogaster):Dmel_CG1401 Cul5
Monarch:43434 Cul5
NCBI Gene:43434 Cul5
UCSC:Q9VAQ0 Cul5
Reference Transcript
RefSeq:NM_143408.3 Cul5
Other Identifiers
150803_at
1638998_at
43434
GO:0005515
GO:0006511
GO:0007281
GO:0007293
GO:0007295
GO:0007528
GO:0008285
GO:0008582
GO:0016360
GO:0016567
GO:0019005
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0030674
GO:0031146
GO:0031461
GO:0031466
GO:0031625
GO:0034330
GO:0036211
GO:0046426
GO:0048856
GO:0060090
Participates
as a component of
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Cul5-SCF complex [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Cul5 [cytosol]
Inferred From
CUL5 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_651665.2
Flybase
FBgn0288875
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