Reactome | eps15 [cytosol]

eps15 [cytosol]

Stable Identifier

R-DDI-3006481

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

ITSN1, Q54KI4

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Dictyostelium discoideum)

- Membrane Trafficking (Dictyostelium discoideum)
  - Clathrin-mediated endocytosis (Dictyostelium discoideum)
    - AAK1 phosphorylates AP-2 mu subunit at T156 (Dictyostelium discoideum)
      - PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Dictyostelium discoideum)
        
        PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Dictyostelium discoideum)
        
        eps15 [cytosol] (Dictyostelium discoideum)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Dictyostelium discoideum)
        
        eps15 [cytosol] (Dictyostelium discoideum)
    - Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Dictyostelium discoideum)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Dictyostelium discoideum)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Dictyostelium discoideum)
        
        eps15 [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54KI4

Gene Names

eps15

Reference Genes

BioGPS Gene:8626070 eps15

dictyBase:DDB_G0287325

ENSEMBL:DDB_G0287325

KEGG Gene (Dictyostelium discoideum):DDB_G0287325 eps15

Monarch:8626070 eps15

NCBI Gene:8626070 eps15

Reference Transcript

RefSeq:XM_632147.1 eps15

Participates

as a component of

as a candidate of

CDC42 GEFs [cytosol] (Dictyostelium discoideum)

as a member of

Other forms of this molecule

eps15 [cytosol]

eps15 [cytosol]

eps15 [cytosol]

Inferred From

ITSNs [cytosol] (Homo sapiens)

RHOG GEFs [cytosol] (Homo sapiens)

ITSN1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_637239.1

PRO

Q54KI4

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