Reactome | FBXO17 [cytosol]

FBXO17 [cytosol]

Stable Identifier

R-CFA-976036

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

FBXO17, A0A8I3MVV3

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Neddylation (Canis familiaris)
    - AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Canis familiaris)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Canis familiaris)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
      - NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Canis familiaris)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Canis familiaris)
        
        CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
      - CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Canis familiaris)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Canis familiaris)
        
        CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Canis familiaris)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
    - MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Canis familiaris)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Canis familiaris)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
    - NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Canis familiaris)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
        
        F-box protein [cytosol] (Canis familiaris)
        
        FBXO17 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MVV3

Gene Names

FBXO17

Reference Genes

ENSEMBL:ENSCAFG00845004820.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845004820.1 FBXO17

Other Identifiers

484516

GO:0005515

GO:0005737

GO:0019005

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)

as a member of

F-box protein [cytosol] (Canis familiaris)

Inferred From

FBXO17 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000269190

Ensembl

ENSCAFG00845004820, ENSCAFT00845008639, ENSCAFP00845006816

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