Reactome | BTBD1 [cytosol]

BTBD1 [cytosol]

Stable Identifier

R-CFA-8851650

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

BTBD1, A0A8I3MTP7

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Neddylation (Canis familiaris)
    - AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Canis familiaris)
      - NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
      - NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Canis familiaris)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Canis familiaris)
        
        CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
      - CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Canis familiaris)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Canis familiaris)
        
        CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Canis familiaris)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
        
        NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
    - NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Canis familiaris)
      - CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)
      - NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
        
        RBX1:CUL3:BTB [cytosol] (Canis familiaris)
        
        BTB proteins [cytosol] (Canis familiaris)
        
        BTBD1 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MTP7

Gene Names

BTBD1

Reference Genes

ENSEMBL:ENSCAFG00845004133.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845004133.1 BTBD1

Other Identifiers

479057

Cfa.510.1.S1_at

Cfa.7106.1.A1_at

CfaAffx.20424.1.S1_s_at

GO:0000932

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0032991

GO:0036464

GO:0042802

GO:0043226

GO:0097602

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)

as a member of

BTB proteins [cytosol] (Canis familiaris)

Inferred From

BTBD1 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000064726

Ensembl

ENSCAFG00845004133, ENSCAFP00845005865, ENSCAFT00845007413

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