Reactome | RPS19 [cytosol]

RPS19 [cytosol]

Stable Identifier

R-CFA-72343

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

J9P425

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Canis familiaris)

- Nonsense-Mediated Decay (NMD) (Canis familiaris)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Canis familiaris)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Canis familiaris)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        80S ribosome [cytosol] (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        80S ribosome [cytosol] (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)
    - SMG6 hydrolyzes mRNA with premature termination codon (Canis familiaris)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        80S ribosome [cytosol] (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Canis familiaris)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        80S ribosome [cytosol] (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        80S ribosome [cytosol] (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Canis familiaris)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Canis familiaris)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Canis familiaris)
        
        80S ribosome [cytosol] (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Canis familiaris)
        
        80S ribosome [cytosol] (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)
- rRNA processing (Canis familiaris)
  - rRNA processing in the nucleus and cytosol (Canis familiaris)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Canis familiaris)
      - 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Canis familiaris)
        
        40S ribosomal complex [cytosol] (Canis familiaris)
        
        RPS19 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:J9P425

Reference Genes

ENSEMBL:ENSCAFG00000028485

Other Identifiers

476450

484483

CD79A

CD79A-204

Cfa.297.1.S1_s_at

ENSCAFG00000004980

ENSCAFP00000040304

ENSCAFT00000046485

EntrezGene:476450

EntrezGene:484483

EntrezGene:CD79A

EntrezGene:RPS19

GO:0000028

GO:0003674

GO:0003735

GO:0005198

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0008150

GO:0009058

GO:0022607

GO:0022618

GO:0022627

GO:0032991

GO:0034641

GO:0042254

GO:0043226

GO:0065003

IPR001266

IPR018277

IPR036390

IPR038111

P0CAN6

PF01090

RPS19

SM01413

UPI0000161C03

VGNC:38973

XM_005616512

XM_005616513

XP_005616570

Participant Of

hasComponent

40S ribosomal complex [cytosol]

Other forms of this molecule

RPS19 [nucleoplasm]

Inferred From

RPS19 [cytosol] (Homo sapiens)