Reactome | phospho-PPP2R5C [cytosol]

phospho-PPP2R5C [cytosol]

Stable Identifier

R-CFA-6811447

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

p-S337-PPP2R5C, A0A8I3MWU3

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- Intracellular signaling by second messengers (Canis familiaris)
  - PIP3 activates AKT signaling (Canis familiaris)
    - Negative regulation of the PI3K/AKT network (Canis familiaris)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
        
        MAPKs phosphorylate PP2A (Canis familiaris)
        
        p-S368-PPP2R5B,p-S337-PPP2R5C [cytosol] (Canis familiaris)
        
        phospho-PPP2R5C [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MWU3

Gene Names

PPP2R5C

Reference Genes

ENSEMBL:ENSCAFG00845005387.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845005387.1 PPP2R5C

Other Identifiers

480436

Cfa.10495.1.A1_s_at

Cfa.10495.2.S1_at

Cfa.19855.1.S1_s_at

GO:0000159

GO:0007165

GO:0019888

GO:0023052

GO:0098772

Participates

as a member of

p-S368-PPP2R5B,p-S337-PPP2R5C [cytosol] (Canis familiaris)

Other forms of this molecule

PPP2R5C [nucleoplasm]

PPP2R5C [cytosol]

Inferred From

p-S337-PPP2R5C [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 337 (in Homo sapiens)

Coordinate

337

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

OpenTargets

ENSG00000078304

Ensembl

ENSCAFG00845005387, ENSCAFP00845007499, ENSCAFT00845009586

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