Reactome | TMED7 [transport vesicle]

TMED7 [transport vesicle]

Stable Identifier

R-CFA-6808875

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

transport vesicle

Synonyms

TMED7, A0A8I3MVE3

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPI-mediated anterograde transport (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPI-mediated anterograde transport (Canis familiaris)
      - ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
    - Golgi-to-ER retrograde transport (Canis familiaris)
      - COPI-dependent Golgi-to-ER retrograde traffic (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED7 dimer [transport vesicle] (Canis familiaris)
        
        TMED7 [transport vesicle] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MVE3

Gene Names

TMED7

Reference Genes

BioGPS Gene:481436 TMED7

ENSEMBL:ENSCAFG00845005331.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845005331.1 TMED7

KEGG Gene (Canis lupus familiaris):481436 TMED7

Monarch:481436 TMED7

NCBI Gene:481436 TMED7

Reference Transcript

RefSeq:NM_001204338.1 TMED7

Other Identifiers

481436

Cfa.2058.1.A1_at

Cfa.2731.1.S1_at

CfaAffx.1277.1.S1_at

CfaAffx.1277.1.S1_s_at

GO:0005783

GO:0005793

GO:0005794

GO:0043226

Participates

as a component of

TMED7 dimer [transport vesicle] (Canis familiaris)

Other forms of this molecule

TMED7 [endoplasmic reticulum membrane]

TMED7 [endoplasmic reticulum-Golgi intermediate compartment membrane]

TMED7 [Golgi membrane]

Inferred From

TMED7 [transport vesicle] (Homo sapiens)

Cross References

RefSeq

NP_001191267.1

OpenTargets

ENSG00000134970

Ensembl

ENSCAFT00845009486, ENSCAFG00845005331, ENSCAFP00845007416

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