Reactome | NDUFAF7 [mitochondrial matrix]

NDUFAF7 [mitochondrial matrix]

Stable Identifier

R-CFA-6788525

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

mitochondrial matrix

Synonyms

NDUFAF7, A0A8I3NY89

Locations in the PathwayBrowser

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Metabolism (Canis familiaris)

- Aerobic respiration and respiratory electron transport (Canis familiaris)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Canis familiaris)
    - Respiratory electron transport (Canis familiaris)
      - Complex I biogenesis (Canis familiaris)
        
        IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        NDUF subunits bind to form the IP subcomplex (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)
        
        NDUFAF7 [mitochondrial matrix] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NY89

Gene Names

NDUFAF7

Reference Genes

ENSEMBL:ENSCAFG00845019113.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845019113.1 NDUFAF7

Other Identifiers

475725

Cfa.2008.2.A1_at

Cfa.20365.1.S1_s_at

Cfa.3119.1.A1_at

Cfa.3119.1.A1_s_at

GO:0003824

GO:0005515

GO:0005739

GO:0008168

GO:0008757

GO:0016740

GO:0032259

GO:0043226

Participates

as an output of

The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Canis familiaris)

as a component of

NDUFAF7:NDUFS2:2x4Fe-4S [mitochondrial matrix] (Canis familiaris)

Inferred From

NDUFAF7 [mitochondrial matrix] (Homo sapiens)

Cross References

OpenTargets

ENSG00000003509

Ensembl

ENSCAFG00845019113, ENSCAFT00845033849, ENSCAFP00845026488