Reactome | ASAP1 [cytosol]

ASAP1 [cytosol]

Stable Identifier

R-CFA-5620905

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

ASAP1, A0A8I3NS37

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Canis familiaris)

- Cilium Assembly (Canis familiaris)
  - Cargo trafficking to the periciliary membrane (Canis familiaris)
    - VxPx cargo-targeting to cilium (Canis familiaris)
      - ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Canis familiaris)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
      - ASAP1 stimulates GTPase activity of ARF4 (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
      - Cargo-carrying vesicles bud from the TGN (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
      - RAB3IP and RAB8A bind to the ciliary targeting complex (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
      - The exocyst complex binds to RAB3IP in the ciliary targeting complex (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)
      - VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Canis familiaris)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Canis familiaris)
        
        ASAP1 dimer [cytosol] (Canis familiaris)
        
        ASAP1 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NS37

Gene Names

ASAP1

Reference Genes

ENSEMBL:ENSCAFG00845013030.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845013030.1 ASAP1

Other Identifiers

482044

Cfa.10192.1.A1_at

CfaAffx.2516.1.S1_at

GO:0005096

GO:0005515

GO:0005737

GO:0043547

GO:0046872

GO:0098772

Participates

as a component of

ASAP1 dimer [cytosol] (Canis familiaris)

Inferred From

ASAP1 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000153317

Ensembl

ENSCAFP00845018781, ENSCAFT00845023913, ENSCAFG00845013030

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