Reactome | FES [cytosol]

FES [cytosol]

Stable Identifier

R-CFA-396937

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

FES, A0A8I3MKV4

Locations in the PathwayBrowser

Expand all

Developmental Biology (Canis familiaris)

- Nervous system development (Canis familiaris)
  - Axon guidance (Canis familiaris)
    - Semaphorin interactions (Canis familiaris)
      - CRMPs in Sema3A signaling (Canis familiaris)
        
        Tyrosine phosphorylation of CRMPs by Fes (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)
        
        Sema3A:NP-1:Plexin-A:Fes:CRMP [plasma membrane] (Canis familiaris)
        
        Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)
        
        Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)
      - Sema3A PAK dependent Axon repulsion (Canis familiaris)
        
        Activation of PAK by Rac1 (Canis familiaris)
        
        Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Canis familiaris)
        
        Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Canis familiaris)
        
        Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)
        
        Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Canis familiaris)
        
        Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)
        
        Autophosphorylation of PAK (Canis familiaris)
        
        Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Canis familiaris)
        
        Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Canis familiaris)
        
        Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)
        
        Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Canis familiaris)
        
        Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Canis familiaris)
        
        Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)
        
        Phosphorylation of LIMK-1 by PAK (Canis familiaris)
        
        Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Canis familiaris)
        
        Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Canis familiaris)
        
        Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)
        
        FES [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MKV4

Gene Names

FES

Reference Genes

BioGPS Gene:609483 FES

ENSEMBL:ENSCAFG00845002249.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845002249.1 FES

KEGG Gene (Canis lupus familiaris):609483 FES

Monarch:609483 FES

NCBI Gene:609483 FES

Reference Transcript

RefSeq:XM_846743.4 FES

Other Identifiers

609483

Cfa.20624.1.S1_at

CfaAffx.19129.1.S1_s_at

GO:0000166

GO:0001578

GO:0002376

GO:0003824

GO:0004672

GO:0004713

GO:0004715

GO:0005524

GO:0005737

GO:0005856

GO:0005886

GO:0005925

GO:0006468

GO:0007010

GO:0007098

GO:0007155

GO:0008017

GO:0008092

GO:0008289

GO:0008360

GO:0009898

GO:0010976

GO:0015630

GO:0016020

GO:0016192

GO:0016301

GO:0016310

GO:0016740

GO:0018108

GO:0030154

GO:0030155

GO:0031116

GO:0031410

GO:0034987

GO:0035091

GO:0036211

GO:0042127

GO:0043226

GO:0043304

GO:0045595

GO:0045639

GO:0045657

GO:0048856

GO:0048870

GO:0065003

GO:0071305

GO:0140096

GO:2000145

Participates

as a member of

Tyrosine kinases [cytosol] (Canis familiaris)

as a component of

Sema3A:NRP-1:pPlexin-A:Fyn:Fes [plasma membrane] (Canis familiaris)

Inferred From

FES [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_851836.1

OpenTargets

ENSG00000182511

Ensembl

ENSCAFP00845003250, ENSCAFT00845004064, ENSCAFG00845002249