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DCTN2 [cytosol]
Stable Identifier
R-CFA-380302
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
DCTN2, A0A8I3NX29
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Prometaphase (Canis familiaris)
Recruitment of NuMA to mitotic centrosomes (Canis familiaris)
Association of NuMA with microtubules (Canis familiaris)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Translocation of NuMA to the centrosomes (Canis familiaris)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
AURKA Activation by TPX2 (Canis familiaris)
TPX2 binds AURKA at centrosomes (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
TPX2 promotes AURKA autophosphorylation (Canis familiaris)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome maturation (Canis familiaris)
Loss of proteins required for interphase microtubule organization from the centrosome (Canis familiaris)
Loss of C-Nap-1 from centrosomes (Canis familiaris)
cNAP-1 depleted centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Loss of Nlp from mitotic centrosomes (Canis familiaris)
Dissociation of Phospho-Nlp from the centrosome (Canis familiaris)
Nlp-depleted centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome containing phosphorylated Nlp [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Plk1-mediated phosphorylation of Nlp (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome containing phosphorylated Nlp [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Recruitment of mitotic centrosome proteins and complexes (Canis familiaris)
Recruitment of CDK11p58 to the centrosomes (Canis familiaris)
Centrosomes containing recruited CDK11p58 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Recruitment of Plk1 to centrosomes (Canis familiaris)
Centrosome associated Plk1 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Regulation of PLK1 Activity at G2/M Transition (Canis familiaris)
AJUBA binds centrosome-associated AURKA (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome:AURKA:AJUBA [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
AJUBA facilitates AURKA autophosphorylation (Canis familiaris)
Centrosome:AURKA:AJUBA [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
AURKA phosphorylates PLK1 (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
BORA binds PLK1 and AURKA (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Canis familiaris)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
MHC class II antigen presentation (Canis familiaris)
Transport of antigen loaded MHC II molecules to surface (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Kinesins:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Transport to the Golgi and subsequent modification (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPI-mediated anterograde transport (Canis familiaris)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Organelle biogenesis and maintenance (Canis familiaris)
Cilium Assembly (Canis familiaris)
Anchoring of the basal body to the plasma membrane (Canis familiaris)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
C2CD3 binds the mother centriole (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
CP110 and CEP97 dissociate from the centriole (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
MARK4 binds ODF2 in the centriole (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Recruitment of transition zone proteins (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
The distal appendage proteins recruit TTBK2 (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPI-mediated anterograde transport (Canis familiaris)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
Dynein:Dynactin:microtubule [cytosol] (Canis familiaris)
Dynactin [cytosol] (Canis familiaris)
Dynactin arm [cytosol] (Canis familiaris)
Dynactin shoulder [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
DCTN2 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NX29
Gene Names
DCTN2
Reference Genes
ENSEMBL:ENSCAFG00845012256.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845012256.1 DCTN2
Reference Transcript
RefSeq:XM_844581.4 DCTN2
Other Identifiers
100856399
474415
CfaAffx.1314.1.S1_at
CfaAffx.1314.1.S1_s_at
GO:0005737
GO:0005856
GO:0005869
GO:0007017
GO:0030286
GO:0043226
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
Dynamitin tetramer [cytosol] (Canis familiaris)
Nlp-depleted centrosome [cytosol] (Canis familiaris)
centrosome containing phosphorylated Nlp [cytosol] (Canis familiaris)
cNAP-1 depleted centrosome [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
Inferred From
DCTN2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_849674.1
OpenTargets
ENSG00000175203
Ensembl
ENSCAFP00845017149
,
ENSCAFT00845021801
,
ENSCAFG00845012256
© 2024
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