Reactome | ITGA6 [plasma membrane]

ITGA6 [plasma membrane]

Stable Identifier

R-CFA-204439

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

ITGA6(24-1130), A0A8I3SBL1

Locations in the PathwayBrowser

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Cell-Cell communication (Canis familiaris)

- Cell junction organization (Canis familiaris)
  - Type I hemidesmosome assembly (Canis familiaris)
    - BP180 interacts intracellularly with plectin and integrin beta4 (Canis familiaris)
      - Integrin alpha 6:beta 4:Plectin complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha6beta4 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)
      - Integrin alpha6:beta4:Plectin:BP180 complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha 6:beta 4:Plectin complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha6beta4 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)
    - CD151 interacts with BP180 and the integrin alpha 6 subunit (Canis familiaris)
      - BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Canis familiaris)
        
        Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha 6:beta 4:Plectin complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha6beta4 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)
      - CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] (Canis familiaris)
        
        BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Canis familiaris)
        
        Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha 6:beta 4:Plectin complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha6beta4 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)
    - Interaction of Plectin with Integrin beta 4 (Canis familiaris)
      - Integrin alpha 6:beta 4:Plectin complex [plasma membrane] (Canis familiaris)
        
        Integrin alpha6beta4 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)
      - Integrin alpha6beta4 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)

Hemostasis (Canis familiaris)

- Cell surface interactions at the vascular wall (Canis familiaris)
  - Basigin interactions (Canis familiaris)
    - BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Canis familiaris)
      - BSG:Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Canis familiaris)
        
        Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Canis familiaris)
        
        Integrin alpha6beta1 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)
      - Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Canis familiaris)
        
        Integrin alpha6beta1 [plasma membrane] (Canis familiaris)
        
        ITGA6 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3SBL1

Gene Names

ITGA6

Reference Genes

ENSEMBL:ENSCAFG00845028626.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845028626.1 ITGA6

Other Identifiers

100856563

Cfa.19343.1.S1_s_at

CfaAffx.20184.1.S1_s_at

GO:0005886

GO:0006351

GO:0006355

GO:0007155

GO:0008305

GO:0009986

GO:0010668

GO:0012501

GO:0023052

GO:0030154

GO:0030335

GO:0031589

GO:0031994

GO:0035878

GO:0038132

GO:0042327

GO:0043065

GO:0043589

GO:0045944

GO:0048856

GO:0048870

GO:2001237

Participates

as a component of

Inferred From

ITGA6(24-1130) [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000091409

Ensembl

ENSCAFP00845039662, ENSCAFT00845050589, ENSCAFG00845028626

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