Reactome | med-2 [nucleoplasm]

med-2 [nucleoplasm]

Stable Identifier

R-CEL-996772

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

GATA1, G5EF25

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional regulation by RUNX1 (Caenorhabditis elegans)
      - RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)
        
        H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        GATA1:ZFPM1 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)
        
        med-2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EF25

Gene Names

med-2

Reference Genes

BioGPS Gene:191706 med-2

ENSEMBL:WBGene00003181

Monarch:191706 med-2

NCBI Gene:191706 med-2

Wormbase:WBGene00003181

Reference Transcript

RefSeq:NM_066096.1 med-2

Other Identifiers

18513510

191706

A_12_P101287

A_12_P153385

A_12_P155555

CE28867

CE_WBGene00003181_A

CE_WBGene00003181_B

CGZ0027752

GO:0003677

GO:0006351

GO:0006355

GO:0008270

GO:0043565

K04C2.6

K04C2.6_137-196_0.865_21_C

K04C2.6_340-399_0.634_90_B

K04C2.6_406-465_0.909_9_A

K04C2_6P00058

K04C2_6P00256

K04C2_6P00398

cea2.d.32066

Participates

as a member of

Homologues of GATA1 [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

med-2 [nucleoplasm]

Inferred From

GATA1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_498497.1

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