Reactome | KCTD6 [cytosol]

KCTD6 [cytosol]

Stable Identifier

R-CEL-8863321-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

O62200

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Adaptive Immune System (Caenorhabditis elegans)
  - Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
    - Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
      - Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
      - Polyubiquitination of substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
      - Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
      - Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Neddylation (Caenorhabditis elegans)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Caenorhabditis elegans)
        
        CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Caenorhabditis elegans)
        
        RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Caenorhabditis elegans)
        
        BTB proteins [cytosol] (Caenorhabditis elegans)
        
        Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)
        
        KCTD6 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O62200

Reference Genes

ENSEMBL:WBGene00009315

UCSC:O62200

Wormbase:WBGene00009315

Reference Transcript

RefSeq:NM_001264736.1

Other Identifiers

178814_at

18468956

185191

CE17745

CGZ0019255

CGZ0019256

F32B4.5

F32B4.5_185-244_0.852_23_C

F32B4.5_740-799_0.811_32_B

F32B4_5P00242

F32B4_5P00440

F32B4_5P00763

cea2.i.02140

Participates

as a member of

Homologues of KCTD6 [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

KCTD7 [cytosol]

Inferred From

KCTD6 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001251665.1

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