Reactome | NR1H4-G97-SUMO1 [nucleoplasm]

NR1H4-G97-SUMO1 [nucleoplasm]

Stable Identifier

R-CEL-4755434

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

P55853

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - SUMOylation (Caenorhabditis elegans)
    - SUMO E3 ligases SUMOylate target proteins (Caenorhabditis elegans)
      - SUMOylation of intracellular receptors (Caenorhabditis elegans)
        
        SUMOylation of NR1H4 with SUMO1 (Caenorhabditis elegans)
        
        2SUMO1:NR1H4:chenodeoxycholate [nucleoplasm] (Caenorhabditis elegans)
        
        NR1H4-G97-SUMO1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P55853

Reference Genes

BioGPS Gene:266820

dbSNP Gene:266820

ENSEMBL:WBGene00004888

KEGG Gene (Caenorhabditis elegans):CELE_K12C11.2

Monarch:266820

NCBI Gene:266820

UCSC:P55853

Wormbase:WBGene00004888

Reference Transcript

RefSeq:NM_058441.4

Other Identifiers

18458193

187669_at

266820

5XQM

A_12_P113449

A_12_P130201

AAB67608

CAA67914

CCD72942

CE18056

CE_WBGene00004888_A

CE_WBGene00004888_B

CE_WBGene00004888_C

cea2.c.05105

CGZ0029344

EntrezGene:266820

EntrezGene:smo-1

GO:0000122

GO:0000278

GO:0002119

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005815

GO:0005819

GO:0005856

GO:0006464

GO:0007049

GO:0007059

GO:0007080

GO:0007275

GO:0008150

GO:0009058

GO:0009790

GO:0009792

GO:0016605

GO:0016925

GO:0019899

GO:0031386

GO:0031647

GO:0034502

GO:0034641

GO:0040011

GO:0042592

GO:0042802

GO:0043226

GO:0044389

GO:0045892

GO:0046716

GO:0048856

GO:0051276

GO:0051306

GO:0070194

GO:0071965

GO:0140014

IPR000626

IPR022617

IPR029071

IPR033950

K12C11.2

K12C11.2.1

K12C11.2_209-268_0.519_16_C

K12C11.2_7-66_0.938_2_B

K12C11.2_73-132_0.944_1_A

K12C11_2P00027

K12C11_2P00042

K12C11_2P00167

NP_490842

PF11976

SM00213

smo-1

UPI0000135AE9

WBGene00004888

Participant Of

hasComponent

2SUMO1:NR1H4:chenodeoxycholate [nucleoplasm]

Other forms of this molecule

K14-UBE2I-G97-SUMO1 [nucleoplasm]

PIAS4-G97-SUMO1 [nucleoplasm]

K2592-RANBP2-G97-SUMO1 [nuclear envelope]

K159-VHL-G97-SUMO1 [nucleoplasm]

MDM-G97-SUMO1 [nucleoplasm]

ING2-G97-SUMO1 [nucleoplasm]

DDX17-G97-SUMO1 [nucleoplasm]

PARK7-G97-SUMO1 [nucleoplasm]

K1020-EP300-G97-SUMO1 [nucleoplasm]

CTBP1-G97-SUMO1 [nucleoplasm]

K231-SAFB-G97-SUMO1 [nucleoplasm]

SIN3A-G97-SUMO1 [nucleoplasm]

HIPK2-G97-SUMO1 [nucleoplasm]

K499-MBD1-G97-SUMO1 [nucleoplasm]

TOP2B-G97-SUMO1 [nucleoplasm]

TOP1-G97-SUMO1 [nucleoplasm]

TOP2A-G97-SUMO1 [nucleoplasm]

K-PCNA-G97-SUMO1 [nucleoplasm]

MDC1-G97-SUMO1 [nucleoplasm]

STAG2-G97-SUMO1 [nucleoplasm]

RAD21-G97-SUMO1 [nucleoplasm]

K160-PML-G97-SUMO1 [nucleoplasm]

K356-WRN-G97-SUMO1 [nucleoplasm]

RNF168-SUMO1 [nucleoplasm]

XPC-G97-SUMO1 [nucleoplasm]

BRCA1-G97-SUMO1 [nucleoplasm]

NR5A2-G97-SUMO1 [nucleoplasm]

K283-THRA-G97-SUMO1 [nucleoplasm]

K119-NR5A1-G97-SUMO1 [nucleoplasm]

PPARA-G97-SUMO1 [nucleoplasm]

K146-THRB-G97-SUMO1 [nucleoplasm]

HERC2-SUMO1 [nucleoplasm]

UBE2I-G97-SUMO1 [nucleoplasm]

UBA2-G97-SUMO1 [nucleoplasm]

SUMO1 [nucleoplasm]

SUMO1(2-101) [nucleoplasm]

TFAP2C-G97-SUMO1 [nucleoplasm]

HIST1H4-G97-SUMO1 [nucleoplasm]

K1971-CHD3-G97-SUMO1 [nucleoplasm]

HDAC4-G97-SUMO1 [nucleoplasm]

SATB1-G97-SUMO1 [nucleoplasm]

HDAC2-G97-SUMO1 [nucleoplasm]

K444-HDAC1-G97-SUMO1 [nucleoplasm]

K467-NOP58-G97-SUMO1 [nucleoplasm]

K289-MITF-G97-SUMO1 [nucleoplasm]

SP3-G97-SUMO1 [nucleoplasm]

TP53BP1-G97-SUMO1 [nucleoplasm]

RORA-G97-SUMO1 [nucleoplasm]

Inferred From

NR1H4-G97-SUMO1 [nucleoplasm] (Homo sapiens)

K132-NR1H4-G97-SUMO1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via sumoylated lysine at 97 and 289 (in Homo sapiens)

Coordinate

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_490842.1

PRO

P55853

PDB

5XQM

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q94420	1	SPOP [nucleoplasm] (R-CEL-5635035-5)	0.778	5
UniProt:Q95017	3	UBE2I [nucleoplasm] (R-CEL-912481) SUMO1-K14-UBE2I [nucleoplasm] (R-CEL-4085358) SUMO1-C93-UBE2I [nucleoplasm] (R-CEL-3730617)	0.712	5
UniProt:P55853	49	PIAS4-G97-SUMO1 [nucleoplasm] (R-CEL-3968375) K14-UBE2I-G97-SUMO1 [nucleoplasm] (R-CEL-4085334) K2592-RANBP2-G97-SUMO1 [nuclear envelope] (R-CEL-4551627) K159-VHL-G97-SUMO1 [nucleoplasm] (R-CEL-4551713) MDM-G97-SUMO1 [nucleoplasm] (R-CEL-3730829) ING2-G97-SUMO1 [nucleoplasm] (R-CEL-4086096) DDX17-G97-SUMO1 [nucleoplasm] (R-CEL-3900210) PARK7-G97-SUMO1 [nucleoplasm] (R-CEL-4085344) K1020-EP300-G97-SUMO1 [nucleoplasm] (R-CEL-3899290) CTBP1-G97-SUMO1 [nucleoplasm] (R-CEL-3730764) K231-SAFB-G97-SUMO1 [nucleoplasm] (R-CEL-4085364) SIN3A-G97-SUMO1 [nucleoplasm] (R-CEL-4086058) HIPK2-G97-SUMO1 [nucleoplasm] (R-CEL-4090362) K499-MBD1-G97-SUMO1 [nucleoplasm] (R-CEL-4090332) TOP2B-G97-SUMO1 [nucleoplasm] (R-CEL-4641311) TOP1-G97-SUMO1 [nucleoplasm] (R-CEL-4641306) TOP2A-G97-SUMO1 [nucleoplasm] (R-CEL-4641341) K-PCNA-G97-SUMO1 [nucleoplasm] (R-CEL-4615836) MDC1-G97-SUMO1 [nucleoplasm] (R-CEL-4570527) STAG2-G97-SUMO1 [nucleoplasm] (R-CEL-3826645) RAD21-G97-SUMO1 [nucleoplasm] (R-CEL-3826574) K160-PML-G97-SUMO1 [nucleoplasm] (R-CEL-3730884) K356-WRN-G97-SUMO1 [nucleoplasm] (R-CEL-4568845) RNF168-SUMO1 [nucleoplasm] (R-CEL-4551631) XPC-G97-SUMO1 [nucleoplasm] (R-CEL-4570452) BRCA1-G97-SUMO1 [nucleoplasm] (R-CEL-3730735) NR5A2-G97-SUMO1 [nucleoplasm] (R-CEL-4755424) K283-THRA-G97-SUMO1 [nucleoplasm] (R-CEL-4719434) K119-NR5A1-G97-SUMO1 [nucleoplasm] (R-CEL-4546379) NR1H4-G97-SUMO1 [nucleoplasm] (R-CEL-4755434) PPARA-G97-SUMO1 [nucleoplasm] (R-CEL-4341069) K146-THRB-G97-SUMO1 [nucleoplasm] (R-CEL-4719410) HERC2-SUMO1 [nucleoplasm] (R-CEL-4551761) UBE2I-G97-SUMO1 [nucleoplasm] (R-CEL-3730622) UBA2-G97-SUMO1 [nucleoplasm] (R-CEL-3730616) SUMO1 [nucleoplasm] (R-CEL-877304) SUMO1(2-101) [nucleoplasm] (R-CEL-2990831) TFAP2C-G97-SUMO1 [nucleoplasm] (R-CEL-3730823) HIST1H4-G97-SUMO1 [nucleoplasm] (R-CEL-4570549) K1971-CHD3-G97-SUMO1 [nucleoplasm] (R-CEL-8956370) HDAC4-G97-SUMO1 [nucleoplasm] (R-CEL-4615956) SATB1-G97-SUMO1 [nucleoplasm] (R-CEL-4615877) HDAC2-G97-SUMO1 [nucleoplasm] (R-CEL-4616032) K444-HDAC1-G97-SUMO1 [nucleoplasm] (R-CEL-4616028) K467-NOP58-G97-SUMO1 [nucleoplasm] (R-CEL-4570462) K289-MITF-G97-SUMO1 [nucleoplasm] (R-CEL-3730738) SP3-G97-SUMO1 [nucleoplasm] (R-CEL-3730646) TP53BP1-G97-SUMO1 [nucleoplasm] (R-CEL-3730731) RORA-G97-SUMO1 [nucleoplasm] (R-CEL-4719426)	0.712	4
UniProt:P90740 FAN1			0.621	3
UniProt:Q23158	8	ACTN2 [extracellular region] (R-CEL-349725) ACTN1 [extracellular region] (R-CEL-349722) ACTN4 [extracellular region] (R-CEL-349729) ACTN2 [platelet alpha granule lumen] (R-CEL-349727) ACTN1 [platelet alpha granule lumen] (R-CEL-349724) ACTN4 [platelet alpha granule lumen] (R-CEL-198240) ACTN1 [cytosol] (R-CEL-354096) ACTN2 [cytosol] (R-CEL-390562)	0.621	3
UniProt:O16299 FIGL1			0.553	2
UniProt:Q18994	1	EIF2B5 [cytosol] (R-CEL-72523)	0.488	2
UniProt:Q9NF71 Q9NF71			0.488	2
UniProt:Q20952	5	ADD2 [cytosol] (R-CEL-420043) ADD3(2-706) [cytosol] (R-CEL-5226994) ADD1(634-737) [cytosol] (R-CEL-202890) ADD1(1-633) [cytosol] (R-CEL-202891) ADD1 [cytosol] (R-CEL-201623)	0.488	2
UniProt:Q9NA84 Q9NA84			0.488	2
UniProt:Q94361	5	PIAS2-1 [nucleoplasm] (R-CEL-2993785) SUMO1-K35-PIAS4 [nucleoplasm] (R-CEL-3968415) PIAS3 [nucleoplasm] (R-CEL-2993764) PIAS1 [nucleoplasm] (R-CEL-877307) PIAS4 [nucleoplasm] (R-CEL-2993789)	0.488	2
UniProt:O45548 O45548			0.488	2
UniProt:H2KYD4 H2KYD4			0.488	2
UniProt:W03G1.4 Q3V5H0			0.488	2
UniProt:Q17987 Q17987			0.488	2
UniProt:G5EFR3 G5EFR3			0.488	2
UniProt:Q9GZG5 Q9GZG5			0.488	2
UniProt:G5EF87 G5EF87			0.488	2
UniProt:A5JYT9	1	REST [nucleoplasm] (R-CEL-480506)	0.488	2