Reactome | dnc-2 [cytosol]

dnc-2 [cytosol]

Stable Identifier

R-CEL-380302

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

DCTN2, Q09248

Locations in the PathwayBrowser

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Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Asparagine N-linked glycosylation (Caenorhabditis elegans)
    - Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
      - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
        
        COPI-mediated anterograde transport (Caenorhabditis elegans)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
    - COPI-mediated anterograde transport (Caenorhabditis elegans)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
    - Golgi-to-ER retrograde transport (Caenorhabditis elegans)
      - COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynactin [cytosol] (Caenorhabditis elegans)
        
        Dynactin arm [cytosol] (Caenorhabditis elegans)
        
        Dynactin shoulder [cytosol] (Caenorhabditis elegans)
        
        Dynamitin tetramer [cytosol] (Caenorhabditis elegans)
        
        dnc-2 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q09248

Gene Names

dnc-2

Reference Genes

BioGPS Gene:175837 dnc-2

ENSEMBL:WBGene00001018

Monarch:175837 dnc-2

NCBI Gene:175837 dnc-2

UCSC:Q09248 dnc-2

Wormbase:WBGene00001018

Reference Transcript

RefSeq:NM_065885.5 dnc-2

Other Identifiers

175837

18521926

188643_s_at

A_12_P114282

C28H8.12

C28H8.12_516-575_0.919_4_B

C28H8.12_602-661_0.937_1_A

C28H8.12_726-785_0.912_7_C

C28H8_12P00434

C28H8_12P00581

C28H8_12P00880

CE01823

CE_WBGene00001018_A

CE_WBGene00001018_C

CGZ0006508

GO:0005856

GO:0005869

GO:0007017

GO:0043226

WBGene00001018

cea2.c.17578

Participates

as a component of

Dynamitin tetramer [cytosol] (Caenorhabditis elegans)

Inferred From

DCTN2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_498286.1

PRO

Q09248

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