Reactome | BUB1B [cytosol]

BUB1B [cytosol]

Stable Identifier

R-CEL-141436

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

Q21776

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - Mitotic Spindle Checkpoint (Caenorhabditis elegans)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        BUB1B [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        BUB1B [cytosol] (Caenorhabditis elegans)
- Cell Cycle, Mitotic (Caenorhabditis elegans)
  - Regulation of mitotic cell cycle (Caenorhabditis elegans)
    - APC/C-mediated degradation of cell cycle proteins (Caenorhabditis elegans)
      - Regulation of APC/C activators between G1/S and early anaphase (Caenorhabditis elegans)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        BUB1B [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        BUB1B [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21776

Reference Genes

BioGPS Gene:172468

CTD Gene:172468

ENSEMBL:WBGene00000275

Monarch:172468

NCBI Gene:172468

UCSC:Q21776

Wormbase:WBGene00000275

Reference Transcript

RefSeq:NM_059650.4

Other Identifiers

172468

18458603

192167_at

A_12_P118677

CE06251

CE_WBGene00000275_A

CE_WBGene00000275_B

CGZ0031161

GO:0000278

GO:0003824

GO:0004672

GO:0005524

GO:0006468

GO:0007059

GO:0007094

GO:0016740

GO:0023052

GO:0036211

GO:0140014

GO:0140096

R06C7.8

R06C7.8_2272-2331_0.912_22_C

R06C7.8_2387-2446_0.914_19_B

R06C7.8_2570-2629_0.925_11_A

R06C7_8P01705

R06C7_8P02166

R06C7_8P02716

WBGene00000275

cea2.p.15463

Participates

as an input of

Formation of the MCC complex (Caenorhabditis elegans)

as a component of

hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)

Inferred From

BUB1B [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_492051.1

PRO

Q21776

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