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UBE2L6 [cytosol]
Stable Identifier
R-BTA-936014
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
UBE2L6, A0A452DII5
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen processing: Ubiquitination & Proteasome degradation (Bos taurus)
Interaction of E3 with substrate and E2-Ub complex (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Polyubiquitination of substrate (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Transfer of ubiquitin from E1 to E2 (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Bos taurus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Antiviral mechanism by IFN-stimulated genes (Bos taurus)
ISG15 antiviral mechanism (Bos taurus)
Competitive inhibition of translation initiation by ISGylated 4EHP (Bos taurus)
ISGylated 4EHP [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylated 4EHP:mRNA [cytosol] (Bos taurus)
ISGylated 4EHP [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylation of E2 conjugating enzymes (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylation of IRF3 (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylation of host protein filamin B (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylation of host proteins (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylation of protein phosphatase 1 beta (PP2CB) (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylation of protein translation regulator 4EHP (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISGylated 4EHP [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Interaction of E3 ligase with ISG15:E2 complex (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Transfer of ISG15 from E1 to E2 (UBCH8) (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
PKR-mediated signaling (Bos taurus)
ISGylation of PKR (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
Innate Immune System (Bos taurus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)
Negative regulators of DDX58/IFIH1 signaling (Bos taurus)
ISGylation of DDX58 (Bos taurus)
ISG15:DDX58 conjugate [cytosol] (Bos taurus)
ISG15:UBEIL/UbcH8:CEB1 [cytosol] (Bos taurus)
E2 enzymes UbcH8/UBE1L [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
ISG15:UBEIL/UbcH8:CEB1 [cytosol] (Bos taurus)
E2 enzymes UbcH8/UBE1L [cytosol] (Bos taurus)
UBE2L6 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A452DII5
Gene Names
UBE2L6
Reference Genes
ENSEMBL:ENSBTAG00000012989.6
Other Identifiers
509471
GO:0000151
GO:0000166
GO:0000209
GO:0003824
GO:0005524
GO:0005634
GO:0006511
GO:0016740
GO:0030163
GO:0031625
GO:0032020
GO:0036211
GO:0042296
GO:0043226
GO:0061631
GO:0140096
Participates
as an output of
ISGylation of host proteins (Bos taurus)
ISGylation of protein phosphatase 1 beta (PP2CB) (Bos taurus)
ISGylation of E2 conjugating enzymes (Bos taurus)
ISGylation of host protein filamin B (Bos taurus)
ISGylation of PKR (Bos taurus)
ISGylation of IRF3 (Bos taurus)
as a member of
E2 enzymes UbcH8/UBE1L [cytosol] (Bos taurus)
as an input of
Transfer of ISG15 from E1 to E2 (UBCH8) (Bos taurus)
as a component of
ISG15:UBCH8 [cytosol] (Bos taurus)
as a candidate of
E2 Ubiquitin-conjugating enzyme [cytosol] (Bos taurus)
Other forms of this molecule
UBE2L6 [nucleoplasm]
Inferred From
UBE2L6 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000156587
Ensembl
ENSBTAG00000012989
,
ENSBTAP00000017267
,
ENSBTAT00000017267
VGNC
36588
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