Reactome | TNFSF10 [extracellular region]

TNFSF10 [extracellular region]

Stable Identifier

R-BTA-66186

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

E1BE56

Locations in the PathwayBrowser

Expand all

Programmed Cell Death (Bos taurus)

- Apoptosis (Bos taurus)
  - Caspase activation via extrinsic apoptotic signalling pathway (Bos taurus)
    - Caspase activation via Death Receptors in the presence of ligand (Bos taurus)
      - Dimerization of procaspase-8 (Bos taurus)
        
        TRAIL-mediated dimerization of procaspase-8 (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479) [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Bos taurus)
        
        TNFSF10 [extracellular region] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Bos taurus)
        
        TNFSF10 [extracellular region] (Bos taurus)
      - Regulation by c-FLIP (Bos taurus)
        
        FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Bos taurus)
        
        TNFSF10 [extracellular region] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Bos taurus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Bos taurus)
        
        TNFSF10 [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BE56

Reference Genes

BioGPS Gene:507215

ENSEMBL:ENSBTAG00000018994.5

KEGG Gene (Bos taurus):507215

Monarch:507215

NCBI Gene:507215

Reference Transcript

RefSeq:NM_001319901.1

Other Identifiers

507215

GO:0002376

GO:0005125

GO:0005164

GO:0005515

GO:0005576

GO:0005615

GO:0006955

GO:0007005

GO:0007165

GO:0008270

GO:0012501

GO:0016020

GO:0023052

GO:0042802

GO:0043065

GO:0043123

GO:0046872

GO:0048018

GO:0090200

GO:0098772

GO:2001238

Participates

as a component of

TNFSF10:TNFRSF10A,B [plasma membrane] (Bos taurus)

Inferred From

TNFSF10 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001306830.1

Ensembl

ENSBTAP00000025281, ENSBTAG00000018994, ENSBTAT00000025281

VGNC

36172

Cite Us!