Reactome | XRCC2 [nucleoplasm]

XRCC2 [nucleoplasm]

Stable Identifier

R-BTA-5685302

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

XRCC2, F6RZR1

Locations in the PathwayBrowser

Expand all

DNA Repair (Bos taurus)

- DNA Double-Strand Break Repair (Bos taurus)
  - Homology Directed Repair (Bos taurus)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Bos taurus)
      - HDR through Homologous Recombination (HRR) (Bos taurus)
        
        D-loop extension by DNA polymerases (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Homologous DNA Pairing and Strand Exchange (Bos taurus)
        
        CX3 complex binds D-loop structures (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        D-loop formation mediated by PALB2, BRCA2 and RAD51 (Bos taurus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Presynaptic phase of homologous DNA pairing and strand exchange (Bos taurus)
        
        BCDX2 complex formation (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex stabilizes RAD51 filament (Bos taurus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Resolution of D-Loop Structures (Bos taurus)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Bos taurus)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Bos taurus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        MUS81:EME1,EME2 cleaves D-loop (Bos taurus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        XRCC2 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:F6RZR1

Gene Names

XRCC2

Reference Genes

ENSEMBL:ENSBTAG00000030897.4

Other Identifiers

789410

GO:0000400

GO:0000724

GO:0003677

GO:0003824

GO:0005524

GO:0005634

GO:0005657

GO:0005694

GO:0005813

GO:0005815

GO:0005856

GO:0006281

GO:0006310

GO:0033063

GO:0042148

GO:0043226

GO:0140097

GO:0140299

GO:0140657

GO:0140664

Participates

as an input of

BCDX2 complex formation (Bos taurus)

as a component of

BCDX2 complex [nucleoplasm] (Bos taurus)

Inferred From

XRCC2 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000196584

Ensembl

ENSBTAG00000030897, ENSBTAT00000043719, ENSBTAP00000041269

VGNC

37003

Cite Us!