Reactome | RELA [nucleoplasm]

RELA [nucleoplasm]

Stable Identifier

R-BTA-4755466

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

polySUMO3-K37,K122,K123-RELA, A1XG22

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - SUMOylation (Bos taurus)
    - SUMO E3 ligases SUMOylate target proteins (Bos taurus)
      - SUMOylation of immune response proteins (Bos taurus)
        
        PIAS3 SUMOylates RELA with SUMO3 (Bos taurus)
        
        SUMO3-RELA:SUMO3-RELA:DNA [nucleoplasm] (Bos taurus)
        
        SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Bos taurus)
        
        RELA [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:A1XG22

Gene Names

RELA

Reference Genes

BioGPS Gene:508233 RELA

ENSEMBL:ENSBTAG00000013895.6

KEGG Gene (Bos taurus):508233 RELA

Monarch:508233 RELA

NCBI Gene:508233 RELA

Reference Transcript

RefSeq:NM_001080242.2 RELA

Other Identifiers

508233

GO:0000978

GO:0000981

GO:0002376

GO:0003677

GO:0003700

GO:0005737

GO:0006351

GO:0006355

GO:0006954

GO:0007249

GO:0023052

GO:0034097

GO:0038061

GO:0045087

GO:0045944

GO:0071222

GO:0098542

GO:0140110

Participates

as a component of

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Bos taurus)

Other forms of this molecule

RELA [nucleoplasm]

phospho-RELA [nucleoplasm]

RELA [cytosol]

RELA [nucleoplasm]

Inferred From

polySUMO3-K37,K122,K123-RELA [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (polySUMO3 [nucleoplasm]) at 37 (in Homo sapiens)

Coordinate

Modification

polySUMO3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (polySUMO3 [nucleoplasm]) at 122 (in Homo sapiens)

Coordinate

122

Modification

polySUMO3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (polySUMO3 [nucleoplasm]) at 123 (in Homo sapiens)

Coordinate

123

Modification

polySUMO3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_001073711.1

OpenTargets

ENSG00000173039

Ensembl

ENSBTAP00000018453, ENSBTAG00000013895, ENSBTAT00000018453

VGNC

33858

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