Reactome | CXCL9 [extracellular region]

CXCL9 [extracellular region]

Stable Identifier

R-BTA-373856

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

CXCL9, A9QWP9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)
      - The Ligand:GPCR:Gi complex dissociates (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Peptide ligand-binding receptors (Bos taurus)
        
        Chemokine receptors bind chemokines (Bos taurus)
        
        Receptor CXCR3 binds ligands CXCL9 to 11 (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Bos taurus)
        
        CXCR3 ligands [extracellular region] (Bos taurus)
        
        CXCL9 [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:A9QWP9

Gene Names

CXCL9

Reference Genes

BioGPS Gene:513990 CXCL9

ENSEMBL:ENSBTAG00000050852

ENSEMBL:ENSBTAG00000050852.1 CXCL9

KEGG Gene (Bos taurus):513990 CXCL9

Monarch:513990 CXCL9

NCBI Gene:513990 CXCL9

Reference Transcript

RefSeq:NM_001113172.1 CXCL9

Other Identifiers

513990

GO:0002376

GO:0005576

GO:0006935

GO:0006952

GO:0006955

GO:0008009

GO:0048018

GO:0048870

GO:0098772

Participates

as a member of

CXCR3 ligands [extracellular region] (Bos taurus)

Inferred From

CXCL9 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001106643.1

OpenTargets

ENSG00000138755

Ensembl

ENSBTAT00000100670, ENSBTAP00000085237, ENSBTAG00000069240

VGNC

27854