Reactome | CCL28 [extracellular region]

CCL28 [extracellular region]

Stable Identifier

R-BTA-373300

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

CCL28, A6YT15

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CCR10:CCL27,28 [plasma membrane] (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CCR10:CCL27,28 [plasma membrane] (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CCR10:CCL27,28 [plasma membrane] (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CCR10:CCL27,28 [plasma membrane] (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)
      - The Ligand:GPCR:Gi complex dissociates (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CCR10:CCL27,28 [plasma membrane] (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        CCR10:CCL27,28 [plasma membrane] (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Peptide ligand-binding receptors (Bos taurus)
        
        Chemokine receptors bind chemokines (Bos taurus)
        
        Receptor CCR10 binds CCL27 and 28 ligands (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)
        
        CCR10:CCL27,28 [plasma membrane] (Bos taurus)
        
        CCL27,28 [extracellular region] (Bos taurus)
        
        CCL28 [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:A6YT15

Gene Names

CCL28

Reference Genes

BioGPS Gene:535328 CCL28

ENSEMBL:ENSBTAG00000001557.5

KEGG Gene (Bos taurus):535328 CCL28

Monarch:535328 CCL28

NCBI Gene:535328 CCL28

Reference Transcript

Other Identifiers

535328

GO:0001954

GO:0002376

GO:0005125

GO:0005576

GO:0005615

GO:0006935

GO:0006955

GO:0007155

GO:0007165

GO:0008009

GO:0023052

GO:0048018

GO:0048870

GO:0060326

GO:0098772

Participates

as a member of

CCL27,28 [extracellular region] (Bos taurus)

Inferred From

CCL28 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_005221611.1, XP_010815089.1, NP_001094633.1

OpenTargets

ENSG00000151882

Ensembl

ENSBTAT00000002036, ENSBTAG00000001557, ENSBTAP00000002036

VGNC

26953