12150994 |
E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression
Massague, J,
Siegel, PM,
Chen, CR,
Kang, Y
|
Cell |
2002 |
17936557 |
Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia
Polak, L,
Fuchs, E,
Conn, EB,
Guasch, G,
Pasolli, HA,
Schober, M
|
Cancer Cell |
2007 |
9809982 |
Transforming growth factor beta type I receptor kinase mutant associated with metastatic breast cancer
Garrigue-Antar, L,
Chen, T,
Reiss, M,
Carter, D
|
Cancer Res. |
1998 |
19834456 |
4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferation
Susini, C,
Pyronnet, S,
Azar, R,
Bousquet, C,
Alard, A
|
EMBO J. |
2009 |
7777546 |
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
Datto, MB,
Howe, DJ,
Xiong, Y,
Wang, XF,
Panus, JF,
Li, Y
|
Proc. Natl. Acad. Sci. U.S.A. |
1995 |
11477574 |
Novel inactivating mutations of transforming growth factor-beta type I receptor gene in head-and-neck cancer metastases
McNiff, J,
Leffell, D,
Chen, T,
Rimm, DL,
Wells, RG,
Yan, W,
Reiss, M
|
Int. J. Cancer |
2001 |
21358634 |
Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1
Gerdes, AM,
Reversade, B,
Lee, H,
Ferguson-Smith, MA,
Whittaker, S,
Christie, L,
Lane, EB,
Nelson, SF,
Broesby-Olsen, S,
Avery, S,
Szeverényi, I,
Burrows, N,
Stewart, A,
Coats, SE,
Merriman, B,
Hayes, I,
Goudie, DR,
Friedel, J,
D'Alessandro, M,
O'Connor, BD,
Pichert, G,
Lunny, DP,
Verma, C
|
Nat. Genet. |
2011 |
7761852 |
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
Fan, RS,
Sun, L,
Vogelstein, B,
Myeroff, L,
Wang, J,
Kinzler, KW,
Parsons, R,
Markowitz, S,
Zborowska, E,
Lutterbaugh, J
|
Science |
1995 |
8752208 |
TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
Bryson, S,
Fowlis, DJ,
Balmain, A,
Akhurst, RJ,
Ireland, H,
Duffie, E,
Cui, W
|
Cell |
1996 |
7585632 |
Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer
Willson, JK,
Vogelstein, B,
Myeroff, L,
Kinzler, KW,
Markowitz, SD,
Parsons, R,
Liu, B
|
Cancer Res. |
1995 |
9927040 |
Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers
Kinzler, KW,
Willson, JK,
Grady, WM,
Chang, J,
Vogelstein, B,
Swinler, SE,
Kim, SJ,
Myeroff, L,
Neumann, A,
Brattain, MG,
Lutterbaugh, JD,
Rajput, A,
Markowitz, S,
Thiagalingam, S
|
Cancer Res. |
1999 |
9214508 |
A structural basis for mutational inactivation of the tumour suppressor Smad4
Pavletich, NP,
Lo, RS,
Hata, A,
Shi, Y,
Massagué, J
|
Nature |
1997 |
7664267 |
Missense mutations of the transforming growth factor beta type II receptor in human head and neck squamous carcinoma cells
Garrigue-Antar, L,
Gesmonde, J,
Vellucci, VF,
Muñoz-Antonia, T,
Reiss, M,
Antonia, SJ
|
Cancer Res. |
1995 |
11406536 |
Transforming growth factor-beta receptor type I gene is frequently mutated in ovarian carcinomas
Colligan, B,
Chen, T,
Graff, JR,
Hurst, B,
Dehner, B,
Pemberton, J,
Carter, JH,
Triplett, J
|
Cancer Res. |
2001 |
8078588 |
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
Hannon, GJ,
Beach, D
|
Nature |
1994 |
23139211 |
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer
Mouradov, D,
Jorissen, RN,
Jones, IT,
Tsui, C,
Palmieri, M,
Sieber, OM,
Ward, RL,
Fleming, NI,
Mariadason, JM,
Sakthianandeswaren, A,
Lipton, L,
Moore, J,
Ruszkiewicz, AR,
Busam, D,
Christie, M,
McLaughlin, S,
Gibbs, P,
Zhu, HJ,
Strausberg, RL,
Day, F,
Li, S,
Burgess, AW,
Hawkins, NJ,
Desai, J,
Zhao, Q
|
Cancer Res. |
2013 |
8553070 |
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
Hoque, AT,
Yeo, CJ,
Kern, SE,
Fischer, A,
Weinstein, CL,
Hruban, RH,
Moskaluk, CA,
da Costa, LT,
Hahn, SA,
Schutte, M,
Rozenblum, E
|
Science |
1996 |
2418960 |
Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium
Pittelkow, MR,
Scott, RE,
Moses, HL,
Shipley, GD,
Wille, JJ
|
Cancer Res. |
1986 |
22710176 |
Regulation of EMT by TGF? in cancer
Moustakas, A,
Vanlandewijck, M,
Heldin, CH
|
FEBS Lett. |
2012 |