Reactome: A Curated Pathway Database
Found 10866 matches:
as
Summation:143353
Summation:143355
Summation:143357
Summation:143360
The kinetochore is composed of a number of large protein ne...
A properly assembled Sm core and the m3G cap structure are ...
Cdh1 is degraded by the APC/C during in G1 and G0. This aut...
DNA fragmentation in response to apoptotic signals is achie...
Farnesyltransferase/geranyl-geranyltransferase catalyzes th...
MAPK p38 alpha activates cPLA2 by phosphorylation of two se...
NODAL receptors signal by phosphorylating SMAD2 and SMAD3 (...
PIP2-binding AKT1 E17K mutants are anchored to the plasma m...
SETDB1 (ESET, KMT1E) is one of several protein lysine methy...
The snRNAs, except U6 snRNA, are transcribed by RNA polymer...
(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-chole...
(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-Co...
*Plk1 is shown to phosphorylate Wee1A, an event that is like...
1,2,3,4,5,6-hexakisphosphate (IP6) translocates from the cyt...
1-Acylglycerol-3-phosphate is synthesized from dihydroxyacet...
1-diphospho-2,3,4,5,6-pentakisphosphate (1-PP-IP5) and 3-dip...
11-cis-retinol dehydrogenase (RDH5) and RDH11 catalyse the f...
11-cis-retinol dehydrogenase (RDH5) can reversibly catalyse ...
11-cis-specific retinol dehydrogenase (11cRDH) activity foun...
11-deoxycorticosterone is synthesized in a reaction at the e...
11-deoxycortisol is synthesized in a reaction at the endopla...
14-3-3 family proteins can bind Raf1 and have been suggested...
14-3-3 has been displaced from Ser259. 14-3-3 may now bind i...
14-3-3 proteins bind BAD phosphorylated by activated AKT on ...
14-3-3 proteins, represented here as YWHAZ, bind directly to...
14-3-3/YWHAZ and XPO1 both contribute to the CBY1-mediated n...
15-Deoxy-delta 12,14-prostaglandins D2 (15d-PGD2) is a dehyd...
15-Deoxy-delta(12,14)-PDJ2 (15d-PGJ2) is a dehydration produ...
15-hydroxyprostaglandin dehydrogenase (HPGD) converted lipox...
15-Hydroxyprostaglandin dehydrogenase (HPGD) oxidises prosta...
17-alpha-hydroxypregnenolone, NADPH + H+, and O2 react to fo...
17-Hydroxypregnenolone and NAD+ react to form pregn-5-ene-3,...
17-Hydroxyprogesterone, NADPH + H+, and O2 react to form 11-...
17Alpha-hydroxyprogesterone (17aHPROG), NADPH + H+, and O2 r...
18-Hydroxycorticosterone and NADPH + H+ react to form aldost...
19 WNT ligands and 10 FZD receptors have been identified in ...
19 WNT proteins have been identified in human cells. The WN...
19-hydroxyprostaglandins E1 and E2 (19OH-PGE1 and 2) are maj...
2-5A-dependent ribonuclease (RNASEL) is an endoribonuclease ...
2-hexaprenyl-6-methoxyphenol (HMPhOH) aka 2-methoxy-6-hexapr...
2-mercaptoethanol is a typical substrate for Thiol S-methylt...
2-methoxy-6-decaprenylphenol (DMPhOH) is enzymatically conve...
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondr...
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondr...
20alpha,22beta-hydroxycholesterol (20a,22b-DHCHOL), NADPH + ...
22beta-hydroxycholesterol, NADPH + H+, and O2 react to form ...
24-hydroxycholesterol 7-alpha-hydroxylase (CYP39A1), located...
24-hydroxycholesterol is transported from the endoplasmic re...
24-hydroxycholesterol is transported from the extracellular ...
25(R) DHCA-CoA is transported from the cytosol into the pero...
25(R) TetraHCA-CoA is transported from the cytosol into the ...
25(R) THCA-CoA is transported from the cytosol into the pero...
25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is ...
25(S) DHCA-CoA and O2 react to form 25(S) 3alpha,7alpha-dihy...
25(S) THCA-CoA and O2 react to form 3alpha,7alpha,12alpha-tr...
25-hydroxycholesterol (25OH-CHOL) is 7alpha-hydroxylated to ...
25-hydroxycholesterol 7-alpha-hydroxylase (CYP7B1) normally ...
27-hydroxycholesterol is transported from the extracellular ...
27-hydroxycholesterol is transported from the mitochondrial ...
27-hydroxycholesterol, NADPH + H+, and O2 react to form chol...
3,4-dihydroxyphenylacetic acid, generated after oxidation of...
3,5,3'-Triiodothyronine (T3) 4-sulfate is a major metabolite...
3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-chole...
3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-chole...
3,7,24THCA (3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoa...
3,7,24THCA-CoA is transported from the cytosol into the pero...
3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid aka 3-methoxy-4...
3-hydroxy tetracosahexaenoyl-CoA undergoes dehydrogenation t...
3-hydroxy-3-methylglutaryl Coenzyme A synthase (HMG-CoA synt...
3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) catalyzes th...
3-methoxy-4-hydroxy-5-decaprenylbenzoic acid (MHDB) is enzym...
3-methoxytyramine generated by COMT after methylation of dop...
3-methylindole (3MI) is a fermentation product of tryptophan...
3-Oxoacid CoA-transferase dimer (OXCT1) in the mitochondrial...
3-phosphoinositide dependent protein kinase-1 (PDK1) and Pro...
3-phosphoinositide dependent protein kinase-1 (PDK1, also kn...
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al, NADPH + H+, ...
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-...
3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA and...
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA ...
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al, NADP...
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al, NADPH ...
3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA and CoASH re...
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol and NADPH + H...
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol and NADPH + H...
4,4-dimethylcholesta-8(9),24-dien-3beta-ol, NADPH + H+, and...
4-carboxycholesta-8(9),24-dien-3beta-ol and NAD+ react to fo...
4-Cholesten-7alpha, 12alpha-diol-3-one and NADPH + H+ react ...
4-cholesten-7alpha,12alpha,24(S)-triol-3-one and NADPH + H+ ...
4-Cholesten-7alpha,12alpha,27-triol-3-one and NADPH + H+ rea...
4-Cholesten-7alpha,24(S)-diol-3-one, NADPH, and H+ react to ...
4-Cholesten-7alpha,27-diol-3-one, NADPH, and H+ react to for...
4-Cholesten-7alpha-ol-3-one, NADPH, and H+ react to form 5be...
4-cis-decenoyl-CoA transits through the first step of the sa...
4-hydroxybenzoate polyprenyltransferase, mitochondrial (COQ2...
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol and NAD+ re...
4-methylcholesta-8(9),24-dien-3-one and NADPH + H+ react to ...
4-methylcholesta-8(9),24-dien-3beta-ol, NADPH + H+, and O2 r...
4EHP is a member of eukaryotic translation initiation factor...
5'-nucleotidase (NT5E) associated with the plasma membrane c...
5'-nucleotidase (NT5E) associated with the plasma membrane c...
5'-nucleotidase cytosolic IB catalyzes the hydrolysis of AMP...
5'3'-Nucleotidase, mitochondrial (NT5M) is the major nucleot...
5-aminolevulinate is transported from the mitochondrial matr...
5-Aminolevulinic acid dehydratase (ALAD aka porphobilinogen ...
5-HT1 receptors, once bound to serotonin (5-HT), act on the ...
5-hydroperoxy-eicosatetraenoic acid (5-HpETE), 5-hydroxyeico...
5-hydroxyindole acetaldehyde is then catalyzed by aldehyde d...
5-methylcytosine G/T mismatch specific DNA glycosylase is th...
5-oxoprolinase catalyzes the cleavage of 5-oxoproline to for...
5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) is a key inter...
53BP1-deficient DT40 chicken cells exhibit elevated sensitiv...
5beta-cholestan-3alpha, 7alpha, 12alpha, 27-tetrol and NADP+...
5beta-cholestan-3alpha, 7alpha, 26-triol and NADP+ react to...
5beta-cholestan-3alpha, 7alpha-diol is transported from the ...
5beta-cholestan-3alpha, 7alpha-diol, NADPH + H+, and O2 reac...
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol, NADPH...
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is transl...
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, NADPH + ...
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is transloca...
5beta-cholestan-3alpha,7alpha,12alpha-triol is translocated ...
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol, NADPH + H+, a...
5beta-cholestan-3alpha,7alpha,24(S)-triol is transported fro...
5beta-cholestan-3alpha,7alpha,24(S)-triol, NADPH + H+, and O...
5beta-cholestan-3alpha,7alpha,27-triol is transported from t...
5Beta-cholesten-7alpha,12a,27-triol-3-one and NADPH + H+ for...
5Beta-cholesten-7alpha,12alpha,24(S)-triol-3-one and NADPH +...
5Beta-cholesten-7alpha,12alpha-diol-3-one and NADPH + H+ for...
5Beta-cholesten-7alpha,24(S)-diol-3-one and NADPH + H+ form ...
5Beta-cholesten-7alpha,27-diol-3-one and NADPH + H+ form 5be...
5Beta-cholesten-7alpha-ol-3-one and NADPH + H+ form 5beta-ch...
6-mercaptopurine (6MP) is used in the treatment of inflammat...
6-pyruvoyl tetrahydrobiopterin synthase (PTPS) requires pho...
6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (Takikawa et ...
7alpha-hydroxycholesterol and NAD+ react to form 4-cholesten...
80S monosomes dissociate into 40S and 60S ribosomal subunits...
8p11 myeloproliferative syndrome (EMS) is a myeloproliferati...
8p11 myeloproliferative syndrome (EMS) is an aggressive diso...
OVERVIEW OF TRANSCRIPTION REGULATION:

Detail...

THE NOTCH-HLH TRANSCRIPTION PATHWAY:

Notch ...

THE NUCLEAR RECEPTOR-MED1 REACTION: The Nuclear Recep...
De novo (Kennedy pathway) synthesis of phosphatidylch...
De novo (Kennedy pathway) synthesis of phosphatidylet...
M. tuberculosis utilizes myo-inositol-1-phosph...
Mtb bacterioferritin BfrA oxidises Fe2+ to Fe3+, migr...
Mtb bacterioferritin BfrB oxidises Fe2+ to Fe3+, migr...
Mtb encounters a vastly changed environment, soon aft...
Mycobacterium tuberculosis H37Rv is the laboratory st...

Formation of the KRAB ZNF / KAP1 Corepressor Complex:

The P450 isozyme system is the major phase 1 biotransform...
A potential regulator of human copper metabolism has recent...
A 15-hydroxy-eicosatetraenoic acid dehydrogenase (15-HEDH) o...
A beta cell contains about 10 000 secretory granules. Of the...
A bioinformatics approach identified two further human trans...
A broad specificity ATP-competitive inhibitor of FGF-, VEGF-...
A chromosomal aberration involving the nuclear receptor coac...
A classic example of bifunctional transcription factors is t...
A combination of proteomic and bioinformatics analyses of TR...
A complex consisting of XRCC4 and DNA ligase IV is recruited...
A complex consisting of XRCC4 and DNA ligase IV is recruited...
A complex homologous to the Sec translocon in yeast (Meyer e...
A complex of four proteins termed CIA targeting complex is i...
A complex of four proteins termed CIA targeting complex is i...
A costimulatory signal involved in T cell activation is tran...
A current model of the arrangement of subunits within the  T...
A defined subset of the ABC transporter superfamily, the ABC...
A description of the mitotic proteins targeted by the mitoti...
A dimer of T1R2 and T1R3 receptors responds to diverse stimu...
A DNA double strand break results when two single strand bre...
A FA anion diffuses laterally within the membrane towards UC...
A family of antiport, dimeric ATP-ADP translocases (SLC25A...
A family of antiport, ATP-ADP translocases (SLC25A4,5,6), p...
A flavin-dependent monooxygenase involved in ubiquinone/ubiq...
A flavin-dependent monooxygenase involved in ubiquinone/ubiq...
A fourth and fifth mannose is added to the N-glycan precurso...
A fourth mannose is added to the N-glycan precursor by ALG11...
A functional immune system depends on the production of a wi...
A glucuronate (GlcA) moiety is added to the chondroitin chai...
A glycine residue (Gly2) at the N-terminus of eNOS is myrist...
A group of hypomorphic IKBKG mutations has been associated w...
A group of inositol phosphatases and the broad specificity e...
A group of inositol phosphatases dephosphorylate inositol 1,...
A group of myelin components named MDGIs (myelin-derived gro...
A group of phospholipase C proteins (“PLC(degh)”) bind to th...
A GST-tagged recombinant rat Hes1 protein exogenously expres...
A hallmark of human NK cells is the expression of HLA class ...
A hallmark of the human cell cycle in normal somatic cells i...
A highly conserved lysine within the guanylyltransferase (GT...
A human mitochondrion contains about 1500 proteins, more tha...
A key event for Ras transformation involves the direct physi...
A low level of Rac activity is essential to maintain axon ou...
A major known function of the 9-1-1 complex is to recruit Ch...
A mannose is added to the N-glycan precursor via a beta-1,4 ...
A mature mRNA that has been 3' cleaved, subsequently polyade...
A mature mRNA that has been 3' cleaved, subsequently polyade...
A mature, translatable mRNA has a 5' cap structure and 3' po...
A member of the PP2A family of phosphatases dephosphorylates...
A member of the UDPGT (UDP-glucuronosyltransferase) enzyme f...
A membrane-associated TSC1 (hamartin) binds TSC2 (tuberin) a...
A membrane-proximal cytoplasmic region of the advanced glyca...
A methyl group from 5-methyltetrahydrofolate is transferred ...
A molecule of ATP binds to the large cleft on the side of th...
A molecule of extracellular bile salt (glyco- or taurocholat...
A molecule of extracellular bile salt (glyco- or taurocholat...
A molecule of extracellular bile salt or bile acid (cholate,...
A molecule of extracellular glycocholate (GCCA) or taurochol...
A molecule of extracellular glycocholate or taurocholate is ...
A molecule of glycocholate, glycochenodeoxycholate, taurocho...
A molecule of glycocholate, taurocholate, or taurochenodeoxy...
A new centromeric nucleosome containing histone H2A, histone...
A Novartis tyrosine kinase inhibitor with activity against m...
A novel cytochrome P450, CYP2U1, may play an important role ...
A novel pathway has been described for ODC degradation durin...
A number of CYPs can act upon vitamins.
A number of CYPs take part in cholesterol biosynthesis and e...
A number of different extracellular signals converge on PI3K...
A number of genetic disorders are caused by mutations in the...
A number of inactive tetrameric PKA holoenzymes are produced...
A number of membrane proteins destined for the ciliary membr...
A number of MHC Class I molecules a known bind differentiall...
A number of myristoylated proteins have been shown to traffi...
A number of proteins, including eight required for normal bl...
A number of receptors and cell adhesion molecules play a key...
A number of SET1-type complex proteins are pulled down from ...
A number of skeletal and developmental diseases have been sh...
A number of so called non-canonical WNT ligands have been sh...
A number of ubiquitin moeities are covalently added to the C...
A pan-FGFR ATP-competitive inhibitor that is in phase I clin...
A partially deadenylated mRNA has about 80 3' adenosine resi...
A phosphatidyl-pyridinium bisretinoid compound, A2PE, is for...
A poly-uridine sequence motif, consisting in most cases of 5...
A portion of PDPK1 (PDK1) is anchored to the plasma membrane...
A portion of SOD1 is located in the mitochondrial intermembr...
A portion of the p75NTR ICD produced by gamma-secretase clea...
A proper assembly of repair complex may require displacement...
A protein phosphatase MTMR4, residing in the early endosome ...
A recent potential regulator of human copper metabolism has ...
A recently discovered protein called malectin is known to re...
A recombinant dog (Canis familiaris) RHPN2 (rhophilin-2) bin...
A recombinant mouse Fmnl1 binds a recombinant mouse Cdc42, a...
A recombinant mouse NICD1 was shown to be ubiquitinated upon...
A redox exchange between leucodopachrome (cyclodopa) and dop...
A regulated balance between cell survival and apoptosis is e...
A regulated balance between cell survival and cell death is ...
A second glucose is removed from the N-linked glycan. The re...
A second mannose is added to the N-glycan precursor via an a...
A second N-acetylglucosamine is added to the N-glycan precur...
A secretory vesicle containing primarily containing the phos...
A semi-synthetic form of the vitamin, cyanocobalamin (CNCbl,...
A series of receptor signaling pathways potentially govern c...
A series of sequential phosphorylation events lead to full o...
A short double-stranded RNA is passed from Dicer to an Argon...
A short double-stranded RNA is passed from Dicer to an Argon...
A simple example of epoxidation is the oxidation of an alken...
A single recent study indicates that HNF1-beta/vHNF/TCF2 is ...
A single recent study suggests that during embryonic pancrea...
A single unattached kinetochore is capable of preventing cel...
A small part of deacetylase activity required in the step pr...
A soluble form of PROCR (sEPCR) fully retains the ability to...
A specific transport process that exchanges 2-oxoglutarate f...
A study using cultured cells demonstrated connexon oligomeri...
A substantial fraction of rhodopsin kinase (GRK1) is bound t...
A substantial fraction of rhodopsin kinase (Grk1) is bound t...
A third mannose is added to the N-glycan precursor by ALG2 u...
A third mannose is added to the N-glycan precursor skeleton ...
A three dimensional crystal structure of NP suggests that th...
A typical mammalian egg is surrounded by an outer layer of a...
A variety of inhibitors capable of blocking the phosphoinosi...
A yeast mitochondrion contains about 1000 proteins, more tha...
A [4Fe-4S] cluster is assembled on a scaffold composed of th...
A [4Fe-4S] cluster is assembled on a scaffold composed of th...
A1CF protein is cytosolic in origin and is translocated to n...
A2b receptors (Peterfreund RA et al, 1996) are believed to p...
AADAT dimer localized in the mitochondrial matrix catalyzes ...
AADHAPR catalyzes the reaction of O-hexadecyldihydroxyaceton...
AARS (cytosolic alanyl tRNA synthetase) catalyzes the reacti...
AARS2 (mitochondrial alanyl tRNA synthetase) catalyzes the r...
Abacavir activation proceeds steps of phosphorylation, deami...
Abacavir is a nucleoside analogue reverse transcriptase inhi...
Abasic sugar phosphate removal via the single nucleotide rep...
ABCA1 associated with the plasma membrane binds extracellula...
ABCA3 plays an important role in the formation of pulmonary ...
ABCA7 has the ability to bind apolipoproteins and promote ef...
ABCC4 (Multidrug resistance protein 4 /MOAT-B) is a member o...
ABCG5/8 in the plasma membrane mediates the ATP-dependent ex...
Abelson interactor-1 (ABL) tyrosine kinase phosphorylates th...
Aberrant WNT signaling is associated with the development of...
Abl associated with Robo1, Slit2, and glypican at the plasma...
Abl binds directly, via its SH3 domain, to the CC3 motif in ...
ABL binds to the cytoplasmic tail of CDO and also to the p38...
Abl kinase phosphorylates the tyrosine residue (1073) of the...
Abl plays a dual role in the Robo pathway. As a key enzymati...
Abortive initiation, the repetitive formation of short oligo...
Abortive initiation, the repetitive formation of short oligo...
Abortive initiation, the repetitive formation of short oligo...
About 2-6% of all cytosine residues and 70-80% of cytosine r...
About 25 receptors are reported to couple to the G12/13 G pr...
Absence of alpha-L-iduronidase (IDUA, MIM:252800), the enzym...
Accumulated NF-kB-inducing kinase (NIK) activates I kappa-B ...
Accumulation of calcium into the Golgi apparatus is mediated...
Accumulation of monomethylated histone H4 (H4K20me1) is nece...
Accumulation of non-native or misfolded proteins upon cellul...
Accurate and efficient genome duplication requires coordinat...
ACER1 (alkaline ceramidase 1), associated with the endoplasm...
ACER1 (alkaline ceramidase 1), associated with the endoplasm...
ACER2 (alkaline ceramidase 2), associated with the membrane ...
ACER3 (alkaline ceramidase 3) catalyzes the hydrolysis of ph...
ACER3 (alkaline ceramidase 3) catalyzes the hydrolysis of ph...
Acetoacetate, beta-hydroxybutyrate, and acetone collectively...
Acetyl-CoA acetyltransferase tetramer (ACAT1) in the mitocho...
Acetyl-CoA acetyltransferase tetramer (ACAT1) in the mitocho...
Acetylated HSF1 was detected in lysates of human embryonic k...
Acetylated spermidine (NASPM) is oxidised by the flavoenzyme...
Acetylated spermine (NASPN) is oxidised by the flavoenzyme p...
Acetylation of RELA/p65 subunit differentially regulates dis...
Acetylation of the TAFI63 subunit of SL1 by PCAF stimulates ...
Acetylcholine binding activates postsynaptic acetylchloine r...
Acetylcholine is actively transported from the cytosol to th...
Acetylcholine neurotransmitter release cycle involves synthe...
Acetylcholine released by parasympathetic nerve endings in t...
Acetylcholine synaptic vesicle contains Rab3 ( GTPase), syna...
Acetylcholinesterase (ACHE) oligomers (comprising monomers, ...
Acetyltransferases ESCO1 and ESCO2 are homologs of the S. ce...
Acetyltransferases ESCO1 and ESCO2 are homologs of the S. ce...
Acid ceramidase (ASAH1) is a lysosomal enzyme that catalyses...
Acid-sensing ion channels 1, 2, 3 and 5 (ASIC1, 2, 3 and 5, ...
Acidification of the endosome does not continue further, and...
Acidification of the vesicle containing tetanus toxin disulf...
Acidification, a normal step in endocytosis causes a conform...
Acinus induces apoptotic chromatin condensation after cleava...
Acireducone (1,2-Dihydroxy-3-oxo-5'-methylthiopentene) is ox...
Acireductone synthase (also: enolase-phosphatase E1) catalyz...
Acquisition of DNA binding activity by HSF1 is necessary but...
Acrosin is localized in the acrosomal matrix as an enzymatic...
ACSS1 (acyl-CoA synthetase short-chain family member 1) in t...
Actin capping protein (CP) was named for its ability to bind...
Actin capping protein (CP) was named for its ability to bind...
Activated mammalian MEK1/2 is a serine/threonine kinase, wh...
Activated (phosphorylated) FADK1 acts as a scaffold and recr...
Activated (two-chain) urokinase plasminogen activator binds ...
Activated (two-chain) urokinase plasminogen activator binds ...
Activated adenylate cyclase associated with the plasma membr...
Activated adenylyl cyclase catalyzes the conversion of one m...
Activated AKT phosphorylates the BCL-2 family member BAD at ...
Activated AKT phosphorylates USP8, thereby stabilizing it an...
Activated AMPK (phosphorylated on the alpha subunit and with...
Activated AMPK (phosphorylated on Thr172 or Thr174 and AMP b...
Activated AMPK phosphorylates TSC2 and activates the TSC com...
Activated arylsulfatase A (ARSA) translocates to lysosomes b...
Activated BAX integrates in the outer mitochondrial membrane...
Activated by phosphorylation mixed lineage kinase domain-lik...
Activated CaMKIV phosphorylates CREB at S133 thereby initiat...
Activated CARD9 localised in lipid rafts may self-associate ...
Activated caspases cleave nuclear lamins causing the irreve...
Activated CDC42 (CDC42:GTP) can localize to kinetochores of ...
Activated CDC42 binds to Beta-Pix (p85Cool-1), a protein tha...
Activated CIT phosphorylates MRLCs (mysoin regulatory light ...
Activated citron kinase (CIT) binds KIF14 and PRC1 at the ce...
Activated DAAM1 recruits RHOA to the DVL complex in a WNT-de...
Activated epidermal growth factor receptors (EGFR) can stimu...
Activated ERKs (ERK1 i.e. MAPK3 and ERK2 i.e. MAPK1) phospho...
Activated factor XII (factor XIIa) binds to C1Inh (C1 inhibi...
Activated FMNL3 (presumably associated with RHOC:GTP) has th...
Activated human JNK kinases (MKK4 and MKK7) phosphorylate T...
Activated IKK complex phosphorylates the I-kappaB component ...
Activated intersectin 1 (ITSN1) activates CDC42 by exchangin...
Activated ISG15 linked to UBE1L is transferred to the E2 con...
Activated JAK2 binds to unphosphorylated STAT5; cytokine tre...
Activated JAK2 phosphorylates multiple tyrosine residues on ...
Activated JAKs are believed to be responsible for phosphoryl...
Activated JNK kinases (MKK4 and MKK7) phosphorylate threoni...
Activated kallikrein binds to alpha2-macroglobulin (Sottrup-...
Activated kallikrein binds to C1Inh (plasma protease C1 inhi...
Activated Mad2 upon release from kinetochores binds and sequ...
Activated MAP kinase-activated protein kinase (MAPK/MAPKAPK)...
Activated MAPK p38 alpha and beta phosphorylate KSRP at thre...
Activated MAPK/ERK activates RSK in its C terminal kinase do...
Activated MAPKAPK5 (PRAK) phosphorylates TP53 (p53) on serin...
Activated MEK phosphorylates and activates ERK.
Activated MEK1 phosphorylates and activates ERK1.
Activated MEK2 phosphorylates and activates ERK2.
Activated MEKK1 then phosphorylates and activates SAPK/Erk k...
Activated NLK phosphorylates TCF7L2 and LEF1 at serine and t...
Activated p21ras (the GTP-bound form) is associated with the...
Activated p38 alpha and beta phoshorylate Khsrp at threonine...
Activated p38 MAPK has been shown to phosphorylate and activ...
Activated PAK then phosphorylates a serene residue (S665) wi...
Activated PAK1 phosphorylates FLNA (filamin A) on serine res...
Activated PAR stimulates the G alpha (q) subunit to release ...
Activated PAR1 can induce the formation of signalling comple...
Activated PI3K bound to phosphorylated ERBB4 CYT-1 homodimer...
Activated PI3K complex directly bound to phosphorylated hete...
Activated PI3K phosphorylates phosphatidylinositol (PI) 4-ph...
Activated PI3K phosphorylates phosphatidylinositol (PI) 4-ph...
Activated PKA (protein kinase A) phosphorylates serine 36 of...
Activated PKA promotes the closing of inward rectifying pota...
Activated PKN1 (p-T774-PKN1) binds CDC25C (Isigawa et al. 20...
Activated PKN1 (p-T774-PKN1) phosphorylates CDC25C on serine...
Activated PKN1 (p-T774-PKN1) phosphorylates PPP1R14A (CPI-17...
Activated PKN1 binds androgen-activated AR (androgen recepto...
Activated PLA-gamma1 translocates to the plasmamembrane and ...
Activated PLC-gamma1 disassociates from LAT. Membrane bindin...
Activated PLCG translocates to the plasmamembrane and intera...
Activated PLK1 phosphorylates OPTN (optineurin) on serine re...
Activated point mutants in the transmembrane and kinase doma...
Activated protein C (APC) can either dissociate from PROCR t...
Activated Protein C (APC) is best known for its anticoagulan...
Activated protein C binds to Protein S on appropriate cell s...
Activated protein C cleaves peptide bonds in activated facto...
Activated Protein Kinase A phosphorylates Aquaporin-2 at Ser...
Activated Protein Kinase A promotes the release of calcium f...
Activated proto-oncogene vav (VAV) act as guanine nucleotide...
Activated RAC1 (RAC1:GTP) binds NADPH oxidase NOX1 complex c...
Activated RAC1 (RAC1:GTP) binds to the NADPH oxidase NOX3 co...
Activated Rac1 binds to and stimulates the kinase activity o...
Activated Rac1 bound to plexin-A might modulate actin dynami...
Activated rat HSL at the lipid particle hydrolyzes triacylgl...
Activated rat HSL hydrolyzes cholesterol ester to yield chol...
Activated RHO GTPase RHOQ (TC10) regulates the trafficking o...
Activated RHOA (RHOA:GTP) binds rhophilin-1 (RHPN1) or rophi...
Activated RHOB (RHOB:GTP) recruits DIAPH1 or DIAPH3 to endos...
Activated RHOD (RHOD:GTP) binds DIAPH2 transcription isoform...
Activated rhodopsin (MII aka R*) must be deactivated to term...
Activated ROCK directly phosphorylates FAK1 on S732. This ph...
Activated SRC binds STAT3. v-Src was shown to bind and phosp...
Activated Syk (or possibly the related kinase Lck) phosphory...
Activated thrombin (factor IIa) binds to thrombomodulin at t...
Activated thrombin (factor IIa) catalyzes the conversion of ...
Activated thrombin binds to the antithrombin III:heparin com...
Activated thrombin cleaves the A chains of factor XIII tetra...
Activated TrkA induces the tyrosine phosphorylation of the l...
Activated type I receptor kinase directly phosphorylates two...
Activated ubiquitin is transferred from E1 to the active sit...
Activated VAV2/3 act as guanine nucleotide exchange factors ...
Activating mutations in FGFR3 that introduce a mutant cystei...
Activating point mutations G380R, N540K and K650E/M/N/Q in F...
Activating point mutations in FGFR3 are found in the extrace...
Activation of a subset of FGFR1-fusions (ZMYM2, BCR, FGFR1OP...
Activation of ATM kinase in response to DNA damage in the fo...
Activation of Calcium-release-activated (CRAC) channels allo...
Activation of classical Kir (K+ inwardly rectifying) channel...
Activation of eIF2 through direct binding of GTP. ...
Activation of EPH receptors triggers the local activation of...
Activation of EPHAs leads to phosphorylation of ephexin1 (NG...
Activation of ephrin-B1 (EFNB1) and ephrin-B2 (EFNB2) by pos...
Activation of Erk1/2 downstream of FGFR mutants suggests tha...
Activation of FACTOR VII expression by phosphorylated BMAL1:...
Activation of FGFR mutants has in some cases been shown to r...
Activation of Kir 3 channels occurs after binding of G beta ...
Activation of KIT mediates the recruitment of and associatio...
Activation of lectin pathway begins when mannan-binding lect...
Activation of NF-kB signaling is a critical event downstream...
Activation of non- excitable cells involves the agonist-indu...
Activation of NR1D1 (REV-ERBA) expression by phosphorylated ...
Activation of PAK-2p34 coincides with autophosphorylation of...
Activation of phospholipase C enzymes results in the generat...
Activation of phospholipases releases free arachidonic acid ...
Activation of PLCG1 signaling is observed only in the presen...
Activation of PPARG transcription by CEPBA is inferred from ...
Activation of SMO downstream of Hh ligand binding results in...
Activation of SMO in vertebrate cells depends upon its seque...
Activation of Src kinases involves displacement of Tyr527 fr...
Activation of Src lies selectively downstream of P2Y1, but n...
Activation of SYK triggers multiple cascades, which induces ...
Activation of SYK triggers multiple cascades, which induces ...
Activation of the Hh pathway causes the GLI:SUFU complex to ...
Activation of the mitotic cyclin:Cdc2 complexes at mitosis r...
Activation of the mitotic cyclin:Cdc2 complexes at mitosis r...
Activation of the novel Protein Kinase C (nPKC) isoforms (de...
Activation of the PI3K pathway has been demonstrated downstr...
Activation of the PI3K pathway has been demonstrated in the ...
Activation of the PI3K signaling pathway has been demonstrat...
Activation of the transmembrane protein SMO in response to H...
Activation of TRKA by NGF triggers STAT3 phosphorylation at ...
Activation of tumor necrosis factor receptor 1 (TNFR1) can t...
Activation of TWIK channels results in low outward K+ curre...
Activation of VEGFR2 has been shown to lead to direct bindin...
Activation of VEGFR2 results in the activation of phosphatid...
Activation of voltage gated potassium channel is triggered b...
Activator protein-1 (AP-1) is a collective term referring to...
Active caspase 8 associates with the membranes during apopto...
Active caspase-3 is translocated from the cytoplasm to the n...
Active Cyclin A:Cdk2 complexes phosphorylate and inactivate ...
Active Gt alpha (GNAT-GTP) can be inactivated by a slow, int...
Active PI3K in complex with p-EGFR:p-ERBB2:GRB2:GAB1 phospho...
Active PI3K in complex with phosphorylated ERBB2:ERBB4cyt1 h...
Active PKG homodimers restrict Ca2+ release in the absence o...
Active Rac1 associates directly with Plexin-A1 in the linker...
Active Raf-1 phosphorylates MEK-1/2 on Serine residues, conv...
Active Rap1 binds but does not activate Raf-1, preventing Ra...
Active steroid hormones are produced from the precursor chol...
Activin B or Activin AB, but not Activin A binds Activin rec...
Activin binds the Activin receptor composed of a type II rec...
Activin receptors containing the type II receptors ACVR2A/B ...
Activin was initially discovered as an activator of follicle...
Acyl chain remodeling of cardiolipin (CL) occurs in the inne...
Acyl chain remodeling of triacylglycerol (TAG) and diacylgly...
Acyl ghrelin and C-ghrelin are secreted from secretory granu...
Acyl proghrelin is cleaved by prohormone convertase 1/3 (PC1...
Acyl-CoA synthetase long-chain family member 4 (ACSL4) assoc...
Adam10 knockout mice have impaired development of the margin...
ADAM8 can cleave fibronectin in human cartilage extracts at ...
ADAP (FYB) is an adaptor protein containing multiple binding...
Adapter proteins GADS, GRAP, GRB7 and GRB10 interact with ac...
Adaptive immunity refers to antigen-specific immune response...
Addition of a fucose moiety as an alpha 1-6 linkage to the f...
Addition of a galactose residue on N-acetylglucosamine. The ...
Addition of sialic acid (Neu5Ac) to galactose-containing N-g...
Addition of sialic acid (Neu5Ac) to galactose-containing N-g...
Addition of sialic acid to galactose-containing N-glycan. Si...
Adenosine, acting through A2A receptors can induce TrkA acti...
Adenosylhomocysteinase (AHCY) is a tetrameric, NAD+-bound, c...
Adenosylhomocysteinase (AHCY) is a tetrameric, NAD+-bound, c...
Adenosylhomocysteinase (AHCY) is a tetrameric, NAD+-bound, c...
Adenoviral expression of the BAP31 cleavage product, p20 cau...
Adenylate cyclase catalyses the synthesis of cyclic AMP (cAM...
Adenylate cyclase is responsive to calcium and calmodulin an...
Adenylyl cyclases V and VI are the particular adenylyl cycla...
ADHFE1 catalyzes the reversible reaction of (R)-2-hydroxyglu...
ADHFE1 catalyzes the reversible reaction of 2-oxoglutarate a...
Adipogenesis is the process of cell differentiation by which...
Adjacent cisternae of the Golgi apparatus are stacked and li...
ADP activates human platelets and induces endothelial cell m...
ADP is the most important constituent of dense granules, ess...
ADP-ribosylation factor-like protein 2 (ARL2) is a small (2...
ADRBK1 phosphorylates the SMO C-terminal tail after initial ...
Adrbk1 phosphorylates the Smo C-terminal tail in the S1 to S...
Adrenaline (epinephrine) signalling via the alpha-2 adrenerg...
Adrenocorticotropic hormone (ACTH, POMC(138-176)) stimulates...
Advanced glycosylation end product specific receptor (AGER) ...
Advanced Glycosylation End- product-specific Receptor (AGER)...
AES is a naturally occuring truncated form of TLE that conta...
Aes is a naturally occuring truncated version of Groucho/TLE...
Afadin serves as a linker of the actin cytoskeleton to the p...
Aflatoxin B1 (AFB1) requires microsomal oxidation to produce...
Aflatoxin B1 (AFB1) requires microsomal oxidation to produce...
Aflatoxin B1 (AFB1) undergoes extensive oxidation, which is ...
Aflatoxin B1 (AFB1), a category I known human carcinogen and...
Aflatoxin B1 aldehyde reductases (AKR7A2, AKR7A3 and AKR7L) ...
Aflatoxin B1-8,9-dihydrodiol (AFBDHD) undergoes base-catalys...
Aflatoxins are among the principal mycotoxins produced as se...
Aflatoxins are produced by the fungal molds Aspergillus flav...
After abasic (AP) residue (5'dRP) is excised by POLB, which ...
After aberrantly dimerizing in response to epithelially expr...
After aberrantly dimerizing in response to mesenchymally exp...
After about 15 minutes on the cell surface, the equilibrium ...
After activation, FGFR mutants are presumed to recruit FRS2 ...
After APC/C-mediated degradation of PTTG1 (securin), ESPL1 (...
After assembly of the complete RNA polymerase II-preinitiati...
After autophosphorylation the type 1 insulin-like growth fac...
After being activated by a mismatch, MSH2:MSH6 (MutSalpha) r...
After being activated by an insertion/deletion loop (IDL), M...
After being bound by BetaKlotho and FGF19, FGFR4 undergoes a...
After being phosphorylated by GSK3beta on the PPPSP motifs, ...
After being phosphorylated, p-ERK1/2 dissociate from MEK1/2 ...
After being recruited into the NIK (NFkB-inducing kinase) co...
After being synthesized in the ER membrane the 14-sugars lip...
After being ubiquitinated, the bulk of GLI2 is fully degrade...
After binding a mismatch, the MSH2:MSH3 (MutSbeta) heterodim...
After binding a mismatch, the MSH2:MSH6 (MutSalpha) heterodi...
After binding BCL10, MALT1 also undergoes oligomerization. L...
After binding ERBB4 homodimers, SHC1 gets phosphorylated on ...
After binding Piwil1 (Miwi in mouse, HIWI in human) the 3' e...
After binding Piwil2 (Mili in mouse, HILI in human) the 3' e...
After binding the FZD receptor, the G-protein alpha subunit ...
After binding to OS9/ERLEC1, the Hh C-terminal fragments are...
After cleavage by PLD6 at the 5' end, the pre-piRNA is bound...
After cleavage by Pld6 at the 5' end, the pre-piRNA is bound...
After cleavage by Pld6 at the 5' end, the pre-piRNA is bound...
After cleavage by PLD6 at the 5' end, the pre-piRNA is bound...
After cleavage of C5, C5b undergoes conformational changes a...
After cleaving DNA Spo11 remains covalently attached to the ...
After CLEC7A (dectin-1) triggering, MALT1 and caspase-8 asso...
After cross linking, Fc gamma receptors are sequestered to l...
After deadenylation, mRNAs have 10-15 3' adenosine residues ...
After dephosphorylation by PPM1A, SMAD2 and SMAD3 translocat...
After dimerization of the PDGF-A and PDGF-B chains in the ER...
After dimerization STAT dimers release from the receptor com...
After DNA damage is bypassed by error-prone DNA polymerases ...
After docking at the membrane VAMP2 on the vesicle interacts...
After docking at the membrane Vamp2 on the vesicle interacts...
After ERBB4 is cleaved by ADAM17, gamma-secretase complex pe...
After forming a complex in the nucleus, SMAD7:SMURF2 traffic...
After forming in the cytoplasm, the Cyclin A:Cdk2 complexes ...
After fusion of the viral membrane with the target cell memb...
After high-affinity ligand binding, FGFR3 P250R is believed ...
After holocarboxylase degradation, biocytin (BCTN) transloca...
After incision of the DNA strand 5' to the apurinic/apyrimid...
After incorporating two dAMPs opposite the thymine-thymine c...
After incorporation at the branch, the actin bound to VCA do...
After initial phosphorylation by SFK's, subsequently Y223 (Y...
After interaction with its ligand HLA-E, which is expressed ...
After internalization, F-actin is depolymerized from the pha...
After it incorporates a dNMP opposite to a damaged template ...
After juxtaposition of the luminal N-termini of IRE1 to form...
After ligand-independent dimerization, FGFR1 fusions are tra...
After NGF binding, activated Trk receptors provide multiple ...
After NOTCH1 coactivator complex is assembled on a NOTCH-tar...
After NOTCH1 PEST domain mutants bind a DLL (DLL1 or DLL4) o...
After nucleotide exchange, the G-protein alpha subunit disso...
After NUMB:ITCH-mediated ubiquitination, GLI1 is degraded by...
After passing through the Golgi complex, secretory cargo is ...
After phosphorylated SMAD2 and/or SMAD3 form a heterotrimer ...
After phosphorylated SMAD2/3 accumulate in the nucleus in re...
After phosphorylating the SMO dimer, CSNK1A1 and ADRBK1 pres...
After phosphorylation and ubiquitination, GLI3 is processed ...
After phosphorylation by PDK1, PKC undergoes autophosphoryla...
After phosphorylation on Thr 508, LIMK undergoes homodimeriz...
After phosphorylation Stat5a and Stat5b form homodimers and ...
After Platelet activation '78 kDa glucose-regulated protein'...
After Platelet activation 'Calumenin' from the endoplasmic r...
After Platelet activation 'Proactivator polypeptide' from th...
After Pol II pauses by back tracking 2 -4 nuleotides on the ...
After POLB (DNA polymerase beta) fills a single nucleotide g...
After POLB (DNA polymerase beta) fills the single nucleotide...
After pre-RC assembly and Cdc45 association with the origin ...
After processing by the proteasome, some of the oligopeptide...
After processing by the proteasome, the truncated GLI3 trans...
After proteolytic activation, tBID is myristoylated by NMT-1...
After recruiting IRAK, MYD88 leaves the receptor complex. Th...
After recruitment to activated FGFR mutants, FRS2 is believe...
After removal of the N- and C-procollagen propeptides, fibri...
After removal of the N-terminal methionine (Met) residue, an...
After removal of the N-terminal methionine (Met) residue, th...
After retrotranslocation to the cytosol, Hh-C is degraded by...
After retrotranslocation to the cytosol, processing-defectiv...
After REV1 inserts a nucleotide directly opposite the templa...
After RFC initiates the assembly of the primer recognition c...
After RPA binds the long flap, it recruits the Dna2 endonucl...
After secretion Cathepsin G is extracellular and associated ...
After secretion Cathepsin Z (Cathepsin X) is extracellular a...
After serine was transferred onto its sulfhydryl group, a me...
After SMAD7:SMURF1 complex binds to XPO1 (CRM1) through the ...
After SMURF-dependent ubiquitination, PTCH1 is internalized ...
After stimulation by WNT3A, FZD5 and phosphorylated LRP6 are...
After TGF-beta stimulation, TGFBR2 binds TGFBR1 anchored to ...
After the initiation of DNA condensation during mitosis, Nu...
After the acrosome reactome the sperm has passed through the...
After the assembly of the RNA Polymerase I Holoenzyme, Rrn3 ...
After the base excision repair is completed, the complex of ...
After the capping complex is formed, the RNA triphosphatase ...
After the cleaved RNA binds PIWIL2 (HILI in human, homolog o...
After the cleaved RNA binds Piwil2 (Mili) the 3' end is trim...
After the cleaved RNA binds PIWIL4 the 3' end is trimmed by ...
After the cleaved RNA binds Piwil4 the 3' end is trimmed by ...
After the completion of the base excision repair (BER), NEIL...
After the Cyclin D serves the role of mediating reactions by...
After the fusion of phagosome and lysosome lumen acidity ris...
After the generation of PIP3 by PI3K, a part of it is furthe...
After the glycosylated precursor is attached to the protein,...
After the initial adhesion, the EPH- and ephrin (EFN)-bearin...
After the initial cleavage of the N-terminus, MMP3 undergoes...
After the lipid-linked oligosaccharide (LLO) precursor is at...
After the lipid-linked oligosaccharide (LLO) precursor is at...
After the MOCS2A dimer is loaded with two sulfur atoms, thei...
After the nascent pre-mRNA undergoes the initial capping and...
After the PCNA-dependent long patch base excision (BER) is c...
After the phosphorylation and activation CARMA1 undergoes ol...
After the POLB-dependent long patch base excision (BER) is c...
After the primers are synthesized on the G-Rich strand, Repl...
After the primers are synthesized, Replication Factor C bind...
After the second jump, elongation of the plus and minus stra...
After the transport of the glycoprotein to the cis-Golgi, th...
After the very fast isomerisation of the 11-cis-retinyl (11c...
After the virus binds to the target cell surface and is endo...
After transcription, some RNA molecules are altered to conta...
After transiting to the nucleus SREBPs (SREBP1A/1C/2, SREBFs...
After translation, many newly formed proteins undergo furthe...
After translation, many newly formed proteins undergo furthe...
After translocation into the nucleus, AKT can phosphorylate ...
After ubiquitinating PTCH1, the SMURF E3 ligase presumably d...
After ubiquitinating TLE, XIAP presumably dissociates. The ...
After ubiquitination by HECW1, DVL1 is degraded by the prote...
After ubiquitination by RNF111 (Arkadia), ubiquitinated SMAD...
After ubiquitination by SMURF2, AXIN is degraded by the prot...
After ubiquitination, CBL dissociates from SPRY2
After undergoing rounds of translation, mRNA is normally de...
Aggrecan (large aggregating proteoglycan, chondroitin sulfat...
Aggrecan (large aggregating proteoglycan, chondroitin sulfat...
Aggrecan (large aggregating proteoglycan, chondroitin sulfat...
Agmatine is an amine that is formed by decarboxylation of L-...
Agmatine is polyamine formed by decarboxylation of L-arginin...
Agrin (AGRN) is a >400 kDa multi-domain heparan sulfate prot...
Agrin (AGRN) is a large (>400 kDa) multi-domain heparan sulf...
Agrin (AGRN) is a large multidomain heparan sulfate proteogl...
Agrin (AGRN) is a multidomain heparan sulfate proteoglycan f...
Agrin binds a complex of the tyrosine kinase receptor MuSK, ...
Agrin is a large (>400 kDa) heparan sulfate proteoglycan fou...
Agrin is a large (>400 kDa) multi-domain heparan sulfate pro...
Agrin, a Heparin Sulfate Proteoglycan (HSPG), plays a role i...
AhpC is an unusual peroxiredoxin - it has three cysteine res...
AIM2 binds to cytosolic dsDNA via its C-terminal HIN domain....
AIM2 is a member of the PYHIN or HIN200 family. It has a C-t...
AIM2 oligomerizes, forming AIM2 clusters that are able to in...
AJUBA, a LIM domain-containing protein, binds centrosome-ass...
AKT can phosphorylate the apoptotic protease caspase-9, inhi...
AKT inhibitors bind AKT and prevent its association with the...
AKT inhibits DNA binding of NUR77 and inhibits its pro-apopt...
AKT mediates IKKalpha (Inhibitor of nuclear factor kappa B k...
AKT phosphorylates and inhibits TSC2 (tuberin), a suppressor...
AKT phosphorylates CREB (cAMP response element-binding prote...
AKT phosphorylates MDM2 on two serine residues, at positions...
AKT, phosphorylated at threonine (AKT1 308; AKT2 309; AKT3 3...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to phosphoryla...
AKT1 E17K gain-of-function mutant is expected to translocate...
AKT1 E17K gain-of-function mutant phosphorylates BAD (Guo et...
AKT1 E17K gain-of-function mutant phosphorylates FOXO3 (Carp...
AKT1 E17K gain-of-function mutant preserves the ability to p...
AKT1 E17K gain-of-function mutant preserves the ability to p...
AKT1 is recruited to the M domain of HSP90.
Akt2 (Pkb-beta) phosphorylates Rbc2 (Ralgapa2) on serine-486...
Akt2 and, to a lesser extent, Akt1 phosphorylate As160 (Tbc1...
Alanine-glyoxylate transaminase (AGXT) catalyzes the irrever...
ALAS2 protein is synthesized at high levels in erythroid pre...
Aldehyde oxidase (AOX1) is a complex molybdo-flavoprotein th...
ALDH1A1 (aldehyde dehydrogenase) in the cytosol catalyzes th...
ALDH2 (aldehyde dehydrogenase) in the mitochondrial matrix c...
Aldo-keto reductase family 1 member C3 (AKR1C3) aka PGFS is ...
Aldo-keto reductase family 1 member C3 (AKR1C3) aka PGFS is ...
Aldosterone, the major human mineralocorticoid, is synthesiz...
Alignment of the C-terminal prodomains initiates triple heli...
AlkB is an E.coli alpha-ketoglutarate- and Fe(II)-dependent ...
ALKBH2 binds alkylated DNA containing 1-ethyladenine (1-etA)...
ALKBH2 binds alkylated DNA containing 1-methyladenine (1-meA...
ALKBH2 binds alkylated DNA containing 3-methylcytosine (3-me...
ALKBH2 catalyzes removal of the ethyl group from 1-ethyladen...
ALKBH2 catalyzes removal of the methyl group from 3-methylcy...
ALKBH2 catalyzes the removal of the methyl group from 1-meth...
ALKBH3 (ABH3) has a preference for binding single strand DNA...
ALKBH3 (ABH3) has a preference for binding single strand DNA...
ALKBH3 (ABH3) has a preference for binding single strand DNA...
ALKBH3, a homolog of E.coli AlkB (Trewick et al. 2002), remo...
ALKBH3, a homolog of E.coli AlkB (Trewick et al. 2002), remo...
ALKBH3, a homolog of E.coli AlkB (Trewick et al. 2002), remo...
ALKBH3, like ALKBH2, is a homolog of E.coli alpha-ketoglutar...
All characterised lysine demethylases other than KDM1A belon...
All characterized lysine demethylases other than KDM1A belon...
All characterized lysine demethylases other than KDM1A belon...
All characterized lysine demethylases other than KDM1A belon...
All characterized lysine demethylases other than KDM1A belon...
All CLCAs contain a consensus cleavage motif which is recogn...
All ERBB2 heterodimers, ERBB2:EGFR, ERBB2:ERBB3 and ERBB2:ER...
All eukaryotic proteins synthesized in the cytosol are initi...
All four vertebrate TCF/LEF proteins have been demonstrated ...
All functionally characterized TRP channels are permeable to...
All kinesins contain a motor domain or head, the position va...
All known myosin phosphatases consist of PP1 beta and both a...
All mammals have three fibrillin genes (Davis & Summers 2012...
All neurotrophins (NTs) are generated as pre-pro-neurotrophi...
All of the key components and regulators of the COPI coat (G...
All organisms are constantly exposed to foreign chemicals ev...
All RNA polymerases III terminate transcription at extremely...
All splicing isoforms of ERBB4 possess two tyrosine residues...
All the newly synthesized PDGF chains are dimerized in the E...
All three ERBB4 isoforms are activated by binding of neuregu...
All TLRs, except for TLR3, employ the MyD88-dependent signal...
All WNT ligands are predicted to be highly glycosylated. By...
All WNT proteins except Drosophila WntD are lipid modified. ...
All-trans-retinal (atRAL) can diffuse across membranes to th...
All-trans-retinoic acid (atRA) is a biologically activated ...
All-trans-retinoic acid (atRA) metabolism can be mediated by...
All-trans-retinol (atROL) binds to cellular retinol-binding ...
All-trans-retinol (atROL) circulates in the bloodstream in c...
All-trans-retinol (atROL) is stored in hepatic stellate cell...
All-trans-retinol (atROL), the product of the reduction of a...
All-trans-retinol esters (atREs) serve as substrates for ret...
All-trans-retinyl esters (atREs) are the main storage form o...
Allysine residues can condense with lysine residues forming ...
Allysine residues condense with hydroxylysine residues to fo...
Almost concomitantly a second effect resulting from the tyro...
Alpha 1,3/1,6 mannosyltransferase ALG2 (ALG2) is a bifunctio...
Alpha 1,3/1,6 mannosyltransferase ALG2 (ALG2) is a bifunctio...
Alpha 2-macroglobulin (A2M) is a plasma glycoprotein consist...
Alpha and beta tubulin folding intermediates are formed thro...
Alpha defensins HNP1-4, the neutrophil defensins, are stored...
Alpha granules contain mainly polypeptides such as fibrinoge...
Alpha v beta 3 integrin is one of the potential heterophilic...
alpha,beta-elimination activity of cystathionine-gamma-lyase...
Alpha-1,2-mannosyltransferase ALG9 (ALG9) normally catalyses...
Alpha-1,2-mannosyltransferase ALG9 (ALG9) normally catalyses...
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminylt...
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminylt...
Alpha-1-Microglobulin binds heme b (Allhorn et al. 2002, Lar...
Alpha-2 adrenoceptors couple with G protein alpha-i subtype ...
Alpha-adducin (ADD1 aka ADDA) (Joshi et al. 1991) is a ubiqu...
Alpha-adducin (ADD1 aka ADDA) (Joshi et al. 1991) is a ubiqu...
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) catal...
Alpha-defensins, theta-defensins and their synthetic analogu...
Alpha-defensins, theta-defensins and their synthetic analogu...
Alpha-dystroglycan (DG) binds G domain-like sequences in oth...
Alpha-dystroglycan binds G domain-like sequences in other ex...
Alpha-galactosidase A (GLA) (Bishop et al. 1986) removes the...
Alpha-linolenic acid (ALA, 18:3(n-3)) is an omega-3 fatty ac...
Alpha-linoloyl-CoA is converted to Stearidonoyl-CoA (SDA, 6,...
Alpha-N-acetylglucosaminidase (NAGLU) also hydrolyses anothe...
Alpha-N-acetylglucosaminidase (NAGLU) also hydrolyses anothe...
Alpha-N-acetylglucosaminidase (NAGLU) hydrolyses the non-red...
alpha-secretase (ADAM17) is a metalloprotese that has the ab...
Alpha5beta1 integrin was the first integrin shown to bind fi...
also Apert
Alterations in AXIN1 have been detected in a number of diffe...
Alternately dopamine is metabolized to homovanillic acid in ...
Alternatively, the EPH:ephrin (EPH:EFN) interaction can be b...
Although a direct interaction between IPAF and an activating...
Although a role for SHC1 in FGF signalling has been implicat...
Although ATM is dispensable for Chk1 phosphorylation, caffei...
Although direct phosphorylation of GLI1 by PKA has not been ...
Although each of FGFR3 R248C, S249C, G370C, S371C and Y373C ...
Although interphotoreceptor retinoid-binding protein (RBP3, ...
Although IRAK-1 was originally thought to be a key mediator ...
Although it has not been rigourously established, there is s...
Although it is well established that stabilized beta-catenin...
Although JAM-C is better known for its interaction with MAC-...
Although ligand-responsive EGFR mutants dimerize spontaneous...
Although mycothiol is able to conjugate by itself with elect...
Although NEIL1 and NEIL2 have a weak 8-oxoguanine glycosylas...
Although neuropilin-1 is required for Sema-3A action, it is ...
Although phosphorylation of activated rhodopsin (MII) reduce...
Although phosphorylation of activated rhodopsin (MII) reduce...
Although RLR-mediated signaling to NFkB and MAPK shares simi...
Although TBP (TATA box binding factor) is necessary and suff...
Although the mechanism through which L13a prevents transl...
Although the enzyme catalysing retinal reduction in human en...
Although the role of retromer in delivering WLS back to the ...
Although there is no direct evidence for CysE catalyzing the...
Although, DNA replication occurs in the S phase of the cell ...
Alveolar macrophages normally develop their phagosome along ...
Aly/Ref recruits TAP to the Exon Junction Complex. This make...
AMER1 was identified as a gene mutated in a subset of Wilms ...
AMER1/WTX is a component of the destruction complex that int...
AMER1/WTX is a known component of the destruction complex an...
Amiloride-sensitive sodium channels (SCNNs, aka ENaCs, epith...
Amiloride-sensitive sodium channels (SCNNs, aka ENaCs, epith...
Amine oxidase (flavin-containing) A (MAOA) catalyses the oxi...
Amine oxidase (flavin-containing) A (MAOA) catalyses the oxi...
Amine oxidase (flavin-containing) A (MAOA) catalyses the oxi...
Amino acid transport across plasma membranes is critical to ...
Aminoacylase 1 (ACY1) is a cytosolic, homodimeric zinc-bindi...
Aminopeptidase A (APA, ENPEP) hydrolyzes the N-terminal amin...
Aminopeptidase N (APN, ANPEP, aminopeptidase M, alanyl amino...
Among netrin1 receptors neogenin is the only protein to inte...
Among the seven members of the Stat family, Stat1, Stat3, St...
AMOT (130 KDa isoform) and AMOTL1 can each bind WWTR1 (TAZ) ...
AMOT (130 KDa isoform), AMOTL1, and AMOTL2 can each bind YAP...
AMP (adenosine monophosphate) is synthesized in two steps fr...
AMP-activated protein kinase (AMPK) is a sensor of cellular ...
AMPA receptors are functionally either Ca permeable or Ca im...
AMPA receptors bind glutamate, released in the synaptic clef...
AMPK is activated by AMP and phosphorylates Pgc-1alpha (Ppar...
Ampk-alpha2 phosphorylates Tbc1d1 on serine-231 and probably...
Amplification of full length FGFR2 is only weakly transformi...
Amplification or activation of FGFR1 has been reported in l...
Amplified FGFR2 has been shown to be a potential target for ...
Amylin (islet amyloid polypeptide, diabetes associated pepti...
Amyloid fibril formation is associated with a wide range of ...
Amyloid is a term used to describe typically extracellular d...
An active Pol II complex consisting mainly of the Pol II hol...
An aldehyde dehydrogenase (ALDH) yet to be cloned in humans ...
An array of inositol trisphosphate (IP3) and tetrakisphospha...
An array of kinases catalyze the reversible phosphorylation ...
An as-yet-uncharacterised protein has been demonstrated to p...
An extracellular spherical HDL particle binds to the plasma ...
An important function of the kinase cascade triggered by neu...
An intermediate region located between the CARD and kinase d...
An L-iduronic acid residue can be cleaved from either hepara...
An N-acetylgalactosamine (GalNAc) moiety is added to the cho...
An unidentified protein tyrosine kinase located in the plasm...
An unknown cysteine-S-conjugate N-acetyltransferase (NAT) ca...
An unknown galactosyltransferase mediates the transfer of ga...
An unknown N-acetylgalactosaminyltransferase mediates the tr...
An unknown N-acetylglucosaminyltransferase mediates the tran...
An unknown N-acetylglucosaminyltransferase mediates the tran...
An unusual characteristic of the influenza virus life cycle ...
Analogous to arachidonate 5-lipoxygenase (ALOX5) biosynthesi...
Analogous to prostaglandin E2 (PGE2), dehydration of the pro...
Analysis of a structural model of the Leptin-LEPR complex us...
Anaphylatoxic peptides C3a and C5a function as mediators of ...
Anchoring fibrils are structures in skin that consist largel...
Androgens are the determining factors for male development a...
Ang4 represents a third protein of the Ang family that binds...
Angiogenesis is the formation of new blood vessels from pree...
Angiotensin-converting enzyme (ACE) hydrolyzes angiotensin-(...
Angiotensin-converting enzyme (ACE) hydrolyzes angiotensin-(...
Angiotensin-converting enzyme 2 (ACE2) hydrolyzes angiotensi...
Angiotensin-converting enzyme 2 (ACE2) hydrolyzes angiotensi...
Angiotensinogen, a prohormone, is synthesized and secreted m...
Animals cannot synthesize pyridoxal 5'-phosphate (PLP) which...
ANKLE2 (LEM4) is required for nuclear envelope formation in ...
Ankyrin-Rich Membrane Spanning protein (ARMS or Kidins220) i...
Ankyrins are a family of adaptor proteins that couple membra...
Ankyrins are bifunctional linker proteins that tether L1 to ...
Ankyrins link both L1 and ion channel proteins, coupling the...
Another important antioxidant activity is the KatG catalase/...
Another member of the short-chain dehydrogenases/reductases ...
Another outer surface membrane-bound, homodimeric enzyme, di...
ANPEP from rabbit renal membranes hydrolyzes angiotensin III...
Anterograde trains travel along the axoneme of the primary c...
Anthrax EF (edema factor) and LF (lethal factor) toxins boun...
Anthrax EF (edema factor) and LF (lethal factor) toxins boun...
Anthrax LF (lethal factor) a zinc metalloprotease (Klimpel e...
Anthrax LF (lethal factor) a zinc metalloprotease (Klimpel e...
Anthrax LF (lethal factor) a zinc metalloprotease (Klimpel e...
Anthrax LF (lethal factor) a zinc metalloprotease (Klimpel e...
Anthrax LF (lethal factor) a zinc metalloprotease (Klimpel e...
Anthrax LF (lethal factor), a zinc metalloprotease (Klimpel ...
Antifungal immunity through the induction of T-helper 17 cel...
Antigen presenting cells (APCs) such as B cells, dendritic c...
Antigen processing and loading on to MHC class II molecules ...
Antigen receptor triggered PKC theta dependent linker phosph...
Antiparallel NCAM interactions involve trans-interactions of...
Antithrombin III binds to membrane-associated heparin, e.g.,...
Antithrombin III in the complex is cleaved by thrombin, ther...
Antiviral responses must be tightly regulated in order to pr...
Antizyme inhibitor blocks the effects of antizyme on ODC. It...
Antizyme is a non-competitive inhibitor of ODC that is synth...
ANTXR1 (Anthrax Receptor 1)-bound PA63 (protective antigen, ...
ANTXR2 (Anthrax Receptor 2)-bound PA63 (protective antigen, ...
any remaining instances associated here should be reassociat...
AP-1 complex subunit gamma-like 2 (AP1G2) is an 87-kDa prote...
AP-2 is recruited to the newly formed Nef:CD4 complex
AP-4 complex subunit mu-1 (AP4M1) can recognise and interact...
Apaf-1 and Caspase-9 form a complex in the presence of dATP ...
Apart from its well-established interaction with Integrin al...
APC has been shown to be reversibly modified with K63-linked...
APC is a large and central component of the destruction comp...
APC is K63 polyubiquitinated in the absence of WNT signal an...
APC is phosphorylated on the 20 aa repeats by CK1 and potent...
APC/C:Cdc20 is first activated at the prometaphase/metaphase...
APC:CDC20 mediates the degradation of a number of cell cycle...
Apelin (Tatemoto K et al, 1998) is an endogenous ligand for ...
Apert sydrome is the most severe of the craniosynostosis syn...
APEX1 (APE1) bound to oxidatively damaged 5' AP (apurinic/ap...
APEX1 (APE1) bound to the apurinic/apyrimidinic site (AP sit...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site DN...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site ly...
APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic site lyase, ...
ApoA-I bound to CUBN:AMN on the cell surface is endocytosed,...
APOBEC-1 binds to ACF:stem-looped mRNA complex forming the e...
APOBEC3G is incorporated into virus particles through its as...
APOBEC3G is multi-ubiquitinated by the Vif-Cul5-SCF complex.
Apoliprotein M (APOM) is a plasma protein usually associated...
Apoptosis induced caspases cleave cortical actin network com...
Apoptosis is a distinct form of cell death that is functiona...
Apoptosis-induced cleavage of beta-catenin by caspase 3 res...
Apoptotic cell death is achieved by the caspase-mediated cl...
Apoptotic cells show dramatic rearrangements of tight junct...
Apoptotic factors released from the mitochondria promote apo...
Approximately a quarter of the 57 human CYPs still remain "o...
Approximately half of circulating GH is bound to Growth Horm...
APS adapter protein has been identified as a KIT binding par...
APS bound to KIT is phosphorylated by tyrosine kinases in re...
Aquaporin-0 (AQP0, also known as MIP), AQP1, AQP2, AQP3, AQP...
Aquaporin-1 (AQP1) passively transports carbon dioxide (CO2)...
Aquaporin-1 (AQP1) passively transports water across the pla...
Aquaporin-2 (AQP2) passively transports water across membran...
Aquaporin-3 (AQP3) passively transports water and glycerol a...
Aquaporin-3 (AQP3), AQP7, AQP9, and AQP10 are 6-pass transme...
Aquaporin-4 (AQP4) passively transports water across the pla...
Aquaporin-6 (AQP6) passively transports anions across membra...
Aquaporin-7 (AQP7) passively transports glycerol and water a...
Aquaporin-9 (AQP9) and AQP10 are 6-pass transmembrane protei...
Aquaporin-9 (AQP9) passively transports water, glycerol, ure...
Aquaporins (AQP's) are six-pass transmembrane proteins that ...
Arachidonate 12-lipoxygenase, 12S-type (ALOX12) (Funk et al....
Arachidonate 12-lipoxygenase, 12S-type (ALOX12) catalyses th...
Arachidonate 12-lipoxygenase, 12S-type (ALOX12) catalyses th...
Arachidonate 12-lipoxygenase, 12S-type (ALOX12) converts ara...
Arachidonate 15-lipoxygenase (ALOX15) (Gulliksson et al. 200...
Arachidonate 5-lipoxygenase (ALOX5) (Ueda et al. 1987) conve...
Arachidonate 5-lipoxygenase (ALOX5) catalyzes the first step...
Arachidonate 5-lipoxygenase (ALOX5) catalyzes the formation ...
Arachidonate 5-lipoxygenase (ALOX5) converts 15R-hydro-eicos...
Arachidonate released by phospholipases diffuses within the ...
Arachidonic acid (AA) is a 20 carbon unsaturated fatty acid ...
Arachidonic acid is metabolized via three major enzymatic pa...
Arachidonyl-CoA undergoes a two-carbon chain elongation on t...
ARC co-activator complex and assembly

The ARC co-acti...

Ardbk1 binds to the Smo C-terminal tail as assessed by co-im...
ARF1 helps to recruit AP-1 to Golgi membrane. AP-1 is not al...
ARF4 is a small GTPase that faciliates the targeting of some...
Arginase (ARG1) catalyzes the hydrolysis of arginine to form...
Arginase 2 (ARG2) trimer catalyzes the hydrolysis of arginin...
Arginine is an essential amino acid in chickens. Citrulline,...
Arginine methylation is a common post-translational modifica...
Arginine vasopressin receptor 2 (AVPR2) (Birnbaumer et al. 1...
ARL13B is a ciliary-localized small GTPase with an atypical ...
ARL13B promotes the ciliary localization of INPP5E by intera...
ARL3 hydrolysis of GTP promotes the release of UNC119B, diss...
ARL3 is an ARF-like small GTPase that is localized to the pr...
ARL6 is a small GTPase that was also identified as BBS3, a g...
ARL6:GTP and the BBSome complex are required for the ciliary...
ARMS (Ankyrin-Rich Membrane Spanning/Kidins 220) is a 220kD ...
AroF in complex with reduced FMN catalyzes the dehydration a...
Aromatase (CYP19A1) catalyses the conversion of androstenedi...
Aromatase (CYP19A1) catalyses the conversion of androstenedi...
Aromatic L-amino acid decarboxylase (AADC) catalyzes the dec...
Aromatic L-amino acid decarboxylase (AADC, dopa decarboxylas...
AroQ, which catalyzes the dehydratation of 3-dehydroquinate ...
Around 300 IFN-induced genes have been identified from diffe...
ARPP19 and ENSA, activated by MASTL (GWL) mediated phosphory...
Arresten, the non-collagenous domain (NC1) of alpha-1(IV) co...
Arylsulfatase A (ARSA) (Stein et al. 1989) hydrolyses a sulf...
Arylsulfatase B (ARSB) hydrolyses sulfate from N-acetylgalac...
Arylsulfatase B (ARSB) hydrolyses sulfate from N-acetylgalac...
As a first step towards capturing the array of processes by ...
As a result of binding to Bid, Bax oligomerizes and integrat...
As an alternative to LDLR-mediated uptake and degradation, a...
As binding of WD40 repeats of FBXW7 requires conserved phosp...
As cells enter S phase, HsCdc6p is phosphorylated by CDK pro...
As cGMP is hydrolysed during the activation phase of phototr...
As glutathione conjugates of aflatoxin exo-and endo-epoxides...
As hyaluronan (HA) is synthesised, it is continually extrude...
As inferred from biochemical studies in yeast and phenotypic...
As inferred from bovine homologs, interaction of the cognate...
As inferred from bovine homologs, the 28S ribosomal subunit ...
As inferred from bovine homologs, the 39S ribosomal subunit ...
As inferred from bovine homologs, the ribosome catalyzes for...
As inferred from bovine homologs, the ternary complex contai...
As inferred from bovine homologs, TSFM (EF-Ts, EF-TsMt) acts...
As inferred from bovine homologs, TSFM (EF-Ts, EF-TsMt) acts...
As inferred from bovine homologs, TUFM:GTP (EF-Tu:GTP) binds...
As inferred from bovine mitochondrial homologs, MTIF3 (IF-3M...
As inferred from experiments in vitro with mouse Prdm9, huma...
As inferred from experiments with mouse homologs, primary pi...
As inferred from homologs in Drosophila and mouse, PLD6 (Mit...
As inferred from homologs in mouse, PIWIL2 (HILI in human, h...
As inferred from homologs in mouse, PIWIL4 is loaded with pi...
As inferred from human entities, bovine GFM1 of the GFM1:GTP...
As inferred from human homologs, Bmal1:Clock (Arntl:Clock) h...
As inferred from human homologs, Nr1d1 (Rev-erba) binds the ...
As inferred from human homologs, Nr1d1 (Rev-erba) binds the ...
As inferred from human homologs, Nr1d11 (Rev-erba) binds hem...
As inferred from human homologs, Nr1d11 (Rev-erba) binds its...
As inferred from human RAB proteins, mouse Rab proteins have...
As inferred from mouse (Chen and Shen 2004) both LEFTY1 and ...
As inferred from mouse (Okamura et al. 2000), calcineurin de...
As inferred from mouse (Sano et al. 2007) and rat (Ishikura ...
As inferred from mouse (Turnley et al. 1999) and rat (Salt e...
As inferred from mouse (Ueda et al. 2008, Ueda et al. 2010) ...
As inferred from mouse (Zeigerer et al. 2002) and rat (Uhlig...
As inferred from mouse 3T3-L1 cells, Wnt-1 and Wnt-10b inhib...
As inferred from mouse 3T3-L1 cells, Wnt-1 and Wnt-10b inhib...
As inferred from mouse adipocytes, insulin signals via PKC-l...
As inferred from mouse cell models, histones in silenced rRN...
As inferred from mouse cell models, intergenic spacer region...
As inferred from mouse cell models, long Intergenic Spacer R...
As inferred from mouse cell models, the Nucleolar Remodeling...
As inferred from mouse cell models, the Transcription termin...
As inferred from mouse cells, C/EBPalpha (CEBPA) binds the p...
As inferred from mouse cells, PPARG:RXRA in the absence of f...
As inferred from mouse homologs, after binding PIWIL1 (HIWI ...
As inferred from mouse homologs, after binding PIWIL2 (HILI ...
As inferred from mouse homologs, HENMT1 transfers a methyl g...
As inferred from mouse homologs, HENMT1 transfers a methyl g...
As inferred from mouse homologs, HENMT1 transfers a methyl g...
As inferred from mouse homologs, REV-ERBA (NR1D1) binds the ...
As inferred from mouse homologs, the p-BMAL1:p-CLOCK,NPAS2 h...
As inferred from mouse, Activin binds the Activin receptor c...
As inferred from mouse, AKT2 (PKB-beta) phosphorylates RBC2 ...
As inferred from mouse, AKT2 and, to a lesser extent, AKT1 p...
As inferred from mouse, AKT2 phosphorylates Myosin 5A on ser...
As inferred from mouse, AMPK is activated by AMP and phospho...
As inferred from mouse, ATP7A (Menke's ATPase, MNK) transpor...
As inferred from mouse, binding of Leptin (LEP) to the Lepti...
As inferred from mouse, BMAL1 (ARNTL), CLOCK, and NPAS2 are ...
As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) and BMAL1:...
As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) heterodime...
As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) heterodime...
As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) heterodime...
As inferred from mouse, both non-phosphorylated and phospho...
As inferred from mouse, both non-phosphorylated and phosphor...
As inferred from mouse, Cdk4 interacts with PPARG and enhanc...
As inferred from mouse, CEBPB binds the promoter of the EBF1...
As inferred from mouse, CEBPD binds the promoter of the EBF1...
As inferred from mouse, CyclinD3 interacts with PPARG and en...
As inferred from mouse, DRAP1 binds FOXH1 and inhibits activ...
As inferred from mouse, EGF2 (KROX20) together with KLF4 bin...
As inferred from mouse, FABP1 localizes to the nucleus where...
As inferred from mouse, glucocorticoids bind the glucocortic...
As inferred from mouse, GLUT4 (SLC2A4) initially translocate...
As inferred from mouse, insulin causes phosphorylation and i...
As inferred from mouse, KLF4 together with EGF2 (KROX20) bin...
As inferred from mouse, MEF2C or MEF2D with PGC-1alpha activ...
As inferred from mouse, MSR1 (SCARA1) binds denatured collag...
As inferred from mouse, NF-kappaB inhibits expression of PPA...
As inferred from mouse, NRF2 binds the promoter of the GABPA...
As inferred from mouse, p38 MAPK phosphorylates PGC-1alpha (...
As inferred from mouse, PER proteins can form homodimers and...
As inferred from mouse, PGC-1alpha (PPARGC1A) activates expr...
As inferred from mouse, PGC-1beta (PPARGC1B) binds NRF1 and ...
As inferred from mouse, phosphorylated ATF2 binds the PGC-1a...
As inferred from mouse, phosphorylated CREB enhances express...
As inferred from mouse, RAD51C participates in loading RAD51...
As inferred from mouse, RGC1:RGC2 (RALGAPB:RALGAPA2) activat...
As inferred from mouse, RORA (ROR-alpha) enhances expression...
As inferred from mouse, RORA binds ROR elements (ROREs) in D...
As inferred from mouse, RORA binds RRE DNA elements and recr...
As inferred from mouse, RORA binds RRE DNA elements and recr...
As inferred from mouse, RORA binds RRE DNA elements and recr...
As inferred from mouse, RORA binds RRE DNA elements and recr...
As inferred from mouse, RORA binds the promoter of the SREBF...
As inferred from mouse, SIRT1, an NAD+ dependent deacetylase...
As inferred from mouse, SOCS3 binds LEPR at phosphotyrosine-...
As inferred from mouse, SREBF1A (SREBP1A) and SREBF1C (SREBP...
As inferred from mouse, SREBF1A/1C/2 (SREBP1A/1C/2) bind the...
As inferred from mouse, SREBP1A and SREBP2 bind to the PPARG...
As inferred from mouse, SREBP1A/1C/2 (SREBF1A/1C/2) binds an...
As inferred from mouse, TBC1D1 activates GTPase activity of ...
As inferred from mouse, TC10 participates in the translocati...
As inferred from mouse, TET1, TET2, and TET3 each oxidize 5-...
As inferred from mouse, TET1, TET2, and TET3 oxidize 5-hydro...
As inferred from mouse, TEX15 participates in loading RAD51 ...
As inferred from mouse, TGF-beta inhibits expression of CEPB...
As inferred from mouse, TGF-beta inhibits expression of PPAR...
As inferred from mouse, the BMAL1:CLOCK (ARNTL:CLOCK) hetero...
As inferred from mouse, the BMAL1:CLOCK (ARNTL:CLOCK) hetero...
As inferred from mouse, the kinase inhibitory domain of SOCS...
As inferred from mouse, the phosphorylated BMAL1:CLOCK (ARNT...
As inferred from mouse, the SCARA5:ligand complex is endocyt...
As inferred from mouse, TNF-alpha inhibits expression of CEB...
As inferred from mouse, upon binding Activin AB (INHBA:INHBB...
As inferred from rat
As inferred from rat heart mitochondria, hydrogen peroxide i...
As inferred from rat L6 muscle cells, TBC1D1 is located in t...
As inferred from rat, PGC-1beta activates expression of cyto...
As inferred from rat, SREBF1 binds promoter II of the Acetyl...
As inferred from the cytosolic reaction and from the mitocho...
As inferred from the cytosolic reaction and from the mouse m...
As inferred from the cytosolic reaction, copper chaperone of...
As inferred from the cytosolic reaction, copper chaperone of...
As inferred from the human homolog, Nr1d1 (Rev-erba) binds h...
As inferred from the mouse homolog, UHRF1 associates with he...
As inferred from the response of the activin receptor to act...
As inferred from the response of the activin receptor to act...
As inferred from the yeast MIA40:ERV1 complex, human CHCHD4 ...
As inferred from the yeast SAM50 complex, the human SAMM50 C...
As inferred from the yeast TIM22 complex, human TIMM22 inser...
As inferred from the yeast TIM23 complex, the human TIMM23 c...
As inferred from the yeast TIM23 complex, the human TIMM23 c...
As inferred from the yeast TIM23 complex, the human TIMM23 c...
As inferred from the yeast TIM23 complex, the human TIMM23 c...
As inferred from the yeast TIM8:TIM13 complex, the human TIM...
As inferred from the yeast TIM9:TIM10 complex, the human TIM...
As inferred from the yeast TOM40:TOM70 complex, the human TO...
As inferred from Xenopus (Piccolo 1999) CERBERUS binds NODAL...
As inferred from yeast, the alpha subunit of the mitochondri...
As inferred from yeast, the alpha subunit of the mitochondri...
As influenza viruses bud from the plasma membrane of infecte...
As integrins do not have an intrinsic catalytic activity, th...
As is the case for the WT Hh C-terminal fragment, siRNA depl...
As it hydrolyzes a guanidino group within agmatine and also ...
As long as vitamin A is needed, beta-carotene-monooxygenase ...
As NOTCH1 PEST domain is intracellular, NOTCH1 PEST domain m...
As part of the natural turnover of GAGs, extracellular KSPGs...
As part of the natural turnover of GAGs, extracellular KSPGs...
As part of the natural turnover of GAGs, extracellular KSPGs...
As quiescent G0 cells reenter the cell cycle, p130 (RBL2) is...
As sections of the axial elements form, the telomeres migrat...
As sections of the axial elements form, the telomeres migrat...
As SMAD2 and SMAD3 MH2 domain mutations (Fleming et al. 2013...
As SMAD2 and SMAD3 MH2 domain mutations mainly affect amino ...
As SMAD2 and SMAD3 phosphorylation motif mutants (Fleming et...
As soon as the actin and myosin filaments become competent f...
As TGFBR1 residues phosphorylated by TGFBR2 are upstream of ...
As the active RNA Polymerase I complex leaves the promoter R...
As the channels reopen, rising Ca2+ levels result in binding...
As the collagen peptide chain is translocated across the mem...
As the endosomal lumen acidifies the insulin dissociates fro...
As the reverse transcriptase activity of the HIV-1 RT hetero...
As the reverse transcriptase activity of the HIV-1 RT hetero...
As the signal peptide of the nascent protein enters the lume...
As the sulfate content rises, so does the iduronic acid:gluc...
As well as generating endostatin from collagen XVIII, cathep...
As with other cytokine systems, production of type I IFN is ...
AS160 (TBC1D4) phosphorylated on serines 318, 341, 570, 588,...
As160 (Tbc1d4) phosphorylated on serines 324, 348, 577, 595,...
ASAP1 is a dimeric ARF GTPase activating protein (GAP) and s...
ASC (adaptor protein apoptosis-associated speck-like protein...
Ascorbate (vitamin C) can reduce the BH3 radical back to BH4...
Aspirin (acetylsalicylate) reacts spontaneously with one sub...
Aspirin (acetylsalicylate) reacts spontaneously with one sub...
Aspirin acetylates the cyclooxygenase, prostaglandin G/H syn...
Assembling Gag molecules are largely derived from the rapidl...
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-stran...
Association of 14-3-3 proteins with phosphorylated CDC25C (p...
Association of cytosolic FAS into multimers is linked to inc...
Association of EGFRvIII mutant with HSP90 chaperone protein ...
Association of HSP90 with active dimers of phospho-EGFR KD m...
Association of SHB with VEGFR2 leads to its Src-dependent ty...
Association with RIP2 and its phosphorylation allows subsequ...
At G1 entry from G0, p130 (RBL2) is phosphorylated on three ...
At higher concentrations of extracellular ATP, the P2X7 chan...
At higher concentrations of ligand, a substantial fraction o...
At least four neuropeptide Y receptor subtypes each with spe...
At least three different classes of negative regulators exis...
At least two mechanisms of transport of proteins from the ER...
At low to intermediate concentrations of extracellular ATP, ...
At mitotic entry Plk1 phosphorylates and inhibits Myt1 activ...
At mitotic entry, Plk1 phosphorylates and activates Cdc25C p...
At physiological pH serum amyloid P component is a decamer o...
At resting membrane potential the NMDA receptor is blocked b...
At some point eIF4E binds the mature mRNA. While TAP and Aly...
At some point in the extension process a sufficient number o...
At the base of the cilium, retrograde trains are believed to...
At the beginning of mitosis, MASTL (GWL, Greatwall kinase) i...
At the beginning of this reaction, 1 molecule of '(S)-3-Hydr...
At the beginning of this reaction, 1 molecule of '(S)-Hydrox...
At the beginning of this reaction, 1 molecule of '1-Phosphat...
At the beginning of this reaction, 1 molecule of '2-Amino-3-...
At the beginning of this reaction, 1 molecule of '2-Amino-3-...
At the beginning of this reaction, 1 molecule of '2-trans-Do...
At the beginning of this reaction, 1 molecule of '3' overhan...
At the beginning of this reaction, 1 molecule of '3',5'-Cycl...
At the beginning of this reaction, 1 molecule of '3-Oxodecan...
At the beginning of this reaction, 1 molecule of '3-Oxododec...
At the beginning of this reaction, 1 molecule of '3-Oxohexan...
At the beginning of this reaction, 1 molecule of '3-Oxooctan...
At the beginning of this reaction, 1 molecule of '3-Oxopalmi...
At the beginning of this reaction, 1 molecule of '3-Oxotetra...
At the beginning of this reaction, 1 molecule of '3-phosphoi...
At the beginning of this reaction, 1 molecule of '53BP1', an...
At the beginning of this reaction, 1 molecule of '53BP1:H2AX...
At the beginning of this reaction, 1 molecule of '70S:Met-tR...
At the beginning of this reaction, 1 molecule of '80S:Met-tR...
At the beginning of this reaction, 1 molecule of '80S:mRNA:a...
At the beginning of this reaction, 1 molecule of 'Acetaminop...
At the beginning of this reaction, 1 molecule of 'activated ...
At the beginning of this reaction, 1 molecule of 'activated ...
At the beginning of this reaction, 1 molecule of 'activated ...
At the beginning of this reaction, 1 molecule of 'Aminoacyl-...
At the beginning of this reaction, 1 molecule of 'AMPK heter...
At the beginning of this reaction, 1 molecule of 'Arrested p...
At the beginning of this reaction, 1 molecule of 'ATAC B Com...
At the beginning of this reaction, 1 molecule of 'ATAC C Com...
At the beginning of this reaction, 1 molecule of 'ATAC C Com...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'ATP', and ...
At the beginning of this reaction, 1 molecule of 'Bovine Suc...
At the beginning of this reaction, 1 molecule of 'c-Jun-P', ...
At the beginning of this reaction, 1 molecule of 'CBP80', an...
At the beginning of this reaction, 1 molecule of 'Cdc20:phos...
At the beginning of this reaction, 1 molecule of 'CDC6', and...
At the beginning of this reaction, 1 molecule of 'Cdk 9 prot...
At the beginning of this reaction, 1 molecule of 'CDT1', and...
At the beginning of this reaction, 1 molecule of 'ChREBP pro...
At the beginning of this reaction, 1 molecule of 'cis,cis-3,...
At the beginning of this reaction, 1 molecule of 'Collagen I...
At the beginning of this reaction, 1 molecule of 'Crotonoyl-...
At the beginning of this reaction, 1 molecule of 'Cyclin B2:...
At the beginning of this reaction, 1 molecule of 'Cyclin D1:...
At the beginning of this reaction, 1 molecule of 'Cyclin E2:...
At the beginning of this reaction, 1 molecule of 'D-methylma...
At the beginning of this reaction, 1 molecule of 'Decanoyl-C...
At the beginning of this reaction, 1 molecule of 'DNA polyme...
At the beginning of this reaction, 1 molecule of 'DNA-PK syn...
At the beginning of this reaction, 1 molecule of 'DNA-PK syn...
At the beginning of this reaction, 1 molecule of 'dNTP', 1 m...
At the beginning of this reaction, 1 molecule of 'dNTP', 1 m...
At the beginning of this reaction, 1 molecule of 'dNTP', 1 m...
At the beginning of this reaction, 1 molecule of 'dNTP', 1 m...
At the beginning of this reaction, 1 molecule of 'dRb1 prote...
At the beginning of this reaction, 1 molecule of 'DSIF:NELF:...
At the beginning of this reaction, 1 molecule of 'dsRNA dupl...
At the beginning of this reaction, 1 molecule of 'dsRNA dupl...
At the beginning of this reaction, 1 molecule of 'dTTP', 1 m...
At the beginning of this reaction, 1 molecule of 'Editosome ...
At the beginning of this reaction, 1 molecule of 'eEF1B alph...
At the beginning of this reaction, 1 molecule of 'eEF2', and...
At the beginning of this reaction, 1 molecule of 'eIF4E', an...
At the beginning of this reaction, 1 molecule of 'eIF4E:4E-B...
At the beginning of this reaction, 1 molecule of 'elongating...
At the beginning of this reaction, 1 molecule of 'Elongation...
At the beginning of this reaction, 1 molecule of 'Elongation...
At the beginning of this reaction, 1 molecule of 'Elongin A1...
At the beginning of this reaction, 1 molecule of 'Elongin B ...
At the beginning of this reaction, 1 molecule of 'ERCC1, DNA...
At the beginning of this reaction, 1 molecule of 'eRF3-GDP:e...
At the beginning of this reaction, 1 molecule of 'eRF3-GTP:e...
At the beginning of this reaction, 1 molecule of 'FA anion:U...
At the beginning of this reaction, 1 molecule of 'FACT 140 k...
At the beginning of this reaction, 1 molecule of 'FACT compl...
At the beginning of this reaction, 1 molecule of 'FACT compl...
At the beginning of this reaction, 1 molecule of 'FACT compl...
At the beginning of this reaction, 1 molecule of 'FAD', and ...
At the beginning of this reaction, 1 molecule of 'Fatty Acid...
At the beginning of this reaction, 1 molecule of 'Fatty Acid...
At the beginning of this reaction, 1 molecule of 'fibrin mul...
At the beginning of this reaction, 1 molecule of 'fibrin mul...
At the beginning of this reaction, 1 molecule of 'geminin', ...
At the beginning of this reaction, 1 molecule of 'geminin:ub...
At the beginning of this reaction, 1 molecule of 'GP VI:Fc E...
At the beginning of this reaction, 1 molecule of 'GPI-anchor...
At the beginning of this reaction, 1 molecule of 'GTP', and ...
At the beginning of this reaction, 1 molecule of 'GTP', and ...
At the beginning of this reaction, 1 molecule of 'H+', 1 mol...
At the beginning of this reaction, 1 molecule of 'H+', 1 mol...
At the beginning of this reaction, 1 molecule of 'H+', and 1...
At the beginning of this reaction, 1 molecule of 'H2O', and ...
At the beginning of this reaction, 1 molecule of 'H2O', and ...
At the beginning of this reaction, 1 molecule of 'H2O', and ...
At the beginning of this reaction, 1 molecule of 'Hexanoyl-C...
At the beginning of this reaction, 1 molecule of 'HIV-1 arre...
At the beginning of this reaction, 1 molecule of 'HIV-1 init...
At the beginning of this reaction, 1 molecule of 'HIV-1 init...
At the beginning of this reaction, 1 molecule of 'HIV-1 open...
At the beginning of this reaction, 1 molecule of 'HIV-1 open...
At the beginning of this reaction, 1 molecule of 'HIV-1 Prom...
At the beginning of this reaction, 1 molecule of 'HIV-1 Tat-...
At the beginning of this reaction, 1 molecule of 'HIV-1 tran...
At the beginning of this reaction, 1 molecule of 'HIV-1 tran...
At the beginning of this reaction, 1 molecule of 'HIV-1 tran...
At the beginning of this reaction, 1 molecule of 'Inactive r...
At the beginning of this reaction, 1 molecule of 'insulin' i...
At the beginning of this reaction, 1 molecule of 'Lauroyl-Co...
At the beginning of this reaction, 1 molecule of 'Magoh-Y14 ...
At the beginning of this reaction, 1 molecule of 'mChREBP' i...
At the beginning of this reaction, 1 molecule of 'mChREBP', ...
At the beginning of this reaction, 1 molecule of 'Mcm10:acti...
At the beginning of this reaction, 1 molecule of 'Mcm10:pre-...
At the beginning of this reaction, 1 molecule of 'Mcm2-7 com...
At the beginning of this reaction, 1 molecule of 'MDC1/NFBD1...
At the beginning of this reaction, 1 molecule of 'Mdm2' is p...
At the beginning of this reaction, 1 molecule of 'MRE11:RAD5...
At the beginning of this reaction, 1 molecule of 'mRNA cappi...
At the beginning of this reaction, 1 molecule of 'mRNA cappi...
At the beginning of this reaction, 1 molecule of 'multiubiqu...
At the beginning of this reaction, 1 molecule of 'myristoyl-...
At the beginning of this reaction, 1 molecule of 'NAD+', and...
At the beginning of this reaction, 1 molecule of 'NAD+', and...
At the beginning of this reaction, 1 molecule of 'NAD+', and...
At the beginning of this reaction, 1 molecule of 'NAD+', and...
At the beginning of this reaction, 1 molecule of 'NAD+', and...
At the beginning of this reaction, 1 molecule of 'NELF-A pro...
At the beginning of this reaction, 1 molecule of 'newly synt...
At the beginning of this reaction, 1 molecule of 'NH4+', 1 m...
At the beginning of this reaction, 1 molecule of 'Octanoyl-C...
At the beginning of this reaction, 1 molecule of 'Orc1:Orc4:...
At the beginning of this reaction, 1 molecule of 'Orc2:origi...
At the beginning of this reaction, 1 molecule of 'Orc3:Orc2:...
At the beginning of this reaction, 1 molecule of 'Orc4', and...
At the beginning of this reaction, 1 molecule of 'Orc4:Orc5:...
At the beginning of this reaction, 1 molecule of 'ORC:origin...
At the beginning of this reaction, 1 molecule of 'ORC:origin...
At the beginning of this reaction, 1 molecule of 'origin of ...
At the beginning of this reaction, 1 molecule of 'Oxygen', 1...
At the beginning of this reaction, 1 molecule of 'palmitoyl-...
At the beginning of this reaction, 1 molecule of 'PAPS', and...
At the beginning of this reaction, 1 molecule of 'PAPS', and...
At the beginning of this reaction, 1 molecule of 'pChREBP (S...
At the beginning of this reaction, 1 molecule of 'pChREBP (T...
At the beginning of this reaction, 1 molecule of 'pChREBP(Se...
At the beginning of this reaction, 1 molecule of 'peptidyl-t...
At the beginning of this reaction, 1 molecule of 'Phosphatid...
At the beginning of this reaction, 1 molecule of 'phospho-IR...
At the beginning of this reaction, 1 molecule of 'phospho-IR...
At the beginning of this reaction, 1 molecule of 'phospho-Re...
At the beginning of this reaction, 1 molecule of 'phospho-SH...
At the beginning of this reaction, 1 molecule of 'phospho-SH...
At the beginning of this reaction, 1 molecule of 'phosphoryl...
At the beginning of this reaction, 1 molecule of 'PKB:PKB Re...
At the beginning of this reaction, 1 molecule of 'plasminoge...
At the beginning of this reaction, 1 molecule of 'Pol II Ini...
At the beginning of this reaction, 1 molecule of 'Pol II ini...
At the beginning of this reaction, 1 molecule of 'pol II ope...
At the beginning of this reaction, 1 molecule of 'pol II ope...
At the beginning of this reaction, 1 molecule of 'Pol II Pro...
At the beginning of this reaction, 1 molecule of 'pol II tra...
At the beginning of this reaction, 1 molecule of 'pol II tra...
At the beginning of this reaction, 1 molecule of 'Pol II tra...
At the beginning of this reaction, 1 molecule of 'POLRMT:TFB...
At the beginning of this reaction, 1 molecule of 'pPF2K-Pase...
At the beginning of this reaction, 1 molecule of 'prChREBP (...
At the beginning of this reaction, 1 molecule of 'prChREBP (...
At the beginning of this reaction, 1 molecule of 'prChREBP (...
At the beginning of this reaction, 1 molecule of 'pro-factor...
At the beginning of this reaction, 1 molecule of 'pro-factor...
At the beginning of this reaction, 1 molecule of 'pro-factor...
At the beginning of this reaction, 1 molecule of 'pro-protei...
At the beginning of this reaction, 1 molecule of 'pro-protei...
At the beginning of this reaction, 1 molecule of 'pro-protei...
At the beginning of this reaction, 1 molecule of 'pro-protei...
At the beginning of this reaction, 1 molecule of 'pro-prothr...
At the beginning of this reaction, 1 molecule of 'Processive...
At the beginning of this reaction, 1 molecule of 'Processive...
At the beginning of this reaction, 1 molecule of 'prPF2K-Pas...
At the beginning of this reaction, 1 molecule of 'PSF3p', 1 ...
At the beginning of this reaction, 1 molecule of 'RAD50:MRE1...
At the beginning of this reaction, 1 molecule of 'RAD51', an...
At the beginning of this reaction, 1 molecule of 'RAD52', an...
At the beginning of this reaction, 1 molecule of 'rAMPK hete...
At the beginning of this reaction, 1 molecule of 'rChREBP' i...
At the beginning of this reaction, 1 molecule of 'Replicatio...
At the beginning of this reaction, 1 molecule of 'RNA Pol II...
At the beginning of this reaction, 1 molecule of 'RNA Pol II...
At the beginning of this reaction, 1 molecule of 'RNA primer...
At the beginning of this reaction, 1 molecule of 'rPF2K-Pase...
At the beginning of this reaction, 1 molecule of 'Secreted f...
At the beginning of this reaction, 1 molecule of 'SMAC', and...
At the beginning of this reaction, 1 molecule of 'SMAC', and...
At the beginning of this reaction, 1 molecule of 'Stalled Po...
At the beginning of this reaction, 1 molecule of 'SUPT5H pro...
At the beginning of this reaction, 1 molecule of 'TAP:3'-pol...
At the beginning of this reaction, 1 molecule of 'TFIIIB:TFI...
At the beginning of this reaction, 1 molecule of 'trans-Dec-...
At the beginning of this reaction, 1 molecule of 'trans-Hex-...
At the beginning of this reaction, 1 molecule of 'trans-Tetr...
At the beginning of this reaction, 1 molecule of 'Transcript...
At the beginning of this reaction, 1 molecule of 'Transcript...
At the beginning of this reaction, 1 molecule of 'Transcript...
At the beginning of this reaction, 1 molecule of 'ubiquitin'...
At the beginning of this reaction, 1 molecule of 'ubiquitin'...
At the beginning of this reaction, 1 molecule of 'ubiquitin'...
At the beginning of this reaction, 1 molecule of 'Ubiquitina...
At the beginning of this reaction, 1 molecule of 'ubiquitina...
At the beginning of this reaction, 1 molecule of 'ubiquitina...
At the beginning of this reaction, 1 molecule of 'XIAP:Caspa...
At the beginning of this reaction, 1 molecule of '{(1,6)-alp...
At the beginning of this reaction, 1 molecule of each of POL...
At the beginning of this reaction, 10 molecules of 'Oxygen',...
At the beginning of this reaction, 10 molecules of 'Oxygen',...
At the beginning of this reaction, 11 molecules of 'Oxygen',...
At the beginning of this reaction, 11 molecules of 'Oxygen',...
At the beginning of this reaction, 12 molecules of 'Oxygen',...
At the beginning of this reaction, 2 molecules of 'ADAR1 pro...
At the beginning of this reaction, 2 molecules of 'ADAR2 pro...
At the beginning of this reaction, 2 molecules of 'ATP', and...
At the beginning of this reaction, 2 molecules of 'ATP', and...
At the beginning of this reaction, 2 molecules of 'ATP', and...
At the beginning of this reaction, 2 molecules of 'ATP', and...
At the beginning of this reaction, 2 molecules of 'ATP', and...
At the beginning of this reaction, 2 molecules of 'phospho-E...
At the beginning of this reaction, 3 molecules of 'ATP', and...
At the beginning of this reaction, 3 molecules of 'ATP', and...
At the beginning of this reaction, 3 molecules of 'ATP', and...
At the beginning of this reaction, 3 molecules of 'ubiquitin...
At the beginning of this reaction, 4 molecules of 'ATP', and...
At the beginning of this reaction, 4 molecules of 'ATP', and...
At the beginning of this reaction, 8 molecules of 'Oxygen', ...
At the center of the mammalian circadian clock is a negative...
At the center of the mouse circadian clock is a negative tra...
At the early endosome membrane, myotubularin (MTM1), myotubu...
At the early endosome membrane, myotubularin (MTM1), myotubu...
At the early endosome membrane, phosphatidylinositol 3,5-bis...
At the early endosome membrane, phosphatidylinositol 3-kinas...
At the early endosome membrane, phosphatidylinositol 4-kinas...
At the early endosome membrane, phosphatidylinositol-4-phosp...
At the early endosome membrane, the PAS complex, consisting ...
At the early endosome membrane, the PAS complex, consisting ...
At the early endosome membrane, the PAS complex, consisting ...
At the early endosome membrane, type I (INPP4A) (Norris et a...
At the end of this reaction, 1 molecule of '1-acyl-sn-glycer...
At the end of this reaction, 1 molecule of 'Acetyl-CoA carbo...
At the end of this reaction, 1 molecule of 'Cdc6' is present...
At the end of this reaction, 1 molecule of 'citrate lyase mo...
At the end of this reaction, 1 molecule of 'Cyclin B:Cdk1 co...
At the end of this reaction, 1 molecule of 'Fatty acid synth...
At the end of this reaction, 1 molecule of 'Pyruvate kinase ...
At the end of this reaction, 1 molecule of 'pyruvate kinase,...
At the endoplasmic reticulum (ER) membrane, 1-acyl lysophosp...
At the endoplasmic reticulum (ER) membrane, 1-acyl lysophosp...
At the endoplasmic reticulum (ER) membrane, 1-acyl-lysophosp...
At the endoplasmic reticulum (ER) membrane, 2-acyl lysophosp...
At the endoplasmic reticulum (ER) membrane, 2-acyl lysophosp...
At the endoplasmic reticulum (ER) membrane, a 2-monoacylglyc...
At the endoplasmic reticulum (ER) membrane, active membrane-...
At the endoplasmic reticulum (ER) membrane, active membrane-...
At the endoplasmic reticulum (ER) membrane, CDP-diacylglycer...
At the endoplasmic reticulum (ER) membrane, choline/ethanola...
At the endoplasmic reticulum (ER) membrane, choline/ethanola...
At the endoplasmic reticulum (ER) membrane, diacylglycerol (...
At the endoplasmic reticulum (ER) membrane, lysocardiolipin ...
At the endoplasmic reticulum (ER) membrane, lysocardiolipin ...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, lysophospholipid...
At the endoplasmic reticulum (ER) membrane, membrane-bound c...
At the endoplasmic reticulum (ER) membrane, membrane-bound c...
At the endoplasmic reticulum (ER) membrane, monoglyceride li...
At the endoplasmic reticulum (ER) membrane, patatin-like pho...
At the endoplasmic reticulum (ER) membrane, phosphatidate cy...
At the endoplasmic reticulum (ER) membrane, phosphatidate ph...
At the endoplasmic reticulum (ER) membrane, phosphatidic aci...
At the endoplasmic reticulum (ER) membrane, phosphatidic aci...
At the endoplasmic reticulum (ER) membrane, phosphatidylchol...
At the endoplasmic reticulum (ER) membrane, phosphatidylchol...
At the endoplasmic reticulum (ER) membrane, phosphatidylchol...
At the endoplasmic reticulum (ER) membrane, phosphatidylchol...
At the endoplasmic reticulum (ER) membrane, phosphatidyletha...
At the endoplasmic reticulum (ER) membrane, phosphatidyletha...
At the endoplasmic reticulum (ER) membrane, phosphatidyletha...
At the endoplasmic reticulum (ER) membrane, phosphatidyletha...
At the endoplasmic reticulum (ER) membrane, phosphatidyletha...
At the endoplasmic reticulum (ER) membrane, phosphatidylglyc...
At the endoplasmic reticulum (ER) membrane, phosphatidylglyc...
At the endoplasmic reticulum (ER) membrane, phosphatidylglyc...
At the endoplasmic reticulum (ER) membrane, phosphatidylinos...
At the endoplasmic reticulum (ER) membrane, phosphatidylinos...
At the endoplasmic reticulum (ER) membrane, phosphatidylinos...
At the endoplasmic reticulum (ER) membrane, phosphatidylinos...
At the endoplasmic reticulum (ER) membrane, phosphatidylinos...
At the endoplasmic reticulum (ER) membrane, phosphatidylseri...
At the endoplasmic reticulum (ER) membrane, phosphatidylseri...
At the endoplasmic reticulum (ER) membrane, phosphatidylseri...
At the endoplasmic reticulum (ER) membrane, phosphatidylseri...
At the endoplasmic reticulum (ER) membrane, phosphatidylseri...
At the endoplasmic reticulum (ER) membrane, phosphoinositide...
At the endoplasmic reticulum (ER) membrane, transmembrane pr...
At the endoplasmic reticulum (ER) membrane, triacylglycerol ...
At the endoplasmic reticulum (ER) membrane, two 2-monoacylgl...
At the ER membrane, phosphatidylcholine (PC) is exchanged fo...
At the G1/S transition, the Cdh1 (FZR1) subunit of the APC/C...
At the G1/S transition, the Cdh1 subunit of the APC:Cdh1 com...
At the Golgi membrane, activated phosphatidylinositol 4-kina...
At the Golgi membrane, ADP-ribosylation factor 1 and 3 (ARF1...
At the Golgi membrane, cholinephosphotransferase 1 (CHPT1) c...
At the Golgi membrane, phosphatidylinositide phosphatase SAC...
At the Golgi membrane, phosphatidylinositide phosphatase SAC...
At the Golgi membrane, phosphatidylinositol (PI) is exchange...
At the Golgi membrane, phosphatidylinositol 3-kinase catalyt...
At the Golgi membrane, phosphatidylinositol 4-kinase alpha (...
At the Golgi membrane, phosphatidylinositol 4-phosphate (PI4...
At the Golgi membrane, phosphatidylinositol 4-phosphate (PI4...
At the Golgi membrane, phosphatidylinositol-3,4,5-trisphosph...
At the Golgi membrane, phosphatidylinositol-4-phosphate 3-ki...
At the Golgi membrane, the PAS complex, consisting of FYVE f...
At the Golgi membrane, the PAS complex, consisting of FYVE f...
At the Golgi membrane, the PAS complex, consisting of mouse ...
At the inner mitochondrial (IM) membrane, CDP-diacylglycerol...
At the inner mitochondrial (IM) membrane, phosphatidate cyti...
At the inner mitochondrial (IM) membrane, phosphatidylserine...
At the inner mitochondrial (IM) membrane, PTPMT1 (phosphatid...
At the inner mitochondrial (IM) membrane, Ptpmt1 (phosphatid...
At the inner mitochondrial (IR) membrane, cardiolipin syntha...
At the inner mitochondrial (IR) membrane, phosphatidylglycer...
At the inner mitochondrial membrane (IM), calcium-independen...
At the inner mitochondrial membrane (IM), cardiolipin syntha...
At the inner mitochondrial membrane (IM), cardiolipin syntha...
At the inner mitochondrial membrane (IM), phosphatidylglycer...
At the inner mitochondrial membrane (IM), tafazzin (TAZ) con...
At the inner mitochondrial membrane (IM), tafazzin (TAZ) con...
At the inner mitochondrial membrane (IM), tafazzin (TAZ) con...
At the inner mitochondrial membrane (IM), tafazzin (TAZ) con...
At the inner mitochondrial membrane (IM), the phospholipase ...
At the inner mitochondrial membrane (IM), the trifunctional ...
At the late endosome membrane, myotubularin (MTM1), myotubul...
At the late endosome membrane, myotubularin (MTM1), myotubul...
At the late endosome membrane, phosphatidylinositol 3-kinase...
At the late endosome membrane, the PAS complex, consisting o...
At the late endosome membrane, the PAS complex, consisting o...
At the late endosome membrane, the PAS complex, consisting o...
At the late endosome membrane, the PAS complex, consisting o...
At the late endosome membrane, the PAS complex, consisting o...
At the late endosome membrane, the primary event is the deph...
At the onset of mitosis, Cdh1 is phosphorylated by Cyclin B-...
At the onset of mitosis, cyclin B is phosphorylated in the C...
At the onset of mitosis, Cyclin B1 is phosphorylated in the ...
At the outer mitochondrial (OM) membrane, 1-acyl lysophospha...
At the outer mitochondrial (OM) membrane, phosphatidic acid ...
At the plasma membrane, a group of phospholipase C (“PLC(bz)...
At the plasma membrane, phosphatidic acid (PA) is hydrolyzed...
At the plasma membrane, phosphatidylcholine (PC) is hydrolyz...
At the plasma membrane, phosphatidylcholine (PC) is hydrolyz...
At the plasma membrane, phosphatidylethanolamine (PE) is hyd...
At the plasma membrane, phosphatidylglycerol (PG) is hydroly...
At the plasma membrane, phosphatidylinositol (PI) is hydroly...
At the plasma membrane, phosphatidylinositol 4-kinase type 2...
At the plasma membrane, phosphatidylinositol 5-phosphatases ...
At the plasma membrane, phosphatidylinositol-3,4,5-trisphosp...
At the plasma membrane, phosphatidylinositol-3,4,5-trisphosp...
At the plasma membrane, phosphatidylinositol-4,5-bisphosphat...
At the plasma membrane, phosphatidylinositol-4,5-bisphosphat...
At the plasma membrane, phosphatidylinositol-4-phosphate 5-k...
At the plasma membrane, phosphatidylinositol-4-phosphate 5-k...
At the plasma membrane, phosphatidylinositol-4-phosphate 5-k...
At the plasma membrane, phosphatidylinositol-4-phosphate 5-k...
At the plasma membrane, phosphatidylinositol-5-phosphate 4-k...
At the plasma membrane, phosphatidylinositol-5-phosphate 4-k...
At the plasma membrane, phosphatidylserine (PS) is hydrolyze...
At the plasma membrane, subsequent phosphorylation of phosph...
At the plasma membrane, synaptic inositol-1,4,5-trisphosphat...
At the plasma membrane, synaptic inositol-1,4,5-trisphosphat...
At the plasma membrane, Synaptojanin-1 (SYNJ1) and -2 (SYNJ2...
At the plasma membrane, synaptojanin-1 aka Synaptic inositol...
At the plasma membrane, synaptojanin-1 aka Synaptic inositol...
At the plasma membrane, type I and type II inositol-3,4-bisp...
At the site of damage, the Pol II complex is arrested result...
At the sites of vascular injury bioactive molecules such as ...
At the start of the cycle a myosin head lacking a bound nucl...
At the start of the elongation phase of DNA replication, the...
At the stellate cell surface, all-trans-retinol (atROL) bind...
ATF2 (activating transcription factor 2) is a basic leucine ...
ATF4 is a transcription factor and activates expression of I...
ATF6-alpha is a transmembrane protein located in the endopla...
ATF6-alpha is a transmembrane protein that normally resides ...
ATF6-alpha is cleaved by S1P after amino acid 419 (RHLL). It...
ATM is present in unirradiated cells as a dimer or higher-or...
ATM mediated phosphorylation of BRCA1 at serine residues S11...
ATM mediated phosphorylation of MDC1/NFBD1 may be involved i...
ATM phosphorylates COP1 on Ser387 in response to DNA damage ...
ATM phosphorylation promotes autoubiquitination of COP1 in v...
ATM, a serine-threonine kinase, belongs to a large family wi...
ATM-dependent phosphorylation of COP1 on Ser(387) results in...
ATP bound G-actin monomers are added to the fast growing bar...
ATP sensitive K+ channels couple intracellular metabolism wi...
ATP-binding cassette protein A4 (ABCA4, ABCR), expressed exc...
ATP-binding cassette sub-family B member 9 (ABCB9, aka lysos...
ATP-binding cassette sub-family D member 4 (ABCD4), original...
ATP-binding cassette sub-family F member 1 (ABCF1 aka ABC50)...
ATP-binding cassette sub-family G member 2 (Abcg2), associat...
ATP-binding cassette sub-family G member 2 (ABCG2), associat...
ATP-sensitive potassium channels (KATP channels) bind ATP an...
ATP-sensitive Potassium channels open and allow an inward re...
Atp7a (Menke's ATPase, Mnk) transports copper from Atox in t...
ATR and ATM dependent phosphorylation of FANCD2 promotes th...
ATR kinase activity is stimulated upon binding of the ATR-AT...
Attenuation of the heat shock transcriptional response occur...
Atypical PKC isoforms phosphorylate the beta subunit of the ...
AUF1 (hnRNP D0) binds AU-rich elements in mRNAs encoding Int...
AUF1 (hnRNP D0) dimers bind U-rich regions of AU-rich elemen...
AUF1 is ubiquitinated at unknown sites. The number of ubiqui...
AUF1 monomers form dimers which bind the U-rich sequences in...
AURKA (Aurora A kinase) activation through autophosphorylati...
AURKA (Aurora A kinase) phosphorylates PLK1 on threonine res...
Aurora kinase B (AURKB), which is part of the kinetochore, p...
Auto-PARylated (poly(ADP-ribosylated)) PARP1 or PARP2 homodi...
Autophagy protein 5 (ATG5) and autophagy-related protein 12 ...
Autophosphorylated EGFR tyrosine residues are docking sites ...
Autophosphorylation of Y397 on FAK1 provides a high affinit...
Autophosphorylation of ATM results in the dissociation of t...
Autophosphorylation of DNA-PKcs is required for NHEJ in vivo...
Autophosphorylation of serine/threonine-protein kinase PAK1 ...
Autophosphorylation of the insulin receptor triggers a serie...
Autophosphorylation of the N-terminus Ser12-Ser13 is require...
Autoproteolytic processing of the Hh precursor is essential ...
Autosomal dominant mutations in FGFR2 are associated with th...
Autosomal dominant TRAF3 deficiency caused by heterozygous m...
Autosomal recessive (AR) IRAK-4 deficiency leads to impaired...
Autosomal recessive IRAK-4 deficiency leads to impaired TLR ...
Autoubiquitinated COP1 is degraded by the proteasome. The nu...
Axial elements begin assembling as short linear segments alo...
Axial elements begin assembling as short linear segments alo...
AXIN is believed to be dephosphorylated upon WNT pathway sti...
AXIN is present in low concentrations in the cell and is con...
AXIN1 and AXIN2 are critical scaffolding proteins of the bet...
AXIN1 was first identified as the product of the mouse gene ...
Axl with its two phopshorylated YxxM motifs associates with ...
AXL/UFO (Tyrosine-protein kinase receptor UFO) is a member o...
Axon guidance / axon pathfinding is the process by which neu...
Axonin-1 expressed on the commissural axons interacts in tra...
AZD4547 (Astra Zeneca) is a pan-FGFR inhibitor in Phase I cl...
“CERT” (ceramide transfer protein) can dissociate from its c...
“CERT” (ceramide transfer protein), associated with the cyto...
B-cell lymphoma/leukemia 10 (BCL10) is the downstream signal...
B-TrCP associates with phosphorylated beta-catenin through t...
B23 may function as a shuttle for the import of HIV Rev from...
B3GAT1 (Kitagawa et al. 1998), 2 (Marcos et al. 2002) and 3 ...
B3GAT3 (Ouzzine et al. 2000), along with B3GAT1 and 2, trans...
B4GALT1 (beta-1,4-galactosyltransferase 1) in the Golgi memb...
Bacillus anthracis bacteria target cells in an infected huma...
Bacterioferritin, like ferritin, is a spherical shell-like p...
BAG4, also known as silencer of death domain (SODD), belongs...
BAMBI (BMP and activin membrane-bound inhibitor) is a transm...
BANF1 (BAF i.e. barrier-to-autointegration factor) is a DNA-...
Base excision repair is initiated by a DNA glycosylase which...
Base excision repair is initiated by DNA glycosylases that h...
Base excision repair is initiated by DNA glycosylases that h...
Based on analogy with studies of the BCR-ABL fusion, phospho...
Based on in vitro affinity chromatography study, basigin was...
Based on structural and functional studies of PIK3CA E542K m...
Based on structural and functional studies of PIK3CA E542K m...
Based on structural and functional studies of PIK3CA Q546K m...
Based on structural and functional studies of PIK3CA Q546K m...
Based on structural and functional studies of PIK3CA Q546K m...
Based on structural and functional studies of PIK3CA Q546K m...
Based on structural and functional studies of PIK3CA Q546L m...
Based on structural and functional studies of the PIK3CA E54...
Based on structural and functional studies of the PIK3CA E54...
Based on structural and functional studies of the PIK3CA E54...
Based on studies done in C. reinhardtii, C. elegans and mous...
Based on studies in mouse, human VANGL2 is predicted to be p...
Based on studies of presenilin-1 (Psen1) deficient mouse emb...
Based on the wild-type EGFR signaling, it is assumed that th...
Based on the wild-type EGFR signaling, it is assumed that th...
Based on work done in C. reinhardtii and Trypanosoma brucei,...
Basigin (Bsg) is a highly glycosylated transmembrane protein...
Basigin expressed on the surface of most tumor cells, stimul...
Basigin is a widely distributed cell-surface protein with tw...
Basigin is a widely expressed transmembrane glycoprotein tha...
Basigin serves as a signaling receptor for extracellular cyc...
Bcl-2 interacts with tBid (Yi et al. 2003), BIM (Puthalakath...
BCL10 and MALT1 proteins form high molecular weight oligomer...
Bcl10 interacts with the oligomerized CARMA1 and this is med...
Bcl10 is recruited to activated, oligomeric CARMA1 through a...
BCL10-MALT1 oligomers bind to TRAF6 and this inturn promotes...
BCL2 binds tBID and inhibits BID-induced cytochrome C releas...
Because of their hydrophobicity, lipids are found in the ext...
Before rejoining of the broken DNA ends can occur, endonucle...
Before the cargo vesicle can fuse with target membrane, the ...
Benzene is an occupational and environmental toxicant and is...
Benzoate and ATP react with coenzyme A to form benzoyl CoA, ...
Benzoic acid, widely used as a food preservative, is convert...
Benzoquinoid ansamycins (geldanamycin, herbimycin, and gelda...
Benzoyl CoA and glycine react to form benzoyl glycine (hippu...
Besides adhesive roles in cell cell interaction, L1 function...
Besides autophosphorylation, EGFR can become tyrosine-phosph...
Besides CRK, FRS2 also binds GRB2, the cyclin-dependent kina...
Besides recognizing 8-oxoguanine in the oxidation-damaged DN...
Besides signaling as a transmembrane receptor, ligand activa...
Besides signalling through the tyrosine kinase receptors TRK...
Besides the RAF kinase, RAS can activate several ral guanine...
Bestrophins 1-4 (BEST1-4, aka vitelliform macular dystrophy ...
Beta 1,4 galactosyltransferase 7 (B4GALT7) adds galactose (G...
Beta adrenoceptors couple with G protein alpha-s subtype (We...
Beta arrestin 1 and 2 (Arrb1 and 2) and Kif3a are required f...
Beta defensin 103 (hBD-3) can induce expression of the costi...
Beta defensin precursors are more simple in structure than t...
Beta tubulin within the active (Factor E:alpha tubulin: Fact...
Beta,beta-carotene 9',10'-oxygenase (BCO2) is able to eccent...
Beta-1,3-galactosyltransferase 6 (B3GALT6) transfers a secon...
Beta-1,4-galactosyltransferase 1 (B4GALT1) is a Golgi membra...
Beta-1,4-galactosyltransferase 5 (B4GALT5) mediates the tran...
Beta-1,4-galactosyltransferase 7 (B4GALT7) adds galactose (G...
Beta-arrestin 1 and 2 (ARRB1 and 2) and the anterograde moto...
Beta-arrestins can serve as scaffolding molecules that facil...
Beta-catenin associates with the destruction complex through...
Beta-catenin increases IFN-beta expression by binding to the...
Beta-catenin is then phosphorylated at Ser33. Phosphorylated...
Beta-catenin is ubiquitinated by the SCF-B-TrCP1 complex.
Beta-catenin undergoes phosphorylation at Ser552 in a Lrrfip...
Beta-catenin:TCF-4 bound at the promoter of the GCG gene rec...
Beta-galactosidase (GLB1) can cleave terminal galactose resi...
Beta-galactosidase (GLB1) can cleave terminal galactose resi...
Beta-galactosidase can hydrolyse a galactose moeity from glo...
Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) tra...
Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) tra...
Beta-hexosaminidase (HEX) cleaves the terminal N-acetyl gala...
Beta-hexosaminidase (HEX) cleaves the terminal N-acetyl gala...
Beta-hexosaminidase A (bHEXA) cleaves the terminal N-acetyl ...
Beta-oxidation begins once fatty acids have been imported in...
Beta-Pix (Cool-1) associates with CBL, which appears to be a...
Beta-TrCP ubiquitinates p105 at several lysine residues with...
Beta-TrCP1 is an F-box type component of a particular SKP/CU...
Beta-tubulin folding intermediates generated via ATP-depende...
BetaKlotho (KLB) and heparan sulfate (HS) are required for f...
BH2 may compete with BH4 to bind eNOS, uncoupling eNOS leadi...
BH3-only proteins (tBid, BIM, PUMA, BAD, NOXA) associate wit...
BH4 donates an electron to the eNOS catalytic cycle and is o...
BH4 oxidation results in the radical BH3. which decays to 7,...
BID may promote cell death by activating BAX and BAK while i...
Biglycan (BGN) is a member of the small leucine-rich repeat ...
Biglycan is a member of the small leucine-rich repeat proteo...
Biglycan is a member of the small leucine-rich repeat proteo...
Bile acids are synthesised from cholesterol via two pathways...
Bilirubin (BIL) is a breakdown product of heme, causing deat...
Bilirubin (BIL) is a breakdown product of heme, causing deat...
Bilirubin (BIL) is a breakdown product of heme. Its accumula...
Bilirubin is the breakdown product of heme, causing death if...
BIM acts as a sentinel to check the integrity of the cytoske...
Binding and disruption of microbial membranes is widely beli...
Binding of a number of 'non-canonical' WNT ligands, notably ...
Binding of activated PKN1 to the androgen-activated AR (andr...
Binding of Activin AB or Activin B to the type II receptor A...
Binding of ankyrins is dependent on the phosphorylation and ...
Binding of ARL3 to UNC119B induces a conformational change t...
Binding of CaM to CAMK2 displaces the autoinhibitory loop fr...
Binding of CNTN1 to NOTCH2 results in release of the intrace...
Binding of DIABLO (SMAC) to the BIR2 domain of XIAP competes...
Binding of DIABLO (SMAC) to XIAP promotes the liberation of ...
Binding of DIABLO (SMAC) to XIAP promotes the release of cas...
Binding of DKK1 to LRP6 induces the clathrin-mediated endocy...
Binding of DNER to NOTCH1 induces gamma-secretase dependent ...
Binding of ERF to ETS2 promoter strongly represses ETS2 tran...
Binding of FOXa2/HNF3-beta to the 5'-flanking regions of the...
Binding of G beta gamma activates the GIRK/Kir3 channels tha...
Binding of Gab2 to tyrosine phosphorylated Shc promotes the ...
Binding of GHBP to GHR produces 'unproductive' dimers that p...
Binding of Glucagon-like peptide-1 to the Glucagon-like pept...
Binding of GOPC (also known as CAL, PIST or FIG) to CFTR (cy...
Binding of Hsp90 to the LIMK proteins protects them from deg...
Binding of ID1 to ETS2 inhibits ETS2-mediated activation of ...
Binding of IGF1 (IGF-I) or IGF2 (IGF-II) to the extracellula...
Binding of ligand to AGER results in the activation of multi...
Binding of ligand to the PTCH receptor activates the Hh sign...
Binding of NEDD4L promotes translocation of SMAD7 to the cyt...
Binding of Nodal to the Nodal receptor causes the type I com...
Binding of NOTCH1 to CNTN1 (contactin-1) is followed by gamm...
Binding of Notch1 to Cntn1 (contactin-1) was established by ...
Binding of NOTCH1 to DLL/JAG ligands expressed in the same c...
Binding of NRIF to p62 (Sequestosome) is suspected to modula...
Binding of p14-ARF to MDM2 decreases the half-life of MDM2, ...
Binding of PAK1, PAK2 or PAK3 to GTP-bound RAC1 or CDC42 dis...
Binding of Pdx1 to the 5'-flanking region of the IAPP gene w...
Binding of Pdx1 to the 5'-flanking region of the Insulin gen...
Binding of Pdx1 to the 5'-flanking region of the mouse Nkx6....
Binding of phosphorylated FOXM1 to CDC25A promoter stimulate...
Binding of PKN1 to androgen-activated AR (androgen receptor)...
Binding of PKN1, PKN2 or PKN3 to any of the RHO GTP-ases RHO...
Binding of Rac1 increases p21 activated kinases 1-3 (PAK1-3)...
Binding of RasGRF to Ca2+/Calmodulin in the presence of hig...
Binding of rhotekin (Rtkn) to Rho GTPases RhoA, RhoB and Rho...
Binding of SCF to KIT induces the activation and rapid incre...
Binding of Sema3A to the Neuropilin-1-Plexin-A receptor comp...
Binding of Syk causes conformational changes that lead to Sy...
Binding of TAB2 and TAB3 to K63-linked polyubiquitin chains ...
Binding of the AP-1 (JUN:FOS) subunit JUN to the KDM6B (JMJD...
Binding of the methionyl-tRNA initiator to the active eIF2:G...
Binding of the MTRF1L (MTRF1a) termination factor triggers h...
Binding of the NOTCH1 Coactivator Complex to the HES5 promot...
Binding of the NOTH1 Coactivator Complex to the MYC promoter...
Binding of the RAD51:RAD52 complex to ssDNA may provide nucl...
Binding of the SCF dimer to KIT rapidly triggers KIT dimeriz...
Binding of transducin (Gt) to activated rhodopsin (MII) prom...
Binding of transforming growth factor beta 1 (TGF beta 1, i....
Binding of VEGFA to VEGFR2 induces receptor dimerization and...
Binding of WNT5A to FZD receptors triggers the phosphorylati...
Binding of XP-C:RAD23B complex to the damaged site on the DN...
Binding of XPC complex to the damaged site on the DNA substr...
Biochemical and cellular studies have shown that the p101/p1...
Biochemical characterization of purified avian PPAT (chicken...
Biochemical characterization of purified avian PPAT (chicken...
Biochemical studies of rat and bovine liver extracts suggest...
Biogenesis of microRNAs (miRNAs) can be summarized in five s...
Bioinformatics analysis of the chicken genome revealed a pat...
Biological processes are captured in Reactome by identifying...
Biosynthesis of mycothiol starts from glucose-6-phosphate an...
Biotin (Btn) acts as a coenzyme for 5 carboxylases that exis...
Biotin (Btn) acts as a coenzyme for 5 carboxylases that exis...
Biotin (Btn) acts as a coenzyme for 5 carboxylases that exis...
Biotin (Btn) acts as a coenzyme to 4 carboxylases which exis...
Biotin (Btn) acts as a coenzyme to 4 carboxylases which exis...
Biotin (Btn) acts as a coenzyme to 4 carboxylases which exis...
Biotin (Btn) is an essential cofactor in a variety of carbox...
Biotin (Btn, vitamin B7, vitamin H, coenzyme R) is an essent...
Biotin (vitamin H or B7) is a water-soluble B-complex vitami...
BiP is a chaperone which binds unfolded proteins as well as ...
BK channels (also called Maxi-K or slo1) are potassium ion c...
BLM is SUMOylated at lysine-317, lysine-331, lysine-344, and...
BLNK (SLP-65, BASH) forms a stable complex with GRB2, SOS1, ...
BMAL1 (ARNTL) contains both a nuclear localization signal an...
BMAL1 (ARNTL), CLOCK, and NPAS2 are basic helix-loop-helix t...
Bmal1 (Arntl), Clock, and Npas2 are basic helix-loop-helix t...
Bmal1 (Arntl), Clock, and Npas2 are phosphorylated by unknow...
Bmal1:Clock (Arntl:Clock) and Bmal1:Npas2 (Arntl:Npas2) hete...
Bmal1:Clock (Arntl:Clock) and Bmal1:Npas2 (Arntl:Npas2) hete...
Bmal1:Clock (Arntl:Clock) and Bmal1:Npas2 (Arntl:Npas2) hete...
Bmal1:Clock (Arntl:Clock) and Bmal1:Npas2 (Arntl:Npas2) hete...
Bmal1:Clock (Arntl:Clock) and Bmal1:Npas2 (Arntl:Npas2) hete...
Bmal1:Clock (Arntl:Clock) and Bmal1:Npas2 (Arntl:Npas2) hete...
Bmal1:Clock (Arntl:Clock) heterodimers bind an E-box enhance...
Bmal1:Clock (Arntl:Clock) heterodimers bind E-boxes in the p...
Bmal1:Clock (Arntl:Clock) heterodimers bind E-boxes in the p...
Bmal1:Clock (Arntl:Clock) heterodimers bind E-boxes in the p...
BMAL1:CLOCK (ARNTL:CLOCK) heterodimers bind E-boxes in the p...
Bmal1:Clock (Arntl:Clock) heterodimers bind E-boxes in the s...
BMAL2 (ARNTL2, CLIF) forms a heterodimer with CLOCK, binds E...
BMP ligand traps are cystine-knot containing proteins which ...
BMP receptors, unlike TGF-beta receptors are known to form h...
Bnip-2 interacts with Cdc42 through its Bnip-2 and Cdc42GAP ...
Bnip-2 is a scaffold protein with a single recognizable moti...
Boc is a co-receptor for Hh signaling that binds both to Ptc...
Bombesin-like receptors are widely distributed in the CNS as...
Bone morphogenetic protein-1 (BMP1) cleaves the C-terminal p...
Bone sialoprotein 2 (Ibsp) is an anionic phosphorylated glyc...
Bone sialoprotein 2 (IBSP) is an anionic phosphorylated glyc...
BORA is able to interact with both AURKA (Aurora A kinase) a...
Both BDNF and NGF treatment recruits clathrin and AP2 (adapt...
Both CLEC7A (Dectin-1) and CD209 (DC-SIGN) modulates Toll-li...
Both DHX36 and DHX9 were found to interact with MyD88 when c...
Both ETS1 and ETS2 contain a consensus site (PLLTP) for MAPK...
Both Follistatin (FST) and Follistatin-like-3 (FSTL3) irreve...
Both hemoglobin and the cytosolic face of erythrocytes are a...
Both IRAK1 and IRAK4 were shown to phosphorylate Pellino iso...
Both mannose-binding lectin (MBL) and ficolins are lectins, ...
Both mature neurotrophin and pro-neurotrophin are released e...
Both MTRF1L and ICT1 can bind a standard stop codon in the A...
Both p53-independent and p53-dependent mechanisms of inducti...
Both PRC (PPRC1) and NRF2 bind HCF1 (Vercauteren et al. 2008...
Both Pregnancy Associated Plasma Protein A (PAPP-A) and A2 (...
Both the full-length receptor and cleaved fragment correspon...
Both unphosphorylated and phosphorylated Stat3 can form dime...
Botulinum toxin type A (BoNT/A), a disulfide bonded heavy ch...
Botulinum toxin type A light chain (BoNT/A LC), in the cytos...
Botulinum toxin type B (BoNT/B), a disulfide-bonded heavy ch...
Botulinum toxin type B light chain (BoNT/B LC), in the cytos...
Botulinum toxin type C (BoNT/C) is only very rarely associat...
Botulinum toxin type C light chain (BoNT/C LC), in the cytos...
Botulinum toxin type C light chain (BoNT/C LC), in the cytos...
Botulinum toxin type D (BoNT/D) is only very rarely associat...
Botulinum toxin type D light chain (BoNT/D LC), in the cytos...
Botulinum toxin type D light chain (BoNT/D LC), in the cytos...
Botulinum toxin type E (BoNT/E), a disulfide-bonded heavy ch...
Botulinum toxin type E light chain (BoNT/E LC), in the cytos...
Botulinum toxin type F (BoNT/F) is only very rarely associat...
Botulinum toxin type F light chain (BoNT/F LC), in the cytos...
Botulinum toxin type F light chain (BoNT/F LC), in the cytos...
Botulinum toxin type G (BoNT/G) is rarely if ever associated...
Botulinum toxin type G light chain (BoNT/G LC), in the cytos...
Botulinum toxin type G light chain (BoNT/G LC), in the cytos...
Bovine studies (Beharry et al. 2004) have indicated NRPE to ...
Bovine studies (Beharry et al. 2004) have indicated NRPE to ...
BP180 interacts with Plectin following the association of Pl...
BP230 interacts with cytokeratins K5/K14 (Fontao et al., 2...
Bradykinin (Rocha e Silva M, et al, 1949) is a 9 amino-acid ...
Branch migration or strand exchange occurs as the compliment...
BRCA1 localizes to axial elements of the synaptonemal comple...
BRCA1 phosphorylation occurs at multiple sites by ATM and is...
BRCA2 and RAD51 interact directly through the highly conserv...
BRCA2 plays a critical role in the initiation of DNA repair ...
Brevican, a member of the lectican family, is one of the mos...
Brevican, a member of the lectican family, is one of the mos...
BRF1 binds AU-rich elements in the following mRNAs: IL-3, CS...
BRF1 is phosphorylated at Serine92 and Serine203 by Protein ...
BRF1 recruits RNA degradation activities to hydrolyze the RN...
BRIP1 (also called BACH1) is a DEAH helicase that interacts ...
BRIP1, a DNA helicase also known as FANCJ, provides evidence...
Brivanib alaninate is the pro-drug of brivanib, a VEGFR- and...
Brivanib, from Bristol Myers Squibb, is an FGFR and VEGFR in...
Bruton's tyrosine kinase (BTK) is a cytoplasmic protein tyro...
BSG (CD147, EMMPRIN) is a glycoprotein, enriched on the surf...
BTD deficiency is an autosomal recessive disorder in which t...
BTK/ITK are activated in a two step model. In the first step...
Budding vesicles loaded with the nonameric complex bud off f...
Butyrate response factor 1 (BRF1) binds AU-rich elements in ...
Butyrate Response Factor 1 (BRF1, ZFP36L1, not to be confuse...
By analogy to the activity of its experimentally characteriz...
By analogy to the process described for botulinum toxin type...
By analogy to the process described for botulinum toxin type...
By analogy to the process described for botulinum toxin type...
By analogy to the process described for botulinum toxin type...
By analogy to the process described for botulinum toxin type...
By analogy to the process described for botulinum toxin type...
By analogy to the well-studied chicken system, L1 can be coe...
By analogy to the well-studied chicken system, L1 heterophil...
By analogy with adenylyl cyclases I and II, adenylyl cyclase...
By analogy with the wild-type pathway, PLC-gamma is presumed...
By analogy with yeast Hfs1, human NFS1 probably has an N-ter...
By applying the chromatin immunoprecipitation technique to p...
By co-culturing two cell lines, one expressing recombinant r...
By expressing exogenous recombinant mouse Notch1, Numb and I...
By expressing membrane bound mouse Notch1 construct NdeltaE ...
By expressing mouse Notch2deltaE recombinant protein, which ...
By expressing myc-tagged full length recombinant mouse Notch...
By homology with CD79A (Ig-alpha), CD79B (Ig-beta) is presum...
By homology with human Beta-TrCP1, mouse Beta-TrCP (Btrc) is...
c-Abl is a ubiquitously-expressed non-receptor tyrosine kina...
c-FLIP proteins (CASP8 and FADD-like apoptosis regulators or...
c-IAP1 is cleaved by caspase-3 producing a proapoptotic C-te...
c-Jun NH2 terminal kinase (JNK) plays a role in conveying si...
C-Jun NH2 terminal kinases (JNKs) are an evolutionarily cons...
C-Jun NH2 terminal kinases are stress activated MAPKs, also ...
c-Src binds to Raf1, the interaction involves the SH2 and S...
c-src has been shown to interact with Cx43 (Giepmans et al.,...
c-Src phosphorylates Cx43 on Tyr 265.
C/EBPalpha (CEBPA) binds the promoter of the Adiponectin gen...
C/EBPalpha (CEBPA) binds the promoter of the Ob gene encodin...
C/EBPbeta (CEBPB) binds the promoter of the Adiponectin gene...
C1 activation requires interaction with two separate Fc doma...
C1 complex undergoes conformational changes which result in ...
C1 is a calcium-dependent complex of C1q, R and S in the mol...
C1, the first component of complement is a complex containin...
C2 binds to surface-bound C4b to form the C4b:C2 complex, wh...
C2 domain-containing protein 3 (C2CD3) is basal body-localiz...
C2 is cleaved into the large C2a and the small C2b fragment....
C2CD3 and the centrosome component OFD1 are required for the...
C2CD3 and the distal appendage protein CEP164 are required f...
C3(H2O):Factor Bb is a C3 convertase, sometimes referred to ...
C3b molecules are continuously deposited onto target surface...
C3b on a surface binds Factor B from solution to form a comp...
C3b, a product of the enzymatic action of C3 convertases on ...
C3b:Bb is naturally labile with a half-life of ~90 s. unless...
C3b:Bb is naturally labile with a half-life of ~90 s; associ...
C3G is a guanine nucleotide exchange factor for Rap1, which ...
C4 alpha chain has a thioester bond between Cys 1010 and Gln...
C4 binding protein accelerates the decay of C4bC2a in a dose...
C4 binding protein accelerates the decay of C4bC2a in a dose...
C4 is cleaved by activated protease C1s in the classical pat...
C4b and C2a bind to form the classical pathway C3-convertase...
C4b and C2a form a complex termed the classical pathway C3 c...
C4b and C3b are opsonins, which are able to bind covalently ...
C4b binding to the target surface is regulated by a hydrolys...
C4b-binding protein is a cofactor for Complement Factor I, a...
C4b-binding protein is a cofactor in Factor I mediated C4b p...
C5 convertases are serine proteases that cleave C5 with high...
C5 convertases are serine proteases that cleave complement C...
C5a (Fernandez HN and Hugli TE, 1978) is a protein fragment ...
Ca2+ activated potassium channels are expressed in neuronal ...
Ca2+ fluxes through NMDA receptors in the post-synaptic neur...
Ca2+ homeostasis is controlled by processes that elevate or ...
Ca2+ influx from the extracellular space into the presynapti...
Ca2+ influx through the NMDA receptor initiates subsequent m...
Ca2+ influx through the NMDA receptor leads to the activatio...
Ca2+ signal generated through NMDA receptor in the post-syna...
Cadherins are the major cell adhesion molecules at adherens ...
Caffeine is one of the world's most frequently consumed xeno...
Calcineurin (CaN), also called protein phosphatase 2B (PP2B)...
Calcineurin dephosposphrylates multiple residues on Nfat2 wh...
Calcineurin has been identified as a Ca2+- and calmodulin-de...
Calcineurin, the Ca2+ activated protein phosphatase, dephosp...
Calcitriol (1,25(OH)2-D3) is biologically inactivated throug...
Calcium (Ca2+) can be mobilised from intracellular stores by...
Calcium activates calcineurin in two ways: binding the regul...
Calcium and DAG regulated guanine nucleotide exchange factor...
Calcium binds to Calmodulin
Calcium ions are used by cells as ubiquitous signalling mole...
Calcium is released from the ER to the cytosol upon IP3 rece...
Calcium release in response to WNT5A has been shown to activ...
Calcium, as the ion Ca2+, is essential in many biological pr...
Calcium-activated chloride channel regulators 1,2,3P and 4 (...
Calcium-activated chloride channels (CaCCs) are ubiquitously...
Caldesmon functions in an analogous fashion to troponin in s...
Calmodulin (CaM) is a small acidic protein that contains fou...
Calnexin (membrane protein) and calreticulin (soluble in ER)...
CaMKII gets activated upon Ca2+ influx through the NMDA rece...
CaMKII is an important regulator of neuronal plasticity. CaM...
CaMKII is composed of a homo or hetero dodecamer of four sub...
CaMKII is fully activated upon Ca2+/Calmodulin binding. In a...
CaMKIV becomes fully activated after a three-step mechanism:...
CaMKIV is activated in a multi-step mechanism in an Ca2+/Cal...
CaMKK is fully activated upon binding Ca2+/Calmodulin after ...
cAMP is a known regulator of PKA activity and works by bindi...
cAMP is generated by the action of adenylate cyclases (revie...
cAMP selective hydrolase
cAMP-dependent protein kinase A (PKA) phosphorylates in vitr...
Can hydrolyze both cAMP and cGMP
Canstatin is the non-collagenous C-terminal domain of alpha...
Capped, synthesized RNA strand complementary to vRNA, plus v...
Carbohydrate is a major component of the human diet, and inc...
Carbohydrate sulfotransferase 1 (CHST1, keratan sulfate Gal-...
Carbohydrate sulfotransferase 14 (CHST14 also known as D4ST-...
Carbohydrate sulfotransferase 14 (CHST14) (Evers et al. 2001...
Carbohydrate sulfotransferase 15 (CHST15) catalyses the tran...
Carbohydrate sulfotransferase 3 (CHST3 also known as C6ST-1)...
Carbohydrate sulfotransferase 3 (CHST3) transfers sulfate (S...
Carbohydrate sulfotransferase 6 (CHST6) catalyzes the transf...
Carbohydrate sulfotransferase 6 (CHST6) catalyzes the transf...
Carbohydrate sulfotransferase9, 11, 12 and 13 (CHST9, 11, 12...
Carbohydrate sulfotransferases 2, 5 and 6 (CHST2, 5 and 6) c...
Carbon dioxide (CO2) in plasma is hydrated to yield protons ...
Carbon tetrachloride (CCl4) has been widely used as a dry-cl...
Carbonic anhydrase I (CA1, Khalifah 1971, Pesando 1975, Simo...
Carbonic anhydrase I (CA1, Khalifah 1971, Simonsson et al. 1...
Carbonic anhydrase I (CA1, Khalifah 1971, Simonsson et al. 1...
Carbonic anhydrase IV (CA4) anchored to extracellular face o...
Carbonic anhydrase IV (CA4) located on the extracellular fac...
Carbonic anhydrase IV (CA4, Zhu and Sly 1990, Okuyama et al....
Carbonic anhydrase IV (CA4, Zhu and Sly 1990, Okuyama et al....
Carbonic anhydrase VA (CA5A, Nagao et al. 1993, Franchi et a...
Carbonic anhydrase VA (CA5A, Nagao et al. 1993, Franchi et a...
Carbonic anhydrase VI (CA6) dehydrates bicarbonate to yield ...
Carbonic anhydrase VI (CA6) hydrates carbon dioxide to yield...
Carbonic anhydrases reversibly catalyze the hydration of car...
Carbonyl reductase (CBR1) aka prostaglandin 9-keto reductase...
Carboxylation of acetyl-CoA and decarboxylation of malonyl-C...
Carboxymycobactin and mycobactin exchange their iron loads. ...
Carboxymycobactin is the more polar siderophore of Mtb
CARD interactions between CARD9 and BCL10 induce BCL10 oligo...
CARD9 binds RIP2 and NOD2. In addition overexpression of CAR...
Cardiolipin (CL) transports via membrane contact sites betwe...
Cardiolipin(CL) is synthesized in the inner mitochondrial me...
Cargo must pass through the various compartments of the Golg...
CARMA1 (CARD11/Caspase recruitment domain-containing protein...
CARMA1 and Bcl10 are the possible link between PKC theta and...
CARMA1 is phosphorylated and recruits BCL10 and MALT1 to the...
CARMA1 is phosphorylated at serines 559, 644, and 652 by Pro...
CARMA1 is phosphorylated by PKC-beta and recruits TAK1 and t...
CARMA1 phosphorylation initiates its oligomerization and the...
Carnitine is synthesized in four steps from trimethyllysine ...
Carnitine palmitoyl transferase 1 (CPT1) associated with the...
Carrier-mediated urea transport allows rapid urea movement a...
CARS (cytosolic cysteinyl tRNA synthetase) catalyzes the rea...
CARS2 (mitochondrial cysteinyl tRNA synthetase) catalyzes th...
Cartilage oligomeric matrix protein (COMP, thrombospondin-5)...
Cartilage oligomeric matrix protein (COMP, thrombospondin-5)...
CASK is a scaffolding protein that participates in maintenan...
Caspase 1 is expressed as a precursor that is cleaved to gen...
Caspase mediated cleavage of desmoglein 1 leads to decreased...
Caspase mediated cleavage produces a constitutively active k...
Caspase-10 precursor is recruited to the TRAIL:TRAIL recepto...
Caspase-3 (Steinhusen et al. 2001) and calpain-1 (Rios-Doria...
Caspase-3 cleaves DFF45 between residues 224,225.
Caspase-3 cleaves Tau at position 421 in vitro producing an ...
Caspase-3 cleaves the DFF45 subunit of the DFF45:DFF40 compl...
Caspase-3-mediated cleavage of ROCK I induces MLC phosphoryl...
Caspase-8 mediated cleavage of BAP31 at the ER produces a ...
Caspase-8 (casp-8) and caspase-10 (casp-10) are involved in ...
Caspase-8 is synthesized as zymogen (procaspase-8) and is fo...
Caspase-8 precursor (Pro-Caspase-8, also known as MACH) bind...
Caspase-8 zymogens are present in the cells as inactive mono...
Caspase-8-precursor (pro-caspase-8) binds TRAF2:TRADD:RIP1:F...
Caspase-9 is activated in an ATP-dependent manner following ...
Caspase-mediated cleavage of a number of proteins in the co...
Caspase-mediated cleavage of Mst3 activates its intrinsic ki...
Caspases initiate the destruction of the nucleus cleavage of...
Caspases initiate the destruction of the nucleus cleavage of...
Caspases-3 and -7 are directly cleaved downstream of caspase...
Catabolic inactivation of the active, hormonal form of vitam...
Catabolic inactivation of the active, hormonal form of vitam...
Catabolic inactivation of the active, hormonal form of vitam...
Catabolite repression protein Cat5 aka ubiquinone biosynthes...
Catalytic subunit p110 of PI3K (PIK3CA) is recruited by the ...
Catalytic subunit p110 of PI3K (PIK3CA) is recruited by the ...
Catalyzed by the RNA polymerase activity of the viral PB1 su...
Catecholamines and thyroxine are synthesized from tyrosine, ...
Cathepsin G cleaves IGFBP-3 between amino acids 168 and 169 ...
Cathepsin G hydrolyzes angiotensin-(1-10) (angiotensin I) to...
Cathepsin Z (cathepsin X) hydrolyzes angiotensin-(1-10) (ang...
CatSper (CATionic channel of SPERm), a pH regulated, princip...
Caveolin inhibition of eNOS is relieved by calmodulin, which...
Caveolin-1 is the primary negative regulatory protein for eN...
Cbl and Vav interact in thymocytes and peripheral T cells (M...
Cbl binds B-cell linker protein, a molecular scaffold bridgi...
CBL binds multiple signalling proteins including GRB2. The C...
CBL binds to phosphorylated tyrosine Y1045 residue of EGFR c...
CBL down-regulates receptor tyrosine kinases by conjugating ...
Cbl has been identified in ternary complexes with CRKL and C...
Cbl is an E3 ubiquitin-protein ligase that negatively regula...
Cbl is an E3 ubiquitin-protein ligase that negatively regula...
Cbl is constitutively associated with Grb2 in resting hemato...
Cbl is tyrosine phosphorylated following stimulation with IL...
CBL neddylates TGFBR2 on lysine residues K556 and K567. The ...
CBl-CIN85-Endophilin complex mediates ligand-induced down-re...
CBP (CREB-binding protein) and the closely related p300 are ...
CBX4 (Pc2) in the PRC1 complex SUMOylates CETN2 at an unknow...
CBY1 contains both NLS and NES sequences and continuously sh...
CBY1 is phosphorylated in vitro at serine 20 by AKT1 and AKT...
CC binding protein 2 (CCBP2) is a promiscuous chemokine rece...
CCBL1 (KAT 1) catalyzes the reaction of glutamine and pyruva...
CCBL1 (KAT 1) catalyzes the reaction of kynurenine and pyruv...
CCBL1 (KAT 1) catalyzes the reaction of phenylalanine and py...
CCBL2 (KAT 3) catalyzes the reaction of kynurenine and pyruv...
CCDC88C was identified as Dapple in a screen of mouse brain ...
Ccdc88c was identified as Dapple in a screen of mouse brain ...
CCND1 (cyclin D1) forms a complex with CREBBP and binds to t...
CCP110 is a negative regulator of ciliogenesis that caps the...
CCR10 (previously known as GPR2) (Jarmin DI et al, 2000) is ...
CCR11 binds CCL19, CCL21, and CCL25 but calcium signalling i...
CCR6 (Baba M et al, 1997) is expressed on inactive memory T-...
CCR7 (Epstein-Barr virus-induced gene 1, EBI1) (Birkenbach M...
CCR9 (previously called orphan receptor GPR 9-6) is highly e...
CCRL2 binds the chemokine CCL19 with an affinity similar to ...
CCT/TRiC facilitates folding of newly translated SK1 into it...
CD14, a GPI-anchored molecule found on the cell surface of h...
CD151 interacts with the extracellular domain of the integr...
CD160 is a GPI-anchored lymphocyte surface receptor in which...
CD177 is a 58- to 64-kDa glycosylphosphatidylinositol-anchor...
CD19 is a lymphocyte cell surface molecule that functions as...
CD2, CD48, CD84, CD244 and CD58 have a similar extracellular...
CD2-associated protein (CD2AP) is an adapter molecule of the...
CD209 (also called as DC-SIGN (DC-specific intracellular adh...
CD209 (DC-SIGN) acts as an adhesion molecule and besides for...
CD209 (DC-SIGN) interacts with pathogens through either mann...
CD28 binds to several intracellular proteins including PI3 k...
CD28 delivers the costimulatory signal by interacting with i...
CD28 is capable of binding the Src homology 3 (SH3) domains ...
CD36 (Platelet glycoprotein IV) binds oxidized LDL (Janabi e...
Cd36 (Platelet glycoprotein IV) binds oxidized LDL, beta-glu...
CD4 is degraded
CD4 is ubiquitinated in the CD4:Vpu–h-βTrCP:Skp1 complex.
CD4, located on the host cell membrane, is the main cellular...
CD40 is a member of the Tumour Necrosis Factor receptor fami...
CD43, a major leukocyte cell surface sialoglycoprotein, inte...
CD47 is an extracellular ligand for SIRP alpha. SIRP alpha d...
CD55 (or Decay Accelerating Factor; DAF) is a member of the ...
CD59, the major inhibitor of the complement membrane attack ...
CD84 is a homophilic receptor expressed on T cells, B cells,...
CD97hc is a multifunctional glycoprotein with a single trans...
Cdc25A dephosphorylates Cdk2 and activates cyclin E-Cdk2 and...
cdc25A protein is degraded by the ubiquitin-proteasome machi...
Cdc25A, and probably Cdc25B, regulate the entry into S phase...
Cdc25B shuttles between the nucleus and the cytoplasm. Trans...
Cdc25C is negatively regulated by phosphorylation on Ser 21...
Cdc25C is phosphorylated by Chk1 at ser-216 (Blasina et al.,...
CDC42 is involved in the formation of filopodia with potenti...
Cdc6 is a regulator of DNA replication initiation in both ye...
CDCA5 (Sororin) is essential for the establishment of sister...
CDCA5 (Sororin) is essential for the establishment of sister...
Cdh1 (FZR1) is able to bind both G9a (EHMT2) and GLP (EHMT1)...
Cdh1 is multiubiquitinated by the APC/C:Cdh1 complex prior t...
Cdh1:APC/C complex, stabilized by the DNA damage-induced ATM...
Cdk mediated phosphorylation of Emi1 is believed to promotes...
Cdk-9 is the kinase subunit of P-TEFb that phosphorylates Se...
CDK1 (CDC2) in complex with CCNB (cyclin B) phosphorylates c...
Cdk1 (Cdc2) in complex with Ccnb (cyclin B) phosphorylates c...
CDK1 activity promotes the nuclear pore complex (NPC) disass...
CDK1 phosphorylates both human and Drosophila BORA protein (...
CDK1-mediated phosphorylation of GORASP1 (GRASP65) enables G...
CDK11p58 is a kinase that is active during mitosis when it a...
CDK5 and ABL1 enzyme substrate 1 (Cables1) is a negative reg...
CDK5 and ABL1 enzyme substrate 1 (Cables1) is a negative reg...
Cdk5:p35 complex is associated with Plexin-A through the act...
CDK8 in complex with cyclin C (CDK8:CCNC) and CDK9 in comple...
CDK8 phosphorylates conserved serine residues in the TAD and...
CDKN1A (p21) is transcriptionally activated by TP53 (p53) af...
CDKN2A (p14-ARF) SUMOylates WRN at lysine-356, lysine-496, a...
CDO and BOC form complexes in a cis fashion via association ...
CDO selectively binds to neogenin in a cis fashion and this ...
CDO/Cdon (cell-adhesion-molecule-related/downregulated by on...
CDON is a transmembrane glycoprotein that binds directly to ...
Cebpb binds the promoter of the Ebf1 gene and activates tran...
Cebpd binds the promoter of the Ebf1 gene and activates tran...
CEL (bile salt-dependent lipase) catalyzes the hydrolysis of...
CEL (bile salt-dependent lipase) catalyzes the hydrolysis of...
Cell cycle progression is regulated by cyclin-dependent prot...
Cell cycle proteins mulitubiquitinated by the APC/C are targ...
Cell death is a fundamental cellular response that has a cru...
Cell death triggered by extrinsic stimuli via death receptor...
Cell stimulation with viral ds RNA leads to the activation o...
Cell surface levels of GHR are the primary determinant of GH...
Cell survival and growth are also promoted by AKT phosphoryl...
Cell-extracellular matrix (ECM) interactions play a critical...
Cell-to-Cell communication is crucial for multicellular orga...
Cells are subject to external molecular and physical stresse...
Cells exposed to castanospermine or 1-deoxynojirimycin (inhi...
Cells take up glucose by facilitated diffusion, via glucose ...
Cellular DNA is susceptible to different types of cytotoxic ...
Cellular inhibitor of apoptosis proteins (BIRC2, BIRC3 also ...
Cellular insults causing DNA damage can be of varied origins...
Cellular metabolic processes generate energy through the oxi...
Cellular retinaldehyde-binding protein (RLBP1, CRALBP) (Intr...
Cellular retinoic acid-binding protein 2 (CRABP2) is a cytos...
Cellular senescence involves irreversible growth arrest acco...
Centrosomal abnormalities are frequently observed in cancers...
Ceramide glucosyltransferase (UGCG) catalyses the first glyc...
Ceramide kinase (CERK) mediates the phosphorylation of ceram...
Ceramide-1-phosphate transfer protein (GLTPD1) mediates the ...
Cerberus binds Xnr-1, the Xenopus Nodal homolog, and negativ...
CERBERUS forms heterodimers with NODAL, preventing NODAL fro...
CERT (ceramide transfer protein), an isoform of COL4A3BP, me...
Certain fibril-associated collagens with interrupted triple ...
Certain fibril-associated collagens with interrupted triple ...
Certain mouse pathways have been fully manually curated in R...
Certain normally extracellular MMPs can transiently localize...
CETP (cholesterol ester transfer protein) complexed with cho...
CETP (cholesterol ester transfer protein) complexed with tri...
Cetuximab binds to the extracellular domain of EGFR and bloc...
CF I, which appears to be composed of two subunits, one of s...
cGMP and cAMP dependent protein kinases (PKG and PKA respect...
cGMP selective hydrolase
Changes in gene expression are required for the T cell to ga...
CHD8 is a ATP-dependent chromatin remodeling factor that bin...
CHE1, also named AATF, is an Apoptosis Antagonizing Transcri...
Chemical synapses are specialized junctions that are used fo...
Chemokine receptors are cytokine receptors found on the surf...
Chenodeoxycholoyl CoA reacts with glycine or taurine to form...
Chibby (CBY1) is a conserved 126 amino acid protein that act...
Chicken and human telomeres share many features including th...
Chicken B lymphocyte precursors and DT40 cells diversify the...
Chicken CD14 was reported to be involved in chicken TLR4 act...
chicken complement factor D is annotated as a hypothetical p...
Chicken DT40 cells lacking FANCG (one of the proteins of the...
Chicken ERK2 shares 99% of amino acid sequence identity with...
Chicken IKK epsilon protein, confirmed by transcript evidede...
Chicken IRAK4 shows 66% amino acid identity to human IRAK4. ...
Chicken NFkB p105 (precursor of p50) subunit and NFkB p65 su...
Chicken RIP1 protein, confirmed by transcript evidedence, sh...
Chicken SNM1A (DNA cross-link repair 1A protein) is not epis...
Chicken TAK1 complex proteins TAK1, TAB1, TAB2 and TAB3, con...
Chicken TBK1 protein, confirmed by transcript evidedence, sh...
Chicken TICAM1 encodes a 735 amino-acid protein that shares ...
Chicken TLR21 was demonstrated to use a MyD88-dependent pat...
Chicken TLR21 was shown to respond to both bacterial chromos...
Chicken TRAF6 protein, confirmed by transcript evidence, sho...
Chickens express TLR21 which is absent in human; chTLR21 has...
ChIP studies in HEK293 cells show that RUVBL1(TIP49), TRRAP,...
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1)...
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1)...
Chk1 directly phosphorylates Cdc25A at Ser-123. Chk1 phospho...
Chk1 is a checkpoint kinase activated during genotoxic stres...
Chk1 phosphorylation on Ser-345 is mediated by ATR kinase up...
Chk2 phosphorylation by ATM requires NBS1 following DSB form...
CHL1 accumulates in the presynaptic plasma membrane and it r...
CHL1 associates with the sub-membranous actin cytoskeleton t...
CHL1 binds the Sema3A receptor, Neuropilin-1 (NP-1), via a c...
CHL1 interacts with alpha1beta1/alpha2beta1 integrins in cis...
Chloride channel 7 comprises H+/Cl- exchange transporter 7 (...
Chloride channel proteins 1, 2, Ka and Kb (CLCN1, 2, KA, KB)...
Cholate is translocated from the peroxisomal matrix to the c...
Cholate or chenodeoxycholate, coenzyme A, and ATP react to f...
Cholecystokinin (CCK, previously called pancreozymin) (Takah...
Cholest-5-ene-3beta,7alpha,24(S)-triol and NAD+ react to for...
Cholest-5-ene-3beta,7alpha,27-triol and NAD+ react to form 4...
Cholesta-5,7,24-trien-3beta-ol and NADPH + H+ react to form ...
Cholesta-7,24-dien-3beta-ol, NADPH + H+, and O2 react to for...
Cholesterol 24-hydroxylase (CYP46A1), an enzyme associated w...
Cholesterol and NADPH + H+ react to form 22beta-hydroxychole...
Cholesterol and palmitoyl-modification of Hh-Np render the l...
Cholesterol CHOL), NADPH + H+, and O2 react to form 27-hydro...
Cholesterol is released from its complex with STAR in the mi...
Cholesterol is synthesized de novo from from acetyl CoA. The...
Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11...
Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11...
Cholesterol traverses the cytosol and the mitochondrial inte...
Cholesterol, NADPH + H+, and O2 form 7alpha-cholesterol (5-c...
Choline (Cho) transports from the extracellular space throug...
Choloyl CoA reacts with glycine or taurine to form glycochol...
Choloyl-CoA and water react to form cholate and CoASH. This ...
Chondroitin sulfate (CS) glycosaminoglycan consists of N-ace...
Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GA...
Chondroitin sulfate (CS) is hydrolysed from its chondroitin ...
Chondroitin sulfate N-acetylgalactosaminyltransferases 1 and...
Chondroitin sulfate synthase 1 (CHSY1) (Kitagawa et al. 2001...
Chondroitin sulfate synthase 1 (CHSY1) (Kitagawa et al. 2001...
Chondroitin sulfate synthases (CHSY) are involved in the syn...
ChREBP (Carbohydrate Response Element Binding Protein) doubl...
ChREBP (Carbohydrate Response Element Binding Protein) is a ...
Chromatin loading of the proliferating cell nuclear antigen ...
Chromatin organization refers to the composition and conform...
Chromobox (CBX) genes encode members of the Heterochromatin ...
Chromokinesins consist of the kinesin-4 and kinesin-10 famil...
Chromosomal aberrations involving nuclear receptor coactivat...
Chromosome maintenance is critical for stable chromosome fun...
Chylomicron micron remnants containing apolipoprotein E asso...
Chylomicron remnants (CRs) are "sieved" when they arrive at ...
Chylomicron remnants (CRs) are "sieved" when they arrive at ...
Chylomicrons (CM) are large (75–450 nm), spherical lipoprote...
Chylomicrons transport triacylglycerol, phospholipid, and ch...
Chymase hydrolyzes angiotensin-(1-10) (angiotensin) to yield...
Cilia are enriched in acetylated tubulin, a marker that is a...
Ciliary localization of the alternative kinesin-2 motor KIF1...
Circulates in blood as a disulfide-linked trimer of an alpha...
Circulating nascent chylomicrons acquire copies of apolipopr...
CIT-3 (CIT-N, citron-N or citron) is a splicing isoform of C...
CIT-3 (CIT-N, Citron-N, Citron) is the splice isoform of CIT...
Citron kinase (CIT) or citron RHO-interacting kinase (CRIK) ...
Citron kinase CIT was identified as a RHO GTPase effector in...
CK1a binds to Axin and phosphorylates beta-catenin at Ser45 ...
CKII phosphorylates L1CAM at serine 1181, just after the AP-...
CLASP acts positively downstream of Abl as part of the repel...
Claspin is a replication fork-associated protein important f...
Claspin is cleaved by caspase-7 during the initiation of apo...
Claspin is loaded onto DNA replication origins during replic...
Class 2 myosins are a set of protein complexes that bind act...
Class A scavenger receptors contain an intracellular domain,...
Class B receptors have two transmembrane domains separated b...
Class I Phosphoinositide 3-kinases (PI3Ks) are heterodimeric...
Class IA PI3K is a heterodimer of a p85 regulatory subunit (...
Class II facilitative transporters consist of GLUT5, 7, 9 an...
Class III facilitative transporters consist of five members;...
Classical Kir channels are inwardly rectifying K+ channels w...
Classical models of GHR activation suggest that GH binds seq...
Clathrin-coated vesicles (CCVs) originating from the trans-G...
Claudin-1 takes part in homophilic interactions at tight ju...
Claudins are the major cell adhesion molecules in tight junc...
Cleavage by PIWI proteins yields RNAs with a 5' phosphate an...
Cleavage of a single peptide bond converts factor XII to act...
Cleavage of APC by caspase 3 and release of the amino-term...
Cleavage of C4 exposes a highly reactive thioester bond on t...
Cleavage of C4 exposes an active thioester bond on the large...
Cleavage of C5 by C5 convertases is the last enzymatic step ...
Cleavage of desmosomal proteins including desmoplakin contri...
Cleavage of Etk by caspase-3 stimulates its kinase activity....
Cleavage of factor VIII light chain promotes a change in the...
Cleavage of fringe-modified NOTCH by FURIN has not been exam...
Cleavage of Gas2 during apoptosis is associated with changes...
Cleavage of mouse Notch1 at the S2 site precedes the gamma-s...
Cleavage of PKCtheta by Caspase-3 induces nuclear fragmenta...
Cleavage of the Asn66-Leu67 bond of MMP2 activates it suffic...
Cleavage of the C-terminal cytoplasmic domain of occludin d...
Cleaved Satb1 dissociates from chromatin and may function i...
Cleaving the Asn66-Leu67 bond of MMP2 activates it sufficien...
CLEC4A (C-type lectin domain family 4 member A/Dendritic cel...
CLEC4C (C-type lectin domain family 4 member C/Blood dendrit...
CLEC4D (Macrophage C-type lectin (MCL)) is a member of the C...
CLEC4E (also called Mincle or CLECSF9) is a C-type lectin re...
CLEC6A (C-type lectin domain family 6 member A/Dectin-2 (Den...
CLEC7A (also known as Dectin-1) is a pattern-recognition rec...
CLEC7A (Dectin-1) signals through the classic calcineurin/NF...
CLEC7A (Dectin-1) was identified as a primary receptor for b...
CLM7/TREM5 is a member of the CMRF-35/immune receptor expres...
CLOCK is a central element of the core clock mechanism that ...
Clock is a central element of the core clock mechanism that ...
Cloning and analysis of full length chicken MyD88 revealed a...
Close homolog of L1 (CHL1) is a member of the L1 family of c...
Close homolog of L1 (CHL1), associates with Contactin-6/NB-3...
Closing (inhibition) of the L-type calcium channels in the p...
Clostridial neurotoxins, when taken up by human neurons, blo...
Clustering of Integrin alphaIIb beta3 complexes results in t...
CNTN1 (F3, contactin-1) is a neuronal cell adhesion protein ...
Co-activation of P2Y1 and P2Y12 is necessary for complete pl...
Co-immunoprecipitation of rat Prlr and Stat5 in mutated Prlr...
Co-immunoprecipitation of rat Stat5 and Prlrs mutated to hav...
Co-transcriptional pre-mRNA splicing is not obligatory. Pre-...
Co-transcriptional pre-mRNA splicing is not obligatory. Pre-...
Co-transfection of recombinant mouse Smad7 and recombinant h...
Coactivator-associated arginine methyltransferase 1 (CARM1, ...
Coactivator-associated arginine methyltransferase 1 (CARM1, ...
Cobalamin (Cbl, vitamin B12) is a nutrient essential for nor...
Coenzyme A (CoA) is a ubiquitous cofactor that functions as ...
Coexpression of mouse Shh and human ADAM17 in Bosc23 cells r...
Coexpression of tagged recombinant human SMURF2 and mouse Sm...
Cohesin complexes dissociate from chromosomal arms in promet...
Cohesin, in complex with WAPAL and PDS5 (PDS5A or PDS5B) bin...
COL25A1 is a brain-specific membrane-bound collagen. Proteol...
COLEC11 (CL-K1) binds D-mannose, L-fucose, N-acetylglucosami...
COLEC12 (CL-P1, SCARA4, SRCL, NSR2) bound to yeast or bacter...
COLEC12 (SCARA4) binds beta-glucan (Jang et al. 2009), N-ace...
Collagen alpha-1(XXIV) is a fibrillar-like collagen chain th...
Collagen contains (2S,3S)-3-hydroxyproline (3-Hyp), though m...
Collagen fibril diameter and spatial organisation are depend...
Collagen fibrils are the principal tensile element of the ex...
Collagen is a family of at least 29 structural proteins deri...
Collagen IX, expressed in cartilage and eye, is a high-avidi...
Collagen precursors are co-translated into the ER, where pos...
Collagen trimers in triple-helical form, referred to as proc...
Collagen type IXI is a member of the fibril-associated colla...
Collagen type VI forms dimers and tetramers before secretion...
Collagen type VIII (COL8) is a major component of Descemet’s...
Collagen type VIII is a short chain, network-forming collage...
Collagen type VIII is a short chain, network-forming collage...
Collagen type VIII is a short chain, network-forming collage...
Collagen type XI has 3 alpha chain types. The alpha1(XI) and...
Collagen type XI has 3 types of alpha chain. The alpha1(XI) ...
Collagen type XII is a member of the fibril-associated colla...
Collagen type XIV is a member of the fibril-associated colla...
Collagen type XIV is a member of the fibril-associated colla...
Collagen type XIX is a FACIT (fibril-associated collagens wi...
Collagen type XVI is a member of the FACIT (fibril-associate...
Collagen type XVII (BP180) forms a family with collagen type...
Collagen type XVII, identified as the 180-kDa bullous pemphi...
Collagen type XVIII is a heparan sulfate proteoglycan associ...
Collagen type XX is a member of the FACIT (fibril-associated...
Collagen type XXI is a member of the FACIT (fibril-associate...
Collagen type XXII is a member of the FACIT (fibril-associat...
Collagen type XXIII binds alpha2beta1 integrin.
Collagen type XXIII is a type II transmembrane collagen with...
Collagen type XXIII is a type II transmembrane collagen with...
Collagen type XXIII, a transmembrane collagen, binds integri...
Collagen VI dimers combine to form tetramers before secretio...
Collagen VII forms anchoring fibrils, composed of antiparall...
Collagen VII forms anchoring fibrils, composed of antiparall...
Collagen VII triple-helices form an anti-parallel dimer, ass...
Collagen was for many years considered the only source of 4-...
Collagen X forms extended hexagonal networks (Kwan et al. 19...
Collagen X forms extended hexagonal networks (Kwan et al. 19...
Collagen X is believed to form extended hexagonal networks (...
Collagen X is thought to form extended hexagonal networks (K...
Collagen X is thought to form extended hexagonal networks (K...
Collagen XI consists of alpha-1, alpha-2, and alpha-3 chains...
Collagen XVI is a homotrimeric member of the fibril-associat...
Collagen XVII is a transmembrane protein. It is a structural...
Collagens IV, VI, VIII and X form open networks. Type IV net...
Collagens type XV and XVIII are closely related non-fibrilla...
Collagens XV and XVIII are basement membrane associated coll...
Colonic epithelial cells use integrin alpha2beta1 to adhere ...
Combination of chromatin immunoprecipitation (ChIP) microarr...
Commissural axons project to the floor plate, attracted by t...
Communication at the synapse involves the release of glutama...
Comparison of ALAS1 protein translated in vitro with that re...
Comparison of ALAS2 protein translated in vitro with that re...
Complement activation is due to a cascade of proteolytic ste...
Complement activity is non-specific and requires the assembl...
Complement C7 binds C5b:C6 to form the C5b:C6:C7 hydrophobic...
Complement C9 is the final component incorporated into the m...
Complement factor I (CFI) is a complex of one heavy and one ...
Complement factor I (CFI) is a serine protease that inhibits...
Complement factor I (CFI) is a serine protease that inhibits...
Complement factor I binds the factor H:C3b complex.
Complement factor I binds to the Factor H:C3b complex.
Complement factor I cleaves the alpha chain of C3b at two po...
Complement protein C1q binds either to antibody-antigen comp...
Complement proteins C8 and C9 can bind to VTN:C5b:C6:C7 to f...
Complement Receptor 1 (CR1) displaces the activated enzyme c...
Complement Receptor 1 (CR1) is a widely distributed cell su...
Complex formation between p75NTR and RHOA can leads to inhib...
Complex formed by RBL1 (p107), E2F4/5, DP1/2 and a trimer of...
Complex I (NADH:ubiquinone oxidoreductase or NADH dehydrogen...
Complex IV (COX, cytochrome c oxidase) contains the hemeprot...
Complexes containing small RNAs and AGO1 or AGO2 are observe...
Components of N type VGCC. The properties of the voltage gat...
Components of P/Q type VGCC. The properties of the voltage g...
Components of R type VGCC. The properties of the voltage gat...
Components of the evolutionarily conserved complex of HIRA, ...
Composed of Acetylated SL1, phosphorylated UBF-1 bound the r...
Concomitant with the completion of reverse transcription, th...
Condensation of chromosomes in prophase is mediated by chrom...
Condensation with cleavage of one phosphate group of shikima...
Conformational changes in the C1 complex result in activatio...
Congenital disorders of glycosylation (CDG, previously calle...
Congenital disorders of glycosylation (CDGs) are a group of ...
Connexin-interacting proteins appear to function in regulati...
Connexins (Cxs) are encoded by a large gene family predicted...
Connexins follow the classical secretory transport route fro...
Connexon-containing transport vesicles have been shown to em...
Connexons may also traffic using a microtubule-independent m...
Constituents of the platelet alpha granule membrane are inco...
Constituents of the platelet dense granule membrane are inco...
Constitutive phosphorylation at Ser303 within the regulatory...
Constitutive phosphorylation at Ser307 was shown to inhibit ...
Constitutive phosphorylation of SHC1 was directly demonstrat...
Constitutively active PI3K complex produces PIP3 in the abse...
Constitutively recycling GluR2 containing AMPA receptors in ...
Constructs containing the C-terminal SH3-SH2-SH3 domain of V...
Contact between dendritic cells (DC) and resting T cells is ...
Contactin-1 (CNTN1) is composed of six Ig domains followed b...
Contains 1 RING-type zinc finger and hence works as an E3-ub...
COP1 is one of several E3 ubiquitin ligases responsible for...
COPII components (known as Sec13p, Sec23p, Sec24p, Sec31p, a...
Copine 1, 3, 6 and 7 (CPNE1,3,6,7) are a family of calcium-d...
Copper (Cu2+) is essential for many important biological pro...
Copper chaperone of superoxide dismutase (CCS) transfers a c...
Copper chaperone of superoxide dismutase (CCS) transfers a c...
Copper-containing superoxide dismutase is localized in the p...
Coproporpyrinogen III (COPRO3) enters the mitochondrial inte...
Coproporpyrinogen III enters the mitochondrial intermembrane...
Correctly folded proteins, after being released from the Cal...
Corticosterone, NADPH + H+, and O2 react to form 18-hydroxyc...
Corticotropin (Adrenocorticotropic hormone, ACTH) acts throu...
Corticotropin (Adrenocorticotropic hormone, ACTH) acts throu...
Corticotropin (adrenocorticotropic hormone, ACTH) is a 39-am...
Corticotropin-releasing hormone (CRH), originally named cort...
Cortisol and NADP+ react to form cortisone, NADPH, and H+. T...
Cortisol is translocated from the mitochondrial matrix into ...
Cortisol, the major human glucocorticoid, is synthesized in ...
Cot functions upstream of NIK in the CD28-costimulation sign...
Cot/Tpl 2 is a serine/threonine kinase of the mitogen activa...
Covalent (irreversible) TKIs, pelitinib, WZ4002, HKI-272, ca...
Covalent (irreversible) tyrosine kinase inhibitors (TKIs), p...
CpG DNA is an unusual Pathogen-Associated Molecular Pattern ...
CPOX (coproporphyrinogen III oxidase) localized in the mitoc...
CPT2, associated with the inner mitochondrial membrane, cata...
CR1 and MCP are widely distributed cell surface molecules th...
Creatine kinase octamers associated with the inner mitochond...
CREB is phosphorylated at serine 133 by any of the four isof...
CREB is phosphorylated at Serine 133 by RSK1/2/3.
CREB readily dimerizes.
CREBBP (CBP) is named after its interaction with the CRE-bin...
CREBBP (CBP) is named after its interaction with the CRE-bin...
CREG has the ability to protect host cells from chicken comp...
CREM, a complement regulatory protein in chicken, consists o...
CRK (CT10 Regulator of Kinase) is composed of one SH2 and on...
Crk family of adaptor molecules consists of CrkI with one SH...
Crk is an adaptor protein with one SH2 and two SH3 domains. ...
CRM1 associates directly with Rev through the Rev nuclear e...
Crm1 is a nucleocytoplasmic transport factor that is believe...
CRMP-3 does not have the conserved serine 522 and based on s...
CRMPs are a small family of plexinA-interacting cytosolic ph...
cRNA bound by NP and trimeric polymerase, capable of vRNA sy...
Cross-linking experiments performed in the yeast system have...
Cross-linking of FCGRs with IgG coated immune complexes resu...
Crosslinking of receptors associated with DAP12 leads to pho...
Cry (Cry1 and Cry2) and Per (Per1, Per2) proteins form compl...
CRY (CRY1 and CRY2) and PER (PER1, PER2, PER3) proteins form...
Cry proteins facilitate the entry of Per proteins into the n...
CRY1 and CRY2 bind the unphosphorylated BMAL1:CLOCK (ARNTL:C...
Cry1 and Cry2 bind unphosphorylated Bmal1:Clock/Npas2 (Arntl...
CRYPTOCHROME, PERIOD, and a kinase (CKIepsilon or CKIdelta) ...
Cryptochrome, Period, and kinase (CKIepsilon or CKIdelta) fo...
Crystallographic evidence indicates that the IRE1 homodimer ...
CSK bound to integrin alphaIIb beta3 negatively regulates SR...
Csk is a tyrosine kinase that phosphorylates the negative re...
Csnk1a1 binds the Smo C-terminal tail after Shh stimulation ...
CSNK1E and DVL physically interact in vivo and CSNK1E phosph...
CTDNEP1:CNEP1R1 serine/threonine protein phosphatase complex...
CTLA4 associates with the SH2 domain containing tyrosine pho...
CTLA4 binds with high affinity to the ligands B71 and B72. T...
CTLA4 is one of the best studied inhibitory receptors of the...
CTNNBIP1 (also known as ICAT) is an 81 amino-acid protein th...
Cu-Zn superoxide dismutase (SOD1), originally known as eryth...
Cubilin (CUBN) is a membrane-associated protein colocalizing...
CUL3:KLHL12:RBX1 polyubiquitinates Dishevelled, targeting it...
Cultured mouse endothelial cells expressing Notch1 are activ...
Cultured mouse endothelial cells expressing Notch1 are activ...
Current literature suggests that 5S-hydroxy-eicosatetraenoic...
Cx proteins are cotranslationally inserted into ER membranes...
Cx26 has also been reported to insert post-translationally i...
CX3CL1 (fractalkine) is a member of the chemokine superfamil...
CXC-Chemokine receptor 5 (CXCR5) was originally called Burki...
CXCL12 (stromal cell-derived factor-1, SDF-1) (Shirozu M et ...
CXCR1 (high affinity interleukin-8 receptor A) (Holmes WE et...
CXCR2 (High affinity interleukin-8 receptor B) (Murphy PM an...
CXCR3 (Loetscher M et al, 1996) is predominantly expressed o...
CXCR6 (formerly called STRL33, BONZO, and TYMSTR) was assign...
CXXC4 binds to DVL to negatively regulate WNT-dependent gene...
Cxxc4 was identified as Idax in a two-hybrid screen of a rat...
Cyclic adenosine 3',5'-monophosphate (cAMP) induces gene tra...
Cyclic di-GMP (c-di-GMP) and cyclic-di-AMP (c-di-AMP) are ub...
Cyclic dinucleotides (such as c-di-GMP and c-di-AMP) are sig...
Cyclic GMP phosphodiesterase are hydrolases selective for cA...
Cyclic GMP-AMP (cGAMP) synthase (cGAS) was identified as a c...
Cyclic guanosine monophosphate (cGMP) is an important second...
Cyclic nucleotide phosphodiesterases (PDEs) are a large fami...
Cyclic-AMP-dependent transcription factor 1 (ATF1) can be ph...
Cyclic-GMP-dependent phosphodiesterase 6 (Pde6) is a membran...
Cyclin A can also form complexes with Cdc2 (Cdk1). Together ...
Cyclin A is believed to be recognized by the APC/C:Cdc20 com...
Cyclin A is synthesized and associates with Cdc2 in G1. Cycl...
Cyclin A, functions in mitosis as well as DNA replication a...
Cyclin A-Cdk2 (CCNA:CDK2) prevents unscheduled APC reactivat...
Cyclin A-Cdk2 prevents unscheduled APC reactivation during S...
Cyclin A:Cdc2 complexes are detected in the nucleus earlier ...
Cyclin A:Cdc2 complexes translocate to the nucleus in G1 and...
Cyclin A:Cdk2 plays a key role in S phase entry by phosphory...
Cyclin B is believed to be recognized by the APC/C:Cdc20 com...
Cyclin D is targeted for degradation by multi-ubiquitination...
Cyclin D turnover is regulated by ubiquitination and protea...
Cyclin D:Cdk4 mediated phosphorylation of RB1 releases RB1 f...
Cyclin D:CDK4/6 complexes translocate to the nucleus from th...
Cyclin dependent kinases are themselves catalytically inacti...
Cyclin E - Cdk2 complexes control the transition from G1 int...
Cyclin E forms a complex with cdk2 and collaborates with the...
Cyclin-dependent kinase 5 (CDK5), a member of the serine/thr...
Cyclization and dephosphorylation of DAHP, catalyzed by AroB...
Cyclopentenone prostaglandins comprise a family of molecules...
Cyclophilin A (CyPA)1 is an intracellular protein belonging ...
Cyclophosphamide (CPA) is an alkylating agent used in cancer...
CYLD is an ovarian tumor (OTU) domain-containing deubiquitin...
CYP1A2 oxidizes a variety of structurally unrelated compound...
CYP27A1, a mitochondrial matrix sterol hydroxylase, catalyse...
CYP27A1, a mitochondrial matrix sterol hydroxylase, catalyse...
CYP27A1, a mitochondrial matrix sterol hydroxylase, catalyse...
CYP2A13 can also 7-hydroxylate coumarin. It shares a 93.5% i...
CYP2D6 (debrisoquine 4-hydroxylase) has a wide substrate spe...
CYP2E1 can catalyze the oxidation of the vinyl halide vinyl ...
CYP2E1 can metabolize and activate a large number of solvent...
CYP2S1 is a recently discovered cytochrome P450 enzyme on th...
CYP2W1 is a so-called "ophan P450", a cytochrome P450 enzyme...
CYP3A43 belongs to the cytochrome P450 3A family, of which C...
CYP3A7 is only expressed in fetal liver and not in adults. I...
Cystathionine is cleaved to cysteine, oxobutanoate, and ammo...
Cysteine sulfinic acid decarboxylase (Csad) mediates the dec...
Cysteine sulfinic acid decarboxylase (CSAD) mediates the dec...
Cystine bonds are formed in Proinsulin-1 between cysteine re...
Cystinosin (CTNS) is an integral lysosomal membrane protein ...
Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase1 (...
Cytochrome b reductase 1 not only reduces ferrous iron in th...
Cytochrome b5 reductase (CYB5R3) catalyzes the reduction of ...
Cytochrome c released to the cytosol from the mitochonridal ...
Cytochrome P450 11B1, mitochondrial (CYP11B1) possesses ster...
Cytochrome P450 11B1, mitochondrial (CYP11B1) usually hydrox...
Cytochrome P450 11B1, mitochondrial (CYP11B1) usually hydrox...
Cytochrome P450 11B2, mitochondrial (CYP11B2 aka aldosterone...
Cytochrome P450 11B2, mitochondrial (CYP11B2 aka aldosterone...
Cytochrome P450 11B2, mitochondrial (CYP11B2 aka aldosterone...
Cytochrome P450 1B1 (CYP1B1) can oxidise a variety of struct...
Cytochrome P450 1B1 (CYP1B1) can oxidise a variety of struct...
Cytochrome P450 1B1 (CYP1B1) can oxidise a variety of struct...
Cytochrome P450 2A13 is able to oxidise aflatoxin M1 (AFM1) ...
Cytochrome P450 2U1 (CYP2U1) catalyses the hydroxylation of ...
Cytochrome P450 2U1 (CYP2U1) catalyses the hydroxylation of ...
Cytochrome P450 4F22 (CYP4F22) is thought to 20-hydroxylate ...
Cytochrome P450 4F22 (CYP4F22) is thought to 20-hydroxylate ...
Cytochrome P450 4F22 (CYP4F22) is thought to 20-hydroxylate ...
Cytochrome P450 8B1 (CYP8B1, sterol 12-alpha- hydroxylase) h...
Cytochrome P450s 1A1 (CYP1A1), 1A2 (CYP1A2), and 1B1 (CYP1B1...
Cytokines are small proteins that regulate and mediate immun...
Cytokinesis requires the central spindle, which forms during...
Cytoplasmic cytochrome c binds to apoptotic protease activat...
Cytoplasmic target proteins containing the SH2 domain can bi...
Cytoplasmic target proteins containing the SH2 domain can bi...
Cytoplasmic tyrosine kinases such as CHK1 (Csk homologous ki...
Cytosine residues in the main promoter of silenced rRNA gene...
Cytosolic (R)-3-aminoisobutyric acid is known to be able to ...
Cytosolic 2-amino 3-carboxymuconate semialdehyde reacts non-...
Cytosolic 3-hydroxyanthranilate oxygenase catalyzes the reac...
Cytosolic 3-ureidopropionase catalyzes the reaction of 3-ure...
Cytosolic 4-(2-aminophenyl)-2,4-dioxobutanoate is thought to...
Cytosolic 4-hydroxyphenylpyruvate dioxygenase (HPD) catalyze...
Cytosolic 4-trimethylaminobutyraldehyde dehydrogenase tetram...
Cytosolic 5'-nucleotidase 3 (NT5C3) catalyzes the hydrolysis...
Cytosolic 5'-nucleotidase IA (NT5C1A) catalyzes the hydrolys...
Cytosolic 5'-nucleotidase IA catalyzes the hydrolysis of pur...
Cytosolic 5'3'-nucleotidase (NT5C) catalyzes the hydrolysis ...
Cytosolic 5'3'-nucleotidase (NT5C) catalyzes the hydrolysis ...
Cytosolic 6-phosphogluconolactonase (PGLS) catalyzes the hyd...
Cytosolic AASDHPPT (alpha-aminoadipic semialdehyde dehydroge...
Cytosolic acetaldehyde crosses the mitochondrial inner membr...
Cytosolic acetyl-CoA carboxylase 1 (ACACA) catalyzes the rea...
Cytosolic acetyl-CoA carboxylases 1 and 2 (Btn-ACACA/B:2Mn2+...
Cytosolic ACSS2 (acetyl-coenzyme A synthetase) catalyzes the...
Cytosolic ADAL (Adenosine DeAminase-Like) catalyzes the reac...
Cytosolic ADAL (Adenosine DeAminase-Like) catalyzes the reac...
Cytosolic adenosine deaminase (ADA) catalyzes the hydrolysis...
Cytosolic adenosine linase (ADK) catalyzes the reactions of ...
Cytosolic adenosine phosphotransferase catalyzes the reactio...
Cytosolic adenylate kinase 1 (AK1) catalyzes the reversible ...
Cytosolic adenylate kinase 1 (AK1) catalyzes the reversible ...
Cytosolic adenylate kinase 5 [AK5] catalyzes the reactions o...
Cytosolic adenylate kinase 5 [AK5] catalyzes the reactions o...
Cytosolic ADH alpha dimer catalyzes the reaction of abacavir...
Cytosolic ADSL catalyzes the cleavage of adenylosuccinate to...
Cytosolic ADSS catalyzes the reaction of inosine 5'-monophos...
Cytosolic ADSS dimer catalyzes the reaction of inosine 5'-mo...
Cytosolic AKR1B1 (aldose reductase) catalyzes the reaction o...
Cytosolic ALAD (delta-aminolevulinate dehydratase) catalyzes...
Cytosolic alcohol dehydrogenase catalyzes the reaction of et...
Cytosolic aldolase B (ALDOB) catalyzes the reaction of D-fru...
Cytosolic aldolase catalyzes the cleavage of D-fructose 1,6-...
Cytosolic aldolase catalyzes the reversible reaction of dihy...
Cytosolic aldolase catalyzes the reversible reaction of fruc...
Cytosolic aminocyclases 1 and 3 (ACY1,3) can hydrolyse N-acy...
Cytosolic aminocyclases 1 and 3 (ACY1,3) can hydrolyse N-acy...
Cytosolic AMP deaminase (AMPD) catalyzes the hydrolysis of A...
Cytosolic AMP, GMP, and IMP stimulate the association of pho...
Cytosolic APRT dimer catalyzes the reaction of adenine and 5...
Cytosolic Arginase 1 (ARG1) trimer catalyzes the hydrolysis ...
Cytosolic argininosuccinate lyase (ASL) catalyzes the revers...
Cytosolic argininosuccinate lyase (ASL) catalyzes the revers...
Cytosolic argininosuccinate synthase catalyzes the reaction ...
Cytosolic argininosuccinate synthetase (ASS1) catalyzes the ...
Cytosolic arylformamidase (AFMID) catalyzes the hydrolysis o...
Cytosolic asparagine synthase (ASNS) catalyzes the reaction ...
Cytosolic aspartate aminotransferase (glutamate oxaloacetate...
Cytosolic aspartate aminotransferase (glutamate oxaloacetate...
Cytosolic ATP reversibly associates with GLUT1. This associa...
Cytosolic beta-alanine is known to be able to enter the mito...
Cytosolic bile acid-CoA conjugates (choloyl-CoA; chenodeoxyc...
Cytosolic branched-chain-amino-acid aminotransferase (BCAT1)...
Cytosolic branched-chain-amino-acid aminotransferase (BCAT1)...
Cytosolic caspase 3 cleaves p-STK3 (p-MST2) to yield an acti...
Cytosolic caspase 3 cleaves p-STK4 (p-MST1) to yield an acti...
Cytosolic creatine kinase catalyzes the reaction of creatine...
Cytosolic CSNK1G2 (casein kinase 1, gamma 2) catalyzes the p...
Cytosolic CTP synthase 1 (CTPS) catalyzes the reaction of UT...
Cytosolic CTP synthase 2 (CTPS) catalyzes the reaction of UT...
Cytosolic cytidine deaminase catalyzes the hydrolysis of cyt...
Cytosolic debranching enzyme associated with glycogen granul...
Cytosolic deoxycytidine kinase (DCK) catalyzes the reactions...
Cytosolic deoxycytidine kinase (DCK) catalyzes the reactions...
Cytosolic deoxycytidylate deaminase (DCTD) catalyzes the hyd...
Cytosolic deoxyhypusine hydroxylase catalyzes the irreversib...
Cytosolic deoxyhypusine synthase catalyzes the reaction of E...
Cytosolic deoxythymidylate kinase (DTYMK) catalyzes the reve...
Cytosolic deoxythymidylate kinase (DTYMK) catalyzes the reve...
Cytosolic dihydrofolate reductase catalyzes the reaction of ...
Cytosolic dihydrofolate reductase catalyzes the reaction of ...
Cytosolic dihydropteridine reductase (QDPR) catalyzes the re...
Cytosolic dihydropyrimidinase tetramer catalyzes the reactio...
Cytosolic dihydropyrimidinase tetramer catalyzes the reactio...
Cytosolic dihydropyrimidine dehydrogenase catalyzes the reac...
Cytosolic dihydropyrimidine dehydrogenase catalyzes the reac...
Cytosolic dihydroxyacetone kinase (DAK) catalyzes the reacti...
Cytosolic diphthamide biosynthesis protein 5 (DPH5) transfer...
Cytosolic diphthamide biosynthesis protein 6 (DPH6) ligates ...
Cytosolic eIF5A undergoes a unique two-step post-translation...
Cytosolic enolase catalyzes the reversible magnesium-depende...
Cytosolic enolase catalyzes the reversible magnesium-depende...
Cytosolic enolase catalyzes the reversible reaction of 2 pho...
Cytosolic enolase dimer catalyzes the reversible reaction of...
Cytosolic ERBB4s80 is able to translocate to mitochondria wh...
Cytosolic fatty acid synthase (FAS) complex catalyzes the re...
Cytosolic Fe/S protein biogenesis depends on the electron tr...
Cytosolic Fe/S protein biogenesis depends on the electron tr...
Cytosolic folylpolyglutamate synthase catalyzes the reaction...
Cytosolic folylpolyglutamate synthase catalyzes the reaction...
Cytosolic formimidoyltransferase-cyclodeaminase (FTCD) catal...
Cytosolic fructose-1,6-bisphosphatase catalyzes the physiolo...
Cytosolic fumarylacetoacetase catalyzes the hydrolysis of 4-...
Cytosolic galactokinase (GALK1) catalyses the reaction of AT...
Cytosolic galactose-1-phosphate uridylyltransferase (GALT) c...
Cytosolic gamma-butyrobetaine hydroxylase dimer (BBOX1) cata...
Cytosolic GAPDH catalyzes the reversible reaction of 1,3-bis...
Cytosolic GAPDH catalyzes the reversible reaction of glycera...
Cytosolic GDP-mannose reacts with dolichyl phosphate in the ...
Cytosolic glucokinase and the three isoforms of hexokinase c...
Cytosolic glucose 6-phosphate is transported to the endoplas...
Cytosolic glucose-6-phosphate dehydrogenase (G6PD) catalyzes...
Cytosolic glutamic-pyruvate transaminase (alanine aminotrans...
Cytosolic glutamic-pyruvate transaminase (alanine aminotrans...
Cytosolic glutamine synthetase (glutamate-ammonia ligase - G...
Cytosolic glutaredoxin (oxidized) and glutathione (reduced) ...
Cytosolic glutathione peroxidase (GPX1) tetramer catalyzes t...
Cytosolic glutathione reductase catalyzes the reaction of gl...
Cytosolic glyceraldehyde 3-phosphate dehydrogenase catalyzes...
Cytosolic glycogen branching enzyme (GBE1) associated with g...
Cytosolic glycogen branching enzyme (GBE1) associated with g...
Cytosolic glycogen branching enzyme (GBE1) associated with g...
Cytosolic glycogen breakdown occurs via the same chemical st...
Cytosolic GMP reductase (GMPR) catalyzes the reaction of GMP...
Cytosolic GMP synthase (GMPS) catalyzes the reaction of xant...
Cytosolic GMPS (guanine monophosphate synthetase) catalyzes ...
Cytosolic GNPNAT1 catalyzes the reaction of glucosamine 6-ph...
Cytosolic GOT1 catalyzes the reversible transamination of as...
Cytosolic GOT1 catalyzes the reversible transamination of ox...
Cytosolic guanidinoacetate methyltransferase catalyzes the r...
Cytosolic guanine deaminase (GDA) catalyzes the reaction of ...
Cytosolic guanylate kinase 1 (GUK1) catalyzes the reversible...
Cytosolic guanylate kinase 1 (GUK1) catalyzes the reversible...
Cytosolic GUK1 (guanylate kinase 1) catalyzes the reaction o...
Cytosolic GUK1 (guanylate kinase 1) catalyzes the reaction o...
Cytosolic histidine ammonia lyase (HAL) catalyzes the reacti...
Cytosolic HMBS (hydroxymethylbilane synthase) catalyzes the ...
Cytosolic homogentisate 1,2-dioxygenase (HGD) catalyzes the ...
Cytosolic hydroxymethylbilane reacts spontaneously to form u...
Cytosolic hypoxanthine-guanine phosphoribosyltransferase (HP...
Cytosolic IDH1 (isocitrate dehydrogenase 1) homodimer cataly...
Cytosolic imidazolonepropionase catalyzes the hydrolysis of ...
Cytosolic IMPDH2 (inosine-5'-monophosphate dehydrogenase 2) ...
Cytosolic indoleamine 2,3-dioxygenase (IDO) catalyzes the co...
Cytosolic indoleamine 2,3-dioxygenase 2 (IDO2) catalyzes the...
Cytosolic isopentenyl diphosphate isomerase (IPP isomerase) ...
Cytosolic ITPA dimer catalyzes the reaction of dITP and wate...
Cytosolic ITPA dimer catalyzes the reaction of ITP and water...
Cytosolic ITPA dimer catalyzes the reaction of XTP and water...
Cytosolic ketohexokinase (KHK) catalyzes the reaction of D-f...
Cytosolic KIBRA (WWC1) binds LATS proteins. The stoichiometr...
Cytosolic kynureninase catalyzes the hydrolysis of 3-hydroxy...
Cytosolic kynurenine 3-monooxygenase catalyzes the reaction ...
Cytosolic kynurenine formamidase catalyzes the hydrolysis of...
Cytosolic lactate dehydrogenase catalyzes the freely reversi...
Cytosolic lactate dehydrogenase catalyzes the reversible rea...
Cytosolic lactate dehydrogenase catalyzes the reversible rea...
Cytosolic lactate dehydrogenase catalyzes the reversible rea...
Cytosolic LATS1 and LATS2 are phosphorylated by phospho-STK3...
Cytosolic LATS1 and LATS2 are phosphorylated by phospho-STK3...
Cytosolic LATS1 and LATS2 are phosphorylated by phospho-STK4...
Cytosolic LATS1 and LATS2 are phosphorylated by phospho-STK4...
Cytosolic levels of abacavir are determined by the balance o...
Cytosolic malate dehydrogenase catalyzes the reaction of mal...
Cytosolic malate dehydrogenase catalyzes the reaction of mal...
Cytosolic maleylacetoacetic acid isomerase (GSTZ1) catalyzes...
Cytosolic MOB1A and MOB1B are phosphorylated by phospho-STK3...
Cytosolic MOB1A and MOB1B are phosphorylated by phospho-STK3...
Cytosolic MOB1A and MOB1B are phosphorylated by phospho-STK4...
Cytosolic MOB1A and MOB1B are phosphorylated by phospho-STK4...
Cytosolic MTHFR dimer catalyzes the reaction of 5,10-methyle...
Cytosolic N-myristoyl Gag polyprotein is conjugated with a s...
Cytosolic N-myristoyl Gag polyprotein is conjugated with a s...
Cytosolic NICD1 PEST domain mutants are expected to transloc...
Cytosolic NICD1 translocates to the nucleus.
Cytosolic nicotinate phosphoribosyltransferase (NaPRT) catal...
Cytosolic NP (purine nucleoside phosphorylase) catalyzes the...
Cytosolic NPHP4 protein binds LATS proteins to form a comple...
Cytosolic NT5C2 (5'-nucleotidase, cytosolic II) catalyzes th...
Cytosolic nucleoside diphosphate kinases catalyze the revers...
Cytosolic nucleoside diphosphate kinases catalyze the revers...
Cytosolic nucleoside phosphorylase (NP) trimer catalyzes the...
Cytosolic nucleoside phosphorylase (NP) trimer catalyzes the...
Cytosolic nucleoside phosphorylase (NP) trimer catalyzes the...
Cytosolic nucleoside phosphorylase (NP) trimer catalyzes the...
Cytosolic NUDT5 dimer (ADP-ribose pyrophosphatase) catalyzes...
Cytosolic omega class glutathione transferases (GSTO1 and GS...
Cytosolic pantothenate kinases catalyze the reaction of ATP ...
Cytosolic PCK1 (phosphoenolpyruvate carboxykinase 1) catalyz...
Cytosolic PCK1 (phosphoenolpyruvate carboxykinase 1) catalyz...
Cytosolic PFAS (phosphoribosylformylglycinamidine synthase) ...
Cytosolic PGAM (phosphoglycerate mutase) catalyzes the rever...
Cytosolic PGAM (phosphoglycerate mutase) catalyzes the rever...
Cytosolic PGK (phosphoglycerate kinase) catalyzes the revers...
Cytosolic PGK (phosphoglycerate kinase) catalyzes the revers...
Cytosolic PGM3 catalyzes the isomerization of N-acetyl-D-glu...
Cytosolic phophoribosyl pyrophosphate synthetase catalyzes t...
Cytosolic phospho-LATS1, complexed with MOB1, catalyzes the ...
Cytosolic phospho-LATS1, complexed with MOB1, catalyzes the ...
Cytosolic phospho-LATS2, complexed with MOB1, catalyzes the ...
Cytosolic phospho-LATS2, complexed with MOB1, catalyzes the ...
Cytosolic phosphocreatine spontaneously hydrolyzes to yield ...
Cytosolic phosphofructokinase 1 (PFK1) catalyzes the irrever...
Cytosolic phosphofructokinase 1 catalyzes the reaction of fr...
Cytosolic phosphofructokinase 2 (PFK2) catalyzes the irrever...
Cytosolic phosphoglucomutase (PGM) catalyses the reversible ...
Cytosolic phosphoglucomutase (PGM) catalyzes the reversible ...
Cytosolic phosphogluconate dehydrogenase (PGD) catalyzes the...
Cytosolic phosphoglucose isomerase catalyzes the reversible ...
Cytosolic phosphoglycerate kinase catalyzes the reaction of ...
Cytosolic phosphoglycerate kinase complexed with magnesium c...
Cytosolic phosphoglycerate mutase catalyzes the reversible i...
Cytosolic phosphoglycerate mutase dimer catalyzes the revers...
Cytosolic phosphoribosyl pyrophosphate synthetase 1 catalyze...
Cytosolic porphobilinogen deaminase catalyzes the polymeriza...
Cytosolic PPA1 (pyrophosphatase (inorganic) 1) catalyzes the...
Cytosolic PPAT (phosphoribosyl pyrophosphate amidotransferas...
Cytosolic PPAT (phosphoribosyl pyrophosphate amidotransferas...
Cytosolic PRKD1 (protein kinase D1) catalyzes the phosphoryl...
Cytosolic proteins are also recruited to the cyctoplasmic fa...
Cytosolic pterin-4-alpha-carbinolamine dehydratase (PCDB1) c...
Cytosolic purine 5'-nucleotidase (NT5C2) catalyzes the hydro...
Cytosolic pyruvate kinase (PKM2) catalyzes the irreversible ...
Cytosolic pyruvate kinase catalyzes the transfer of a high-e...
Cytosolic rat HSL is phosphorylated on serine residues 659 a...
Cytosolic ribonucleotide reductase catalyzes the reduction o...
Cytosolic ribonucleotide reductase catalyzes the reduction o...
Cytosolic ribulose-5-phosphate-3-epimerase (RPE) catalyzes t...
Cytosolic ribulose-5-phosphate-3-epimerase (RPE) catalyzes t...
Cytosolic Sec13p-Sec31p complexes bind to pre-bound Sec23p-S...
Cytosolic serine hydroxymethyltransferase catalyzes the reve...
Cytosolic serine hydroxymethyltransferase catalyzes the reve...
Cytosolic serine hydroxymethyltransferase tetramer (SHMT1) c...
Cytosolic SORD (sorbitol dehydrogenase) catalyzes the reacti...
Cytosolic thiamin pyrophosphokinase (TPK1) catalyzes the rea...
Cytosolic thioredoxin reductase catalyzes the reaction of th...
Cytosolic thymidine kinase 1 (TK1) catalyzes the reaction of...
Cytosolic thymidine phosphorylase (TYMP) catalyzes the rever...
Cytosolic thymidine phosphorylase (TYMP) catalyzes the rever...
Cytosolic thymidylate synthase catalyzes the reaction of dUM...
Cytosolic TPI1 (triosephosphate isomerase 1) catalyzes the r...
Cytosolic TPI1 (triosephosphate isomerase 1) catalyzes the r...
Cytosolic transketolase catalyzes the reaction of D-erythros...
Cytosolic transketolase catalyzes the reaction of D-glyceral...
Cytosolic transketolase catalyzes the reversible reaction of...
Cytosolic transketolase catalyzes the reversible reaction of...
Cytosolic triose phosphate isomerase catalyzes the freely re...
Cytosolic tRNA synthetases catalyze the reactions of tRNAs e...
Cytosolic tryptophan 2,3-dioxygenase (TDO) tetramer catalyze...
Cytosolic tyrosine aminotransferase (TAT) catalyzes the reve...
Cytosolic tyrosine aminotransferase (TAT) catalyzes the reve...
Cytosolic UAP1 catalyzes the reaction of N-acetyl-D-glucosam...
Cytosolic UDP-galactose 4-epimerase catalyzes the interconve...
Cytosolic UDP-glucose pyrophosphorylase 2 (UGP2) catalyzes t...
Cytosolic UMP-CMP kinase (CMPK1) catalyzes the reversible re...
Cytosolic UMP-CMP kinase (CMPK1) catalyzes the reversible re...
Cytosolic UPB1 (beta-ureidopropionase) catalyzes the reactio...
Cytosolic uridine phosphorylase (isoforms UPP1 and UPP2) cat...
Cytosolic uridine phosphorylase (isoforms UPP1 and UPP2) cat...
Cytosolic uridine-cytidine kinase 1 (UCK1) catalyzes the rea...
Cytosolic uridine-cytidine kinase 2 (UCK2) catalyzes the rea...
Cytosolic urocanate hydratase (UROC1) catalyzes the hydrolys...
Cytosolic UROD (uroporphyrinogen decarboxylase) catalyzes th...
Cytosolic UROD (uroporphyrinogen decarboxylase) catalyzes th...
Cytosolic uroporphyrinogen decarboxylase (UROD) catalyzes th...
Cytosolic uroporphyrinogen decarboxylase (UROD) catalyzes th...
Cytosolic uroporphyrinogen III synthase (URO3S) catalyzes th...
Cytosolic UROS (uroporphyrinogen III synthase) catalyzes the...
Cytosolic xanthine dehydrogenase (XDH) catalyzes the reactio...
Cytosolic xanthine dehydrogenase (XDH) catalyzes the reactio...
Cytosolic xanthine dehydrogenase (XDH) catalyzes the reactio...
Cytosolic xanthine dehydrogenase (XDH) catalyzes the reactio...
Cytosolic ZO-1 (TJP1) binds WWTR1 (TAZ) to form a complex. T...
Cytosolic ZO-2 (TJP2) binds WWTR1 (TAZ) to form a complex. T...
Cytosolic ZO-2 (TJP2) binds YAP1 to form a complex (Oka et a...
Cytosolic, homodimeric tartrate-resistant acid phosphatase t...
Cytosolic, non-phosphorylated PGYB dimers (b form) can rever...
Cytosolic, non-phosphorylated PGYB dimers (b form) complexed...
Cytosolic, non-phosphorylated PGYM dimers (b form) can rever...
Cytosolic, non-phosphorylated PGYM dimers (b form) complexed...
Cytosolic, non-specific peptidase (CNDP2) can hydrolyse cyst...
D-beta-hydroxybutyrate dehydrogenase tetramer (BDH1) in the ...
D-beta-hydroxybutyrate dehydrogenase tetramer (BDH1) in the ...
D2HDGH associated with the mitochondrial inner membrane cata...
DAAM1 (Dishevelled-associated activator of morphogenesis) is...
Dab2 is recruited to Cx43-based GJs possibly through a direc...
DACT1, also known as DAPPER1, was identified in Xenopus as a...
DAG along with intracellular calcium signals cooperatively t...
DAG and calcium activate protein kinase C beta (PKC-beta, Ko...
Damage to single nucleotides in a DNA duplex is common, ofte...
Damaged double strand DNA (dsDNA) cannot be successfully use...
Damaged purines are cleaved from the sugar-phosphate backbon...
Damaged pyrimidines are cleaved by pyrimide-specific glycosy...
DAP12 is expressed as a disulfide-bonded homodimer on NK cel...
DARPP-32 is converted into an inhibitor of protein kinase A ...
DARPP-32 is phosphorylated by cAMP-dependent protein kinase ...
DARPP-32 is phosphorylated by cAMP-dependent protein kinase ...
DARS (cytosolic aspartyl tRNA synthetase) catalyzes the reac...
DARS2 (mitochondrial aspartyl tRNA synthetase) catalyzes the...
DCC and Robo1 heterodimerize via conserved sequence elements...
DCC and UNC5A, are also receptors for Netrin-4. The LNT doma...
DCC exerts its pro-apoptotic effect when netrin ligand is ab...
DCC interacts directly with PITPalpha and this interaction i...
DCC interacts with the SH3/SH2 adaptor NCK1 in commissural n...
DCN consists of a core protein of ?40 kDa attached to a sing...
DDIT4 (REDD1) binds 14-3-3 proteins through a conserved 14-3...
DDIT4 (REDD1) gene has a p53 response element immediately up...
De novo fatty acid synthesis in the lactating mammary gland ...
Deadenylation of mRNA proceeds in two steps. According to cu...
Decarboxylation of L-Histidine happens analogously to other ...
Decay accelerating factor (DAF, CD55) is a widely distribute...
Decay-accelerating-factor (DAF, CD55) is a membrane- bound c...
Decorin (DCN) belongs to the small leucine-rich repeat prote...
Defective transcobalamin II (produced by the TCN2 gene) resu...
Defects in AMN cause recessive hereditary megaloblastic anem...
Defects in arylsulfatase B (ARSB, N-acetylgalactosamine 4-su...
Defects in beta-galactosidase (GLB1, MIM:611458) result in g...
Defects in beta-galactosidase (GLB1; MIM:611458) can result ...
Defects in beta-glucuronidase (GUSB; MIM:611499) cause mucop...
Defects in Brca1 confer susceptibility to breast cancer and ...
Defects in CD320 cause methylmalonic aciduria type TCblR (MM...
Defects in GIF cause hereditary intrinsic factor deficiency ...
Defects in HLCS causes holocarboxylase synthetase deficiency...
Defects in hyaluronidase 1 (HYAL1; MIM:607071) cause mucopol...
Defects in in two enzymes required for intestinal digestion ...
Defects in LMBRD1 cause methylmalonic aciduria and homocysti...
Defects in MMAA cause methylmalonic aciduria type cblA (cblA...
Defects in MMAB cause methylmalonic aciduria type cblB (cblB...
Defects in MMACHC cause methylmalonic aciduria and homocysti...
Defects in MMADHC cause methylmalonic aciduria and homocysti...
Defects in MTR cause methylcobalamin deficiency type G (cblG...
Defects in MTRR cause methylcobalamin deficiency type E (cbl...
Defects in MUT cause methylmalonic aciduria, mut type (MMAM;...
Defects in PAPSS2 cause spondyloepimetaphyseal dysplasia Pak...
Defects in STRA6 cause microphthalmia syndromic type 9 (MCOP...
Defects in the CUBN gene cause recessive hereditary megalobl...
Deficiencies in aldolase B arising from mutations in the ald...
Deficiencies in KHK (ketohexokinase) are associated with ess...
Degradation of beta-catenin is initiated following amino-ter...
Degradation of human GLI1 is abrogated in NIH 3T3 cells afte...
Degradation of mRNA from 5' to 3' occurs in three steps. Fir...
Degradation of NFKB p105 frees Tpl2 from p105 allowing it to...
DEGS1 (sphingolipid delta(4)-desaturase 1 / “degenerative sp...
DEGS1 (sphingolipid delta(4)-desaturase 1 / “degenerative sp...
DEGS2 (sphingolipid C4-hydroxylase 2 / “degenerative spermat...
DEGS2 (sphingolipid C4-hydroxylase 2 / degenerative spermato...
Dehydration in the cyclopentane ring of prostaglandin E2 (PG...
Deletion mutants have demonstrated that STAT dimerization ca...
Deletion mutants have demonstrated that STAT dimerization ca...
Deletions in the AXIN1 gene have been identified in 2 hepato...
Delta, gamma and epsilon subunits are predominantly found in...
Delta-1-pyrroline-5-carboxylate synthetase associated with t...
Delta-12-prostaglandin J2 (delta12-PGJ2) is an isomerisation...
Delta-aminolevulinate is transported from the mitochondrial ...
Delta2-THA-CoA is hydrated to 3-hydroxyacyl-CoA intermediate...
Deltex (DTX) protein family in mammals includes four protein...
Dendritic cell-associated C-type lectin-2 (Dectin-2) family ...
Dendritic cells (DCs) and macrophages recognize and phagocyt...
Dendritic cells (DCs) take up and process exogenous particul...
Dentin matrix phosphoprotein 1 (DMP1) is a non-collagenous, ...
Deoxyribonucleotides needed for DNA repair are synthesized d...
Deoxyuridine triphosphatase (DUT) catalyzes the hydrolysis o...
Depending on the nature of the core protein HS-GAGs are atta...
Dephosphorylated BAD translocates to the outer mitochondrial...
Dephosphorylated NFAT-calcineurin (CaN) complex translocates...
Dephosphorylated NFAT-calcineurin (CaN) complex translocates...
Dephosphorylation of CBP/PAG negatively regulates the recrui...
Dephosphorylation of O-phospho-L-serine to L-serine proceeds...
Dephosphorylation of p107 (RBL1) by PP2A complex containing ...
Dephosphorylation of p130 (RBL2) by PP2A complex containing ...
Depletion of the ATPase VCP results in the stabilization of ...
Depurination of a damaged nucleotide is mediated by a purine...
Depyrimidination of a damaged nucleotide in DNA is mediated ...
Depyrimidination of a damaged nucleotide is mediated by a py...
Dermatan sulfate (DS) consists of N-acetylgalactosamine (Gal...
Dermatan sulfate (DS) is thought to be hydrolysed from its d...
Desmosomes represent one of the anchoring junctions mediatin...
Desmosterol is reduced by NADPH + H+ to form cholesterol and...
Despite high-affinity multimeric interaction between EPHs an...
Despite sharing 44% amino acid identity with GLI3, only a sm...
Despite the lower affinity of ferriheme for albumin than for...
Destruction of ubiquitinated HIF-alpha can occur in both the...
Detailed biochemical analyses of all the WNT ligand-receptor...
Detection of DNA damage caused by ionizing radiation results...
Detection of DNA damage caused by ionizing radiation results...
Detection of DNA double-strand breaks involves sensor protei...
Detection of DNA double-strand breaks involves sensor protei...
Deubiquitinating enzyme A (DUBA), an ovarian tumor (OTU) dom...
Deubiquitinating enzyme USP1, bound to its accessory protein...
DFF associated with alpha-importin:beta-importin is transloc...
DGL-CoA (8,11,14-eicosatrienoyl-CoA) undergoes desaturation ...
DHA is transported back to the ER, where it is incorporated ...
DHA-CoA preferentially moves back to the ER, perhaps as a fr...
DHCA (25(R) 3alpha,7alpha-dihydroxy-5beta-cholestanoate) , c...
DHCA (25(R) 3alpha,7alpha-dihydroxy-5beta-cholestanoate), co...
DHCA (3alpha, 7alpha-dihydroxy-5beta-cholestanoate) is trans...
DHHC-21 is a Golgi-localized acyl transferase that palmitoyl...
DHX36 and DHX9 are aspartate-glutamate-any amino acid aspart...
DHX36 senses CpG-A in cytosol of human plasmacytoid dendriti...
DHX9 binds CpG-B in human plasmacytoid dendritic cells (pDC)...
Diacylglycerol (DAG) is an important source of arachidonic a...
Diacylglycerol (DAG) positively regulates the autophosphoryl...
Diacylglycerol kinases (DGKs) are intracellular lipid kinase...
Diacylglycerol lipase (DAGL) hydrolyzes diacylglycerol (DAG)...
Diacylglycerol O-acyltransferase 1 (DGAT2) associated with t...
Diacylglycerol, produced by PLC beta-mediated PIP2 hydrolysi...
DIAPH1 is activated by binding of the DIAPH1 dimer to GTP-bo...
Dicer is an RNase III enzyme which cleaves double-stranded R...
Dietary cholesterol is taken up into enterocytes from the gu...
Dietary cholesterol is taken up into enterocytes from the gu...
Dietary lipids such as long-chain triacylglycerols and chole...
Dietary phytosterols (sterols derived from plants) are taken...
Different ligands of the MOR receptor can promote MOR phosph...
Digoxin is a commonly prescribed drug for the treatment of h...
Dihydroorotate dehydrogenase catalyzes the oxidation of dihy...
Dihydroorotate dehydrogenase catalyzes the oxidation of dihy...
Dihydroxyacetone phosphate (DHAP) is converted to 1-acyl gly...
Dihydroxyacetone phosphate (DHAP) is converted to glycerol-3...
Dihydroxybenzoate is a typical substrate for Catechol O-meth...
Dilysocardiolipin (DLCL) transports via membrane contact sit...
Dimeric cytosolic transaldolase (TALDO1) catalyzes the rever...
Dimeric cytosolic transaldolase (TALDO1) catalyzes the rever...
Dimerization and autophosphorylation at T298 is required for...
Dimerization of the N-terminal luminal regions of IRE1-alpha...
Dimers of ERBB2 and EGF-bound EGFR trans-autophosphorylate o...
Dimers of the T1R1 and T1R3 receptors responds to the umami ...
Dipeptidyl Peptidase IV (DPP4) cleaves 2 amino acids from th...
Dipeptidyl Peptidase IV (DPP4) cleaves 2 amino acids from th...
Diphosphoinositol polyphosphate phosphohydrolase 2, also kno...
Diphosphoinositol polyphosphate phosphohydrolases (DIPP), al...
Diphosphoinositol polyphosphate phosphohydrolases (DIPP), al...
Diphosphoinositol polyphosphate phosphohydrolases (DIPP), al...
Diphosphoinositol polyphosphate phosphohydrolases, also know...
Diphtheria is a serious, often fatal human disease associate...
Diphtheria toxin fragments A and B, linked by a disulfide bo...
Direct binding assays with radiolabeled substrate showed tha...
Direct binding between XWnt11 and XFzd7 has been demonstrate...
Direct binding of GRB2:GAB1:PIK3R1 complex to phosphorylated...
Direct binding of GRB2:GAB1:PIK3R1 complex to phosphorylated...
Direct binding of GRB2:SOS1 complex to phosphorylated homodi...
Direct binding of GRB2:SOS1 complex to phosphorylated homodi...
Direct interactions between the histone H1 C-terminal domain...
Disassembly Phase
The AAA-ATPase, Vps4 disassembles ESC...

Discoidin domain receptors (DDRs) are a subfamily of recepto...
Discoidin domain receptors (DDRs) are a subfamily of recepto...
Diseases of glycosylation, usually referred to as congenital...
Displacement of the APC:CTBP:beta-catenin:betaTrCP complex a...
Disruption of normal Watson-Crick base pairing and altered c...
Dissociation from SUFU allows the STK36/dFu homologue ULK3 t...
Dissociation from the activated receptor quickly follows pho...
Dissociation of Ca2+/CaM from activated CAMK2 allows subsequ...
Dissociation of HSP90 from ERBB2 upon formation of ERBB2 het...
Dissociation of paused ternary complexes requires the Polyme...
Dissociation of the LDL:LDLR complex in the early endosome f...
DKK1, 2 and 4 are secreted antagonists of WNT signaling that...
DLK1 is a Delta-like transmembrane protein with six extracel...
DLL1 binds to NOTCH1 HD (heterodimerization) domain mutants,...
DLL1, expressed on the surface of a neighboring cell, binds ...
DLL4, expressed on a neighboring cell, binds NOTCH2 receptor...
DM GRASP/ALCAM/BEN is one of the heterodimerizing partners ...
DNA damage can be directly reversed by dealkylation (Mitra a...
DNA damage induced activation of the checkpoint kinases Chk...
DNA damage sensor, meiotic recombination 11 homolog A (MRE11...
DNA Fragmentation Factor (DFF), is a heterodimer of 40 kDa (...
DNA fragmentation in response to apoptotic signals is achiev...
DNA in cells is susceptible to different types of cytotoxic ...
DNA Ligase 1 ligates the newly synthesized fragment to the g...
DNA ligase I (LIG1) binds DNA polymerase beta (POLB) at the ...
DNA ligase seals the newly synthesized repair patch to the i...
DNA methyltransferases (DNMTs) associate with EZH2 of the P...
DNA polymerase alpha:primase is comprised of four subunits, ...
DNA polymerase beta (POLB) cannot excise oxidatively damaged...
DNA polymerase beta (POLB) catalyzes DNA strand displacement...
DNA polymerase beta (POLB) is recruited to the AP (apurinic/...
DNA polymerase delta synthesizes DNA across a single-strande...
DNA polymerase eta (POLH) belongs to Y family of DNA polymer...
DNA polymerase eta (POLH) consists of 713 amino acids and ca...
DNA polymerase eta (POLH) correctly incorporates two adenine...
DNA polymerase iota (POLI) has an active site that favours H...
DNA polymerase iota (POLI) is a Y family DNA polymerase with...
DNA polymerase iota (POLI) is recruited to DNA damage sites ...
DNA polymerase kappa (POLK) can elongate mispaired primer te...
DNA polymerase kappa (POLK) forms a quaternary complex with ...
DNA polymerase kappa (POLK) is a Y family DNA polymerase tha...
DNA polymerase kappa (POLK) is the most efficient in incorpo...
DNA polymerases are not capable of de novo DNA synthesis and...
DNA polymerases are not capable of de novo DNA synthesis and...
DNA repair is a phenomenal multi-enzyme, multi-pathway syste...
DNA repair is required to maintain the integrity of the cell...
DNA Replication is regulated accurately and precisely by var...
DNA replication is regulated at various levels via ORC prote...
DNA replication pre-initiation in eukaryotic cells begins wi...
DNA synthesis occurs in the S phase, or the synthesis phase,...
DNA synthesis occurs to fill in remaining single-stranded ga...
DNA-dependent protein kinase (DNA-PK), a member of PI3-kinas...
DNA-dependent serine/threonine protein kinase DNA-PK is a DN...
DNA-PKcs is recruited to the Ku-DNA end complex (Gottlieb an...
DNAX activation protein of 12kDa (DAP12) is an immunorecepto...
DNER is a transmembrane protein specifically expressed in de...
DNMT1 transfers a methyl group from S-adenosylmethionine to ...
Dnmt1 transfers a methyl group from S-adenosylmethionine to ...
Dnmt3a methylates the 5 position of cytosine in DNA preferen...
DNMT3A methylates the 5 position of cytosine in DNA. As infe...
DNMT3B methylates the 5 position of cytosine in DNA. DNMT3B ...
Dnmt3b methylates the 5 position of cytosine in DNA. Dnmt3b ...
DNMT3L is a non-catalytic homologue of DNMT3A and DNMT3B whi...
Dnmt3l is a non-catalytic homologue of Dnmt3a and Dnmt3b whi...
Dnmtl associates with Dnmt3b (Van Emburgh and Robertson 2011...
Dock/Nck bound to Robo recruits Pak to specific sites at the...
Docking and priming of clathrin sculpted acetylcholine loade...
Docking and priming of clathrin sculpted Noradrenaline loade...
Docking occurs once the synaptic vesicle has moved from the ...
Docking of Cx43 at the plasma membrane may involve ZO-1 as ...
Docosapentaenoyl-CoA is elongated to tetracosapentaenoyl-CoA...
Docosatetraenoyl-CoA is elongated to tetracosatetraenoyl-CoA...
Dodecanoic acid (DDCX aka lauric acid) is a medium-chain fat...
Dok-2 is a member of a docking proteins class, termed the DO...
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransfera...
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransfera...
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransfera...
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransfera...
Dolichol is a polyisoprenol lipid comprised of five-carbon i...
Dolichol kinase (DOLK, TMEM15) mediates the phosphorylation ...
Dolichyl phosphate D-mannose (DOLPman) is flipped in the end...
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransfe...
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransfe...
Dolichyl-phosphate beta-glucosyltransferase (ALG5) associate...
Dolichyl-phosphate-glucose functions as a donor of glucose g...
Dolichyl-phosphate-glucose is flipped toward the luminal sid...
Dolichyl-phosphate-mannose (DPM, DOLPman) is the donor of ma...
Dominant mutations in the fibroblast growth factor receptor ...
Dopa is a substrate of tyrosinase, which can oxidize it to ...
Dopachrome is converted to DHICA by DCT (Dopachrome tautomer...
Dopachrome spontaneously tautomerizes into 5,6-dihydroxyindo...
Dopamine beta-hydroxylase (DBH; dopamine beta-monooxygenase)...
Dopamine in the cytosol is metabolized to 3-methoxytyramine ...
Dopamine is oxidized to 3,4-dihydroxyphenylacetic acid by mo...
Dopamine is transported from the cytosol into the reacidifi...
Dopamine loaded synaptic vesicles are docked, inside the syn...
Dopamine neurotransmitter cycle occurs in dopaminergic neuro...
Dopamine once taken up by the dopamine transporter from the ...
Dopamine receptors 1 (Dearry A et al, 1990) and 5 (Sunahara ...
Dopamine receptors 2 (Grandy DK et al, 1989), 3 (Giros B et ...
Dopamine receptors play vital roles in processes such as the...
Dopamine- and cAMP-regulated phosphoprotein, Mr 32 kDa (DARP...
Dopaquinone is highly reactive and in the absence of sulfhyd...
DOT1L is capable of catalyzing mono-, di-, and trimethylatio...
DOT1L is capable of catalyzing the mono-, di-, and trimethyl...
DOT1L is responsible for the mono-, di-, and trimethylation ...
Double Fgf10/Hnf6 KO studies have shown that these two prote...
double-stranded DNA oligonucleotide of 45 bases without CpG
Doublecortin is a microtubule associated protein expressed i...
Down-regulation of CD28 receptors involves a dileucine-based...
Down-regulation of CD28 receptors involves a dileucine-based...
Down-regulation of MHC class I involves Nef-mediated connect...
DP1 is a G-protein-coupled receptor encoded by the PTGDR gen...
DPP (also called “phosphophoryn”) is a highly acidic protein...
DREAM complex is evolutionarily conserved and is reponsible ...
DRIP co-activator complex and assembly

The DRIP co-ac...

Drosophila homolog of RAB6, Rab6, was isolated as the produc...
DSCAM (Down syndrome cell adhesion molecule) is one of the m...
DSCAM and DCC (Deleted in Colorectal Carcinoma) form a recep...
DSCAM and DSCAML1 proteins are involved in homophilic interc...
DSCAM binds netrin-1 and directs the turning of axons toward...
DSCAM can stimulate the activation of JNK, one of the downst...
DSCAM directly binds to serine/threonine-protein kinase PAK1...
dsDNA:AIM2 clusters bind ASC via a PYD-PYD interaction.
DSIF is a heterodimer consisting of hSPT4 (human homolog of ...
Dual incision at defined positions flanking the DNA damage i...
Dual incisions are carried out by XPG, and ERCC1-XPF comple...
Due to alternative splicing, prepro-des-Gln14-ghrelin is mis...
Due to the antiparallel nature of DNA, DNA polymerization is...
Due to the crowded envirnoment within the cell, many protein...
Due to the rarity of this disease, only approximately 20 mut...
Due to their abundance in Mycobacteria, lipids fulfill a buf...
During attenuation and recovery from heat shock, increased l...
During certain types of apoptosis, activated tBID (p15) indu...
During embryogenesis, committed epithelial cells from the ea...
During endocytosis the EPH-ephrin (EFN) intact complex and, ...
During G1 phase of the cell cycle, cyclin A is synthesized a...
During G1, the activity of cyclin-dependent kinases (CDKs) i...
During G1, the activity of cyclin-dependent kinases (CDKs) i...
During G1, the activity of cyclin-dependent kinases (CDKs) i...
During initiation the double-stranded DNA must be melted and...
During interphase, cyclin B1 shuttles continuously in and ou...
During interphase, cyclin B1:Cdc2 shuttles continuously in a...
During interphase, Nlp interacts with gamma-tubulin ring com...
During interphase, phopshorylated Cdc25C is associated with ...
During meiosis the replicated chromosomes of a single diploi...
During normal translation termination eRF3 associates with t...
During POLB-dependent long patch base excision repair (BER),...
During prophase, the chromatin in the nucleus condenses, and...
During reverse transcription, APOBEC3G-mediated minus-strand...
During steady state conditions, cytoplasmic [Ca2+] is reduce...
During the development process cell migration and adhesion a...
During the early stages of mitosis, Cdc2 and PLK1 cooperate ...
During the extracellular proteolytic activation of PDGF-C an...
During the phosphorylation of the IKK beta, the regulatory s...
During the synthesis of actin and tubulin, the nascent ribos...
DVL is a central component of WNT signaling that plays roles...
DVL is recruited to the plasma membrane through a direct int...
DVL protein levels are regulated by both proteasomal and lys...
DVL proteins from Drosophila, Xenopus, mouse and human cells...
DVL1 and 3 have been shown to co-immunoprecipitate with PIP5...
DVL1 is ubiquitinated by HECW1 in Neuro2 cells.
DVL2 is phosphorylated upon WNT5A stimulation of HEK293 cell...
DVL2 is recruited to the WNT5A:FZD4 receptor complex as asse...
Dynamin is a microtubule-associated force-producing protein ...
Dynamin is a neuronal phosphoprotein and a GTPase enzyme whi...
Dynamin is recruited to the growing lysosome destined vesicl...
Dynamin is recruited to the growing vesicle and, under condi...
Dystroglycan (DG) is a cell-surface laminin receptor. In ske...
Dystroglycan (DG) is a cell-surface laminin receptor. In ske...
Dystroglycan binds specifically to a subset of neurexin LNS ...
Dystroglycan binds specifically to a subset of neurexin LNS ...
E-3810 is a dual VEGFR and FGFR inhibitor that has anti-angi...
E-cadherin (CDH1) localizes to the lateral membrane of diffe...
E-cadherin (CDH1) localizes to the lateral membrane of diffe...
E-cadherin (CDH1) localizes to the lateral membrane of diffe...
E-cadherin (CDH1) localizes to the lateral membrane of diffe...
E-cadherin (CDH1) localizes to the lateral membrane of diffe...
E-cadherin is cleaved close to the transmembrane region by p...
E-cadherin, memeber of the cadherin superfamily is a calcium...
E-selectin is an adhesion molecule on the cell surface of en...
E2F1 and E2F3 are able to bind to the NOTCH1 promoter and ac...
E2F1 binds to E2F binding sites on the genome activating the...
E2F1 directly stimulates the transcription of BBC3 (PUMA) (H...
E2F1 directly stimulates the transcription of PMAIP1 (NOXA) ...
E2F1 was directly shown to activate the transcription from t...
E2F1, E2F2 or E2F3 forms a complex with the transcription fa...
E2F1, E2F2 or E2F3 in complex with SP1 stimulates p14-ARF tr...
E2F1, E2F2, E2F3 and E2F4 are all able to bind the promoter ...
E2F1, in complex with TFDP1 (DP-1), binds the promoter of BB...
E2F1, in complex with TFDP1 (DP-1), binds the promoter of PM...
E3 ubiquitin ligase CHIP (STUB1) mediates ERBB2 ubiquitinati...
E3 ubiquitin ligase Cullin-5 (CUL5) is recruited to the ERBB...
E3 ubiquitin ligase NEDD4 binds intracellular domain of ERBB...
E3 ubiquitin ligase NEDD4 mediates ubiquitination of ERBB4 J...
E3 ubiquitin ligase RNF111 (Arkadia) binds SMAD7 in the nucl...
E3 ubiquitin protein ligase TRIM33 (also known as Ecto, Ecto...
E3 ubiquitin-protein ligase TRIM32 and TRIM56 were shown to ...
E3 ubiqutin ligases RNF111 (Arkadia) (Levy et al. 2007, Naga...
E7080 is a broad-specificity tyrosine kinase inhibitor that ...
Each AMPA receptor subunit binds one glutamate molecule in t...
Each AMPA receptor subunit binds one glutamate molecule in t...
Each molecule of Epac1 binds 1 molecule of cAMP. Epac1 binds...
Each molecule of Epac2 binds 2 molecules of cAMP. Epac2 bind...
Each of the four TCF/LEF transcription factors have been sho...
Each of the GLI proteins can form a complex in the nucleus w...
Each protein kinase C related kinase - PKN1 (PRK1), PKN2 (PR...
Early cell cycle progression in G1 is under the control of t...
Early experiments in frog and other species determined that ...
Early studies suggested that NOD1 and NOD2 responded to lipo...
EARS2 (mitochondrial glutamyl tRNA synthetase) catalyzes the...
Ebola virus VP40 virus-like particles (VLPs) requires the in...
Ectopic expression of Xwnt5a or Rfz2 in Xenopus embryos resu...
EED gene contains several E2F binding sites in its promoter,...
EF (edema factor), transported to the cytosol of the target ...
Effects of IFNs result from induction of a subset of genes, ...
Efficient transcript production requires efficient release o...
Efficient transcript production requires efficient release o...
EGF (and indeed FGF, PDGF and NGF) stimulation results in CB...
EGF and other growth factors induce oligomerization of their...
EGFR kinase domain mutants need continuous association with ...
EGFR kinase phosphorylates the phosphorylation sites tyrosin...
EGFR L858R mutant was shown to directly phosphorylate CBL on...
EGFR ligand-responsive mutants dimerize spontaneously, witho...
EGFR phosphorylates PLC-gamma1, thus activating it.
EGFR V30_R297delinsG mutant of EGFR, commonly known as EGFRv...
EGFRvIII (EGFR V30_R297delinsG) is the most prevalent EGFR v...
EGFRvIII cancer mutant was not directly tested for its abili...
EGFRvIII mutant lacks the ligand binding domain and is there...
EGFRvIII mutant lacks the ligand binding domain and is there...
Ehlers–Danlos syndrome (EDS) is a group of inherited connect...
EHMT1 (GLP) and EHMT2 (G9a) histone methyltransferases dimet...
EHMT1 (GLP) and EHMT2 (G9a) histone methyltransferases dimet...
EHMT2 (KMT1C, G9A) and EHMT1 (KMT1D, GLP) are the euchromati...
EHMT2 (KMT1C, G9A) and EHMT1 (KMT1D, GLP) are the euchromati...
Eicosanoids, derived from polyunsaturated 20-carbon fatty ac...
Eicosanoids, oxygenated, 20-carbon fatty acids, are autocrin...
Eicosapentaenoyl-CoA (EPA-CoA) is transformed to docosapenta...
Eicosatetraenoyl-CoA (ETA-CoA) is desaturated by an addition...
eIF2B is a guanine nucleotide releasing factor that is requi...
eIF3 and eIF1A bind to the 40S ribosomal subunit. ...
eIF4A interacts with eIF4G, and eIF4E interacts with the ami...
eIF4B is a physiologically relevant target of S6K1. Once pho...
eIF4E gets released from the inactive eIF4E:4EBP complex. ...
Eight enzymes are involved in heme biosynthesis, four each i...
Eight enzymes are involved in heme biosynthesis, four each i...
Eight SLC gene families are involved in the transport of ami...
Either FURIN or PACE4 endoproteases cleave the 321 amino aci...
Either IGF1 (IGF-I) or IGF2 (IGF-II) can bind the type 1 ins...
Either of GPAM or GPAT2 (glycerol-3-phosphate acyltransferas...
Elastic fibres (EF) are a major structural constituent of dy...
Elastin degradation is regulated by the membrane-associated ...
Elastin microfibril interface located protein (EMILIN)-1 is ...
Elastin microfibril interface located protein (EMILIN)-1 is ...
Elastin, the highly insoluble core protein of elastic fibers...
Electrical synapses are found in all nervous systems, includ...
Electrical transmission across nerve cells is accomplished w...
Electron transfer flavoprotein, ETF, a 63kDa heterodimer com...
Elongation of very long chain fatty acids protein 7 (ELOVL7)...
Elongation of very long chain fatty acids proteins 1, 2, 3 a...
Elongation of very long chain fatty acids proteins 1, 4 (ELO...
Elongator Protein 3 (ELP3) is the catalytic subunit of the h...
Elongator Protein 3 (ELP3, KAT9) is the catalytic subunit of...
Embryonic fibroblast cells from TBK1-deficient mice show dec...
Emi1 destruction in early mitosis requires the SCF beta-TrCP...
Emi1 is also believed to be phosphorylated by Cyclin B:Cdc2 ...
Emi1 promotes the accumulation of Cyclin A and entry into S ...
Ena is required in part for Robo's repulsive output. Ena is ...
Ena/VASP proteins enhance actin filament elongation via the ...
Endocytic compartments contain many cysteine proteases such ...
Endocytosed antigens must leave the endocytic structure to e...
Endocytosis is followed by the vesicular transport and recyc...
Endocytosis of iron loaded transferrin/receptor complex lead...
Endofin is a FYVE domain-containing protein that strongly re...
Endogenous DVL2 and 3 are phosphorylated upon stimulation of...
Endogenous MAP3K7 is phosphorylated in a CAMK2-dependent fas...
Endogenous Notch2 and Cntn1 (F3 i.e. contactin-1) can be co-...
Endogenous retinoic acids (RA) which play a role in gene reg...
Endogenous STAT6 was found to co-fractionate with STING from...
Endogenous UCHL5 and SMAD7 were shown to form a complex in h...
Endonucleolytic cleavage separates the pre-mRNA into an upst...
Endonucleolytic cleavage separates the pre-mRNA into an upst...
Endoplasmic reticulum calcium ATPases are required for maint...
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-man...
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-man...
Endoplasmic reticulum resident protein 57 (ERp57), is a memb...
Endorepellin is the 85-kDa C-terminal domain V of HSPG2 (per...
Endorepellin is the C-terminal domain V of perlecan, constit...
Endorepellin is the C-terminal domain V of perlecan, constit...
Endosomal recognition of influenza genomic RNA and imidazoqu...
Endosome maturation (acidification) is required for both the...
Endostatin binds to the integrins alphaVbeta3, alphaVbeta5, ...
Endostatin is an anti-angiogenic and motility-inducing facto...
Endothelins are 21-amino acid vasoconstricting peptides prod...
Energy for the phosphorylation of APS comes from the hydroly...
Enhancer of split, a Drosophila orthologue of HES, is a basi...
eNOS activity is regulated by numerous post-translational mo...
eNOS interacts with the SH3 domain of NOSTRIN (positions 434...
eNOS traffic inducer (NOSTRIN) is a novel 506-amino acid eNO...
eNOS-interacting protein (NOSIP) is a 34-kDa nucleocytoplasm...
Entry of cofactor C to the factor E:alpha tubulin: factor D:...
Enzyme misfolding due to missense mutations results in incor...
Enzymes that belong to the NUDT (Nudix) superfamily catalyze...
EP3 receptor mRNA are subject to alternative splicing at the...
EP300 and the related CREBBP are transcriptional regulators ...
EP400 (p400) binds to a CDKN1A promoter region that overlaps...
EPAC1 and EPAC2 are activated by binding cAMP and positively...
Epac1 is activated by binding cAMP, forms a complex with inw...
Epac2 is activated by binding cAMP, forms a complex with inw...
EPACs (exchange proteins directly activated by cAMP) are Rap...
EPAS1 (HIF2A) enhances expression of NANOG by an unknown mec...
EPAS1 (HIF2A) enhances expression of OCT4 (POU5F1) by an unk...
EPAS1 (HIF2A) enhances expression of SOX2 by an unknown mech...
EPH kinase Cek5/EPHB2 phosphorylates tyrosine residue in the...
EPH/Ephrin signaling is coupled to Rho family GTPases such a...
EPHB receptor-induced phosphorylation of coffin is at least ...
EPHB2-C-terminal fragment1 (CTF1) is subsequently cleaved wi...
EPHBs are involved in spine synapse formation and also for t...
Ephexin1/NGEF (Neuronal guanine nucleotide exchange factor) ...
Epidermal fatty acid-binding protein (FABP5) is a cytosolic,...
Epidermal fatty acid-binding protein (FABP5) is a cytosolic,...
Epigenetic processes regulate gene expression by modulating ...
Epinephrine causes hyperpolarization of pancreatic beta cell...
Epithelial cell-cell contacts consist of three major adhesio...
EPM2A (laforin) associated with cytosolic liver- and muscle-...
EPM2A (laforin) binds to the PPP1R3C:phosphoglycogen-GYG1 (g...
EPM2A (laforin) binds to the PPP1R3C:phosphoglycogen-GYG2 (g...
EPM2A (laforin), associated with PPP1R3C (protein phosphatas...
EPM2A (laforin), associated with PPP1R3C (protein phosphatas...
Epoxide hydrolase 2 (EPHX2) hydrolyses 5,6-, 8,9-, 11,12-, a...
Epsin directly modifies membrane curvature on binding to PIP...
Equilibrium between 5'-methylthio ribose-1-phosphate and 5'...
ER membrane-bound sphingomyelin phosphodiesterase 4 (SMPD4) ...
ERBB2, also known as HER2 or NEU, is a receptor tyrosine kin...
ERBB2, which does not bind any known ligand, is activated th...
ERBB2:EGFR and ERBB2:ERBB4 can directly recruit GRB2:SOS1 co...
ERBB2:ERBB3 and ERBB2:ERBB4cyt1 heterodimers activate PI3K s...
ERBB3 becomes activated by binding either neuregulin 1 (NRG1...
ERBB4, also known as HER4, belongs to the ERBB family of rec...
ERBB4s80 (E4ICD) binds cytosolic TAB2:NCOR1 complex through ...
ERBB4s80 (E4ICD) bound to cytosolic TAB2:NCOR1 complex media...
ERBB4s80 binds STAT5A through STAT5A SH2 domain. This intera...
ERBB4s80 forms a complex with activated estrogen receptor ES...
ERBB4s80 interacts with a co-transcriptional activator YAP1 ...
ERBB4s80:STAT5A complex binds to and stimulates transcriptio...
ERCC1-XPF complex with 5’ endonuclease activity binds to t...
ERF binds to an ETS-binding site in the ETS2 promoter (Sgour...
ERK/MAPK kinases have a number of targets within the nucleus...
ERK2 phosphorylates cPLA2, increasing enzymatic activity. Th...
ERKs are inactivated by the protein phosphatase 2A (PP2A). ...
Erlotinib (OSI-774, Tarceva) is an EGFR-specific tyrosine ki...
ERp57/ERp27 is a thiol-oxidoreductase that interacts with ca...
ERR1 (ERRalpha) probably interacts with coactivator PG-1beta...
ERR1 (ERRalpha) probably interacts with coactivator PGC-1bet...
ERR1 (ERRalpha) probably interacts with PGC-1beta to activat...
Erythrocytes circulating through the capillaries of the lung...
ESCRT-0 recruits ESCRT-I and thereby initiates the MVB pathw...
ESCRT-III assembles into a highly ordered filament-like hete...
ESPL1 (separin i.e. separase) cleaves RAD21 (SCC1) subunit o...
ETF-ubiquinone oxidoreductase (ETF-QO), catalyzes the re-oxi...
Ethanol and related alcohols can be ingested as part of the ...
ETS1 and ETS2, activated by RAS/RAF/MAP kinase cascade, bind...
Eukaryotic centromeres are marked by a unique form of histon...
Eukaryotic DNA is associated with histone proteins and organ...
Eukaryotic elongation factor 2 (EEF2) catalyzes the GTP depe...
Eukaryotic translation initiation factor 4F (eIF4F) is a pro...
Eumelanin is a stacked, aggregated oligomer, or heterogeneou...
EVC2 and EVC are components of a complex that localizes to t...
Eventually the Schiff base linkage between the all-trans-ret...
Evidence suggests that FZD4 is endocytosed in a clathrin- an...
Evidence suggests that the RNA molecules used for the synthe...
Exact details are unclear but it is assumed once the binding...
Excess homocysteine will change the enzymatic activity of CB...
Exchange of GDP for GTP by the alpha subunit of the heterotr...
Excitatory synaptic transmission in the brain is carried out...
EXO1 exonucleolytically degrades the strand being repaired i...
EXO1 exonucleolytically degrades the strand being repaired i...
EXO1 interacts with MSH2 and MLH1 (and therefore is presumed...
EXO1 interacts with MSH2 and MLH1 (and therefore is presumed...
Exocyst-mediated fusion of the Golgi-derived vesicle deliver...
Exocytosis of insulin-zinc granules occurs by the calcium-de...
Exocytosis of insulin-zinc granules occurs by the calcium-de...
Exogenous antigen loaded class I MHC molecules in phagosomes...
Exogenous antigens are thought to be processed for cross-pre...
Exogenous soluble antigens are cross-presented by dendritic ...
Exogenously expressed human ERBB4s80 binds mouse Tab2:Ncor1 ...
Exogenously expressed human ERBB4s80 mediates translocation ...
Exogenously expressed human GRB2 in complex with mouse Sos1 ...
Exogenously expressed human GRB2 in complex with mouse Sos1 ...
Exostosin 1 and 2 (EXT1 and 2) are dual specificity enzymes ...
Exostosin 1 and 2 (EXT1 and 2) are dual-specific glycosyltra...
Exostosin 1 and 2 (EXT1 and 2) are dual-specific glycosyltra...
Exostosin 1 and 2 (EXT1 and 2) are dual-specific glycosyltra...
Exostosin1 and 2 (EXT1 and 2) are dual specificity enzymes w...
Experiments performed on mouse fibroblasts, including both N...
Exportin-5 binds pre-microRNAs having 2-nucleotide overhangs...
Expression of a rat Fzd2- beta adrenergic receptor chimera i...
Expression of ALAS1, the ubiquitous form of delta-aminolevul...
Expression of chicken TLR21 in HEK293 was shown to upregulat...
Expression of FGFR1OP-FGFR1 in both Ba/F3 and Cos-1 cells le...
Expression of Hnf1-beta is markedly reduced in early pancrea...
Expression of HSD17B1 which is the main enzyme that catalyze...
Expression of rRNA genes is coupled to the overall metabolis...
Expression of the CEBPB and CEBPD transcription factors is i...
Expression of the FGFR4 Y367C mutant in MDA-MB453 breast can...
Expression of the GLI1 gene is repressed in the absence of H...
Expression of the GLI2 gene is repressed in the absence of H...
Expression of the integrated HIV-1 provirus is dependent on ...
Expression of the other enzyme catalyzing the sulfhydrylatio...
Expression of the PTCH1 gene is repressed in the absence of ...
Extended cRNA complexed with viral NP and trimeric polymeras...
Extracellular amylose starch, linear polymers of glucose joi...
Extracellular apoA-I protein binds to the CUBN (cubilin) sub...
Extracellular apolipoprotein A-I interacts with phospholipid...
Extracellular Cu-Zn superoxide dismutase (SOD3) catalyzes th...
Extracellular deposition of fibrillin requires removal of th...
Extracellular discoidal HDL particles interact with choleste...
Extracellular glutathione (GSH) can be hydrolysed to give cy...
Extracellular IL4I1 catalyzes the reaction of phenylalanine,...
Extracellular lactose is hydrolyzed to yield molecules of gl...
Extracellular PA83 (full length Protective Antigen - Petosa ...
Extracellular PA83 (full length Protective Antigen - Petosa ...
Extracellular plasminogen binds with high affinity to histid...
Extracellular signal-regulated kinase 5 (ERK5) is a member o...
Extracellular sucrose is hydrolyzed to yield glucose and fru...
Extracellular trehalose, a disaccharide, is cleaved by treha...
EZH2 (KMT6, PRC2) is the catalytic subunit of the PRC2 (EZH2...
EZH2 , a SET domain protein, trimethylates histone H3 at lys...
EZH2 gene contains several E2F binding sites in its promoter...
Ezrin is a member of the ezrin/radixin/moesin (ERM) family t...
Ezrin Radixin Moesin (ERM) are the members of the FERM domai...
F-actin-capping protein binds in a Ca2+-independent manner t...
F-box proteins were first characterized as components of SCF...
F11R (JAM-A) is the most widely expressed member of the fami...
F2R (PAR1) mediates multiple cytoprotective effects of Activ...
FA protein FANCI has been identified as an ATM/ATR kinase su...
Factor A:beta tubulin complex act as a reservoir capable of ...
Factor D, a constitutively active serine protease found in t...
Factor D, a constitutively active serine protease found in t...
Factor E:alpha tubulin and Factor D:beta tubulin interact w...
Factor H (FH) binds to C3bBb, leading to displacement of Bb....
Factor H (FH) regulates the alternative pathway C3 convertas...
Factor H (FH) regulates the alternative pathway C3 convertas...
Factor H accelerates the decay of existing C3/5 convertases ...
Factor H greatly accelerates the displacement (decay) of Com...
Factor H preferentially binds to host cells and surfaces tha...
Factor I (FI) inactivates C3 convertase activity by cleavage...
Factor I cleaves the truncated alpha (a') chain of C4b betwe...
Factor IXa, in a complex with factor VIIIa on the surfaces o...
Factor TFIIE enters the preinitiation complex after TFIIF re...
Factor VII, bound to tissue factor at the endothelial cell s...
Factor VII, the protease that initiates the normal blood clo...
Factor VIIa, bound to tissue factor at the endothelial cell ...
Factor VIIa, bound to tissue factor at the endothelial cell ...
Factor VIII binds to von Willebrand factor to form a complex...
Factor VIII complexed to von Willibrand factor in the blood ...
Factor Xa catalyzes the activation of factor VII from plasma...
Factor XI, bound to the cell surface, is converted to activa...
Factor XI, bound to the cell surface, is converted to activa...
Factor XIa, bound to platelet glycoprotein (GP) Ib:IX:V on t...
Factors Va and Xa associate on a membrane surface to form a ...
Factors VIIIa and IXa associate on cell surfaces to form a c...
FAD-linked mitochondrial glycerol 3-phosphate dehydrogenase ...
FADD (FAS-associating death domain-containing) protein binds...
FADD recruits caspase-10 precursor (pro-caspase-10) to FASL:...
FADD recruits caspase-8 precursor to trimeric complex of TRA...
FADK1 interacts with the C-terminal P3 domain of DCC complex...
FAK is a tyrosine kinase that localizes to focal adhesions a...
FAK-mediated spine morphogenesis was shown to occur, in part...
FANCI is monoubiquitinated on lysine 523 in an FA core-com...
FANCI phosphorylation may function as a molecular switch to ...
Fanconi anemia (FA) is a genetic disease of genome instabili...
Fanconi anemia (FA) is a rare hereditary disorder characteri...
Fanconi anemia (FA) is a rare human hereditary disorder char...
Farnesyl diphosphate farnesyltransferase (FDFT; squalene syn...
FARS (cytosolic phenylalanyl tRNA synthetase) catalyzes the ...
FARS2 (mitochondrial phenylalanyl tRNA synthetase) catalyzes...
Fas-AssociatedDeathDomain (FADD) and receptor interacting pr...
FASL (FAS antigen ligand) binds FAS receptor (CD95) (Brunner...
Fatty acid cyclo-oxygenase (COX) converts arachidonic acid t...
Fatty acids are the ligands for a small family of G-protein-...
Fatty acids augment the glucose triggered secretion of insul...
Fatty acids inhibit the secretion of ghrelin by an unknown m...
Fatty acyl-CoA biosynthesis involves following steps:
-P...

FBXL3 is an F-box type component of a particular SKP/CUL/F-B...
Fbxl3 is an F-box type component of a particular SKP/CUL/F-B...
FBXW7 (FBW7) is a component of the SCF (SKP1, CUL1, and F-bo...
FBXW7 (FBW7) mutations are found in ~20% of T-cell acute lym...
FCERI aggregation has been shown to activate JNK as well as ...
FCERI is primarily expressed on mast cells and basophils as ...
FCGR mediated phagocytosis requires CDC42 to stimulate actin...
FCGRI is coded by three different genes (A, B, and C) and is...
FCGRII (CD32) is a low-affinity receptor encoded by three di...
FCGRIII (CD16) is a low affinity Fc gamma receptor and is en...
FCP1 dephosphorylates RNAP II in ternary elongation complexe...
FECH (ferrochelatase) in the mitochondrial matrix catalyzes ...
Ferritin bound to Scara5 (Scara5:ferritin) is taken up by en...
Ferritin oxidises Fe(II) ions to Fe(III), migrates them to i...
Ferrochelatase (FECH) catalyzes the insertion of ferrous iro...
Fes bound to Plexin-A is able to phosphorylate all five form...
FFAR1 (GPR40) is a G-protein coupled receptor. Based on stu...
Fgf10-/- embryos have markedly reduced Ptf1 mRNA expression ...
FGF21 and FGF19 require betaKlotho for efficient signaling t...
FGF23 is a member of the endocrine subfamily of FGFs. It is ...
FGFR is one of the heterophilic interactors of NCAM. The FG ...
FGFR1 fusions with ZMYM2, BCR, FGFR1OP and TRIM24 all result...
FGFR1 gain-of-function mutations at P252 that result in incr...
FGFR1-amplified cells derived from lung cancer patients show...
FGFR1-amplified lung cancer and breast cancer cells show str...
FGFR2 amplifications have been identified in 10% of gastric ...
FGFR2 is inhibited by a range of in vitro tyrosine kinase in...
FGFR2 S267P undergoes ligand-independent dimerization, and a...
FGFR3 has been shown to be a target of a range of different ...
FGFR3 is a receptor tyrosine kinase of the FGF receptor fami...
FGFR3 P350R is associated with the development of Muenke syn...
FGFR4 is expressed mainly in mature skeletal muscle, and dis...
FGFR4 is highly expressed in rhabdomyosarcoma (RMS) tissue, ...
FGFR4 is perhaps the least well studied of the FGF receptors...
FGFR4 N535K and FGFR4 V550E have been shown to undergo autop...
Fibrillar collagen is synthesized in the ER as procollagen w...
Fibrillar collagen is synthesized in the ER as procollagen w...
Fibrillin microfibril assembly is a cell regulated process, ...
Fibrillin-1 can be degraded by MMP3 (Ashworth et al. 1999) a...
Fibrillin-1 is the major structural component of microfibril...
Fibrillin-1 splice variants that include the RGD sequence lo...
Fibrillin-1, the major structural component of microfibrils ...
Fibrillin-1, the major structural component of microfibrils ...
Fibrillins are the main constituents of the extracellular mi...
Fibrillins can bind the prodomains of TGF-beta superfamily m...
Fibrils are components of larger suprafibrillar structures, ...
Fibrin is a hexamer of two fibrinogen alpha chains, two fibr...
Fibrin monomers rapidly and spontaneously associate into lar...
Fibrin multimers are stabilized by the formation of multiple...
Fibrinogen is a hexamer, containing two fibrinogen alpha cha...
Fibronectin (FN1) binds many types of collagen, particularly...
Fibronectin (FN1) is found in the extracellular matrix (ECM)...
Fibronectin plays a role in cell adhesion and cell migration...
Fibulins are a family of 7 extracellular calcium binding pro...
Fibulins are a family of 7 genes encoding calcium binding gl...
Ficolin-1 (M-ficolin or FCN1) was shown to localize at the c...
Ficolin-3 (H-ficolin, FCN3 or Hakata antigen) activates the ...
Ficolins are recognition molecules in the lectin complement ...
Finally, progression out of mitosis and division of the cell...
First, IRAK1 is phosphorylated at Thr209 by IRAK4. This resu...
Fission yeast expresses two kinesin-8s. These polypeptides c...
Five EDG-encoded receptors can all bind sphingolipid-1-phosp...
Five human SLC13 genes encode sodium-coupled sulphate, di- a...
Five SLC gene families encode proteins that mediate transpor...
Five subunits (alpha, beta-1, beta-2, gamma-1, gamma-2) asse...
FLAG-tagged mouse Pard6a exogenously expressed in human embr...
Flavin-containing monooxygenases (FMOs) are the second famil...
FMN can be phosphorylated and adenylated to produce the seco...
FMNL1 (formin-like protein 1) binds the active, GTP-bound, f...
FMNL1 binds activated CDC42 and this interaction is implicat...
FMNL1, activated by binding to GTP-bound RAC1, binds actin-a...
FMNL2 binds activated (GTP-bound) CDC42. FMNL2 can be myrist...
FMNL2 specifically interacts with the GTP-bound RHOC, which ...
FMNL3 binds activated (GTP-bound) RHOC. RHOC-mediated activa...
Focal adhesion kinase 1 (PTK2, FAK, FAK1) activation plays a...
Focal adhesion kinase 1 (PTK2, FAK, FAK1) acts downstream of...
Folates are essential cofactors that provide one-carbon moie...
Folded TLR9 dissociates from GP96:CNPY3 complex (Liu B et a...
Follicle-stimulating hormone (FSH) is a dimeric glycoprotein...
Follicle-stimulating hormone (FSH, follitropin) is a hormone...
Follow their formation, the Cyclin E:Cdk2 complexes are tran...
Following 26S-proteasomal processing, NFKB2 p52:RELB dimer i...
Following activation, AKT can phosphorylate an array of targ...
Following association with KIT, Tauchi et al. had observed p...
Following branch migration, the invading 3’ resected ends ...
Following caspase mediated cleavage, PAK-2p34 translocates t...
Following caspase-3 cleavage, the fragments of DFF45 dissoci...
Following CKI-mediated phosphorylation at Ser45, beta-cateni...
Following cleavage of the damaged base, DNA glycosylase is d...
Following cleavage of the damaged base, DNA glycosylase is d...
Following connexon oligomerization, the hemichannels must be...
Following double strand break (DSB) formation and strand res...
Following double strand break (DSB) formation and strand res...
Following exposure to ionizing radiation, a number of recomb...
Following fission of the phagosome vesicle from the plasma m...
Following iinduction of apoptosis in epithelial cells, tight...
Following IL-6 stimulation, SHP2 is recruited to gp130 phosp...
Following IL2 stimulation of IL2R, Shc is known to be tyrosi...
Following initial activation autoproteolysis occurs at Glu10...
Following initiating proteolytic cleavage by serine protease...
Following its association with SCF-βTrCP, phospho-Emi1 is po...
Following its dephosphorylation in late mitosis, Cdh1 replac...
Following its phosphorylation, Cdh1 dissociates from the APC...
Following its release from DFF45, DFF40 forms homodimers, wh...
Following its translocation to the nucleus, Cdc25 dephosphor...
Following ligand binding, EPH signaling is initiated through...
Following multi-ubiquitination by the Vif-Cul5-SCF complex, ...
Following multiubiquitination, Cyclin A is targeted for dest...
Following NGF binding, p75NTR activates the RAC (Ras-related...
Following nuclear entry, the viral preintegration complex (P...
Following peptide bond formation, GTP-bound eEF2 catalyzes t...
Following phosphorylation of the APC/C core subunits by mito...
Following phosphorylation, STATs are released from the recep...
Following receptor activation, PAR1 complexes with beta-arre...
Following recruitment to the DISC, FLIP(L) forms a heterodim...
Following repair synthesis, the extended strands may disasso...
Following stimulation by IL2, the IL2R beta chain become pho...
Following synthesis on membrane-bound ribosomes, the three v...
Following the association of BP180 with the forming hemidesm...
Following the association of Rev with importin-beta, the Re...
Following the detection of DSBs, ATM mediates the phosphoryl...
Following the detection of DSBs, ATM mediates the phosphoryl...
Following the displacement of Bb from C3bBb, Factor I cleave...
Following the formation of cysteinyldopa (CD) isomers, pheom...
Following the integrase-mediated strand transfer reaction of...
Following the synthesis of new DNA at resected 5' ends of th...
Following translocation to the nucleus, ERK1/2 directly phos...
Following tyrosine phosphorylation and activation, PLCG1 dis...
Following tyrosine phosphorylation and dimerization STAT6 tr...
Following tyrosine phosphorylation, phospholipase C-gamma 2 ...
Following ubiquitination by the SCF(Skp2):Cks1 complex, phos...
Following ubiquitination Ikappa B-alpha (IKBA) is rapidly de...
Following ubiquitination, securin is degraded by the 26S pro...
Following VEGF treatment, VAV2 phosphorylation on tyrosine 1...
Foot processes are long slender, actin rich protrusions of t...
For a budding influenza virus to be fully infectious is it e...
For centuries influenza epidemics have plagued man, and infl...
For each of eight gene segments, a viral ribonucleoprotein (...
For most influenza A strains (such as PR8), the PB1 mRNA seg...
For retroviral DNA to direct production of progeny virions i...
For the reactive metabolite aflatoxin B1-exo-8,9-epoxide (AF...
For the receptor to autophosphorylate requires a lysine at p...
Formation of phosphodiester bonds nine and ten creates RNA ...
Formation of a complex involving NOTCH, Deltex (DTX) and non...
Formation of cytosolic complex of ERBB4s80 and STAT5A promot...
Formation of the hetero-tetrameric BMP2:receptor complex ind...
Formation of the hetero-tetrameric TGF-beta-1 receptor compl...
Formation of the LAT signaling complex leads to activation o...
Formation of the open complex exposes the template strand t...
Formation of the pre-initiation complex...
Formation of the second phosphodiester bond creates a 3-nt p...
Formation of the second phosphodiester bond creates a 3-nt p...
Formation of the third phosphodiester bond creates a 4-nt p...
Formins are a family of proteins with 15 members in mammals,...
Formyl-CoA formed during the alpha-oxidation of phytanoyl-Co...
Formylmycothiol, like any S-formyl ester, is unstable and qu...
FOS:JUN (AP-1) transcription factor stimulates the transcrip...
FOS:JUN (AP-1) transcription factor, formed in response to o...
Four members of the SLC16A gene family encode classical mono...
Four NUDT1 ("MTH1") proteins have been identified, generated...
Four patients with early-onset, life-threatening microbial i...
Four SLC gene families encode proteins that mediate the tran...
Four SLC17 genes are thought to encode type I Na+-dependent ...
Four transporters mediate GABA uptake in the brain, GAT1-3 a...
FOXM1 bound to the MuvB complex (consisting of LIN9, LIN37, ...
FOXM1 bound to the MuvB complex (consisting of LIN9, LIN37, ...
FOXM1 can bind the regulatory subunit B55-alpha (PPP2R2A) of...
FOXM1 stimulates the transcription of the kinetochore protei...
FOXM1, bound to the MuvB complex (consisting of LIN9, LIN37,...
FOXM1, possibly in cooperation with other transcription fact...
FOXO3 (FOXO3A) interacts with phospho-SMAD2 and phospho-SMAD...
FP-1039 is a soluble fusion protein consisting of the extrac...
FP-1039 is an FGFR1c:Fc fragment that acts as a broad FGF- l...
FPRL1 has been reported to respond to numerous ligand with a...
FPRL2 is activated by the neuroprotective peptide humanin, a...
Fragments of extracelllar flagellin bind the TLR5 homodimer.
Frameshift and missense mutations have been identified in th...
Frataxin (FXN) specifically binds 2 atoms of ferrous iron pe...
Free fatty acid receptor 1 (FFAR1), also known as GPR40, is ...
Free fatty acid receptor 1 (FFAR1/GPR40) is activated by man...
Free fatty acid receptor 2 (FFAR2/GPR43) is activated by car...
Free fatty acid receptor 3 (FFAR3/GPR41) is activated by car...
Free fatty acids augment the glucose-triggered secretion of ...
Free glucokinase (GCK1) leaves the nucleus via the nuclear p...
Free heme is damaging to tissues as it intercalates into bio...
Free, nuclear RanGTP is required for export processes out o...
Frequent expression of an internally deleted LRP5 has been i...
Fringe-modified NOTCH functions at the plasma membrane. The ...
From a recent review of mutations for MPSIVA (MIM:253000) (T...
From late mitosis through G1 phase APC/C:Cdh1 insures the c...
From research with human cells (Majumder et al. 2006, Espada...
From the endoplasmic reticulum, the pro-neurotrophins transi...
From the glucanotrehalose, the enzyme TreZ cleaves one molec...
FRS2 (also known as FRS alpha is activated through tyrosine...
FRS2 (also known as FRS2alpha) is broadly expressed in adult...
FRS2 binds to TRKA through the same motif (NPXY) around the ...
FRS2 has 8 canonical MAPK phosphorylation sites which are ph...
FRS3 (also known as FRS2 beta) is activated through tyrosine...
FRS3 (also known as FRS2beta) is predominantly expressed in ...
Fructose is found in fruits, is one of the components of the...
Fructose occurs naturally in foods as a free monosaccharide ...
Fu et al. (2005) report that only lysine-160 is conjugated t...
Full activity of most CDKs is dependent on CAK mediated phos...
Full activity of most CDKs is dependent on CAK mediated phos...
Full length mouse Smad7 was used to screen a human chondrocy...
Full-length 120-kDa CDH1 protein is cleaved in the ectodomai...
Full-length GLI proteins are labile transcription factors th...
Functional GABA B receptors are heteromers of GABA B1 and B2...
Furin is an endopeptidase localized to the Golgi membrane th...
Furin or a related protease at the cell surface cleaves ANTX...
Furin or a related protease at the cell surface cleaves ANTX...
Further condensation of an isopentenyl pyrophosphate with ge...
Fusion of HIV with target cell plasma membranes is mediated ...
Fusion of the maturing phagosome with the ER mediates the ex...
Fyn activation leads to the recruitment and activation of th...
Fyn and Lyn constitutively associate with GPVI-Fc epsilon R1...
Fyn constitutively associates with the 140 kD isoform of NCA...
FYN has multiple phosphorylation sites which can affect its ...
FYN recruited to VEGFR2 is activated; this is required for V...
Fz3 is asymmetrically localized in the membrane of the mouse...
FZD3 shows an asymmetric distribution in the membrane of the...
G alpha q protein (or Gq/11) consists of four family members...
G alpha z (Lounsbury et al. 1991) and G alpha 12 (Kozasa & G...
G alpha-olf:GTP binds to inactive adenylate cyclase, causing...
G beta:gamma engages the PH domain of Phospholipase C beta, ...
G beta:gamma recruits PI3K gamma from the cytosol to the pla...
G protein-coupled estrogen receptor 1 (GPER; CEPR; G-protein...
G protein-coupled receptor 44 (GPR44) is a GPCR that has rec...
G protein-coupled receptors (GPCRs) are classically defined ...
G protein-coupled receptors (GPCRs; 7TM receptors; seven tra...
G proteins are inactive in the GDP-bound state. The ternary ...
G proteins can deactivate themselves via their intrinsic GTP...
G(s)-alpha:GTP binds to inactive adenylate cyclase, causing ...
G-protein coupled receptor family C group 6 member A (GPRC6A...
G-protein-coupled receptor kinase-interacting protein 1 (GIT...
G-protein-coupled receptor kinase-interacting protein 1 (GIT...
G-proteins in the Gi class inhibit adenylate cyclase activit...
G-proteins in the Gi class inhibit adenylate cyclase activit...
G2/M checkpoints include the checks for damaged DNA, unrepli...
GAB1 binds to EGF receptors via tyrosine autophosphorylation...
GAB1 in complex with GRB2 is recruited to activated ERBB2:EG...
GAB1 is recruited to the activated EGFR indirectly, through ...
GAB2 bound to GRB2 on KIT is then phosphorylated on a number...
GAB2 have multiple tyrosyl phosphorylation sites that are ph...
GABA A (rho) receptors are highly expressed in the retina an...
GABA B receptors are coupled to Gproteins and function by in...
GABA B receptors are G protein coupled receptors that are ac...
GABA B receptors are metabotropic receptors that are functio...
GABA is a major inhibitory neurotransmitter in the mammalian...
GABA is converted to succinate semialdehyde by 4-aminobutyra...
GABA is loaded into the synaptic vesicle by inihibitory amin...
GABA is metabolized to succinated by the serial action of tw...
GABA loaded synaptic vesicles are docked at the presynaptic ...
GABA synaptic vesicles are fused to the presynaptic terminal...
GABA synthesized uniquely by two forms of glutamate decarbox...
GAD1 or GAD67 is evenly spread throghout the neuronal cytopl...
GAD65 or GAD2 is concentrated in the nerve terminal region i...
Gads (Grb2-related adaptor protein 2) is essential for CD28 ...
Gads is a member of the Grb2 family containing SH2 and SH3 ...
Gads/GRAP2 (GRB2-related adapter protein 2) is member of the...
GAF transcription factor translocated into nucleus binds to ...
Gag assembly leads to formation of the immature lattice. The...
Gag is translated from the unspliced viral RNA on free ribos...
Galactocerebrosidase (GALC) hydrolyses the galactosyl moiety...
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransf...
Galanin is a 30-amino acid inhibitory neuropeptide encoded b...
Gamma aminobutyric acid (GABA) receptors are the major inhib...
Gamma-aminobutyric acid (GABA) is the chief inhibitory neuro...
Gamma-Aminobutyric acid (GABA) is the major inhibitory
trans...

Gamma-carboxylation of a cluster of glutamate residues near ...
Gamma-glutamylcyclotransferase (GGCT) homodimer (Bae et al. ...
Gamma-glutamylcyclotransferase (GGCT) homodimer can catalyse...
Gamma-glutamylcysteine ligase (GCL) catalyses the first and ...
Gamma-H2AX formation by activated ATM kinase is one of the f...
Gamma-H2AX, formed by activated ATM kinase iasan early respo...
Gamma-linolenoyl-CoA (6,9,12-20:3(n-6)) is rapidly elongated...
Ganglioside-bound tetanus toxin disulfide-bonded heavy chain...
Gangliosides are glycosphingolipids in which oligosaccharide...
Gap junction plaque internalization and the disruption cell ...
Gap junctions are clusters of intercellular channels connect...
Gap junctions are intercellular communication channels forme...
GARS (cytosolic glycyl tRNA synthetase) catalyzes the reacti...
GARS (mitochondrial glycyl tRNA synthetase) catalyzes the re...
GAS1 is a vertebrate-specific Hh coreceptor that binds direc...
Gastric inhibitory polypeptide (GIP, glucose-dependent insul...
Gastric intrinsic factor (GIF) bound to cobalamin (Cbl) is t...
Gastric parietal cells secrete gastric intrinsic factor (GIF...
Gastric parietal cells secrete gastric intrinsic factor (GIF...
Gastrin activated PKC pathway leads to the induction of matr...
Gastrin can induce cleavage of pro-HBEGF via MMP3, releasing...
Gastrin can induce cleavage of pro-Hbegf via stromelysin-1 (...
Gastrin is a hormone whose main function is to stimulate sec...
Gastrin receptors (gastric cholecystokinin B receptor, CCK-B...
Gastrin, through the action of diacylglycerol produced from ...
Gb5L is the long splice variant of the fifth form of G beta ...
Gbetagamma rebinds Galpha-olfactory:GDP, stopping its activi...
GBF1 promotes guanine nucleotide exchange on ARF4 at the Gol...
GDIs sequester the inactive GTPases, preventing the dissocia...
GDP dissociation inhibitors or GDIs confer an additional but...
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase...
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase...
GDP-mannose is the mannose donor for the first 5 mannose add...
Gefitinib (ZD1839, Iressa) is a low-molecular-weight EGFR ty...
Gelatin forms when collagen becomes partly or completely unc...
Gelatin is formed when collagen becomes partly or completely...
Gelsolin is cleaved by caspase-3 generating a constitutivel...
Gene encoding complement regulatory GPI-anchored protein (CR...
Gene Expression covers the pathways by which genomic DNA is ...
Genetic recombination and the repair of double strand DNA br...
Genetic studies in Drosophila have identified Numb as an inh...
Genetic studies in Drosophila identified deltex as a positiv...
Genetic studies in S. cerevisiae indicate that wild-type Cdc...
Genome-wide ChIP studies have identified Hh pathway members ...
Genomic deletions of the entire AMER1/WTX gene occur in abou...
Genotoxic stress caused by DNA damage or stalled replication...
Gephyrin, which stabilizes receptors on neuronal membranes, ...
GFM1 (EF-Gmt, EF-G1mt) of the GFM1:GTP complex hydrolyzes GT...
GFM2:GTP (EF-G2mt:GTP) joins MRRF at the A site of the ribos...
GFMT1:GTP (EF-G1mt:GTP) binds ribosomes possessing a peptidy...
GFRalpha receptors GFRalpha1 and possibly also GFRalpha2 and...
GG-NER is considered to be transcription-independent, removi...
GH has short term effects that mimic the actions of insulin...
GH stimulated tyrosyl phosphorylation of Stats 1, 3, and 5 i...
GHBP is the ectodomain of GHR, cleaved from membrane-bound G...
GHBP, the ectodomain of GHR cleaved from membrane-bound GHR ...
Ghrelin is a 27 or 28 residue long peptide that is the ligan...
Ghrelin is a peptide hormone of 28 amino acid residues which...
GIP is secreted by intestinal K-cells in response to glucose...
GJ plaques, clusters of GJ channels, can be internalized to ...
GLI proteins are bifunctional DNA-binding proteins that reco...
GLI1 expression is promoted by the binding of the full-lengt...
GLI1 is a direct target of the GLI transcription factors and...
GLI1 is recruited to the NUMB:ITCH complex through a direct ...
GLI1 is recruited to the NUMB:ITCH complex through a direct ...
GLI1 is the most divergent of the 3 mammalian GLI transcript...
GLI1 is ubiquitinated by ITCH and subsequently degraded by t...
GLI1 protein is degraded by the proteasome in the absence of...
GLI2 interacts directly with beta-TrCP and is polyubiquitina...
Gli2 is degraded in a proteasome-dependent manner after phos...
GLI3R is a DNA-binding transcriptional repressor that recogn...
GLI3R is a DNA-binding transcriptional repressor that recogn...
GLP-1R that has bound GLP-1 activates the alpha subunit of t...
Glucagon (Thomsen J et al, 1972) is an important peptide hor...
Glucagon and insulin are peptide hormones released from the ...
Glucagon inhibits the secretion of ghrelin in humans by an u...
Glucagon-like peptide 2 (GLP-2) (Drucker DJ 1999) is a 33-aa...
Glucagon-like Peptide-1 (GLP-1) is secreted by L-cells in th...
Glucagon-like Peptide-1 is synthesized in intestinal L-cells...
Glucokinase (GCK1) is negatively regulated by glucokinase re...
Glucokinase (GCK1) reversibly binds glucokinase regulatory p...
Glucosamine-fructose 6-phosphate aminotransferases 1 and 2 (...
Glucose 1-phosphate and UTP are the precursors to UDP-glucur...
Glucose 6-phosphate is hydrolyzed to yield glucose and phosp...
Glucose and orthophosphate generated within the endoplasmic ...
Glucose enters and leaves cells by facilitated diffusion acr...
Glucose enters cells by facilitated diffusion across the pla...
Glucose generated within the endoplasmic reticulum is export...
Glucose inhibits ghrelin secretion by an unknown mechanism. ...
Glucose is the major form in which dietary sugars are made a...
Glucose leaves cells by facilitated diffusion across the pla...
Glucose phosphate isomerase catalyzes the reversible convers...
Glucose phosphate isomerase catalyzes the reversible convers...
Glucose-6-phosphatase (G6PC) associated with the inner face ...
Glucose-6-phosphatase 2 (G6PC2), associated with the endopla...
Glucose-6-phosphatase 3 (G6PC3) associated with the endoplas...
Glucose-6-phosphate (G6P) activates the phosphorylated ("b")...
Glucuronate and N-acetylglucosamine exit the lysosome into t...
Glucuronidation conjugation utilizes UDP-glucuronosyltransfe...
GluR1-containing AMPA receptors are delivered to the synapse...
GluR2 containing AMPA receptors are constitutively recycled ...
GluR2 containing AMPA receptors are trafficked to the plasma...
GLUT (glucose transporter) homotetramers associated with the...
GLUT (glucose transporter) homotetramers associated with the...
GLUT1:ATP complexes reversibly dissociate, restoring the glu...
GLUT2 (glucose transporter) homotetramers associated with th...
Glut4 (Slc2a4) initially translocates from endosomes to insu...
Glutamate from the mitochondrial matrix is transported back ...
Glutamate synaptic vesicle contains Rab3 ( GTPase), synaptob...
Glutamic-pyruvate transaminase 2 (alanine aminotransferase 2...
Glutamic-pyruvate transaminase 2 (alanine aminotransferase 2...
Glutamine at position 636 is replaced by arginine in an edit...
Glutamine from the astrocytes is exported to the extracellul...
Glutamine in neurons is transported into mitochondrial matri...
Glutamine uptake in neurons is carried out by Na+-dependant ...
Glutathione (GSH) scavenges nitrosyl, yielding S-nitrosoglut...
Glutathione is exported out of the cell to be made available...
Glutathione is taken up by the bacterium by an ABC transport...
Glutathione peroxidase 1 (GPX1) (Bryant et al. 1982, Sutherl...
Glutathione peroxidase 1 (GPX1) (Bryant et al. 1982, Sutherl...
Glutathione peroxidase 1 (GPX1) (Bryant et al. 1982, Sutherl...
Glutathione peroxidase 1 (GPX1) located in the mitochondrial...
Glutathione peroxidase 3 (GPX3) in plasma reduces hydrogen p...
Glutathione peroxidase 7 (GPX7) and GPX8 are atypical glutat...
Glutathione peroxidases (GPXs) in human platelets (either GP...
Glutathione reductase (GSR) in the mitochondrial matrix rege...
Glutathione S-Transferases (GSTs; EC 2.5.1.18) are another m...
Glycerol can be a source for glycerol-3-phosphate, in which ...
Glycerol-3-phosphate (G3P) is acylated to 1-acyl lysophospha...
Glycerol-3-phosphate (G3P) is acylated to 1-acyl lysophospha...
Glycerophospholipids are important structural and functional...
Glycine amindinotransferase, localized to the mitochondrial ...
Glycoconjugates have to translocate to the cytosol for degra...
Glycoconjugates have to translocate to the lysosomal lumen f...
Glycogen storage disease type II (GSD II - Pompe’s disease) ...
Glycogen synthase 1 (GYS1) catalyzes the incorporation of ph...
Glycogen synthase 2 (GYS2) catalyzes the incorporation of ph...
Glycogen, a highly branched glucose polymer, is formed and b...
Glycogenin 1 (GYG1) catalyzes its autoglycosylation reaction...
Glycogenin 1 (GYG1) catalyzes its autoglycosylation reaction...
Glycogenin 2 (GYG2) catalyzes its autoglycosylation reaction...
Glycogenin 2 (GYG2) catalyzes its autoglycosylation reaction...
Glycolipid transfer protein (GLTP) is a monomeric, soluble p...
Glycoprotein VI (GPVI) was identified as a collagen receptor...
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransfer...
Glycoproteins with lesser folding defects get transported ba...
Glycosaminoglycans (GAGs) are long, unbranched polysaccharid...
Glycosylation of NA occurs within the endoplasmic reticulum ...
Glycosylphosphatidyl inositol (GPI) acts as a membrane ancho...
Glycosylphosphatidyl inositol (GPI) acts as a membrane ancho...
Glyoxylate is generated in the course of glycine and hydroxy...
GM-CSF and IL-3 application lead to Ser-585 phosphorylation ...
GMP (guanosine monophosphate) is synthesized in two steps fr...
GMP capped mRNA transcript dissociates from GT for further m...
GORASP1 (GRASP65) and GOLGA2 (GM130) form a complex on cis-G...
GORASP2 (GRASP55) localizes to the median region of Golgi, w...
GP1b-IX-V interacts with filamin-1; within the cytoplasmic d...
GP96 (also known as GRP94, HSP90b1), a paralogue of HSP90 in...
GPI moieties are synthesized anchored to dolichol phosphate ...
GPR120 is a receptor for many unsaturated long-chain free fa...
GPR17, an orphan receptor at intermediate phylogenetic posit...
GPR18 (GPRW) is a receptor for the biologically active anand...
GPR31 binds with high affinity the 12-lipoxygenase-derived p...
GPR37 and GPR37L1 are almost exclusively expressed in the ne...
GPR37L1 and GPR73 are almost exclusively expressed in the ne...
GPR77 (C5L2) has been described as a receptor for the chemot...
GPVI downstream signaling involves PI3K. Mouse knockouts of ...
GPVI receptor has little affinity for soluble forms of colla...
GPX2 (located in the gastrointestinal tract, also called GPX...
Graves disease carrier protein (SLC25A16), associated with t...
Grb14 is also one of the signaling partners of Tie2. The SH2...
GRB2 (Growth factor receptor-bound protein 2) binds to GAB1 ...
Grb2 binds directly to autophosphorylated Tie2 receptor. GRB...
Grb2 binds to phosphorylated tyrosine residues in SIRP alpha...
Grb2 bound to tyrosine phosphorylated FRS2 forms a ternary c...
GRB2 can be recruited indirectly to KIT through SHP2 (Tauchi...
GRB2 can bind EGFR directly or through another SH2-containin...
GRB2 is an adapter protein that contains a central SH2 domai...
GRB2 is an adapter protein that contains a central SH2 domai...
GRB2 is an adapter protein with one SH2 domain and two SH3 d...
Grb2 is an adaptor molecule containing one SH2 domain and tw...
Grb2 stabilizes the Shc/SHIP complex (Harmer & DeFranco 1999...
GRB2-bound SOS promotes the formation of active GTP-bound RA...
GRB2:SOS1 complex binds to phosphorylated tyrosine residue Y...
Grb7 an adapter protein contains a single SH2 domain, a plec...
Grb7 was initially identified as an EGF receptor binding pro...
GRIK2 is edited at the Q/R site at 621 where the glutamine i...
GRK2 can inhibit GPCR signaling via phosphorylation-independ...
GRK2 is a Serine/Threonine kinase. G-protein-coupled recepto...
GRK2 is phosphorylated at serine 29 in vitro and in vivo by ...
GRKs are serine/threonine kinases that phosphorylate GPCRs l...
Groucho/TLE mediates repression of WNT target genes in part ...
Group 3 members (SLC26A7 and 9) function as ion channels. SL...
Group II chaperonins enclose substrate proteins following su...
Growth hormone (Somatotropin or GH) is a key factor in deter...
Growth hormone is typically used to refer to the endogenous ...
Growth hormone-releasing hormone (GHRH, somatocrinin, growth...
GSH acts as a feedback inhibitor of the cycle because it can...
GSK3 (glycogen synthase kinase-3) participates in the Wnt si...
GSK3-mediated phosphorylation of GLI3 is primed by earlier p...
GSK3beta is subject to in-frame missplicing in CML stem cell...
GSK3beta mRNA is subject to aberrant splicing in stem cells ...
GST-tagged bovine Rhodopsin binds to His-tagged mouse Asap1 ...
GTP cyclizes in a reaction involving radicals of S-adenosylm...
GTP-AMP phosphotransferase, also called Adenylate kinase 3 c...
GTP-bound active forms of RHO GTPases RHOA, RHOG, RAC1 and C...
GTP-bound RHO GTPase RHOQ (TC10) binds GOPC (also known as P...
GTPase-activating protein (GAP) has two SH2 domains which bi...
Guanine nucleotide exchange factors (GEFs) activate GTPases ...
Guanine nucleotide releasing factor Sos associates with FAK ...
Guanine nucleotide-binding protein G(i) alpha (Gi-alpha) inh...
Gz is predominantly expressed in the nervous system and plat...
GZMB (granzyme B) cleaves BID to produce a p15 truncated for...
GZMB (granzyme B) promoter contains several RBPJ binding ele...
H2AX phosphorylation (producing the gamma-H2AX protein form...
H4R3me2s is a direct binding target for the DNA methyltransf...
HA receptors mediate the uptake of HA into cells. CD44 consi...
Haptoglobin is an acute phase protein. It is produced by the...
Haptoglobin-related protein (HRP) is present in human serum ...
HARS (cytosolic histidyl tRNA synthetase) catalyzes the reac...
HARS2 (mitochondrial histidyl tRNA synthetase) catalyzes the...
HCAR1 (GPR81) binds L-lactate (2-hydroxy-propanoic acid) (Ca...
HCAR2 (Niacin receptor 1, GPR109A) is activated by 3-hydroxy...
HCAR3 (GPR109B) is activated by 3-hydroxyoctanoic acid (3HO)...
HCN channels are activated upon hyperpolarization of membran...
HCN channels require cAMP binding and hyperpolarization of ...
HDAC1 and HDAC2 interact to form the catalytic core of sever...
HDAC10 is a class IIb HDAC subfamily member with greatest se...
HDAC3 mediates the gene silencing activity of Retinoic acid ...
HDAC6 is a microtubule-associated deacetylase that targets t...
HDAC8 can catalyze the in vitro deacetylation of a number of...
HDAC8 deacetylates cohesin in prometaphase, after cohesin di...
HDL particles play a central role in the reverse transport o...
Heat shock factor 1 (HSF1) is a transcription factor that ac...
Heat shock factor binding protein 1 (HSBP1) is a nuclear loc...
Heat-shock 70kDa proteins (HSP70s) are a family of conserved...
Heat-shock protein of 90 kDa (HSP90) a molecular chaperone, ...
Heat-shock protein of 90 kDa (HSP90) recruited to VEGFR2 ini...
Heat-stable antigen (HSA/mouse CD24) is expressed in both ha...
HECW1, also known as NEDL1, is an HECT E3 ligase that co-imm...
Hedgehog (Hh) is a secreted morphogen that regulates develop...
Hedgehog is a secreted morphogen that has evolutionarily con...
HEK293 cells were transiently transfected with constructs en...
Heme A is the prosthetic group of cytochrome c oxidase, the ...
Heme iron from the oxygenase domain of eNOS can reduce the B...
Heme O and heme A are specifically synthesised for the heme-...
Heme oxygenase (HO) cleaves the heme ring at the alpha-methe...
Heme proteins, especially the truncated globin GlbN in Mt...
Hemi-channels appear to play a role in isosmotic cell volum...
Hemi-channels consist of a single connexon and permit direc...
Hemidesmosomes (HDs) are specialized multiprotein junctional...
Hemopexin binds either ferriheme b or ferroheme b, however t...
Hemostasis is a physiological response that culminates in th...
Henmt1 transfers a methyl group from S-adenosylmethionine to...
Henmt1 transfers a methyl group from S-adenosylmethionine to...
Henmt1 transfers a methyl group from S-adenosylmethionine to...
Heparan sulfate (HS) and heparin (sometimes collectively cal...
Heparan sulfate (HS) is involved in regulating various body ...
Heparan sulfate (HS) is involved in regulating various body ...
Heparan sulfate 3-O-sulfotransferase1 (HS3ST1) transfers sul...
Heparan sulfate 3-O-sulfotransferases (HS3ST2-6) transfer su...
Heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT) ace...
Heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT) ace...
Heparan-sulfate 6-O-sulfotransferases 1 and 2 (HS3ST1-2) (H...
Heparanase (HPSE) is an endoglycosidase that cleaves heparan...
Heparanase 2 (HPSE2) (McKenzie et al. 2000) is a membrane-bo...
Hephaestin oxidizes ferrous iron after export from duodenal ...
Hepoxilins are biologically relevant signalling molecules pr...
Here we show that the activation of TBK1 occurs via an autop...
Heterocyclic and aromatic amines require metabolic activatio...
Heterodimerization with CFLAR is able to activate CASP8 and ...
Heterodimers of ERBB2 and ERBB3 are able to bind GRB7 (Fidde...
Heterotrimeric influenza viral polymerase complex consisting...
Hexoses like glucose, galactose and fructose serve as basic ...
Hexoses, notably fructose, glucose, and galactose, generated...
HFz6 represses Wnt-3a-induced canonical signaling when co-ex...
Hh ligands undergo a autoproteolytic cleavage mediated by a ...
Hh pathway activation depends upon the binding of Hh ligand ...
Hh signaling induces phosphorylation of full-length GLI that...
Hh signaling is required for a number of developmental proce...
Hh signaling is required for a number of developmental proce...
Hh signaling promotes the dissociation of the GLI:SUFU compl...
Hh signaling promotes the removal of the orphan G protein co...
Hh stimulation promotes PTCH1 clearance from the primary cil...
Hh-Np can be untethered from the plasma membrane of the secr...
Hh-Np traffics to the plasma membrane where it may cluster i...
HHIP is a Hh-binding transmembrane protein that antagonizes ...
HIF (heterodimer of HIF-alpha and HIF-beta) recruits p300 an...
HIF-alpha (HIF1A, HIF2A (EPAS1), HIF3A) forms a heterodimer ...
HIF-alpha (HIF1A, HIF2A (EPAS1), HIF3A) is translocated to t...
HIF-alpha is translocated into the nucleus (Kallio et al. 19...
HIF-alpha subunits, comprising HIF1A (Bruick and McKnight 20...
HIF1A binds the RORA promoter and enhances transcription.
HIF1AN (FIH, FIH-1) catalyzes the hydroxylation of an aspara...
HIF1AN (FIH, FIH-1) forms a homodimer that hydroxylates an a...
High concentrations of active CDC42 and Beta-Pix may promote...
High levels of the end product, BH4, negatively regulates GC...
High shear stress, or immobilization of VWF under high shear...
High-resolution structures of free, catalytically active yea...
Higuchi et al. (2008) and Keestra et al. (2007) demonstrated...
HIP-55 is an actin binding SH3 domain protein that is cleave...
Histamine H2 receptors (Gantz I et al, 1991) are primarily l...
Histamine H3 receptor (Lovenberg TW et al, 1999) is predomin...
Histamine is a biogenic amine involved in local immune respo...
Histidino-hydroxylysinonorleucine (HHL) cross-links, formed ...
Histone acetyltransferases (HATs) involved in histone modifi...
Histone deacetylase HDAC8 deacetylates SMC3 cohesin subunit....
Histone demethylase KDM6B (JMJD3) demethylates H3K27Me3 mark...
Histone demethylases (HDMs) belong to two groups with distin...
Histone H3 arginine-9 (H3R8) dimethylation is a PRMT5-specif...
Histone H3 is symmetrically dimethylated on arginine-3 by PR...
Histone lysine demethylases (KDMs) are able to reverse N-met...
Histone mRNAs are exported by a mechanism that requires TAP,...
Histone mRNAs are exported by a mechanism that requires TAP,...
Histones H3.1 and H3.2 are upregulated during DNA replicatio...
Histones in silenced rRNA gene copies are deacetylated by Hd...
HIV can infect non-dividing cells, implying that the PIC mus...
HIV enters cells by fusion at the cell surface, that results...
HIV is characterized by the production of multiple-spliced R...
HIV-1 genomic RNA contains a centrally located PPT (cPPT) wi...
HIV-1 infection of target cells depends on the sequential in...
HIV-1 uncoating is a poorly understood process. It likely in...
Hnf1a (Tcf1) has been shown to activate the Glut2 gene in ra...
Hnf1a (Tcf1) has been shown to activate the Liver-type pyruv...
HNF1a was shown to bind a 3'-region of the Foxa3 (Hnf3g) gen...
Hnf1a was shown to bind Hnf4g gene by chromatin immunoprecip...
Hnf1a was shown to bind the Hnf4a promoter by chromatin immu...
HNP-1 is recognized as a substrate by arginine-specific ADP-...
Holoprosencephaly (HPE) is a congenital brain disorder that ...
Homodimeric ABCD1 associated with the peroxisomal membrane m...
Homodimers and heterodimers of phosphoryated Stat5a and Stat...
Homodimers and/or heterodimers of PARP1 and PARP2 bind singl...
Homodimers of ERBB4 CYT 1 isoforms trans autophosphorylate o...
Homologous recombination in vertebrates is catalyzed by Rad5...
Homologous recombination repair of replication-independent d...
Homotetramers of Kir 1.1 function as inwardly rectifying po...
How the PIC finds favored sites on target DNA has not been f...
HRR is a major DNA repair pathway that acts on DSBs and inte...
HSP90 facilitates the CaM-induced displacement of caveolin f...
HSP90 interacts with the amino terminus of eNOS (amino acids...
HSP90 serves as a scaffold to promote productive interaction...
HSPG2 (perlecan) is a modular proteoglycan primarily located...
HSPG2 protein (perlecan) consists of a core protein of molec...
HSPG2 protein (perlecan) consists of a core protein of molec...
hTERC is transcribed as a precursor and is processed at its ...
Human ABCG4 shows sequence homology to the Drosophila white ...
Human amine oxidases (AO) catalyze the oxidative deamination...
Human and mouse MafA/RIPE3b1 bind to the insulin promoter in...
Human apo opsin proteins covalently bind the chromophore 11-...
Human Argonaute-2 (AGO2, EIF2C2) possesses ribonucleolytic a...
human beta-defensin (hBD)4A and 103 interact with CCR2, a ch...
Human biotinidase (BTD, EC 3.5.1.12) (Cole et al. 1994) cata...
Human biotinidase (BTD, EC 3.5.1.12) (Cole et al. 1994) cata...
Human Ca2+/calmodulin-dependent phosphodiesterase PDE1 is a...
Human chorionic gonadotropin (hCG) is a glycoprotein hormone...
Human CYP4F12 is involved in metabolism of endogenous compou...
Human factor B is cleaved by factor D yielding a small fragm...
Human ficolin-2 (L-ficolin, P35 or FCN2) is synthesised in t...
Human Frataxin binds about 7 iron atoms (Yoon and Cowan 2003...
Human glucosylceramidase (GBA) hydrolyses the glucosidic bon...
Human glucosylceramidase 2 (GBA2) hydrolyses the glucosidic ...
Human glucosylceramidase 3 (GBA3) hydrolyses the glucosidic ...
Human growth hormone (GH) is a heterogeneous protein hormone...
Human heparan sulfate L-iduronyl 2-O-sulfotransferase 1 (HS2...
Human Hippo signaling is a network of reactions that regulat...
Human homologues 2 and 3 (TTYH2 and 3) mediate the efflux of...
Human IL-5 is a disulphide-linked homodimer with 115 amino-a...
Human immunodeficiency virus (HIV) Nef is a membrane-associa...
Human IRF-3 is activated through a two step phosphorylation ...
Human IRF3 is activated through a two-step phosphorylation i...
Human kinesin-7, or CENP-E was one of the first kinesins to ...
Human MKK3 and MKK6 are two closely related dual-specificity...
Human monoamine oxidases (MAOs) are flavin-containing enzyme...
Human mtDNA is transcribed by a dedicated mitochondrial RNA ...
Human neutrophils contain thousands of cytoplasmic granules....
Human NOTCH1 was cloned as a chromosome 9 gene, translocated...
Human NOTCH1 was cloned as a chromosome 9 gene, translocated...
Human NPC1L1, associated with the plasma membrane, binds eze...
Human opsin-2 is a G-protein coupled photoreceptor found in ...
Human p38 MAPK alpha forms a complex with MK2 even when the ...
Human pancreatic beta cells contain GLUT1 and GLUT2 transpor...
Human pancreatic beta cells contain Kv2.1, Kv3.2, Kv6.2, and...
Human pancreatic beta cells express glucose transporters 1 a...
Human PLK1 from HeLa cell extracts binds recombinant rat Gor...
Human PRLR binds at least 3 related peptide ligands namely p...
Human Protein kinase C beta (PKC-beta) is activated by calci...
Human replication protein A (RPA) is a single-stranded DNA (...
Human reproduction mixes the genomes of two individuals crea...
Human serum urate levels are largely maintained by its reabs...
Human SL1 does not bind to DNA itself, rather it is recruite...
Human SL1 is a four subunit complex composed of the TATA-bin...
Human SLC5A5 encodes a Na+/I- symporter, NIS (Smanik et al. ...
Human vitronectin interacts with C5b:C6:C7 complex preventin...
Humans and mice have 19 identified WNT proteins that were or...
Humans are exposed to millions of potential pathogens daily,...
Humans can perceive thousands of compounds as bitter-tasting...
Humans have 38 beta-defensin genes plus 9-10 pseudogenes (de...
Humans have 7 alpha defensin genes plus 5 pseudogenes (see H...
Humans, like most eukaryotic organisms, add direct repeats t...
HuR (ELAV1) phosphorylated on serine221 and serine158 binds ...
HuR (ELAVL1) is a ubiquitous protein that binds AU-rich elem...
HuR (phosphorylation state unknown) binds AU-rich elements i...
HuR binds AU-rich elements of mRNAs. Bound HuR can form olig...
HuR interacts with SETalpha (Template activating factor 1), ...
HuR phosphorylated on ser221 and ser318 binds AU-rich region...
Hyaluronan (HA) turnover can occur locally at the tissue of ...
Hyaluronan (hyaluronic acid, HA) is composed of repeating di...
Hyaluronan (hyaluronic acid, hyaluronate or HA) is an anioni...
Hyaluronidase 1 (HYAL1) hydrolyses 1-4 linkages between GalN...
Hyaluronidases are only active in acidic environments. HYAL2...
Hydrogen peroxide is generated in the course of peroxisomal ...
Hydrogen peroxide is released from mitochondria at a rate th...
Hydrolysis of eIF2-GTP occurs after the Met-tRNAi has recogn...
Hydrolysis of phosphatidyl inositol-bisphosphate (PIP2) by p...
Hydrolysis of trehalose phosphate, catalyzed by OtsB2, gives...
Hydrolytic deamination of adenosine leads to inosine. Ammoni...
Hydrolytic deamination of cytidine leads to uridine. Ammonia...
Hydrophobic compounds such as long-chain fatty acids (LCFAs)...
Hydroxyallysine and hydroxylysine can react forming the Schi...
Hydroxyindole-O-methyltransferase (HIOMT) catalyzes the last...
Hydroxylysine glycosides are specific to collagen. Collagen ...
Hydroxylysines residues can be converted to hydroxyallysines...
Hydroxylysyl-pyridinoline (HL-Pyr) is formed from three hydr...
Hydroxymethybilane (HMBL) can spontaneously cyclize and rear...
Hydroxymethylglutaryl-CoA lyase dimer (HMGCL) in the mitocho...
Hydroxymethylglutaryl-CoA synthase tetramer (HMGCS2) in the ...
Hydroxysteroid (17-beta) dehydrogenase 12 (HSD17B12) catalyz...
Hyperphosphorylated GLI3 binds directly with beta-TrCP thoug...
Hyperphosphorylated IRAK1 and TRAF6 are thought to dissociat...
Hyperphosphorylated IRAK1, still within the receptor complex...
Hyperpolarization-activated and cyclic nucleotide gated (HCN...
Hypoxia causes an increase in the level of HIF3A which in tu...
Hypoxia inhibits myogenic differentiation of the mouse cell ...
Hypoxia-inducible factor binds the promoter of the CA9 gene ...
I kappa B kinase B (IKBKB or IKK beta) is the catalytic subu...
I-SMAD selectively antagonizes BMP-activated Smad1/5/9 by ac...
I-SMADs (SMAD6 and SMAD7) reside in the nucleus presumably t...
I-SMADs reside in the nucleus presumably to be sequestered f...
IARS (cytosolic aspartyl tRNA synthetase) catalyzes the reac...
IARS2 (mitochondrial isoleucyl tRNA synthetase) catalyzes th...
Identified as a component of amyloid plaques in Alzheimer's ...
Iduronate 2-sulfatase (IDS) hydrolyses 2-sulfate groups from...
Iduronate 2sulfatase (IDS) hydrolyses 2-sulfate groups from ...
If a damaged double strand DNA (dsDNA) is not repaired prior...
If AMP:ATP ratio rises, AMP (instead of ATP) is bound by the...
If MAN2 acts before MGAT3, the pathway progresses to complex...
IFN-gamma binding to the receptor complex, induces JAK2 auto...
IFN-gamma stimulates gene expression of about 200 genes whic...
IFNA-activated-factor (AAF) translocates to nucleus and then...
IFT particles were first characterized in Chlamydomonas rein...
IFT20 is a member of the IFT B anterograde complex that is r...
IFT20 is unique among IFT B components in that, in addition ...
IGFBP 1 binds IGF I or IGF II via the conserved N terminus a...
IGFBP 2 binds IGF I or IGF II via the conserved N terminus a...
IGFBP 4 binds IGF I or IGF II via the conserved N terminus a...
IGFBP 5 binds IGF I or IGF II via the conserved N terminus a...
IGFBP-6 binds IGF I or IGF II via the conserved N terminus a...
IGFBP3 binds IGF I or IGF II via the conserved N terminus an...
IkB is an inhibitory protein that sequesters NF-kB in the cy...
IKK-mediated NFkB p105 phosphorylation generates a binding s...
IL-1 Beta lacks signal sequences for compartmentation within...
IL-2 receptor gamma chain (IL2RG) associates with Janus Kina...
IL-3, IL-5 and GM-CSF all induce tyrosine phosphorylation of...
IL-6 activates the tyrosine phosphorylation of STATs (Akira ...
IL-6-type receptor activation leads to induction of the MAPK...
IL1 induces the poly-ubiquitination and degradation of IRAK1...
IL17RD, or SEF, is a negative regulator of FGF signaling. T...
IL1R/TLR induces the Lys48- polyubiquitination and proteosom...
IL3 stimulation induces rapid and transient tyrosine-phospho...
IL7 receptor signaling is presumed to resemble that of other...
IL7RA has the small juxta-membrane "Box1" motif, conserved t...
ILK interacts with the cytoplasmic domain of beta1-integrin ...
Immature, clathrin-coated vesicles containing proinsulin-zin...
Immediately after assembly in the ER nonameric (alpha beta:I...
Immune receptor expressed by myeloid cells 2 (IREM-2), is a ...
Immunoprecipitation and kinase activity experiments demonstr...
Important functional domains in dermatan or dermatan sulfate...
Importin-8 (IPO8, IMP8, RANBP8) binds AGO2:miRNA complexes i...
In S. cerevisiae the dehydratation of 5'-methylthio ...
In a healthy adult human, about 500 mg of cholesterol is con...
In a healthy adult human, about 500 mg of cholesterol is con...
In a healthy, well-nourished individual, the production of k...
In a mechanism that is presumed to be analagous to signaling...
In a murine mouse model of ZNF198-FGFR1-induced EMS, treatme...
In a small percent of T-ALL patients, the translocation t(7;...
In a yeast two-hybrid screen of a HeLa cDNA library using fu...
In acidic conditions, hyaluronidase 2 (HYAL2), a membrane-an...
In addition to AGER/RAGE, several other proteins have been i...
In addition to being modified by cholesterol at its C-termin...
In addition to fucosylation of NOTCH receptor precursors, gl...
In addition to fucosylation of Notch receptor precursors, gl...
In addition to its association with Cdh1 in G1 phase, Emi1 f...
In addition to its role converting leukotriene A4 (LTA4) int...
In addition to recruiting proteins and complexes necessary f...
In addition to regulating Rho family proteins, the EPH recep...
In addition to regulating the level of unstimulated ERBB3, u...
In addition to repressing WNT-dependent targets through Grou...
In addition to serving as a scaffold via auto-phosphorylatio...
In addition to telomerase-mediated elongation and C-strand s...
In addition to telomerase-mediated elongation and C-strand s...
In addition to the activation of canonical NF-kB subunits, a...
In addition to the main fibril peptide, mature amyloid fibri...
In addition to the membrane remodeling for pseudopod extensi...
In addition to the methylation of the 5'-cap, there is methy...
In addition to tyrosine phosphorylation, STAT1 and STAT3 un...
In addition to various processes for removing lesions from t...
In adipocytes and myocytes insulin signaling causes intracel...
In adipocytes and myocytes insulin signaling causes intracel...
In an affinity cross-linking assay performed in COS7 cells t...
In an analogous reaction to the formation of leukotriene D4 ...
In an analogous reaction to the formation of leukotriene E4 ...
In an ATP-dependent reaction, ABCG1 mediates the movement of...
In an ATP-dependent reaction, ATPA1 mediates the movement of...
In an ATP-dependent reaction, ATPA1 mediates the movement of...
In analogy to glutathione, mycothiol is part of the detoxifi...
In anaphase, the paired chromosomes separate at the centrome...
In apoptotic cells, intercellular contacts are disrupted th...
In articular cartilage the major non-fibrous macromolecules ...
In astrocytic glutamate-glutamine cycle, the excess glutamat...
In bone, cross-links are formed between telopeptide hydroxal...
In bovine experiments, phosphorylation of RGS9-1 (at Ser475,...
In brain, a complex of three proteins form a tripartite comp...
In budding yeast, all MCM proteins have been proved to be es...
In capillaries of the lungs erythrocytes release carbon diox...
In certain cell types, ligand binding to p75NTR leads to cer...
In chicken, TLR1 and 2 genes are individually duplicated to ...
In Chinese hamster ovary (CHO) cells, recombinant mouse Notc...
In Chinese hamster ovary (CHO) cells, recombinant mouse Notc...
In Chinese hamster ovary (CHO) cells, recombinant mouse Notc...
In Chinese hamster ovary (CHO) cells, recombinant mouse Noth...
In contrast to NOD1/2 some NLRPs function as large macromole...
In COS-1 cells, recombinant mouse Strap binds the complex of...
In darkness, the G protein transducin (Gt) is attached to th...
In darkness, the heterotrimeric G protein transducin (Gt) is...
In Drosophila, mutations that lead to the loss of function o...
In drosophila, the calcium channel flower (fwe) is a homomul...
In Drosophila, tissue specific overexpression of both Krz (K...
In dsDNA-stimulated human and mouse cells TBK1 has been show...
In EGFRvIII mutant, Y1045 (Y1069) is not phosphorylated (Han...
In eight cycles of beta-oxidation mediated by the same enzym...
In enterocytes, all-trans-retinal (atRAL) binds to RBP2 (CRB...
In enterocytes, the dominant retinol-binding protein is RBP2...
In epithelial cells, desmosomes are anchoring junctions that...
In female vertebrates, estrogens control reproductive system...
In females, lutropin (LH) can trigger ovulation whereas in m...
In fish, amphibian and avian species, ATP1B4 (aka X,K-ATPase...
In G0 and early G1 in quiescent cells, p130 (RBL2) bound to ...
In G0 and early G1, expression of E2F target genes such as C...
In G0 and early G1, p130 (RBL2) bound to E2F4 or E2F5 and DP...
In G2 Cdk2, in association with cyclin A, phosphorylates E2F...
In G2, the cyclin A:Cdk2 complex associates with E2F1 and E2...
In general, nucleotides and cysteinyl-leukotrienes (CysLTs) ...
In germ cells of humans and mice, precursors of PIWI-interac...
In glioblastoma, the most prevalent EGFR mutation, present i...
In growing cells, the transcription of EED gene, which codes...
In growing cells, the transcription of EZH2 methyltransferas...
In healthy cells, BMF is bound to the myosin V motor complex...
In human embryonic kidney cell line, HEK293, TGFBR2 binds TG...
In human liver and kidney tissue, monomeric peroxisomal ACOX...
In human, IkB is an inhibitory protein that sequesters NF-kB...
In Human, IKKs - IkB kinase (IKK) complex serves as the mast...
In human, phosphorylation of MKK4 and MKK7 by TAK1 occurs at...
In human, RIG-I-like receptor (RLR) family is crucial for tr...
In human, small amounts of hydrolyzed C3 (C3(H20) or C3i) ar...
In human, small amounts of hydrolyzed C3 (C3(H20) or C3i) ar...
In human, ten members of the Toll-like receptor (TLR) family...
In human, together with ubiquitin-conjugating E2-type enzyme...
In humans and other mammals the NOTCH gene family has four m...
In humans induction of acrosome reaction is mediated by ADAM...
In humans the deamination of adenosines to inosines is the m...
In humans there are three main arginine vasopressin receptor...
In humans, creatine is synthesized primarily in the liver an...
In humans, most catabolism of L-lysine normally proceeds via...
In humans, newly synthesized histone H4 is acetylated by the...
In humans, the catabolism of phytanate, pristanate, and very...
In humans, the IkB kinase (IKK) complex serves as the master...
In humans, the IkB kinase (IKK) complex serves as the master...
In humans, the IKKs - IkB kinase (IKK) complex serves as th...
In humans, the NOTCH protein family has four members: NOTCH1...
In humans, the phosphorylated adaptor protein Sprouty2 is ub...
In humans, the phosphorylated MNK1 kinase phosphorylates the...
In its active (unphosphorylated) form, ChREBP (Carbohydrate ...
In its bound state PAK dimers are arranged in head-to-tail f...
In its unphosphorylated state, the WWTR1 (TAZ) transcription...
In its unphosphorylated state, the YAP1 transcriptional coac...
In K cells of the intestine the transcription factors PAX6 a...
In L cells of the intestine the transcription factors TCF-4 ...
In late anaphase/early telophase, dephosphorylated BANF1 (BA...
In late G1, cyclin D dependent kinases CDK4 and CDK6 phospho...
In late mitosis, Cdc20 dissociates from the APC/C and is rep...
In low concentrations of cholesterol SCAP interacts with Sec...
In macrophages, LL-37 expression is stimulated by contact wi...
In mammalian cells, many antioxidant defence systems exist w...
In mammalian cells, many antioxidant defence systems exist w...
In mammalian cells, PRMT5 is tightly bound by WDR77 (MEP50)....
In mammals activated IRAK4 phosphorylates both IRAK1 and IRA...
In mammals, C3b binds covalently to a specific site on the C...
In mammals, C3b binds covalently to a specific site on the C...
In mammals, C6 interacts with C5b through a metastable bindi...
In mammals, C8 binds to the membrane-bound C5b:C6:C7 complex...
In mammals, complement C3a receptor (C3aR) is a member of th...
In mammals, complement C5a receptor (C5aR) is a member of th...
In mammals, extracellular factor H binds negatively-charged ...
In mammals, fluid-phase C3i interacts with factor B which, i...
In mammals, IKKs (IkB kinase complex) were shown to interact...
In mammals, inactivated C3b (iC3b) undergoes proteolytic cle...
In mammals, IRF3 and IRF7 (IRF3/IRF7) are the two major memb...
In mammals, LPS stimulation results in the formation of TLR4...
In mammals, polyprenol pyrophosphate (pPPP) requires dephosp...
In mammals, reactions following C5b formation are common to ...
In mammals, the alternative pathway is activated either by s...
In mammals, the classical pathway is initiated by binding of...
In mammals, the interaction of flagellin with TLR5 induces a...
In mammals, the response to viral infection is mediated thro...
In mammals, three pathways of complement activation - altern...
In mammals, three pathways of complement activation - altern...
In mammals, TLR7 and TLR8 belong to TLR9 subfamily and sense...
In mammals, virus-triggered RIG-1 or MDA5 receptor complex h...
In mature beta-cells of the pancreas, the NKX6-1 gene is tra...
In mice in the cytosol, glycerophosphocholine phosphodiester...
In mice in the cytosol, glycerophosphocholine phosphodiester...
In mice in the endoplasmic reticulum (ER) membrane, phosphol...
In mice, another non-enzymatic dehydration of prostaglandin ...
In mice, phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) t...
In mice, phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) t...
In mice, prostaglandin reductase 2 (Ptgr2) is a 13-prostagla...
In mice, prostamide/prostaglandin F synthase, Fam213b and th...
In milk, caseins (CSNs) interact with calcium phosphate (CaP...
In mitotic prophase, chromatin detaches from the nuclear env...
In mitotic prophase, the action of the condensin II complex ...
In mitotic telophase, as chromosomes decondense, cohesin com...
In models of COPI coat assembly and disassembly, after GBF1 ...
In mouse 3T3-L1 cells, by 10 days after induction of adipocy...
In mouse 3T3-L1 cells, the PPARG:RXRA heterodimer binds spec...
In mouse 3T3-L1 cells, the transcription factors Cebpb, Cebp...
In mouse 3T3-L1 pre-adipocytes, Cebpa is expressed during ad...
In mouse 3T3-L1 pre-adipocytes, expression of the Cebpb and ...
In mouse 3T3-L1 pre-adipocytes, increased expression of Klf5...
In mouse B cells both Rasgrp1 and Rasgrp3 are activated by b...
In mouse CD8+ T-lymphocytes, Notch2 intracellular domain, NI...
In mouse either Per2 or Per1 is sufficient to maintain circa...
In mouse retina, Ccnd1 (cyclin D1) forms a complex with Creb...
In mouse, by 10 days after induction of adipocyte differenti...
In murine L929 cells Dai dimer formation enables recruitment...
In muscle cells such as cardiac, skeletal, vascular and nonv...
In myeloid cells BTK is phosphorylated on Y551 upon DAP12 ac...
In myoblasts, CDO forms cis complexes with the cell–cell adh...
In naive T cells, CD28 costimulation enhances cell cycle ent...
In neuroendocrine cells such as pancreatic alpha-, beta-, an...
In neurons, Cables1 links Cdk5 and c-Abl, enhancing Cdk5 tyr...
In neutrophils, RAC2 regulates NADPH oxidase NOX2 complex (K...
In non-muscle cells, phosphorylation of myosin II regulates ...
In normal cells and in the early stages of cancer developmen...
In normal development vascular endothelial growth factors (V...
In nucleotide excision repair (NER) endonucleases incise the...
In one model of Vpr mediated induction of apoptosis, Vpr act...
In order for repair of the double-strand break to occur, the...
In order for Rev to function, multiple molecules must bind s...
In order to facilitate the transport of incompletely spliced...
In order to get a sulfur atom for subsequent sulfuration rea...
In parallel sequences of three reactions each, thymine is co...
In pigs, prostaglandin reductase 1 (PTGR1) aka LTB4DH metabo...
In pigs, prostaglandin reductase 1 (PTGR1) aka LTB4DH, a 15-...
In plasmacytoid dendritic cell induction of type I IFNs crit...
In preparation for internalisation, the gastric intrinsic fa...
In preparation for internalisation, the gastric intrinsic fa...
In primary adipocytes from young rats and in adipocytes deri...
In primary cultured human umbilical vein endothelial cells (...
In proliferating cells, Cables1 links Cdk2 and Wee1, a dual ...
In pyrimidine salvage reactions, nucleosides and free bases ...
In rabbits, 15-hydroxyprostaglandin dehydrogenase (HPGD) oxi...
In rat pancreatic beta cells adrenergic stimulation causes L...
In rats at the inner mitochondrial membrane (IM), calcium-in...
In rats, at the inner mitochondrial (IM) membrane, CDP-diacy...
In rats, at the inner mitochondrial (IM) membrane, phosphati...
In rats, phosphatidic acid (PA) transport within the mitocho...
In rats, transport of phosphatidylethanolamine (PE) occurs v...
In rats, transport of phosphatidylserine (PS) occurs via mem...
In response to apoptotic signals, mitochondrial proteins ar...
In response to DNA damage due to exposure to ultraviolet lig...
In response to DNA damage due to ionizing radiation, the ser...
In response to exposure to elevated temperature and certain ...
In response to insulin Akt2 phosphorylates Myosin 5a on seri...
In response to muscle contraction and insulin signaling, AMP...
In response to receptor ligation, the tyrosine residues in D...
In response to stress signals, the p21-activated protein kin...
In response to stress-activated p38 signaling, MAPKAPK3 phos...
In response to TGF-beta stimulation, a complex composed of S...
In response to the TCR stimulation, phsophoinositides are ph...
In response to VEGF, the increased actin polymerization requ...
In response to WNT signaling, DVL is recruited to the CUL3:K...
In response to WNT signaling, DVL proteins are phosphorylate...
In S. aureus, rather than cause gross membrane changes, HNP-...
In S. cerevisiae, two ORC subunits, Orc1 and Orc5, both bind...
In Saccharomyces cerevisiae, the entire ORC complex is const...
In secretory granules of intestinal L cells, proglucagon is ...
In somatic cells where telomerase is not active, telomeric D...
In stress situations, Mycobacteria express enzymes for a sec...
In the early phase of HIV lifecycle, an active virio...
In the de novo synthesis of phosphatidic acid (PA), l...
In the absence of a WNT signal, many WNT target genes are re...
In the absence of activating ligands of PPAR-alpha, the PPAR...
In the absence of Hh ligand, the Hh receptor PTCH inhibits s...
In the absence of Hh signal, GLI1 is degraded by the proteas...
In the absence of Hh signaling, the majority of full-length ...
In the absence of NICD1, RBPJ (CSL) is bound to a co-repress...
In the absence of stress HSF1 is predominantly monomeric and...
In the absence of Tat, transcriptional elongation beyond pos...
In the absence of the HIV-1 protein Tat, transcription of th...
In the absence of TLR agonist 'priming', inflammasome depend...
In the absence of TLR agonist 'priming', inflammasome depend...
In the absence of WNT signal, AXIN is a phosphoprotein; cand...
In the acid environment of the lysosome, hyaluronidase 1 (HY...
In the acidic compartments of MIICs the empty MHC II molecul...
In the acyl chain remodelling pathway (Lands cycle), phosph...
In the acyl chain remodelling pathway (Lands cycle), phospha...
In the acyl chain remodelling pathway (Lands cycle), phospha...
In the acyl chain remodelling pathway (Lands cycle), phospha...
In the acyl chain remodelling pathway (Lands cycle), phospha...
In the bloodstream, circulating retinol binding protein 4 (R...
In the body, 24-hydroxycholesterol is synthesized in the bra...
In the body, 27-hydroxycholesterol is synthesized in multipl...
In the body, aspirin (acetylsalicylic acid) is hydrolyzed to...
In the body, this binding involved apoE synthesized by hepat...
In the case of actin and tubulin folding, and perhaps other ...
In the case of AGO2 (EIF2C2), cleavage of one strand (the "p...
In the cases of spliced, polyadenylated mRNA transcribed fro...
In the cis-Golgi, Man7, Man8 or Man9 N-glycans are progressi...
In the citric acid or tricarboxylic acid (TCA) cycle, the ac...
In the classical and lectin-mediated pathways C3 convertase ...
In the complement cascade, a panel of soluble molecules rapi...
In the cytoplasm activated MEK1 (Serine phosphorylated) may ...
In the cytoplasm activated MEK2 (Serine phosphorylated) may ...
In the cytoplasm of unstimulated cells, SOS1 is found in a c...
In the cytosol of human embryonic stem cells, WWTR1 (TAZ) bi...
In the cytosol the kinases casein kinase I delta (Csnk1d) an...
In the cytosol the kinases CSNK1D (casein kinase I delta) an...
In the cytosol, a ubiquitin hydrolase USP9X (FAM) binds to u...
In the cytosol, choline kinase alpha subunit (CHKA) homodime...
In the cytosol, choline O-acetyltransferase (CHAT) acetylate...
In the cytosol, ethanolamine (ETA) is phosphorylated to phos...
In the cytosol, glycerophosphocholine phosphodiesterase (GPC...
In the cytosol, glycerophosphocholine phosphodiesterase (GPC...
In the cytosol, phosphoethanolamine (PETA) is dephosphorylat...
In the cytosol, the PDZ domain of Dishevelled (DSH) binds to...
In the cytosol, the phosphoethanolamine/phosphocholine phosp...
In the detoxification of formaldehyde, mycothiol first binds...
In the direct inhibition model, association of the MCC with ...
In the direct inhibition model, the cytosolic Mitotic Checkp...
In the disc membranes of photoreceptor outer segments, all-t...
In the early elongation phase, shorter transcripts typically...
In the eighth reaction of GPI synthesis, a third mannose res...
In the endoplasmic reticulum (ER) lumen, inositol phosphates...
In the endoplasmic reticulum (ER) lumen, multiple inositol p...
In the endoplasmic reticulum (ER) lumen, multiple inositol p...
In the endoplasmic reticulum (ER) lumen, multiple inositol p...
In the endoplasmic reticulum (ER) membrane, phospholipase D1...
In the endoplasmic reticulum, glycosyl transferases modify N...
In the endoplasmic reticulum, NOTCH receptor precursors are ...
In the endoplasmic reticulum, Notch receptor precursors are ...
In the endoplasmic reticulum, the precursor form of urokinas...
In the execution phase of apoptosis, effector caspases cleav...
In the fifth step of GPI synthesis, a mannose residue is add...
In the final step of the capping reaction, the methyltransfe...
In the first catalytic step of mRNA splicing, the 2' OH grou...
In the first committed step of N-glycan precursor (LLO) synt...
In the first of two salvage steps to maintain BH4 levels in ...
In the first part of reverse transcription, minus-strand syn...
In the first step of N glycan precursor (LLO) synthesis, N a...
In the first step of PAPS biosynthesis, ATP and sulfate reac...
In the first step the precursor apha-linolenic (9,12,15-18:3...
In the formation of mercapturic acid from glutathione conjug...
In the fourth step of GPI synthesis, an acyl group (typicall...
In the G1 phase there are two types of DNA damage responses,...
In the G2 phase of the cell cycle, cyclin A (CCNA) and B (CC...
In the Golgi apparatus, TGF-beta-1 (TGFB1) is activated by f...
In the Golgi membrane, the B4GALT1 subunit of the B4GALT1:LA...
In the host cell nucleus, the viral negative-strand RNA (vRN...
In the immune system, Sema4D/CD100 binds CD72 to mediate B-c...
In the initial response to injury, platelets adhere to damag...
In the kidney water and solutes are passed out of the bloods...
In the last step MOB gets transaminated to methionine. (Ber...
In the last step MOB gets transaminated to methionine. The r...
In the last step of the N-glycan precursor biosynthesis path...
In the last step, the beta subunit is converted to the open ...
In the latter compartments of the distal Golgi the N-Glycan ...
In the liver, synthesis of bile acids and bile salts is init...
In the lysosome, gastric intrinsic factor (GIF) bound to cob...
In the mouse myogenic cell line C2C12, transfected with a fu...
In the mucosal cells of the distal ileum, in preparation for...
In the non-activated state heterotrimeric G proteins exist a...
In the nucleus the mouse Wwtr1 (Taz) transcriptional coactiv...
In the nucleus the WWTR1 (TAZ) transcriptional coactivator c...
In the nucleus the WWTR1 (TAZ) transcriptional coactivator c...
In the nucleus the WWTR1 (TAZ) transcriptional coactivator c...
In the nucleus the YAP1 transcriptional coactivator can bind...
In the nucleus, activated AMPK phosphorylates serine residue...
In the nucleus, all-trans-retinoic acid (atRA), bounds to ep...
In the nucleus, cellular retinoic acid binding protein 2 (CR...
In the nucleus, inositol hexakisphosphate kinase 1 (IP6K1) a...
In the nucleus, inositol hexakisphosphate kinase 1 (IP6K1) a...
In the nucleus, inositol hexakisphosphate kinase 1 (IP6K1) a...
In the nucleus, inositol hexakisphosphate kinase 1 (IP6K1) a...
In the nucleus, inositol hexakisphosphate kinase 1 (IP6K1) a...
In the nucleus, inositol polyphosphate multikinase (IPMK) ph...
In the nucleus, inositol polyphosphate multikinase (IPMK) ph...
In the nucleus, inositol polyphosphate multikinase (IPMK) ph...
In the nucleus, inositol polyphosphate multikinase (IPMK) ph...
In the nucleus, inositol-pentakisphosphate 2-kinase (IPPK - ...
In the nucleus, MKL1 binds SRF transcription factor and enab...
In the nucleus, NICD1 PEST domain mutants are expected to di...
In the nucleus, NICD2 forms a complex with RBPJ (CBF1, CSL) ...
In the nucleus, NICD2 forms a complex with RBPJ (CBF1, CSL) ...
In the nucleus, protein type 2C phosphatase, PPM1A, dephosph...
In the nucleus, SMAD2/3:SMAD4 heterotrimer complex acts as a...
In the pancreatic beta cell, alpha2 adrenergic receptors are...
In the presence of FLIP(L), both caspase-8 and FLIP(L) are r...
In the presence of high concentrations of zinc and calcium, ...
In the presence of high glucose concentrations, the complex ...
In the presence of Netrin1, DCC and UNC5 generate attractive...
In the presence of oxygen members of the transcription facto...
In the presence of sulfhydryl compounds such as cysteine, do...
In the presence of the proteasome inhibitor MG132, polyubiqu...
In the proximal intestine, pancreatic enzymes degrade transc...
In the resting state the luminal domain of STIM1 binds Ca2+ ...
In the second salvage step, dihydrofolate reductase (DHFR) c...
In the second step in glutathione formation, gamma-glutamylc...
In the second step in the formation of glutathione, gamma-gl...
In the second step of GPI synthesis, N-acetylglucosaminyl-PI...
In the second step of PAPS biosynthesis, adenylyl sulfate (A...
In the second step of the formation of leukotriene A4 (LTA4)...
In the second step, FDFT catalyzes the reduction of presqual...
In the sequestration model, the Mad2 molecules that dissoci...
In the seventh reaction of GPI synthesis, a second mannose r...
In the sixth step of GPI synthesis, a phosphoethanolamine gr...
In the synthesis-dependant strand-annealing (SDSA) model of ...
In the target cell, HIV-1-associated APOBEC3G binds to the H...
In the tight configuration, the beta subunit catalyzes the r...
In this pathway, the viral integration machinery uses a sit...
In this complex Axin is bound to beta-catenin.
In this complex, PARD3:PARD6A:PRKCZ is bound to JAM-A. JAM-A...
In this electrical synapse the current generated in the pres...
In this electrical synapse the current generated in the pres...
In this electrical synapse the current generated in the pres...
In this electrical synapse the current generated in the pres...
In this final phase of mitosis, new membranes are formed aro...
In this form of the destruction complex, beta-catenin is no ...
In this freely reversible cytosolic reaction, dihydroxyaceto...
In this irreversible reaction, the activated C1r subunit of ...
In this module, the biology of various types of regulatory n...
In this module, the processes by which calcium binding trigg...
In this reaction, 1 molecule of 'ADP' i...
In this reaction, 1 molecule of 'cytidi...
In this reaction, 1 molecule of 'Export...
In this reaction, 1 molecule of 'GDP' i...
In this reaction, 1 molecule of 'H+' is...
In this reaction, 1 molecule of 'phosph...
In this reaction, 1 molecule of 'phosph...
In this reaction, 1 molecule of 'phosph...
In this reaction, 1 molecule of 'phosph...
In this reaction, 1 molecule of 'pro-fa...
In this reaction, 1 molecule of 'pro-fa...
In this reaction, 1 molecule of 'pro-fa...
In this reaction, 1 molecule of 'pro-GA...
In this reaction, 1 molecule of 'pro-pr...
In this reaction, 1 molecule of 'pro-pr...
In this reaction, 1 molecule of 'pro-pr...
In this reaction, 1 molecule of 'pro-pr...
In this reaction, 1 molecule of 'thiore...
In this reaction, 1 molecule of 'Thiore...
In this reaction, 1 molecule of 'ubiqui...
In this reaction, 1 molecule of 'uridin...
In this reaction, FGF receptor 2b in the plasma membrane bin...
In this reaction, FGF receptor 2c in the plasma membrane bin...
In this reaction, FGF receptor in the plasma membrane binds ...
In this reaction, FGF receptor in the plasma membrane binds ...
In this two-step reaction catalyzed by 3beta-HSD associated ...
In tissues other than the duodenum, ceruloplasmin (CP), in c...
In tumor cells the Polycomb Repressor Complex 2 associates w...
In two cycles of beta-oxidation mediated by the same enzyme ...
In unstimulated cells, APC is K63 polyubiquitinated in a man...
In unstimulated cells, SPRY2 has been shown to be phosphoryl...
In unstimulated mouse 3T3-L1 adipocytes, perilipin is locali...
In untreated cells both STAT1 and STAT3 are distributed diff...
In view of the highly variable nature of antibody proteins, ...
In view of the highly variable nature of T-cell receptors, t...
In vitro binding of MafA to a conserved 5'-flanking region o...
In vitro protein binding experiments have shown that mammali...
In vitro structural studies have shown that Mad2 undergoes a...
In vitro studies of telomerase complexes derived from multip...
In vitro studies using purified NLRP1 and caspase-1 suggest ...
In vitro, telomerase can disassociate from the primer follow...
In vivo type X collagen is found associated with cartilage f...
In ZAP-70 there are multiple phosphorylation sites (Y292, Y3...
Inactivating mutations in TGF-beta receptor II (TGFBR2) are ...
Inactivating mutations of cytosolic phenylalanine hydroxylas...
Inactive Arf1-GDP then diffuses away from the membrane, init...
Inactive eIF2:GDP binds eIF2B to form an eIF2:GDP:eIF2B inte...
Inactive p21-associated kinases (PAKs), PAK1, PAK2 and PAK3,...
Inactive p21ras-GDP is found anchored to the plasma membrane...
Inactive PAK-2 can be partially autophosphorylated in the re...
Inactive PAK-2 is partially autophosphorylated at 5 serine s...
Inactive phospholipase C-gamma1 (PLCG1) binds to activated e...
Inactive Raf-1 is associated in the cytoplasm with 14-3-3. 1...
Inborn errors of interferon immunity due to defects in toll ...
Increase in intracellular concentration of Ca2+ ions and mem...
Increase of intracellular calcium in mast cells is most cruc...
Increased activity of CDK1:CCNB1 during the cell cycle promo...
Increased Ca2+ levels, acting via calmodulin, can activate P...
Increased expression of KLF5 occurs after activation of the ...
Increased PAK1-3 catalytic activity is associated with autop...
Increases in intracellular calcium and calmodulin stimulate ...
Incretins are peptide hormones produced by the gut that enha...
Inducible acetylation of HSF1 at Lys80 within the DNA bindin...
Inducible T cell co-stimulatory (ICOS) protein is the third ...
Induction of inflammatory cytokines in response to poly(I:C)...
Infection by Mycobacterium tuberculosis (Mtb) ...
Infection of a human host cell with influenza virus triggers...
Inferred from mouse homologs, RAI1 increases transcription o...
Influenza A virus induces apoptosis in a variety of ways inc...
Influenza A virus induces apoptosis in a variety of ways inc...
Influenza A virus induces apoptosis in a variety of ways inc...
Influenza A virus nonstructural protein 1 (NS1A) is a multif...
Influenza genomic RNA (vRNA), synthesized in the nucleus of ...
Influenza virus buds preferentially from lipid rafts (Scheif...
Influenza virus inhibits the host double-stranded-RNA-activa...
Influenza virus's non-structural protein (NS1) binds to the ...
Influenza viruses assemble and bud from the apical plasma me...
Influenza viruses bind via their surface HA (hemagglutinin) ...
Inhibitory phosphate groups that were added to condensin I s...
Initial activation of SMO in response to HH occurs with the ...
Initial binding and phosphorylation of the SMO C-terminal ta...
Initiation of platelet adhesion is the first step in the for...
Initiation of recombination precedes and is required for syn...
Initiation of recombination precedes and is required for syn...
Initiation of synthesis of the viral genomic RNA (vRNA) is t...
Initiation of translation in the majority of eukaryotic cell...
Initiation protein Cdt1 was first identified in X. laevis, w...
Initiation/Cargo Recognition is mediated by ESCRT-0, a heter...
Injury to the eye's surface provokes an inflammatory respons...
Innate immune responses are coordinated and regulated to pro...
Innate immunity also known as nonspecific immunity provides ...
Innate immunity encompases the nonspecific part of immunity ...
Inositol 1,2,3,4,5,6-hexakisphosphate (IP6) translocates fro...
Inositol 1,2,3,4,5,6-hexakisphosphate (IP6) translocates fro...
Inositol 1,3,4,5,6-pentakisphosphate (I(1,3,4,5,6)P5) transl...
Inositol 1,3,4,5,6-pentakisphosphate I(1,3,4,5,6)P5 transloc...
Inositol 1,3,4,5,6-pentakisphosphate I(1,3,4,5,6)P5 transloc...
Inositol 1,3,4,5,6-pentakisphosphate I(1,3,4,5,6)P5 transloc...
Inositol 1,3,4,5-tetrakisphosphate (I(1,3,4,5)P4) translocat...
Inositol 1,3,4,5-tetrakisphosphate (I(1,3,4,5)P4) translocat...
Inositol 1,3,4,6-tetrakisphosphate (I(1,3,4,6)P4) translocat...
Inositol 1,4,5,6-tetrakisphosphate (I(1,4,5,6)P4) translocat...
Inositol 1,4,5-triphosphate (IP3) is a second messenger prod...
Inositol 1,4,5-trisphosphate (I(1,4,5)P3) translocates from ...
Inositol 1,4,5-trisphosphate (I(1,4,5)P3) translocates from ...
Inositol 1,5-bisdiphospho-2,3,4,6-tetrakisphosphate (1,5-(PP...
Inositol 5-diphospho-1,2,3,4,6-pentakisphosphate (5-PP-IP5) ...
Inositol 5-diphospho-1,3,4,6-tetrakisphosphate (5-PP-IP4) tr...
Inositol hexakisphosphate and diphosphoinositol-pentakisphos...
Inositol hexakisphosphate and diphosphoinositol-pentakisphos...
Inositol hexakisphosphate kinase 1 (IP6K1) and 3 (IP6K3) pho...
Inositol hexakisphosphate kinase 1 (IP6K1) and 3 (IP6K3) pho...
Inositol hexakisphosphate kinase 1 (IP6K1) and 3 (IP6K3) pho...
Inositol hexakisphosphate kinase 1 (IP6K1) and 3 (IP6K3) pho...
Inositol hexakisphosphate kinase 1 (IP6K1) and 3 (IP6K3) pho...
Inositol monophosphatase 1 (IMPA1) and 2 (IMPA2) homodimers ...
Inositol monophosphatase 1 (IMPA1) and 2 (IMPA2) homodimers ...
Inositol monophosphatase 1 (IMPA1) and 2 (IMPA2) homodimers ...
Inositol phosphate IP6 is imported to the endoplasmic reticu...
Inositol phosphates (IPs) are molecules involves in signalli...
Inositol phosphates (IPs) synthesised in the nucleus are imp...
Inositol phosphates IP2, IP and the six-carbon cyclic alcoho...
Inositol phosphates IP3 and IP5 are imported into the cytoso...
Inositol phosphates IP4 and IP5 are exported from the endopl...
Inositol phosphates IP4, IP5, and IP6 are exported from the ...
Inositol phosphates such as IP4, IP5 and IP6 are converted t...
Inositol polyphosphate 1-phosphatase (INPP1) dephosphorylate...
Inositol polyphosphate 1-phosphatase (INPP1) dephosphorylate...
Inositol trisphosphate (IP3) and tetrakisphosphate (IP4) mol...
Inositol-3-phosphate synthase 1 (ISYNA1) aka hIPS isomerises...
Inositol-tetrakisphosphate 1-kinase (ITPK1) can phosphorylat...
Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates...
Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates...
Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates...
Inositol-tetrakisphosphate 1-kinase (ITPK1) phosphorylates I...
Inositol-tetrakisphosphate 1-kinase (ITPK1) phosphorylates i...
Inositol-tetrakisphosphate 1-kinase (ITPK1) phosphorylates i...
Inositol-tetrakisphosphate 1-kinase (ITPK1) phosphorylates I...
Inositol-trisphosphate 3-kinase A (ITPKA), B (ITPKB), and C ...
Inositolpentakisphosphate 2-kinase (IPPK), also known as IP5...
Inositoltetrakisphosphate 1-kinase (ITPK1) phosphorylates in...
INPP5E is a ciliary peripheral membrane protein that is asso...
Insertion of a connexon into the cell membrane results in th...
Insertion of the N-terminal fusion peptide of the HIV gp41 p...
Inside the nucleus, Ran-GTP associates with importin-beta.
INSIG binds oxysterols and the INSIG:oxysterol complex inter...
INSIG binds oxysterols and the INSIG:oxysterol complex inter...
Insulin binding to its receptor results in receptor autophos...
Insulin causes phosphorylation and inactivation of the Ral G...
Insulin Glulisine, a fast acting analogue of human insulin, ...
Insulin inhibits secretion of ghrelin by an unknown mechanis...
Insulin is composed of the A chain and B chain from proinsul...
Insulin signals via PKC-lambda to cause Rab4 to load GTP an...
Insulin was markedly reduced in one Pax6 mutant model (Sande...
Insulin-containing secretory granules are bound to Myosin Va...
Insulin-containing secretory granules are bound to Myosin Va...
Insulin-containing secretory vesicles are translocated along...
Insulin-containing secretory vesicles are translocated along...
Insulin-like Growth Factor mRNA Binding Factor-1 (IGF2BP1, a...
Insulin-like Growth Factor mRNA Binding Factor-2 (IGF2BP2, a...
Insulin-like Growth Factor mRNA Binding Factor-3 (IGF2BP3, a...
Insulin-like growth factor-1 stimulates secretion of ghrelin...
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs)...
Intact ERBB4 isoforms and their membrane bound and cytosolic...
Integrin alpha10beta1 binds collagen types I, IV and VI with...
Integrin alpha10beta1 binds collagen types I, IV, and VI wit...
Integrin alpha1beta1 binds to collagen type IV and VI with h...
Integrin alpha1beta1 binds to collagen type IV and VI with h...
Integrin alpha1beta1 is a negative feedback regulator of col...
Integrin alpha2beta1 and alpha1beta1 both bind collagen type...
Integrin alpha9beta1 is widely expressed on smooth muscle, e...
Integrin alphaDbeta2 is a member of the beta2 family. It is ...
Integrin alphaIIb beta3 'outside-in' signalling involves mul...
Integrin alphaIIbbeta3 (glycoprotein IIb-IIIa, GP IIb-IIIa) ...
Integrin alphaVbeta3 interacts with von Willebrand factor (v...
Integrin alphaVbeta3 is highly expressed on osteoclasts, bon...
Integrin alphaVbeta3 is sometimes referred to as the 'vitron...
Integrin alphaVbeta3 receptor has been implicated in various...
Integrin alphaXbeta2 serves as a cell surface receptor for f...
Integrin signaling is linked to the MAP kinase pathway by re...
Integrin signaling is linked to the MAP kinase pathway by re...
Integrin-associated protein (IAP or CD47) is a receptor for ...
Integrins play a central role in mediating lymphocyte adhe...
Interaction of calnexin (CNX) with MHC class I HC stabilizes...
Interaction of E3 with both substrate and E2-Ub, brings them...
Interaction of Filamin with Migfiln mediates the association...
Interaction of RBPJ (CSL) with NCOR2 (SMRT) was initially di...
Interaction of TGFBR2 kinase domain (KD) mutants with TGFBR1...
Interaction of the cognate aminoacyl-tRNA in the A-site with...
Interaction with ankyrins mediates the lateral oligomerizati...
Interaction with ERM may lead to lateral oligomerization of ...
Interferon (IFN)-inducible IFI16 protein was shown to be cri...
Interferon regulatory factor 2 (IRF-2) represses the action ...
Interferon regulatory factor-1 (IRF-1) is a positive transcr...
Interferon regulatory factors (IRF) IRF-3 and IRF-7 are the ...
Interferon Synthesis is inhibited.
Interferon-gamma (IFN-gamma) belongs to the type II interfer...
Interferon-stimulated gene 15 (ISG15) is a member of the ubi...
Interferons (IFNs) are cytokines that play a central role in...
Intergenic spacer regions (IGS) located between rRNA transcr...
Interleukin 1 (IL1) signals via Interleukin 1 receptor 1 (IL...
Interleukin receptor 1 type 1 when bound to interleukin 1 bi...
Interleukin-1 receptor type 1 (IL1R1) is the receptor respon...
Interleukin-1 receptor type 2 (IL1R2) binds Interleukin-1 bu...
Interleukin-1 receptor-associated kinase 4 (IRAK4) is a seri...
Interleukin-1beta (IL1B) is secreted as inactive precursor, ...
Interleukin-2 (IL-2) is a cytokine that is produced by T cel...
Interleukin-6 (IL-6) is a pleiotropic cytokine with roles in...
Interleukin-6 site I interacts with the non-sigaling but lig...
Interleukin-7 (IL7) is produced primarily by T zone fibrobla...
Interleukin-7 receptor alpha chain (IL7R) binds interleukin-...
Interleukins are low molecular weight proteins that bind to ...
Intermediate conductance K+ channels are restricted to non n...
Intermedin (AM2) (Roh J et al, 2004) and adrenomedullin (AM)...
Internalization of FZD2, FZD5 and ROR2 after WNT5A binding i...
Internalized GJ plaques are degraded by lysosomes. Lysosomal...
Interphotoreceptor retinoid-binding protein (RBP3) is the ma...
Intersectin-1 (ITSN1), a guanine nucleotide exchange factor ...
Intersectin-1, a guanine nucleotide exchange factor (GEF) fo...
Intracellular alkalinization is essential for the initiation...
Intracellular Ca2+ is extruded from the outer segment by a N...
Intracellular foreign or aberrant host proteins are cleaved ...
Intracellular pools of Ca2+ serve as the source for inositol...
Intracellular vesicles bearing phosphorylated Aquaporin-2 te...
Intraflagellar transport (IFT) is a motor-based process that...
Intrapancreatic parasympathetic (vagal) nerve endings releas...
Inwardly rectifying G protein activated K+ channels (GIRK) a...
Inwardly rectifying K+ channels (Kir channels) show an inwar...
Inwardly rectifying potassium transport are tetrameric chann...
Iodide (I-) is transported from blood serum into the thyroid...
Iodothyronine deiodinases 1 and 2 (DIO1/2) are the vertebrat...
Ion channels mediate the flow of ions across the plasma memb...
Ion channels that mediate sensations such as pain, warmth, c...
Ionizing radiation (IR) induces single-strand breaks i.e. cl...
Ionizing radiation induced DNA double strand breaks often co...
Ionizing radiation results in an ATM-dependent movement of C...
IP3 promotes the release of intracellular calcium after init...
IP3 promotes the release of intracellular calcium.
IPAF contains an N-terminal CARD domain, a central nucleotid...
IPS-1 interacts with TRAF2 and TRAF6 through its consensus T...
IPS-1/MAVS/Cardif/VISA with its TRAF-interaction motif (TIM)...
IQCE and EFCAB7 are ciliary proteins that are required to re...
IQGAP proteins IQGAP1, IQGAP2 and IQGAP3 bind F-actin filame...
IQGAP proteins IQGAP1, IQGAP2 and IQGAP3 possess IQ repeats ...
IQGAP proteins IQGAP1, IQGAP2 and IQGAP3, bind Rho GTPases R...
IQGAP1 binds the complex of E-cadherin (CDH1), beta-catenin ...
IQGAP1, an effector protein of the small GTPases Rac1 and Cd...
IQGAPs constitute a family of scaffolding proteins character...
IRAG, PKG1(cGKI), and IP3 receptor type 1 can be isolated as...
IRAK-2 has two TRAF6 binding motifs that are responsible for...
IRAK1 and 4 can phosphorylate Pellino-1 and -2 and probably ...
IRAK1 and 4 interact with Pellino-1 (Jiang et al. 2003), 2 (...
IRAK1 is recruited to the TLR complex through binding with I...
IRAK2 has been implicated in IL1R and TLR signaling by the o...
IRAK4 deficient macrophages fail to induce IRAK2 phosphoryla...
IRAK4 is activated by autophosphorylation at 3 positions wit...
IRAK4 is the mammalian homolog of Drosophila melanogaster Tu...
IRAKM prevents the dissociation of IRAK1 and IRAK4 from MYD8...
IRE1 is trans-autophosphorylated after dissociation from BiP...
Ire1 phosphorylated in the activation domain preferentially ...
IRE1-alpha is a single-pass transmembrane protein that resid...
IRE1-alpha is a single-pass transmembrane protein with a lum...
IRF-3 is activated by two step phosphorylation. IKK related ...
IRF3 and IRF7 (IRF3/IRF7) are the two major members of the i...
IRF3 and IRF7 associate with each other and they further int...
IRF3 is activated through a two-step phosphorylation in the ...
IRF3 phosphorylation promotes IRF3 dimerization and nuclear ...
IRF3-P:IRF3-P' is translocated from cytosol to nucleoplasm.
IRF3:CBP/p300 complex binds specifically to IFN-beta promote...
IRF7 and VAF transcription factors binds to IFN-alpha and IF...
IRF7 is activated through phosphorylation of residues Ser477...
IRF7 is phosphorylated on Ser477 and Ser479 residues [Lin R...
Iron-containing superoxide dismutase is localized both withi...
Iron-sulfur (Fe-S) proteins are localized in the cytosol, nu...
Iron-sulfur clusters are assembled on the scaffold, ISCU. Ba...
Iron-sulfur clusters containing 4 atoms of iron and 4 atoms ...
Iron-sulfur clusters containing 4 atoms of iron and 4 atoms ...
IRS is one of the mediators of insulin signalling events. It...
IRS1 and IRS2 are tyrosine phosphorylated at multiple YXXM m...
IRS1 and IRS2 bind directly to TRK receptors phosphorylated ...
IRS1 binds the NPEY-juxtamembrane motif of phosphorylated IG...
IRS1, IRS2 and IRS3 are all known to bind the regulatory sub...
Irs1/2 binds Sh2b1 within the Lep:Lepr:Jak2:Sh2b1 complex. T...
IRS2 binds the NPEY-juxtamembrane motif of phosphorylated IG...
IRS2 is required for AKT to phosphorylate FOXO1, which is th...
ISG15 is a ubiquitin (Ub)-like protein which is conjugated t...
ISG15 negatively regulates the scaffold protein filamin B. I...
Isocaproaldehyde (4-methylpentanal) is translocated from the...
Isocaproaldehyde is reduced by NADPH + H+ to yield 4-methyl...
Isomerization of the double bond in prostaglandin A2 (PGA2) ...
Isomerization of zymosterol to cholesta-7,24-dien-3beta-ol i...
It has been observed, however, that the oligomerization of C...
It has been shown that Xenopus polo homolog, Plx1, directly ...
It has not been directly demonstrated that DLL4 binds to and...
It has not been directly demonstrated that DLL4 binds to and...
It has not been directly demonstrated that JAG2 binds to and...
It has not been directly demonstrated that JAG2 binds to and...
It has not been directly shown that JAG1 binds to and activa...
It has not been directly shown that JAG1 binds to and activa...
It is assumed that TGFBR1 kinase domain (KD) mutants found i...
It is assumed that, upon phosphorylation, SMAD2/3 MH2 domain...
It is predicted that the target RNA could form secondary str...
It is still unclear how ADAR 1 and ADAR 2 proteins form the...
It is thought that due to its p53 dependence for expression,...
It was observed that cytosolic Noxa underwent BH3 motif-depe...
It's believed that TAK1 dissociates from the membrane in to ...
ITCH ubiquitinates DTX, targeting it for degradation.
ITCH, recruited to NOTCH1 indirectly through association wit...
ITK is a member of the Tec protein tyrosine kinase family wh...
Its also observed that DSCAM can activate p38 MAP kinase alo...
JAG1, expressed on a neighboring cell, binds NOTCH2 and acti...
JAG2, expressed on a neighboring cell, binds NOTCH2 and acti...
JAK2 activation results in the phosphorylation and activatio...
JAK2 associates with IL3 reecptor beta chain (IL3RB) better ...
Jak2 in the Lep:Lepr:Jak2:Sh2b1:Irs1/2 complex phosphorylate...
JAK2 is believed to bind STAT1 and STAT3 directly in respons...
JAK2 is required for GH-mediated phosphorylation of STATs 1,...
JAK2 is tyrosine phosphorylated in response to IL-3 (Silvenn...
JAK2 mutation V617F casues JAK2 to be constitutively activat...
JAK2 phosphorylates IRS1/2 after IRS1/2 binds SH2B1 in the L...
Jak2 phosphorylates Lepr at multiple tyrosine residues, incl...
Jak2 phosphorylates Shp2 within the Lep:Lepr:Jak2:Shp2 compl...
JAK2 phosphorylates STAT5; phosphorylated STAT5 dimerizes an...
JAKs bind to the box1 motif (residues 297-305) of the Growth...
JAM members, such as JAML, bind coxsackie and adenovirus re...
JAM-A plays a key role in leukocyte transmigration and infla...
JAM-C has been detected in epithelial-cell desmosomes. JAM-C...
JAM2 and JAM3 bind each other and are strongly expressed by ...
Janus Kinase 1 (JAK1) constitutively associates with IL-2R b...
Janus kinase 2 (JAK2) plays an important role in SCF induced...
JLP is a p38 alpha/beta MAPK scaffold protein. p38 alpha/bet...
JLP is a scaffold protein for the p38 MAPK pathway. During m...
JMJD1C specifically demethylates histone H3K9 mono- and di-m...
JNK (c-Jun N-terminal Kinase) phosphorylates several transcr...
Joining of the 60S subunit to form the 80S ribosome is catal...
Junctional channels are an assembly of two docked connexons ...
Just before final end joining, the bound repair proteins mus...
K+/Cl- cotransport is implicated not only in regulatory volu...
K-63 linked polyubiquitin (pUb) chain on TRAF6 provides a sc...
K-63 linked polyubiquitin (pUb) chain on TRAF6 provides a sc...
K48 polyubiquitinated substrate dissociates from E3 to becom...
K63-polyubiquitinated RIP2 is able to recruit the components...
Kainate receptor activation activates G protein coupled rece...
Kainate receptors are either Ca2+ permeable or impermeable d...
Kainate receptors are formed by the assembly of four subunit...
Kainate receptors are found both in the presynaptc terminals...
Kainate receptors bind glutamate in the ligand binding domai...
Kainate receptors in the presynaptic neuron are involved in ...
Kainate receptors that are assembled with subunits GRIK1-5, ...
Kainate receptors that are formed by subunits GRIK1 and or G...
KARS (cytosolic lysyl tRNA synthetase) catalyzes the reactio...
KARS (mitochondrial lysyl tRNA synthetase) catalyzes the rea...
KAT2A (GCN5) and KAT2B (PCAF) are histone acetyltransferases...
KAT2A (GCN5) and KAT2B (PCAF) are histone acetyltransferases...
Kat2b (Pcaf) and to a lesser extent Kat2a (Gcn5) acetylate t...
KAT6A (Monocytic leukemia zinc finger protein, MOZ) and KAT6...
KAT8 (MOF, MYST1) is a member of the MYST (Moz-Ybf2/Sas3-Sas...
KDM4C (JMJD2C) demethylates trimethylated lysine K10 of hist...
KDSR (3-ketodihydrosphingosine reductase) enzyme associated ...
KDSR (3-ketodihydrosphingosine reductase) enzyme associated ...
Keratan sulfate (KS) (a glycosaminoglycan, GAG) is a linear ...
Keratan sulfate (KS) is cleaved from its KS proteoglycan (KS...
Keratan sulfate (KSI) is the best characterised keratan sulf...
Keratan sulfate proteoglycans (KSPGs) are degraded in lysoso...
KIAA0101 (PAF15) is a PCNA-associated protein expressed duri...
Kif15 (human kinesin-12) is by analogy with orthologous prot...
KIF17 is an alternate kinesin-2 motor that is required in so...
KIF26A is atypical as it lacks ATPase activity.
KIF7, the human ortholog of Drosophila COS2, is a kinesin-4 ...
KIF9 has the coiled-coil domain typical of the dimeric kines...
KIF9 has the coiled-coil domain typical of the dimeric kines...
Killer cell immunoglobulin-like three-domain short-tail rece...
Killer cell immunoglobulin-like two-domain short-tail recept...
Killer cell immunoglobulin-like two-domain short-tail recept...
Killer cell immunoglobulin-like two-domain short-tail recept...
Killer cell immunoglobulin-like two-domain short-tail recept...
Kinases like Protein kinase C delta (PKC-delta) and Calcium/...
Kinectin, a kinesin anchor involved in kinesin-mediated vesi...
Kinesin-1 is a heterotetramer of two heavy chains (HCs) and ...
Kinesin-13 proteins are homodimeric with the kinesin motor i...
Kinesin-14 proteins have a C-terminal motor domain. At least...
Kinesin-2 is a heterotrimer with two different motor subunit...
Kinesin-3 drives the transport of synaptic vesicle precursor...
Kinesin-5 motors are bipolar homotetramers with two motor do...
Kinesin-8 is a plus-end-directed dimeric kinesin with an int...
Kinesins are a superfamily of microtubule-based motor prote...
Kinesins consume ATP to power the motor which allows them to...
Kininogen (high molecular weight kininogen; HK) associates w...
Kir 2 channels form heterotetramers of any two of the four ...
KLF4, PBX1, OCT4 (POU5F1), SOX2, and NANOG bind the promoter...
KLF4, PBX1, POU5F1 (OCT4), SOX2, and NANOG bind the promoter...
Knockdown of CSB reduces recruitment of SL1 and RNA Polymera...
Knocking down WWTR1 (TAZ) expression by siRNA treatment inhi...
Knocking down WWTR1 (TAZ) expression by siRNA treatment inhi...
Known as the "death receptor pathway" the extrinsic or caspa...
KSRP (KHSRP) binds AU-rich regions of target RNAs via its fo...
KSRP (KHSRP) forms a complex with the PARN deadenylase, exos...
KSRP binds an AU-rich element in the mRNA encoding IL-8 and ...
KSRP binds AU-rich elements in the following mRNAs: IL-8, LD...
KSRP binds to AU-rich sequences in the 3' untranslated regio...
KSRP is phosphorylated by activated protein kinase B/AKT at ...
KSRP phosphorylated at serine193 binds 14-3-3zeta (YWHAZ) wh...
Kurtz (Krz), encoded by the krz gene, is a Drosophila homolo...
Kynurenine/alpha-aminoadipate aminotransferase (AADAT) catal...
Kynurenine/alpha-aminoadipate aminotransferase (AADAT) catal...
L-ornithine is converted into putrescine by ODC holoenzyme c...
L-selectin plays a major role in leukocyte traffic through l...
L-Serine is needed in human brain in large amounts as precur...
L1 and NCAM1 co-expressed on a single cell interact with eac...
L1 and RanBPM interact with one another and the N-terminus o...
L1 can function as a trans-heterophilic ligand for multiple ...
L1 cross linking can activate MAPK cascade components MEK1/2...
L1 crosslinking leads to the tyrosine phosphorylation and ac...
L1 functions in many aspects of neuronal development includi...
L1 in the C-domain membrane is internalized via clathrin med...
L1 interacts with neuropilin 1 (NP-1) through a conserved se...
L1 recruits membrane skeletal component ankyrin to cell to c...
L1 translocated to the non raft membranes of the C-domain is...
L1 transported to the P-domain of growth cones is reinserted...
L1-L1 trans-homodimers interact with the fibroblast growth f...
L1CAM and EGFR engage in a weak heterophilic trans interacti...
L1CAM binds with high affinity to the proteoglycan neurocan....
L2HDGH associated with the mitochondrial inner membrane cata...
L858R, a substitution of leucine 858 with arginine, accounts...
L861Q, a substitution of leucine 861 with glutamine, is a do...
Lack of TCF2 disrupts early pancreas development. Specifical...
Lactoferrin is secreted from many tissues to collect stray i...
Lafora disease is a progressive neurodegenerative disorder w...
Laminin (LM) deposition onto the cell surface depends upon i...
Laminin is a large trimeric glycoprotein, found in all basem...
Laminin-332 (laminin-5) consists of laminin alpha-3, beta-3 ...
Laminin-bound nidogens can bind to type IV collagen (Aumaile...
Laminins are a large family of conserved, multidomain trimer...
Laminins are an important molecular component of the basemen...
Laminins are an important molecular component of the basemen...
Laminins are an important molecular component of the basemen...
Laminins are degraded by MMP3 (Okada et al. 1986, Bejanaro e...
Laminins bind to HSPG2 (perlecan) through interactions with ...
Laminins can be degraded by the membrane-associated metallop...
Lanosterol 14-alpha demethylase (CYP51A1) catalyses oxidativ...
Lanosterol