Reactome: A Curated Pathway Database

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Pathways reviewed by Kawai, T (434072)

DB_ID Name
168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta
918233 TRAF3-dependent IRF activation pathway
933542 TRAF6 mediated NF-kB activation
933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
933541 TRAF6 mediated IRF7 activation
936440 Negative regulators of DDX58/IFIH1 signaling

Details on Person Kawai, T

_displayNameKawai, T
_timestamp2017-08-22 20:41:39
created[InstanceEdit:434122] Shamovsky, V, 2009-08-26
modified[InstanceEdit:1964470] Shamovsky, V, 2011-11-04
(author)[LiteratureReference:438014] Essential function for the kinase TAK1 in innate and adaptive immune responses
[LiteratureReference:446698] Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2
[LiteratureReference:918205] Antiviral signaling through pattern recognition receptors
[LiteratureReference:933430] TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway
[LiteratureReference:933491] Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
[LiteratureReference:933506] Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA
[LiteratureReference:936421] The Atg5 Atg12 conjugate associates with innate antiviral immune responses
[LiteratureReference:936448] Inhibition of IRF3-dependent antiviral responses by cellular and viral proteins
[LiteratureReference:936495] Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
[LiteratureReference:1169578] Cross-linking of B cell antigen receptor-related structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase
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