Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Leprince, Dominique

Class:IdPerson:4090360
_displayNameLeprince, Dominique
_timestamp2017-08-22 20:45:12
created[InstanceEdit:4090291] May, B, 2013-08-13
firstnameDominique
initialD
surnameLeprince
(author)[InstanceEdit:8955684] Leprince, Dominique, 2017-01-12
[LiteratureReference:4090292] An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity
[LiteratureReference:5084074] Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins
[LiteratureReference:5084111] Functional characterization of human Polycomb-like 3 isoforms identifies them as components of distinct EZH2 protein complexes
[LiteratureReference:8953844] DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair
[LiteratureReference:8955676] HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs)
[LiteratureReference:8955677] Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells
[Change default viewing format]
No pathways have been reviewed or authored by Leprince, Dominique (4090360)