Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways reviewed by Peters, JM (174234)

DB_ID Name
141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
141430 Inactivation of APC/C via direct inhibition of the APC/C complex
174048 APC/C:Cdc20 mediated degradation of Cyclin B
174084 Autodegradation of Cdh1 by Cdh1:APC/C
174113 SCF-beta-TrCP mediated degradation of Emi1
174143 APC/C-mediated degradation of cell cycle proteins
174154 APC/C:Cdc20 mediated degradation of Securin
174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
176408 Regulation of APC/C activators between G1/S and early anaphase
176409 APC/C:Cdc20 mediated degradation of mitotic proteins
176412 Phosphorylation of the APC/C
176417 Phosphorylation of Emi1
176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
179409 APC-Cdc20 mediated degradation of Nek2A

Details on Person Peters, JM

Class:IdPerson:174234
_displayNamePeters, JM
_timestamp2017-08-22 20:38:12
created[InstanceEdit:174149] Matthews, L, 2006-02-17 00:41:48
initialJM
surnamePeters
(author)[InstanceEdit:177300] Peters, JM, 2006-03-27 22:55:09
[InstanceEdit:188369] Peters, JM, 2006-10-10 10:07:26
[LiteratureReference:174065] Mitotic regulation of the human anaphase-promoting complex by phosphorylation
[LiteratureReference:174075] Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint
[LiteratureReference:174096] Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1
[LiteratureReference:174165] The anaphase-promoting complex: proteolysis in mitosis and beyond
[LiteratureReference:174194] Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
[LiteratureReference:174245] Mitotic regulation of the APC activator proteins CDC20 and CDH1
[LiteratureReference:176424] How APC/C orders destruction
[LiteratureReference:176919] Splitting the chromosome: cutting the ties that bind sister chromatids
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