Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways authored by Pagano, Michele (174134)

DB_ID Name
69656 Cyclin A:Cdk2-associated events at S phase entry
187577 SCF(Skp2)-mediated degradation of p27/p21

Pathways reviewed by Pagano, Michele (174134)

DB_ID Name
195253 Degradation of beta-catenin by the destruction complex
196299 Beta-catenin phosphorylation cascade

Details on Person Pagano, Michele

_displayNamePagano, Michele
_timestamp2017-08-22 20:38:12
affiliation[Affiliation:1237447] NYU School of Medicine, Department of Pathology
created[InstanceEdit:174149] Matthews, L, 2006-02-17 00:41:48
modified[InstanceEdit:1237444] D'Eustachio, P, 2011-03-30
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[InstanceEdit:187509] Pagano, M, 2006-09-19 08:23:10
[InstanceEdit:196987] Pagano, M, 2007-04-27 13:02:18
[LiteratureReference:174111] The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin
[LiteratureReference:187515] Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation
[LiteratureReference:187517] SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
[LiteratureReference:187544] The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
[LiteratureReference:187566] Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase
[LiteratureReference:187825] Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation
[LiteratureReference:187842] Stabilizers and destabilizers controlling cell cycle oscillators
[LiteratureReference:187848] Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
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