Reactome: A Curated Pathway Database

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Pathways reviewed by Akira, Shizuo (168004)

DB_ID Name
168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta
918233 TRAF3-dependent IRF activation pathway
933542 TRAF6 mediated NF-kB activation
933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
933541 TRAF6 mediated IRF7 activation
936440 Negative regulators of DDX58/IFIH1 signaling

Details on Person Akira, Shizuo

_displayNameAkira, Shizuo
_timestamp2017-08-22 20:38:02
affiliation[Affiliation:1247342] Osaka University, Laboratory of Host Defense
modified[InstanceEdit:180262] D'Eustachio, P, 2006-05-17 15:28:14
[InstanceEdit:975210] Shamovsky, V, 2010-09-22
[InstanceEdit:1247344] D'Eustachio, P, 2011-04-01
[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
(author)[InstanceEdit:990527] Kawai, T, Akira, S, 2010-10-30
[LiteratureReference:168196] TIRAP/Mal, TRIF and TRAM. Differential utilization of these TIR
[LiteratureReference:168201] TIR domains, which are conserved among all TLRs. Recent accumulating
[LiteratureReference:169782] Toll-like receptor signaling
[LiteratureReference:180812] TLR signaling
[LiteratureReference:181039] Discrimination of bacterial lipoproteins by Toll-like receptor 6
[LiteratureReference:181127] Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
[LiteratureReference:181352] Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
[LiteratureReference:188053] The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
[LiteratureReference:188142] Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
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